HIV treatment in the criminal justice system

HIV therapy Pub Date : 2010-10-25 DOI:10.2217/HIV.10.43
M. Milloy, E. Wood
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Abstract

The advent of HAART has resulted in a dramatic decline in HIV-related morbidity and mortality among those accessing HIV treatment [1]. Fortunately, efforts to simplify regimens and scale up treatment systems have led to individuals being engaged in treatment in numbers and locales that were unimaginable just 10 years ago. Still, some seropositive populations have not benefited equally from advancements in HIV treatment. Studies of HIV-seropositive individuals who use injection drugs (IDU) on HAART confirm that adherent individuals can derive similar benefits as adherent individuals from other risk groups [2]. Nevertheless, coverage of HAART among IDU remains low, not only in areas such as the Russian Federation and other countries of the former Soviet Union and China, where a substantial and increasing proportion of new infections are linked to injection drug use, but also in settings with advanced healthcare systems [3]. Once on HAART, HIVseropositive IDU often achieve lower levels of adherence and are more likely to prematurely discontinue therapy [4,5]. As a result of the individual and, likely, community [6] benefits of attracting and maintaining IDU on HAART, there is an urgent need to identify and remove barriers to access and adherence to HAART among IDU [7].
刑事司法系统中的艾滋病毒治疗
高效抗逆转录病毒疗法的出现使得获得HIV治疗的人群中与HIV相关的发病率和死亡率显著下降[1]。幸运的是,简化治疗方案和扩大治疗系统的努力已经使参与治疗的个人数量和地点达到了10年前无法想象的水平。尽管如此,一些血清阳性人群并没有从艾滋病毒治疗的进步中平等受益。对在HAART治疗中使用注射药物(IDU)的hiv血清阳性个体的研究证实,坚持治疗的个体可以获得与其他风险群体中坚持治疗的个体相似的益处[2]。然而,在IDU中,HAART的覆盖率仍然很低,不仅在俄罗斯联邦和前苏联其他国家和中国等地区,新感染的大量增加比例与注射吸毒有关,而且在具有先进卫生保健系统的环境中也是如此[3]。一旦接受HAART治疗,hiv血清阳性IDU的依从性往往较低,并且更有可能过早停止治疗[4,5]。由于吸引和维持注射吸毒者接受HAART治疗对个人和社区[6]都有好处,因此迫切需要确定并消除注射吸毒者获得和坚持HAART治疗的障碍[7]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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