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Mineralogical composition of the Santonian deposits of the North Konimekh deposit in Uzbekistan 乌兹别克斯坦Konimekh北部矿床三东期矿床的矿物组成
BIO Web of Conferences Pub Date : 2023-01-01 DOI: 10.1051/bioconf/20236509005
Isomiddin Togaev, Doston Buriboyev, Shoxrux Toshtemirov, Baxtinur Abdujabborov
{"title":"Mineralogical composition of the Santonian deposits of the North Konimekh deposit in Uzbekistan","authors":"Isomiddin Togaev, Doston Buriboyev, Shoxrux Toshtemirov, Baxtinur Abdujabborov","doi":"10.1051/bioconf/20236509005","DOIUrl":"https://doi.org/10.1051/bioconf/20236509005","url":null,"abstract":"The article presents information about the results of studying the material composition, mineralogy and geochemistry of deposits formed in the Upper Cretaceous (K2) Santon strata of the North Konimekh uranium deposit located in the Kyzylkum region. Prospecting, appraisal and exploration at the North Konimekh uranium mine is an urgent problem, as it is in the focus of attention of many researchers. This article provides extensive information on underground alkalization, one of the methods for extracting uranium raw materials. Currently, it is emphasized that this method is convenient, has high financial efficiency in the extraction of uranium raw materials, and is also one of the cheapest and most effective methods.","PeriodicalId":8805,"journal":{"name":"BIO Web of Conferences","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77251356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Exogenous Spermine on Biofilm Formation in Mycobacteria by Stimulating the Synthesis of Glycopeptidolipids 外源精胺通过刺激糖肽脂合成对分枝杆菌生物膜形成的影响
BIO Web of Conferences Pub Date : 2023-01-01 DOI: 10.1051/bioconf/20235702002
I. Tsyganov, А.G. Tkachenko
{"title":"Effect of Exogenous Spermine on Biofilm Formation in Mycobacteria by Stimulating the Synthesis of Glycopeptidolipids","authors":"I. Tsyganov, А.G. Tkachenko","doi":"10.1051/bioconf/20235702002","DOIUrl":"https://doi.org/10.1051/bioconf/20235702002","url":null,"abstract":"Biofilm formation is of great interest by its ability to increase bacterial tolerance to antibiotics that represent a serious problem for modern medicine. Among mycobacteria, which are also capable of forming biofilms, there are pathogens of socially dangerous infections, including tuberculosis. Basing on these data, the strains of Mycolicibacterium smegmatis mc2 155 were chosen as the objects of this study, including the parent strain without deletions and its mutants with one (ΔrelMsm) and double (ΔrelMsmΔrelZ) chromosomal deletions of the genes responsible for the synthesis of alarmone synthetase enzymes. Biofilms of mutant strains exhibited defects in biofilm formation. We have shown that the integrity, hydrophobicity, and the level of biomass of surface mycobacterial biofilms are dependent on the amount of glycopeptidolipids (GPL) in cells. The level of GPL depends on the activity of alarmone synthetases. The biogenic polyamine spermine is able to enhance the production of GPLs, restoring the integrity of biofilms of mutant strains. It is possible that this effect of spermine is caused by the influence on the activity of mycobacterial alarmone synthetases, which makes promising the further studying the molecular mechanisms of its action.","PeriodicalId":8805,"journal":{"name":"BIO Web of Conferences","volume":"119 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75009413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physicochemical, Antibacterial, and Cytotoxic Properties of Composite Materials Based on Biodegradable Poly (Lactic-Co-Glycolic Acid) Functionalized with Zno Nanoparticles 纳米氧化锌功能化可生物降解聚乳酸-羟基乙酸复合材料的理化、抗菌和细胞毒性研究
BIO Web of Conferences Pub Date : 2023-01-01 DOI: 10.1051/bioconf/20235702005
D. Burmistrov, D. Serov, D. Grigorieva, A. Simakin
{"title":"Physicochemical, Antibacterial, and Cytotoxic Properties of Composite Materials Based on Biodegradable Poly (Lactic-Co-Glycolic Acid) Functionalized with Zno Nanoparticles","authors":"D. Burmistrov, D. Serov, D. Grigorieva, A. Simakin","doi":"10.1051/bioconf/20235702005","DOIUrl":"https://doi.org/10.1051/bioconf/20235702005","url":null,"abstract":"One of the tasks of modern nanotechnology is the creation of new materials with a wide range of applications and good antibacterial activity. In this work, we developed a new composite material based on poly(lactic-co-glycolic acid) and zinc oxide nanoparticles. The resulting material had a smooth surface without microdefects. The polymer matrix did not affect the generation of reactive oxygen species, 8-oxoguanine, and long-lived protein forms. The addition of ZnO-NPs enhanced the generation of these compounds. The addition of ZnO-NPs to the polymer at a concentration of 0.001-0.1 wt% made it possible to achieve a significant bacteriostatic effect, while not affecting the growth, division, and viability of eukaryotic cells. The resulting composite material is of great interest for biomedical use and the food industry due to controlled biodegradability and antibacterial activity.","PeriodicalId":8805,"journal":{"name":"BIO Web of Conferences","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75079741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioecology of russet mites in tomatoes and their control 番茄褐螨的生物生态学及其防治
BIO Web of Conferences Pub Date : 2023-01-01 DOI: 10.1051/bioconf/20236501019
Abdusalim Yusupov, Dilnoza Nuralieva, Asamiddin Kholliev
{"title":"Bioecology of russet mites in tomatoes and their control","authors":"Abdusalim Yusupov, Dilnoza Nuralieva, Asamiddin Kholliev","doi":"10.1051/bioconf/20236501019","DOIUrl":"https://doi.org/10.1051/bioconf/20236501019","url":null,"abstract":"Tomato russet mite develops freely and quickly mainly on tomatoes and potatoes. The next places are occupied by black and red nightshades and eggplant. The mite can press both the upper and lower sides of the plant leaves. First, the lower leaves and branches of the plant begin to be damaged. It gradually spreads upwards. The affected branch becomes smooth with a brown color, yellow spots appear on the leaves, and the general color begins to turn brown. Infected flowers and small fruit buds and leaves dry up and fall off, large fruits have a web-like pattern and crack. In this article, the species composition, distribution, damage to plants and bioecology of the pest are covered in this article. The development characteristics of the russet mite by plant are presented, in which tomato, potato, and eggplant plants are the most common tomato russet mite in the analysis based on the table. In addition, the results of the research on the effect of the tomato russet mite on productivity in different growth periods are highlighted.","PeriodicalId":8805,"journal":{"name":"BIO Web of Conferences","volume":"184 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72685534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Agronomic assessment of the herbicides application on winter wheat crops 冬小麦除草剂施用的农艺评价
BIO Web of Conferences Pub Date : 2023-01-01 DOI: 10.1051/bioconf/20236604004
O. Savoskina, S. Chebanenko, I. Zavertkin, A. Shitikova, S. Zapivalov
{"title":"Agronomic assessment of the herbicides application on winter wheat crops","authors":"O. Savoskina, S. Chebanenko, I. Zavertkin, A. Shitikova, S. Zapivalov","doi":"10.1051/bioconf/20236604004","DOIUrl":"https://doi.org/10.1051/bioconf/20236604004","url":null,"abstract":"In modern conditions of agricultural production, it is important to obtain a high yield of good quality, which may be limited by a high degree of contamination of crops. At the same time, it is necessary to search for new approaches to the weed control problem, which involves solving a number of issues: determining and analyzing the floral composition of weeds with constant monitoring of contamination to make forecasts and make operational decisions. This work is devoted to the study of these issues. It reveals the features of winter wheat agrophytocenosis formation with the analysis of weed species composition, and shows the effectiveness of the use of herbicides recommended on the basis of mapping. The biological efficiency of the spray mixture of herbicides Verdict + Dinat was 84.1% (by the number of weeds) and 94.9% (by air-dry weight). The agronomic effectiveness of herbicides was expressed in obtaining an increase in yield of 2.67 t/ha, and the profitability level was above the threshold of economic feasibility of the weed management and amounted to 141.8%.","PeriodicalId":8805,"journal":{"name":"BIO Web of Conferences","volume":"155 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77475837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic Composition and Analysis of the Biomorph of Medicinal Plants in the Flora of the Chechen Republic 车臣共和国植物区系药用植物的系统组成及生物形态分析
BIO Web of Conferences Pub Date : 2023-01-01 DOI: 10.1051/bioconf/20236306005
Z. Iriskhanova, H. R. Hanaeva, Sh. M. Bakasheva
{"title":"Systematic Composition and Analysis of the Biomorph of Medicinal Plants in the Flora of the Chechen Republic","authors":"Z. Iriskhanova, H. R. Hanaeva, Sh. M. Bakasheva","doi":"10.1051/bioconf/20236306005","DOIUrl":"https://doi.org/10.1051/bioconf/20236306005","url":null,"abstract":"It was extremely difficult for the deported peoples to adapt to new natural conditions, and to a new ethnic environment, and to a new humiliating situation. K.D. Ushinsky wrote that the influence of natural conditions on people is so powerful that the destruction of these conditions (and in this case separation) torments a person with painful homesickness. A number of government regulations established a cruel special regime. Settlers scattered in small groups from Kyrgyzstan to Kazakhstan did not have the opportunity to keep in touch with each other. In order to survive physically and morally, the settlers had to prove their innocence every minute of their existence. Adaptation in new geographic and climatic conditions, different from historical ones, had a dominating and depressing effect on the moral and psychological state of people.","PeriodicalId":8805,"journal":{"name":"BIO Web of Conferences","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80151503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stability and Bifurcation of Tumor Immune Model with Time Delay 具有时滞的肿瘤免疫模型的稳定性和分岔
BIO Web of Conferences Pub Date : 2023-01-01 DOI: 10.1051/bioconf/20235902017
Li Yangjuan, Xiao Zhengying, Lin Jinzhong
{"title":"Stability and Bifurcation of Tumor Immune Model with Time Delay","authors":"Li Yangjuan, Xiao Zhengying, Lin Jinzhong","doi":"10.1051/bioconf/20235902017","DOIUrl":"https://doi.org/10.1051/bioconf/20235902017","url":null,"abstract":"In this paper, we investigate the effect of time delay on the stability of the tumor immune system using theoretical calculations and numerical simulations. Since it takes a certain time for immune cells to recognize tumor cells to make an appropriate response, a model of tumor-immune system interaction with time delay is established by considering time delay in this process. The four equilibrium points are solved by simplifying the model using Taylor expansion with a small time delay. Then the stability of each equilibrium point of the system under a small time delay is determined by calculating the characteristic roots of each equilibrium point with numerical simulation software. The results show that the system has a bistability phenomenon. The saddle point and stable node are not affected by the delay, while only the stability of the stable foci changes with the time delay with Hopf bifurcation. This study can help determine the optimal time for tumor treatment and provide a reference for analyzing tumor status and treatment.","PeriodicalId":8805,"journal":{"name":"BIO Web of Conferences","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80280490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stimulus-responsive tumor supramolecular nanotherapeutic system based on indocyanine green 基于吲哚菁绿的刺激反应性肿瘤超分子纳米治疗系统
BIO Web of Conferences Pub Date : 2023-01-01 DOI: 10.1051/bioconf/20236101003
Wenbi Feng, Yuhan Wei, Xianfeng Zhou
{"title":"Stimulus-responsive tumor supramolecular nanotherapeutic system based on indocyanine green","authors":"Wenbi Feng, Yuhan Wei, Xianfeng Zhou","doi":"10.1051/bioconf/20236101003","DOIUrl":"https://doi.org/10.1051/bioconf/20236101003","url":null,"abstract":"Indocyanine green (ICG), a clinical near-infrared fluorescent probe, has the potential to be used as an integrated diagnostic and therapeutic agent for tumors. In this study, ICG-COOH-TK was obtained by connecting ICG molecules through stimulus-responsive thioketone (TK) bond, which can self-assemble into nanoparticles in water. Under 808 nm near-infrared light irradiation, the molecule exhibited excellent photothermal conversion efficiency, as well as better photostability and in vivo circulation stability than free ICG. The nanoparticle can respond to reactive oxygen species (ROS) overexpression in the tumor microenvironment and release ICG upon disassembly, resulting in significantly enhanced fluorescence emission at the tumor. In vitro cell experiments demonstrated excellent biocompatibility and photothermal killing effect on cancer cells, indicating that this molecule can serve as a diagnostic and therapeutic agent for fluorescence-guided tumor photothermal therapy.","PeriodicalId":8805,"journal":{"name":"BIO Web of Conferences","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81639067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tactics of surgical treatment in necrotising enterocolitis stage II-B in newborn 新生儿坏死性小肠结肠炎II-B期的外科治疗策略
BIO Web of Conferences Pub Date : 2023-01-01 DOI: 10.1051/bioconf/20236505005
A. Vakhidov, D. Mamarasulova, Akmal Khaitov
{"title":"Tactics of surgical treatment in necrotising enterocolitis stage II-B in newborn","authors":"A. Vakhidov, D. Mamarasulova, Akmal Khaitov","doi":"10.1051/bioconf/20236505005","DOIUrl":"https://doi.org/10.1051/bioconf/20236505005","url":null,"abstract":"An analysis was made of the results of surgical treatment of 18 newborns with a diagnosis of stage II-B NEC, admitted in the period from 2018 to 2022. The aim of the work: to analyze the results of surgical treatment for stage II-B necrotizing enterocolitis in newborns using modern technologies. A total of 18 diagnostic laparoscopies (DL) were performed, of which 4 cases were converted - laparotomy. In 14 patients cases, DL was completed by therapeutic laparoscopy using minilaparotomy with video-assessment, including 8 patients, resection of the necrotic portion of the intestine was performed with end-to-end anastomosis. In 6 cases, an intestinal stoma was applied through a minilaparotomy.In comparison, after laparoscopic operations with video assessment, mortality was observed of cases 1 patient out of 14, after traditional surgical interventions, mortality was in 25% of cases 1 patient out of 4. Based on the results of DL at the surgical stage of NEC, it is possible to build further tactics of radical surgical treatment, the possibility of transforming it into a therapeutic one minimizes intraoperative trauma, which positively affects the postoperative survival of patients.","PeriodicalId":8805,"journal":{"name":"BIO Web of Conferences","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84252058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of foliar biostimulants (of plant origin) on grapevine adaptation to climate change 叶面生物刺激素(植物源)在葡萄适应气候变化中的作用
BIO Web of Conferences Pub Date : 2023-01-01 DOI: 10.1051/bioconf/20235601002
L. Bavaresco, Ginevra Canavera, M. G. Parisi, L. Lucini
{"title":"Role of foliar biostimulants (of plant origin) on grapevine adaptation to climate change","authors":"L. Bavaresco, Ginevra Canavera, M. G. Parisi, L. Lucini","doi":"10.1051/bioconf/20235601002","DOIUrl":"https://doi.org/10.1051/bioconf/20235601002","url":null,"abstract":"Heat waves and drought stress are typical aspects of current climate change, significantly affecting the grapevine physiology in many world growing areas. Biostimulants can play an important role in reducing the negative effects of climate change; that’s why this experiment was set up in order to test two new foliar biostimulants (protein hydrolysates of plant origin). The field experiment was carried out in 2017 and 2018 in Oltrepo pavese area (Lombardia region, northwest Italy, 270 m asl), on a six-year-old vineyard of V. vinifera L. cv. Merlot clone 181 grafted on Gravesac, Guyot trellis, 4,000 vines/ha and not irrigated. Two new protein hydrolysates of plant origin were sprayed twice, just after fruit set and 15 days later, by using 2.5 L/ha. Leaf proteomics and metabolomics were studied in 2017, while productive and qualitative data were recorded in both years at harvest (September 1st, 2017 and August 28th 2018). The most significant findings were: (a) the treatments slowed down the grape ripening, by stimulating vegetative activity and reducing sugar accumulation; (b) less heat and drought stress symptoms were observed in the canopies of treated vines, as compared to the control ones.","PeriodicalId":8805,"journal":{"name":"BIO Web of Conferences","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85090552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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