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COVID-19 and Intensive Care Unit Resource Allocation COVID-19和重症监护病房资源分配
University of Western Ontario medical journal Pub Date : 2022-01-27 DOI: 10.5206/uwomj.v89is1.10656
Ziad Sabaa-Ayoun
{"title":"COVID-19 and Intensive Care Unit Resource Allocation","authors":"Ziad Sabaa-Ayoun","doi":"10.5206/uwomj.v89is1.10656","DOIUrl":"https://doi.org/10.5206/uwomj.v89is1.10656","url":null,"abstract":"","PeriodicalId":87852,"journal":{"name":"University of Western Ontario medical journal","volume":"121 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81358610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Schulich students for emergency childcare: Results of a community initiative during COVID-19 舒立克学生紧急托儿:COVID-19期间社区倡议的结果
University of Western Ontario medical journal Pub Date : 2021-11-05 DOI: 10.5206/uwomj.v89is1.10898
Chris Zhang, Nadeesha Samarasinghe, Jessica R. Garabon, G. Katznelson, Montana Hackett, Yashoda Valliere, Rebecca Barnfield
{"title":"Schulich students for emergency childcare: Results of a community initiative during COVID-19","authors":"Chris Zhang, Nadeesha Samarasinghe, Jessica R. Garabon, G. Katznelson, Montana Hackett, Yashoda Valliere, Rebecca Barnfield","doi":"10.5206/uwomj.v89is1.10898","DOIUrl":"https://doi.org/10.5206/uwomj.v89is1.10898","url":null,"abstract":"The coronavirus disease (COVID-19) pandemic led to the abrupt suspension of many businesses and services in Ontario including schools and childcare centres. This resulted in many parents struggling to identify options for childcare, including frontline healthcare workers (HCWs). A volunteer initiative composed of medical and dental students was developed to provide emergency childcare support to HCWs in Southwestern Ontario. Experts in areas of public health, law, and bioethics were consulted to minimize the risks associated with participation and develop a clear policy to prioritize the health and safety of all participants. Social media was utilized to recruit volunteers and HCWs who were matched on a first-come, first-served basis. 59 medical and dental students were recruited to provide emergency support for 21 HCWs within the unique safety and ethical conditions posed by COVID-19. By reflecting on the strengths of this initiative and the challenges faced during its completion, key areas of improvement were identified that should be addressed in future initiatives of a similar nature.","PeriodicalId":87852,"journal":{"name":"University of Western Ontario medical journal","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82103726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of fear in emergency medicine 恐惧对急诊医学的影响
University of Western Ontario medical journal Pub Date : 2021-06-01 DOI: 10.5206/uwomj.v89i2.14361
David Zheng
{"title":"The influence of fear in emergency medicine","authors":"David Zheng","doi":"10.5206/uwomj.v89i2.14361","DOIUrl":"https://doi.org/10.5206/uwomj.v89i2.14361","url":null,"abstract":"","PeriodicalId":87852,"journal":{"name":"University of Western Ontario medical journal","volume":"124 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83519652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
It’s All in the Details 一切都在细节中
University of Western Ontario medical journal Pub Date : 2021-02-21 DOI: 10.5206/UWOMJ.V89I1.8589
Anastasiya Vinokurtseva, A. Kassay
{"title":"It’s All in the Details","authors":"Anastasiya Vinokurtseva, A. Kassay","doi":"10.5206/UWOMJ.V89I1.8589","DOIUrl":"https://doi.org/10.5206/UWOMJ.V89I1.8589","url":null,"abstract":"Cancer is estimated to affects around half of Canadian population in their lifetime. Often a fatal disease, it costs billions to Canadian healthcare system yearly. Cancer diagnosis, and subsequent prognosis and treatment, all require characterization of tumor cell morphology and genotype, which is conventionally done using invasive biopsy methods. However, less invasive modalities exist and include liquid biopsy – sampling of body fluids for cancer cells and cellular material. It is less invasive compared to majority of conventional practices and yields a variety of biomarkers for further laboratory analysis. Analytical techniques including aptamers – a synthetic analogue to antibodies with increased affinity to target, allow for robust analysis of molecular data. This article discusses directions of research and current applications of these innovations and implications to diagnosis in clinical practice.","PeriodicalId":87852,"journal":{"name":"University of Western Ontario medical journal","volume":"131 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89873044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The case for and against selective serotonin reuptake inhibitors in rapid cycling bipolar disorder 选择性5 -羟色胺再摄取抑制剂在快速循环双相情感障碍中的作用
University of Western Ontario medical journal Pub Date : 2021-01-23 DOI: 10.5206/UWOMJ.V89I1.8588
D. Semenov, Jason Quinn
{"title":"The case for and against selective serotonin reuptake inhibitors in rapid cycling bipolar disorder","authors":"D. Semenov, Jason Quinn","doi":"10.5206/UWOMJ.V89I1.8588","DOIUrl":"https://doi.org/10.5206/UWOMJ.V89I1.8588","url":null,"abstract":"Patients affected by the rapid cycling variant of bipolar disorder often experience significant functional difficulties. Physicians caring for affected patients face many challenges managing the turbulent course of this disorder, complicated at times by psychiatric comorbidities (including substance use disorders), polypharmacy, risk management (of suicidality and aggression), and difficulties with community functioning. There is some controversy about the use of selective serotonin receptor inhibitors (SSRIs) in managing bipolar depression, particularly in the rapid cycling variant. The potential benefit of SSRIs in reducing depressive symptoms must be balanced against the risks of mood phase switching and overall worsening of the rapid cycling course. This case report highlights challenges inherent in the application of SSRIs in a case of treatment-refractory rapid cycling bipolar disorder, and discusses the controversy of their use.","PeriodicalId":87852,"journal":{"name":"University of Western Ontario medical journal","volume":"283 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77545021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of the COVID-19 response in Uganda: “HIV-associated morbidity and mortality stands in the balance" COVID-19应对措施对乌干达的影响:“与艾滋病毒相关的发病率和死亡率悬而未决”
University of Western Ontario medical journal Pub Date : 2020-11-08 DOI: 10.5206/uwomj.v89is1.10927
Avalon O’Connor, C. Leung, Sun-Ok Jung, Danit Freedman, Amanda Stojcevski
{"title":"Impact of the COVID-19 response in Uganda: “HIV-associated morbidity and mortality stands in the balance\"","authors":"Avalon O’Connor, C. Leung, Sun-Ok Jung, Danit Freedman, Amanda Stojcevski","doi":"10.5206/uwomj.v89is1.10927","DOIUrl":"https://doi.org/10.5206/uwomj.v89is1.10927","url":null,"abstract":"","PeriodicalId":87852,"journal":{"name":"University of Western Ontario medical journal","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88815067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating Naturopathic Remedies in Oncology 肿瘤学中的自然疗法导航
University of Western Ontario medical journal Pub Date : 2020-10-11 DOI: 10.5206/uwomj.v89i1.8571
Nafis Hossain, Mary Nguyen
{"title":"Navigating Naturopathic Remedies in Oncology","authors":"Nafis Hossain, Mary Nguyen","doi":"10.5206/uwomj.v89i1.8571","DOIUrl":"https://doi.org/10.5206/uwomj.v89i1.8571","url":null,"abstract":"The use of naturopathic and other alternative forms of cancer treatment are pervasive, and many patients may firmly believe in their effectiveness. This can present headwinds for physicians who have been trained to incorporate evidence-based practices into their care. This underscores the need for health care providers to be cognizant of the impact of these alternative therapies; it is imperative to understand patient perspectives regarding their use and find middle ground where it exists. We had the opportunity to speak with Dr. David Palma, who is a radiation oncologist and clinician-scientist at the London Health Sciences Centre who has had a vested interest in improving patient access to quality cancer treatment. In this article, Dr. Palma discusses his thoughts about the rising trend of alternative cancer treatments, and how we as future physicians can reconcile with their growing influence.","PeriodicalId":87852,"journal":{"name":"University of Western Ontario medical journal","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78187692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cell-free DNA 游离DNA
University of Western Ontario medical journal Pub Date : 2020-08-24 DOI: 10.5206/uwomj.v88is.8169
E. Pickering
{"title":"Cell-free DNA","authors":"E. Pickering","doi":"10.5206/uwomj.v88is.8169","DOIUrl":"https://doi.org/10.5206/uwomj.v88is.8169","url":null,"abstract":"Chromosomal disorders arise from errors in cell division and many are detected during prenatal development. Prenatal genomic screening techniques involve invasive methods such as chorionic villus sampling and amniocentesis. In this feature, current invasive techniques for genetic screening will be examined in relation to the development of non-invasive prenatal technology. As cell-free fetal DNA methods continue to develop and be integrated into clinical practice, there is an opportunity for improvement in the detection and reliability of the screening process. In clinic, there are disparities between clinicians and patients surrounding both understanding of the processes and the discussion on the technique limitations. Non-invasive methods are continually being improved for detecting genetic disorders through the use of cell-free fetal DNA, and with these advancements, these processes will become safe, cost-effective, and reliable for pregnant mothers when undergoing genetic screening and counselling.","PeriodicalId":87852,"journal":{"name":"University of Western Ontario medical journal","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90830458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cover Art 封面
University of Western Ontario medical journal Pub Date : 2020-08-21 DOI: 10.5206/uwomj.v88i2.10984
Kara M. Ruicci
{"title":"Cover Art","authors":"Kara M. Ruicci","doi":"10.5206/uwomj.v88i2.10984","DOIUrl":"https://doi.org/10.5206/uwomj.v88i2.10984","url":null,"abstract":"‘Mental Health’ encompasses our cognitive, behavioural and emotional wellbeing; disorders of mental health affect mood, thinking and behaviour. To this day, mental health disorders are feared and stigmatized because these conditions are not overtly visible. The way forward in continuing to dissipate the stigma associated with mental health disorders is to recognize, diagnose and treat these conditions—just as we do for any other ailment of the body. Here, a stethoscope representing medical care is shown surrounding the profile of a human face. Inside, a brain is seen; if you look closely, you will see that its shape is comprised by lines forming a fingerprint. The fingerprint signifies the wide range of mental health conditions and their unique manifestations between individuals. Continued advancements in both research and the clinical management of mental health conditions will improve patient care and help continue to dispel stigma.","PeriodicalId":87852,"journal":{"name":"University of Western Ontario medical journal","volume":"50 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73054766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From madness to mental illness 从疯狂到精神疾病
University of Western Ontario medical journal Pub Date : 2020-06-30 DOI: 10.5206/uwomj.v88i2.7593
R. Hudson
{"title":"From madness to mental illness","authors":"R. Hudson","doi":"10.5206/uwomj.v88i2.7593","DOIUrl":"https://doi.org/10.5206/uwomj.v88i2.7593","url":null,"abstract":"Reports of psychotic episodes characterized by irrational, unintelligible behaviours and hallucinations are frequent throughout historical narratives. Appropriately contextualized, some of these descriptions appear to resemble the paranoid, and catatonic characteristics of schizophrenia, respectively, yet holistic accounts of schizophrenia-like syndromes rarely exist prior to the 19th century.1 Despite evolving diagnostic criteria and treatment approaches, and more than 100 years since the demarcation of schizophrenia by Eugen Bleuler in 1908, the etiology, neuropathology and pathophysiology of schizophrenia remain elusive.2-4 No biological markers possess the sensitivity and specificity expected of a diagnostic test, and schizophrenia persists conceptually as a broad clinical syndrome characterized by a range of subjective symptoms with varying patterns of course.5-8 This heterogeneity coupled with a lack of coherence between clinical and preclinical evidence have fueled speculation about the validity of current conceptualizations of the illness.9-12 Nevertheless, patients exhibit typical symptom progression over time, appear to respond favourably to particular treatment approaches, and despite inconsistencies in diagnostic classification, alternative proposals do not offer improvements in any of these categories.13,14 Undoubtedly, further parsing of schizophrenia and related disorders will be necessary to advance future treatment and diagnostic approaches. In this review, we briefly outline the origins of schizophrenia as it is conceptualized contemporarily by linking ancient medical descriptions with modern clinical perspectives, and discuss why historical accounts of schizophrenia may not accurately reflect its prevalence in the past.","PeriodicalId":87852,"journal":{"name":"University of Western Ontario medical journal","volume":"34 5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83605617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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