{"title":"Abstracts to additional papers presented at the symposium honoring Dr. Samuel P. Bessman.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8781,"journal":{"name":"Biochemical medicine","volume":"33 2","pages":"271-8"},"PeriodicalIF":0.0,"publicationDate":"1985-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15117537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Developmental aspects of mitochondrial creatine kinase in rat myocardial cell cultures","authors":"","doi":"10.1016/0006-2944(85)90050-X","DOIUrl":"https://doi.org/10.1016/0006-2944(85)90050-X","url":null,"abstract":"","PeriodicalId":8781,"journal":{"name":"Biochemical medicine","volume":"33 2","pages":"Page 276"},"PeriodicalIF":0.0,"publicationDate":"1985-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0006-2944(85)90050-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72206294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anabolic response of some tissues to diabetes","authors":"","doi":"10.1016/0006-2944(85)90037-7","DOIUrl":"https://doi.org/10.1016/0006-2944(85)90037-7","url":null,"abstract":"","PeriodicalId":8781,"journal":{"name":"Biochemical medicine","volume":"33 2","pages":"Pages 271-272"},"PeriodicalIF":0.0,"publicationDate":"1985-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0006-2944(85)90037-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137366608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The regulation of mitochondrial-bound hexokinases in the liver","authors":"U. Weiler, I. Riesinger, G. Knoll, D. Brdiczka","doi":"10.1016/0006-2944(85)90031-6","DOIUrl":"10.1016/0006-2944(85)90031-6","url":null,"abstract":"<div><p>A functional coupling between bound hexokinase and the inner mitochondrial compartment has been shown. It is based structurally on the binding of hexokinase to a pore protein which is present in zones of contact between the two boundary membranes. The latter was observed by electron microscopic localization of antiporin and hexokinase at the mitochondrial surface.</p><p>The four isoenzymes present in liver differ considerably in their activity after binding to the mitochondrial surface. This was found by binding studies using the four isoenzymes isolated from the supernatant. Isoenzyme IV did not bind at all. Isoenzymes I–III did bind and became activated: I, 5.9-fold; II, 39-fold; and III, 1.3-fold. These results suggest that the <em>in vivo</em> activity of hexokinase in the mitochondrial fraction is much larger than so far observed.</p><p>Furthermore the binding of isoenzymes was differently affected by metabolites. Glucose 6-phosphate exclusively desorbed isoenzyme I from the mitochondrial membrane whereas free fatty acids predominantly liberated isoenzymes II and III. A reciprocal change of the levels of free fatty acids and glucose 6-phosphate in livers of starved rats therefore, can explain why exclusively mitochondrial-bound isoenzymes II and III decreased 10-fold while at the same time isoenzyme I increased.</p></div>","PeriodicalId":8781,"journal":{"name":"Biochemical medicine","volume":"33 2","pages":"Pages 223-235"},"PeriodicalIF":0.0,"publicationDate":"1985-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0006-2944(85)90031-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14122085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dr. Samuel P. Bessman.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":8781,"journal":{"name":"Biochemical medicine","volume":"33 2","pages":"133-40"},"PeriodicalIF":0.0,"publicationDate":"1985-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15007244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dissociation of aortic tissue renin and the plasma levels of active and inactive renin in the one- and two-kidney goldblatt hypertensive rat","authors":"","doi":"10.1016/0006-2944(85)90036-5","DOIUrl":"https://doi.org/10.1016/0006-2944(85)90036-5","url":null,"abstract":"","PeriodicalId":8781,"journal":{"name":"Biochemical medicine","volume":"33 2","pages":"Page 271"},"PeriodicalIF":0.0,"publicationDate":"1985-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0006-2944(85)90036-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137366607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M.E. Towell , J. Johnson , I. Lysak , D.F. Sayler , S.P. Bessman
{"title":"Maternal, fetal, and newborn tissue PO2 in sheep measured with galvanic oxygen electrodes","authors":"M.E. Towell , J. Johnson , I. Lysak , D.F. Sayler , S.P. Bessman","doi":"10.1016/0006-2944(85)90026-2","DOIUrl":"10.1016/0006-2944(85)90026-2","url":null,"abstract":"<div><p>Tissue <em>P</em>O<sub>2</sub> was measured with galvanic oxygen electrodes chronically implanted in maternal and fetal tissues of two pregnant ewes. Labor commenced after 3 days in one ewe and after 11 days in the other. Tissue <em>P</em>O<sub>2</sub> was measured in both newborn lambs. Fetal tissue <em>P</em>O<sub>2</sub> during labor was less than 3 mm Hg but rose to values similar to those found in adult tissues in the newborn period. Function of the electrode and response of the tissue to change in oxygenation was challenged by administration of 100% oxygen to the pregnant ewe or newborn lamb, and by administration of intravenous epinephrine to the ewe. These tests suggested that all electrodes were functioning satisfactorily <em>in vivo</em> and that tissue <em>P</em>O<sub>2</sub> was responding as anticipated. Recalibration of electrodes after removal from the tissues confirmed that their response <em>in vitro</em> was similar to that obtained before implantation.</p></div>","PeriodicalId":8781,"journal":{"name":"Biochemical medicine","volume":"33 2","pages":"Pages 180-188"},"PeriodicalIF":0.0,"publicationDate":"1985-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0006-2944(85)90026-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15117531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of stress hormones in the development of hyperglycemia","authors":"","doi":"10.1016/0006-2944(85)90052-3","DOIUrl":"https://doi.org/10.1016/0006-2944(85)90052-3","url":null,"abstract":"","PeriodicalId":8781,"journal":{"name":"Biochemical medicine","volume":"33 2","pages":"Page 277"},"PeriodicalIF":0.0,"publicationDate":"1985-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0006-2944(85)90052-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72256370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of insulin on high-energy nucleotides, glycolytic intermediates, and the Krebs cycle in isolated rat hepatocytes","authors":"","doi":"10.1016/0006-2944(85)90053-5","DOIUrl":"https://doi.org/10.1016/0006-2944(85)90053-5","url":null,"abstract":"","PeriodicalId":8781,"journal":{"name":"Biochemical medicine","volume":"33 2","pages":"Pages 277-278"},"PeriodicalIF":0.0,"publicationDate":"1985-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0006-2944(85)90053-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72256400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}