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Tuna Can Harbor Histamine-Producing Bacteria 金枪鱼能滋生产生组胺的细菌
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/microbe.11.192.1
D. Holzman
{"title":"Tuna Can Harbor Histamine-Producing Bacteria","authors":"D. Holzman","doi":"10.1128/microbe.11.192.1","DOIUrl":"https://doi.org/10.1128/microbe.11.192.1","url":null,"abstract":"Tuna fish may carry bacteria that, even at lowered temperatures, grow and retain histidine decarboxylase (HDC) enzyme activity, raising questions about the potential for those enzymes producing histamines in refrigerated fresh tuna, according to Kristin Bjornsdottir-Butler, of the Gulf Coast Seafood Laboratory, a Food and Drug Administration research facility on Dauphin Island, Ala., and her collaborators. These cold-tolerant, histamine-producing bacteria are indigenous to the fish, not contaminants introduced during handling, the researchers note. Details appeared 29 January 2016 in Applied and Environmental Microbiology (doi:10.1128/AEM.02833–15/).","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":"11 1","pages":"192-193"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63639377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibiotic Resistance Spreads through Diverse Species and Habitats, Part I: The public health threat amplifies as drug-resistant pathogens move freely through various environments and species 抗生素耐药性通过不同的物种和栖息地传播，第一部分:随着耐药病原体在各种环境和物种中自由移动，公共卫生威胁扩大
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/MICROBE.11.201.1
Shannon Weiman
{"title":"Antibiotic Resistance Spreads through Diverse Species and Habitats, Part I: The public health threat amplifies as drug-resistant pathogens move freely through various environments and species","authors":"Shannon Weiman","doi":"10.1128/MICROBE.11.201.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.201.1","url":null,"abstract":"Antibiotic-resistant bacteria continue to spread across the globe—directly affecting human and animal patients while also establishing reservoirs from which those strains continue to emerge long into the future, according to several researchers who spoke during the 2015 ICAAC conference held in San Diego last September. Their findings paint a broader and, in some ways, more alarming picture of the expanding influence and dynamic nature of antibiotic resistance than experts previously drew.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":"11 1","pages":"201-207"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63639407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbe Mentor:Career Activities at ASM Microbe 2016 微生物导师:ASM微生物2016的职业活动
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/MICROBE.11.223.1
L. Runyen-Janecky
{"title":"Microbe Mentor:Career Activities at ASM Microbe 2016","authors":"L. Runyen-Janecky","doi":"10.1128/MICROBE.11.223.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.223.1","url":null,"abstract":"In our second edition of a two-part series about Microbe 2016, we invited Dr. Laura Runyen-Janecky, Professor in the Department of Biology at the University of Richmond, to provide insight on how students and postdocs can navigate the careers activities at Microbe 2016. Here is what she had to say:","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":"11 1","pages":"223-225"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63639599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Postdoc Life 博士后生活
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/microbe.11.189.1
Cara McDonough
{"title":"The Postdoc Life","authors":"Cara McDonough","doi":"10.1128/microbe.11.189.1","DOIUrl":"https://doi.org/10.1128/microbe.11.189.1","url":null,"abstract":"I am not a scientist. But I've observed a scientist's life—including late-night time points and stress over preliminary exams—since I first started dating my now-husband when he was a Ph.D. candidate at the University of North Carolina.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":"11 1","pages":"189-189"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63639038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infecting Pregnant Mice Disrupts Fetal Brain, Inducing Autism 感染怀孕小鼠扰乱胎儿大脑，诱发自闭症
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/MICROBE.11.194.1
Shannon Weiman
{"title":"Infecting Pregnant Mice Disrupts Fetal Brain, Inducing Autism","authors":"Shannon Weiman","doi":"10.1128/MICROBE.11.194.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.194.1","url":null,"abstract":"Infecting pregnant mice can activate immune responses that disrupt fetal brain development, causing autism spectrum disorder (ASD)-like syndrome in newborn mice, according to Gloria Choi of Massachusetts Institute of Technology in Cambridge, Mass., and her collaborators there and at several other institutions. The inflammatory cytokine IL-17a orchestrates that pathology, a finding with implications for preventive and therapeutic strategies if the mechanism in mice applies to humans, they say. Details appeared online 28 January 2016 in Science (doi: 10.1126/science.aad0314).","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":"11 1","pages":"194-195"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63639094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reviews and Resources:Metabolism and Bacterial Pathogenesis: BOOKS 综述和资源:代谢和细菌发病机制:图书
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/MICROBE.11.227.2
G. Mora
{"title":"Reviews and Resources:Metabolism and Bacterial Pathogenesis: BOOKS","authors":"G. Mora","doi":"10.1128/MICROBE.11.227.2","DOIUrl":"https://doi.org/10.1128/MICROBE.11.227.2","url":null,"abstract":"I recently had the pleasure of reading this wonderful book. Metabolism and Bacterial Pathogenesis came at the right time, because I work on a human-exclusive pathogen for which some strains collected from patients are auxotrophic, making me wonder: how is it that a pathogen that is very effective at surviving in humans requires one of the very amino acids that is limiting in humans? Every chapter in this book, directly or indirectly, suggested to me that the answer I am looking for it may be very near, and what I have to do is to dig through some of the numerous references listed. These references are so limited that it made me recall the frequent editorial restrictions on references—clearly, the contributors were encouraged to freely discuss the details in depth. The contributors also suggest provocative and challenging new concepts, e.g. “pathometabolism.” This term encompasses the complex metabolic interactions between host and bacterial pathogen, concepts that could lead to novel antimicrobial therapeutics.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":"11 1","pages":"227-227"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1128/MICROBE.11.227.2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63639709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Setting Sail for the Future: In a fast-moving world, ASM has a big role to play to fulfill its mission of advancing and promoting the microbial sciences 为未来扬帆起航:在一个快速发展的世界中，ASM在实现其推进和促进微生物科学的使命方面发挥着重要作用
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/MICROBE.11.190.1
S. Bertuzzi
{"title":"Setting Sail for the Future: In a fast-moving world, ASM has a big role to play to fulfill its mission of advancing and promoting the microbial sciences","authors":"S. Bertuzzi","doi":"10.1128/MICROBE.11.190.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.190.1","url":null,"abstract":"It was with great excitement that I took the helm of the great ASM schooner as the new Chief Executive Officer at the beginning of January. It has been only a few months, but I would like to share my first impressions and the excitement that I feel.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":"11 1","pages":"190-191"},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1128/MICROBE.11.190.1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63639304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unsettling Case of Colistin-, Carbapenem-Resistant P. aeruginosa in Canada 令人不安的案例粘菌素，碳青霉烯耐铜绿假单胞菌在加拿大
Microbe (Washington, D.C.) Pub Date : 2016-04-01 DOI: 10.1128/MICROBE.11.146.1
D. Holzman
{"title":"Unsettling Case of Colistin-, Carbapenem-Resistant P. aeruginosa in Canada","authors":"D. Holzman","doi":"10.1128/MICROBE.11.146.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.146.1","url":null,"abstract":"The first North American instance of an individual infected with Pseudomonas aeruginosa that is resistant to colistin and also carries the resistance gene NDM-1 was documented last year, according to Johann Pitout of the Cumming School of Medicine at the University of Calgary in Calgary, Alberta, Canada, and his collaborators elsewhere in Canada and in South Africa. Importantly, that isolated case illustrates “the need for appropriate infection prevention and control measures and vigilant screening for carbapenem resistant gram-negative bacteria in patients with a history of travel to endemic areas, such as the Indian subcontinent,” they note. Details of appeared 11 January 2016 in Antimicrobial Agents and Chemotherapy (doi:10.1128/AAC.02591–15).","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":"279 1","pages":"146-148"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63636293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Small Things Considered 考虑到的小事
Microbe (Washington, D.C.) Pub Date : 2016-04-01 DOI: 10.1128/MICROBE.11.186.1
Brandon Kieft
{"title":"Small Things Considered","authors":"Brandon Kieft","doi":"10.1128/MICROBE.11.186.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.186.1","url":null,"abstract":"Though seawater looks uniform to our eyes, it is actually highly heterogeneous, containing vast amounts of microscopic particles, fluctuating chemical and nutri-ent gradients, and 1 billion or so diverse microbial organisms per liter. Turbu-lence, diffusion, thermal mixing, and currents add to the patchiness of ocean water, churning and stirring molecular-sized resources. Near the coastal oceans and in estuaries, especially at higher lati-tudes that have distinct seasons, varying sources of dissolved organic compounds make microgradients even more pro-nounced: during times of high river discharge, a coastal environment can become inundated with resources from washed-out terrestrial matter, often leading to phytoplankton blooms.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":"11 1","pages":"186-186"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1128/MICROBE.11.186.1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63637644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carrying Antimicrobial Candidates across the Valley of Death: Key Milestones: Deciding to continue or when to halt development of seemingly promising antibiotic candidates is an iterative exercise 携带候选抗微生物药物跨越死亡之谷:关键里程碑:决定继续或何时停止看似有希望的候选抗生素的开发是一个反复的练习
Microbe (Washington, D.C.) Pub Date : 2016-04-01 DOI: 10.1128/microbe.11.155.1
J. Fox
{"title":"Carrying Antimicrobial Candidates across the Valley of Death: Key Milestones: Deciding to continue or when to halt development of seemingly promising antibiotic candidates is an iterative exercise","authors":"J. Fox","doi":"10.1128/microbe.11.155.1","DOIUrl":"https://doi.org/10.1128/microbe.11.155.1","url":null,"abstract":"What does a company need to do when a promising antimicrobial drug candidate turns up as part of a concerted research and development (R&D) program? First and foremost, said George Drusano of the University of Florida, Gainesville, “You need a hero to push the molecule forward.” However, if the molecule fails to meet critical milestones during that push forward, no matter how good it looked earlier, he added, “At some point, you need to put ‘old yeller’ down.”","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":"240 1","pages":"155-158"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63636869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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