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Food Sources Harbor Antibiotic-Resistant Pathogens, Part 2: Antibiotic-resistant strains from food reservoirs at the local level can quickly disseminate, leading to worldwide public health risks 食物来源含有耐抗生素病原体，第2部分:来自地方一级食物储存库的耐抗生素菌株可迅速传播，导致全球公共卫生风险
Microbe (Washington, D.C.) Pub Date : 2016-06-01 DOI: 10.1128/MICROBE.11.247.1
Shannon Weiman
{"title":"Food Sources Harbor Antibiotic-Resistant Pathogens, Part 2: Antibiotic-resistant strains from food reservoirs at the local level can quickly disseminate, leading to worldwide public health risks","authors":"Shannon Weiman","doi":"10.1128/MICROBE.11.247.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.247.1","url":null,"abstract":"Some foods serve as important reservoirs of antibiotic-resistant bacteria—from produce to seafood, livestock, and poultry, according to researchers who presented their findings during the 2015 ICAAC held in San Diego last September. These reservoirs expose food workers and consumers to pathogens, including methicillin-resistant Staphylococcus aureus (MRSA), extended-spectrum β-lactamase Escherichia coli (ESBL-E. coli), and carbapenem-resistant Enterobacteriaceae (CRE). All these pathogens may be carried asymptomatically or can cause difficult-to-treat infections, some confined to the gastrointestinal tract, while others cause more invasive disease. Due to blurring of boundaries between local and global markets, local food production practices can lead to regional and even worldwide public health risks when contaminated foods disperse resistant strains to distant locations, experts warn.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1128/MICROBE.11.247.1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63640341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The International Space Station: an Extreme Environment for Key Host-Microbe Discoveries: Microgravity encountered during spaceflight helps to determine how various forces influence microbes as they interact with hosts and environments 国际空间站:关键宿主-微生物发现的极端环境:在太空飞行期间遇到的微重力有助于确定各种力量如何影响微生物与宿主和环境相互作用
Microbe (Washington, D.C.) Pub Date : 2016-06-01 DOI: 10.1128/MICROBE.11.253.1
C. M. Ott, T. Marshburn, C. Nickerson
{"title":"The International Space Station: an Extreme Environment for Key Host-Microbe Discoveries: Microgravity encountered during spaceflight helps to determine how various forces influence microbes as they interact with hosts and environments","authors":"C. M. Ott, T. Marshburn, C. Nickerson","doi":"10.1128/MICROBE.11.253.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.253.1","url":null,"abstract":"Experiments aboard the space station that test how microorganisms function in microgravity add to our understanding of how microorganisms behave in extreme environments. By reducing gravity, which has been a constant force throughout evolution, and exposing microbes to radiation in space, we can improve our understanding of microorganisms on Earth.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1128/MICROBE.11.253.1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63640393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
PCR for Everything—Seeking Value in Speed: With faster and more comprehensive diagnostic tests becoming widely available, we need to think more carefully about whether they truly improve patient care PCR在速度上的价值:随着更快、更全面的诊断测试的广泛应用，我们需要更仔细地思考它们是否真正改善了病人的护理
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/MICROBE.11.209.1
B. Lopansri
{"title":"PCR for Everything—Seeking Value in Speed: With faster and more comprehensive diagnostic tests becoming widely available, we need to think more carefully about whether they truly improve patient care","authors":"B. Lopansri","doi":"10.1128/MICROBE.11.209.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.209.1","url":null,"abstract":"In the summer of 2013, a patient arrived in our emergency department with complaints of high fever and abdominal pain. She came to us straight from the airport following her return from a 3-month visit to India. Identified as septic, she was “pan-cultured,” meaning readily obtained fluids and substances were sent immediately to begin cultures. Due to concerns for bacterial gastroenteritis, she received ceftriaxone in the emergency department and ciprofloxacin after admission. Fevers continued and blood cultures yielded Escherichia coli, which was phenotypically resistant to most antibiotics, including ceftriaxone and ciprofloxacin, but susceptible to “last-resort” carbapenems, which were then used to treat her.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1128/MICROBE.11.209.1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63639474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Repurposing Drugs, and Fresh Outcomes from Other Familiar Sources 重新利用药物和其他熟悉来源的新结果
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/microbe.11.193.1
J. Fox
{"title":"Repurposing Drugs, and Fresh Outcomes from Other Familiar Sources","authors":"J. Fox","doi":"10.1128/microbe.11.193.1","DOIUrl":"https://doi.org/10.1128/microbe.11.193.1","url":null,"abstract":"In the face of new and emerging infectious disease threats, it is prudent to look back at old or even ancient sources to uncover a drug or entity that might work anew or in a different context, according to several researchers who spoke during the 2016 ASM Biodefense and Emerging Diseases Research Meeting last February. Here, let us consider the old in three specific ways: revisiting licensed drugs, using old phage for new purposes, and looking at old beasts for new antimicrobials.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63639513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sequencing, Not Culture, Proved Fast Way To Find New Hot Spring Virus 测序而非培养被证明是发现新的温泉病毒的快速方法
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/MICROBE.11.195.1
C. Potera
{"title":"Sequencing, Not Culture, Proved Fast Way To Find New Hot Spring Virus","authors":"C. Potera","doi":"10.1128/MICROBE.11.195.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.195.1","url":null,"abstract":"Culture-independent methods are making it possible to discover and partly characterize viruses and their hosts straight from hot springs such as those in Yellowstone National Park (YNP)—short-circuiting the traditional approach that depends on first growing samples in vitro, according to Rebecca Hochstein at Montana State University (MSU) in Bozeman and her collaborators. In this way, they discovered the Acidianus tailed spindle virus (ATSV), which infects archaeal species found in the Crater Hills Thermal Basin of YNP. Details appeared 13 January 2016 in the Journal of Virology (doi:10.1128/JVI.03098–15).","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63639219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unexpected Taxa and Mixotrophy Help To “Sink” Carbon in Oceans 意想不到的分类群和混合营养有助于“吸收”海洋中的碳
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/MICROBE.11.196.1
B. Digregorio
{"title":"Unexpected Taxa and Mixotrophy Help To “Sink” Carbon in Oceans","authors":"B. Digregorio","doi":"10.1128/MICROBE.11.196.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.196.1","url":null,"abstract":"In nutrient-poor regions of the ocean, several types of “unexpected taxa” are “most strongly associated with carbon export,” according to Lionel Guidi from the CNRS Laboratoire d'Oceanographie de Villefranche-sur-Mer in France and his collaborators. Separately, but also unexpectedly, mixotrophy appears to play a larger than previously appreciated role in sequestering carbon into the ocean's depths, according to Ben Ward from the University of Bristol in the United Kingdom and Michael Follows of the Massachusetts Institute of Technology in Cambridge, Mass.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63639329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ink and LED 墨水和LED
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/MICROBE.11.188.1
S. Maloy
{"title":"Ink and LED","authors":"S. Maloy","doi":"10.1128/MICROBE.11.188.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.188.1","url":null,"abstract":"This edition of Microbe magazine marks a new experiment with digital publishing. It is our first online-only edition. It has become common for people to do more and more reading on digital devices, whether reading scientific articles at our desk or catching up with the latest news on our mobile devices.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63638750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tuna Can Harbor Histamine-Producing Bacteria 金枪鱼能滋生产生组胺的细菌
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/microbe.11.192.1
D. Holzman
{"title":"Tuna Can Harbor Histamine-Producing Bacteria","authors":"D. Holzman","doi":"10.1128/microbe.11.192.1","DOIUrl":"https://doi.org/10.1128/microbe.11.192.1","url":null,"abstract":"Tuna fish may carry bacteria that, even at lowered temperatures, grow and retain histidine decarboxylase (HDC) enzyme activity, raising questions about the potential for those enzymes producing histamines in refrigerated fresh tuna, according to Kristin Bjornsdottir-Butler, of the Gulf Coast Seafood Laboratory, a Food and Drug Administration research facility on Dauphin Island, Ala., and her collaborators. These cold-tolerant, histamine-producing bacteria are indigenous to the fish, not contaminants introduced during handling, the researchers note. Details appeared 29 January 2016 in Applied and Environmental Microbiology (doi:10.1128/AEM.02833–15/).","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63639377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibiotic Resistance Spreads through Diverse Species and Habitats, Part I: The public health threat amplifies as drug-resistant pathogens move freely through various environments and species 抗生素耐药性通过不同的物种和栖息地传播，第一部分:随着耐药病原体在各种环境和物种中自由移动，公共卫生威胁扩大
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/MICROBE.11.201.1
Shannon Weiman
{"title":"Antibiotic Resistance Spreads through Diverse Species and Habitats, Part I: The public health threat amplifies as drug-resistant pathogens move freely through various environments and species","authors":"Shannon Weiman","doi":"10.1128/MICROBE.11.201.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.201.1","url":null,"abstract":"Antibiotic-resistant bacteria continue to spread across the globe—directly affecting human and animal patients while also establishing reservoirs from which those strains continue to emerge long into the future, according to several researchers who spoke during the 2015 ICAAC conference held in San Diego last September. Their findings paint a broader and, in some ways, more alarming picture of the expanding influence and dynamic nature of antibiotic resistance than experts previously drew.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63639407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Postdoc Life 博士后生活
Microbe (Washington, D.C.) Pub Date : 2016-05-01 DOI: 10.1128/microbe.11.189.1
Cara McDonough
{"title":"The Postdoc Life","authors":"Cara McDonough","doi":"10.1128/microbe.11.189.1","DOIUrl":"https://doi.org/10.1128/microbe.11.189.1","url":null,"abstract":"I am not a scientist. But I've observed a scientist's life—including late-night time points and stress over preliminary exams—since I first started dating my now-husband when he was a Ph.D. candidate at the University of North Carolina.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63639038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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