Microbe (Washington, D.C.)最新文献

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Different Strokes: Blending Microbiology and Art: Microbiologists collaborating with artists uncover new ways to find beauty and importance in microbes and to make them into art 不同的笔触:混合微生物学和艺术:微生物学家与艺术家合作,发现新的方法来发现微生物的美和重要性,并使它们成为艺术
Microbe (Washington, D.C.) Pub Date : 2016-12-01 DOI: 10.1128/MICROBE.11.421.1
J. Maloy
{"title":"Different Strokes: Blending Microbiology and Art: Microbiologists collaborating with artists uncover new ways to find beauty and importance in microbes and to make them into art","authors":"J. Maloy","doi":"10.1128/MICROBE.11.421.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.421.1","url":null,"abstract":"Although Michele Banks is not a microbiologist, she found herself speaking to a packed room of microbiologists at the 2016 ASM Microbe meeting in Boston last June. “It all started with the paint,” she says. “I was working with wet-in-wet watercolor, making abstract paintings with a kind of bleeding look and fuzzy edges. I had a show at Children's National Medical Center in Washington, D.C., and the art coordinator told me that … my work looked like ‘friendly little things under a microscope.’”","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63642209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Universal Influenza Vaccine: Quest in Sight?: Several efforts to develop a vaccine that might work against all or most flu virus strains fortify hopes for fulfilling this one-time “flight of fancy” 通用流感疫苗:探索在望?当前位置研发一种可能对抗所有或大多数流感病毒株的疫苗的努力,增强了实现这一一次性“幻想”的希望
Microbe (Washington, D.C.) Pub Date : 2016-12-01 DOI: 10.1128/MICROBE.11.433.1
Marlene Cimons
{"title":"Universal Influenza Vaccine: Quest in Sight?: Several efforts to develop a vaccine that might work against all or most flu virus strains fortify hopes for fulfilling this one-time “flight of fancy”","authors":"Marlene Cimons","doi":"10.1128/MICROBE.11.433.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.433.1","url":null,"abstract":"William Schaffner, professor of medicine at Vanderbilt University in Nashville, Tenn., and medical director of the National Foundation for Infectious Diseases, remembers the countless times he and other flu experts mused about the possibilities of a universal vaccine, one that would not need modifying each year. These days, however, thanks to modern molecular technology, this dream no longer appears so improbable. “Now or very soon, these may no longer be flights of fancy,” he says. “There are some very impressive scientific efforts underway to make this real.”","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1128/MICROBE.11.433.1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63642385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
One 2016 Nobel: Yeast-Based Autophagy Work; 3 MacArthurs: Microbiology 2016年诺贝尔奖:基于酵母的自噬工作;3麦克阿瑟:微生物学
Microbe (Washington, D.C.) Pub Date : 2016-12-01 DOI: 10.1128/MICROBE.11.419.1
J. Fox
{"title":"One 2016 Nobel: Yeast-Based Autophagy Work; 3 MacArthurs: Microbiology","authors":"J. Fox","doi":"10.1128/MICROBE.11.419.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.419.1","url":null,"abstract":"The 2016 Nobel Prize in Physiology or Medicine, about $936,000 this year, recognizes Yoshinori Ohsumi of Japan for his efforts to understand autophagy, a fundamental process for degrading and recycling cellular components, research that he began by studying yeast. Separately, among the 2016 MacArthur Foundation Fellows, who receive $625,000 “genius awards,” are microbiologist Dianne Newman, who studies bacteria that played roles in shaping the Earth as well as in modern biomedical contexts; geobiologist Victoria Orphan, whose focus is on microbial communities in extreme environments; and physical biologist Manu Prakash, who invented several devices that can be used for diagnostic work in microbiology. Also noteworthy, the 2016 LaskerDeBakey Clinical Medical Research Award is shared by three scientists whose research on hepatitis C virus (HCV) led to development of drugs for treating HCV infections.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1128/MICROBE.11.419.1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63642425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Crystalized Proteins from Thermophile Reveal Transcription Insights 从嗜热菌中结晶的蛋白质揭示转录的见解
Microbe (Washington, D.C.) Pub Date : 2016-09-01 DOI: 10.1128/MICROBE.11.377.1
C. Potera
{"title":"Crystalized Proteins from Thermophile Reveal Transcription Insights","authors":"C. Potera","doi":"10.1128/MICROBE.11.377.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.377.1","url":null,"abstract":"The recently determined three-dimensional (3D) structure of a bacterial class II transcription complex helps to reveal how it binds to specific DNA sequences, thus driving transcription of downstream genes. This X-ray-based structural analysis provides the first atomic structure for such an intact class II transcription activation complex, according to Richard H. Ebright at Rutgers University in Piscataway, N.J. He and his colleagues reported their findings on 10 June 2016 in Science (doi:10.1126/science.aaf4417).","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63641647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Branches: ASM Activity at the Local Level: 分会:ASM在地方层面的活动:
Microbe (Washington, D.C.) Pub Date : 2016-09-01 DOI: 10.1128/MICROBE.11.396.2
T. Soule, S. Knight
{"title":"Branches: ASM Activity at the Local Level:","authors":"T. Soule, S. Knight","doi":"10.1128/MICROBE.11.396.2","DOIUrl":"https://doi.org/10.1128/MICROBE.11.396.2","url":null,"abstract":"","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63641905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reviews and Resources:Houston, We Have a Narrative: Why Science Needs Story: BOOKS 评论和资源:休斯顿,我们有一个叙述:为什么科学需要故事:书籍
Microbe (Washington, D.C.) Pub Date : 2016-09-01 DOI: 10.1128/MICROBE.11.404.2
Dennis F. Mangan
{"title":"Reviews and Resources:Houston, We Have a Narrative: Why Science Needs Story: BOOKS","authors":"Dennis F. Mangan","doi":"10.1128/MICROBE.11.404.2","DOIUrl":"https://doi.org/10.1128/MICROBE.11.404.2","url":null,"abstract":"Randy Olson gives us yet another tool for our communication belts…and I'm glad to say my pants are beginning to sag! We are blessed to have excellent books, videos, podcasts, blogs, online training, and workshops available to help us improve our communication skills. One of the best books I've come across recently is Olson's Houston, We Have a Narrative: Why Science Needs Story. Following his popular book, Don't Be Such a Scientist (2009), Olson takes a deeper analysis of the substance (not style) of science communication, which remains shamefully in need of improvement. I am delighted to report that by applying some of the methods explained in this book, Olson is helping me and many other emotionally stingy scientists, engineers, and technicians better connect with fellow humans.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1128/MICROBE.11.404.2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63641958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reviews and Resources:The Amoeba in the Room (Lives of the Microbes): BOOKS 评论和资源:房间里的变形虫(微生物的生命):书籍
Microbe (Washington, D.C.) Pub Date : 2016-09-01 DOI: 10.1128/MICROBE.11.404.1
A. Huang
{"title":"Reviews and Resources:The Amoeba in the Room (Lives of the Microbes): BOOKS","authors":"A. Huang","doi":"10.1128/MICROBE.11.404.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.404.1","url":null,"abstract":"Although most introductory biology courses offered in high school or college contain at least one session that examines microscopic organisms, Nicholas Money feels that these small organisms deserve much more attention and research support. So he passionately and expertly goes on to demonstrate that there are all sorts of fascinating and weird microbes in the earth, in the water, in the air, and even in and on our bodies. They don't just exist but have essential roles interacting intimately with each other, their environment, and the larger hosts that they inhabit. Over time these small organisms have even begun to share some or all of their genetic information, sometimes integrating their genetic information into the DNA of the host or existing as organelles within the host cell.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63641950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Candidate Antimicrobials, Enhancers, Potentiators, Combos Plus New Probe 候选抗菌剂,增强剂,增强剂,组合加上新的探针
Microbe (Washington, D.C.) Pub Date : 2016-09-01 DOI: 10.1128/MICROBE.11.375.1
J. Fox
{"title":"Candidate Antimicrobials, Enhancers, Potentiators, Combos Plus New Probe","authors":"J. Fox","doi":"10.1128/MICROBE.11.375.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.375.1","url":null,"abstract":"Several new antibacterial candidates shared the stage with promising agents that augment antimicrobial drugs, combination agents that work better than their separate components, and antifungal candidate agents—presented this year during the poster summary session “Early New Antimicrobial Agents,” convened at the 2016 ASM Microbe Meeting, held in Boston, Mass., in June. In addition, participants learned briefly about a new imaging approach for following the course of infections and the drugs or drug candidates that are used and being developed, respectively, to treat them. Although these new antimicrobial agents appear potentially useful, none of them looks startling or could be called a breakthrough.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1128/MICROBE.11.375.1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63641539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eat Prey, Love? Diverse Soil Cercozoa Tell Tales of Climate Change 吃猎物,爱?多样的土壤尾蚴讲述气候变化的故事
Microbe (Washington, D.C.) Pub Date : 2016-09-01 DOI: 10.1128/MICROBE.11.378.1
C. Potera
{"title":"Eat Prey, Love? Diverse Soil Cercozoa Tell Tales of Climate Change","authors":"C. Potera","doi":"10.1128/MICROBE.11.378.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.378.1","url":null,"abstract":"The enormous species diversity of Cercozoa, important soil protozoans that feed on bacteria there, might provide a means for following climate change trends, according to Flemming Ekelund at the University of Copenhagen in Denmark and his collaborators. Thus, as soil dries with the changes in climate, species composition within the Cercozoa will also likely change, affecting further decomposition within this environmental niche, they say. Meanwhile, high-throughput sequencing of genomic material from soil samples can be used to follow protozoan predators and their prey. Details appeared 8 March 2016 in The ISME Journal (doi:10.1038/ismej.2016.31).","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63641783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microbes as Intein Havens: These microbial, intron-like polypeptides are self-splicing elements that remove themselves posttranslationally from their host proteins 微生物作为内含子的避风港:这些微生物,内含子样多肽是自剪接元件,在翻译后从宿主蛋白中移除自己
Microbe (Washington, D.C.) Pub Date : 2016-09-01 DOI: 10.1128/MICROBE.11.388.1
Cathleen M. Green, M. Belfort
{"title":"Microbes as Intein Havens: These microbial, intron-like polypeptides are self-splicing elements that remove themselves posttranslationally from their host proteins","authors":"Cathleen M. Green, M. Belfort","doi":"10.1128/MICROBE.11.388.1","DOIUrl":"https://doi.org/10.1128/MICROBE.11.388.1","url":null,"abstract":"Inteins are polypeptide escape artists, with an extraordinary ability to excise themselves from fully folded proteins without leaving a trace. Inteins are best described as protein introns, self-splicing elements that remove themselves posttranslationally from their host proteins. They occur in all three domains of life—archaea, bacteria, and single-celled eukaryotes (Fig. 1A). Even so, inteins are rarely discussed among microbiologists, but this relative silence is about to be broken.","PeriodicalId":87479,"journal":{"name":"Microbe (Washington, D.C.)","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"63641898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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