Virome Affects Host Immune Status, Susceptibility to Range of Diseases

Shannon Weiman
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Abstract

While the limelight shines on the bacterial microbiome for its role in shaping human health and disease, the virome remains more in the shadows. However, viruses associated with human hosts can have profound impacts on their health, according to several researchers who spoke during the ASM 2016 Microbe Conference held in Boston last June. Even though some chronic viral infections appear asymptomatic, the viral particles being generated during such latent periods can stimulate innate immune responses, dictating immune reactivity as well as susceptibility to infections and inflammatory and other diseases, including cancer.
病毒影响宿主免疫状态,对一系列疾病的易感性
虽然细菌微生物群在塑造人类健康和疾病方面的作用引起了人们的关注,但病毒群更多地处于阴影之中。然而,根据去年6月在波士顿举行的2016年ASM微生物会议上发言的几位研究人员的说法,与人类宿主相关的病毒会对他们的健康产生深远的影响。尽管一些慢性病毒感染似乎没有症状,但在这种潜伏期产生的病毒颗粒可以刺激先天免疫反应,决定免疫反应以及对感染、炎症和其他疾病(包括癌症)的易感性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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