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Paediatric and perinatal drug therapy最新文献

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Drug Development: a Perspective from Africa 药物开发:来自非洲的视角
Paediatric and perinatal drug therapy Pub Date : 2002-05-01 DOI: 10.1185/146300902322125091
G. Anabwani
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引用次数: 6
Drug Development for Children 儿童药物开发
Paediatric and perinatal drug therapy Pub Date : 2002-05-01 DOI: 10.1185/146300902322125082
A. Smyth, I. Choonara
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引用次数: 1
The Caffeine Breath Test and CYP1A2 Activity in Children 儿童咖啡因呼气试验与CYP1A2活性的关系
Paediatric and perinatal drug therapy Pub Date : 2002-05-01 DOI: 10.1185/146300902322125136
E. Webster, J. McIntyre, I. Choonara, T. Preston
{"title":"The Caffeine Breath Test and CYP1A2 Activity in Children","authors":"E. Webster, J. McIntyre, I. Choonara, T. Preston","doi":"10.1185/146300902322125136","DOIUrl":"https://doi.org/10.1185/146300902322125136","url":null,"abstract":"The caffeine breath test is a non-invasive method of studying CYP1A2 activity that is suitable for children from the ages of 3 years upwards. It involves the oral administration of a stable isotope and the collection of breath samples for a period of 2 hours. Breath samples are analysed by continuous flow isotope ratio mass spectrometry. It has been used to study both drug interactions and the effect of disease on drug metabolism.","PeriodicalId":87451,"journal":{"name":"Paediatric and perinatal drug therapy","volume":"5 1","pages":"28-33"},"PeriodicalIF":0.0,"publicationDate":"2002-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65623672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Unlicensed and off-label prescription of systemic anti-infective agents to children 未经许可和标签外处方全身性抗感染药物给儿童
Paediatric and perinatal drug therapy Pub Date : 2002-01-01 DOI: 10.1185/146300902322125929
Geert W. ‘t Jong, I. Eland, M. de Hoog, M.C.J.M. Sturkenboom, J. N. van den Anker, Bruno C. Stricker
{"title":"Unlicensed and off-label prescription of systemic anti-infective agents to children","authors":"Geert W. ‘t Jong, I. Eland, M. de Hoog, M.C.J.M. Sturkenboom, J. N. van den Anker, Bruno C. Stricker","doi":"10.1185/146300902322125929","DOIUrl":"https://doi.org/10.1185/146300902322125929","url":null,"abstract":"","PeriodicalId":87451,"journal":{"name":"Paediatric and perinatal drug therapy","volume":"5 1","pages":"68-74"},"PeriodicalIF":0.0,"publicationDate":"2002-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65623969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
A Prospective Study of Intranasal Midazolam for Children with Acute Seizures 咪达唑仑鼻内治疗儿童急性癫痫发作的前瞻性研究
Paediatric and perinatal drug therapy Pub Date : 2000-12-01 DOI: 10.1185/1463009001505259
S. Conroy, R. Morton, H. Dixon, A. Porter, I. Choonara
{"title":"A Prospective Study of Intranasal Midazolam for Children with Acute Seizures","authors":"S. Conroy, R. Morton, H. Dixon, A. Porter, I. Choonara","doi":"10.1185/1463009001505259","DOIUrl":"https://doi.org/10.1185/1463009001505259","url":null,"abstract":"Objective: To evaluate the use and safety of intranasal midazolam when used as first-line treatment for children with acute seizures. Study design: Prospective study of 20 children over the age of six months presenting with an acute seizure to the emergency department of a 70-bed children’s hospital in the UK. All children were treated with intranasal midazolam in a dose of 200 micrograms/kg. Efficacy and toxicity were assessed. Results: Midazolam controlled the seizure within 15 minutes in 10 patients (50%). A further five patients (25%) showed a partial response. Five children showed no response to midazolam. No adverse reactions were seen. Conclusion: This efficacy rate is lower than that shown in other studies. All studies to date have been small. It is suggested that larger, controlled studies are required to establish the place of midazolam, and alternative routes of administration, such as the intranasal route, in the treatment of children with acute seizures.","PeriodicalId":87451,"journal":{"name":"Paediatric and perinatal drug therapy","volume":"4 1","pages":"52-57"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65623571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Two Major Advances for our Journal 我们期刊的两个主要进展
Paediatric and perinatal drug therapy Pub Date : 2000-12-01 DOI: 10.1185/1463009001505295
I. Choonara, A. Nunn
{"title":"Two Major Advances for our Journal","authors":"I. Choonara, A. Nunn","doi":"10.1185/1463009001505295","DOIUrl":"https://doi.org/10.1185/1463009001505295","url":null,"abstract":"","PeriodicalId":87451,"journal":{"name":"Paediatric and perinatal drug therapy","volume":"4 1","pages":"34-34"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65623790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antibiotics for Acute Otitis Media in Infancy: Based on Fear or on Facts? 婴儿急性中耳炎的抗生素治疗:基于恐惧还是基于事实?
Paediatric and perinatal drug therapy Pub Date : 2000-12-01 DOI: 10.1185/1463009001505231
R. Damoiseaux
{"title":"Antibiotics for Acute Otitis Media in Infancy: Based on Fear or on Facts?","authors":"R. Damoiseaux","doi":"10.1185/1463009001505231","DOIUrl":"https://doi.org/10.1185/1463009001505231","url":null,"abstract":"","PeriodicalId":87451,"journal":{"name":"Paediatric and perinatal drug therapy","volume":"4 1","pages":"58-61"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65623513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paediatric Therapeutics in the USA and Internationally: An Unparalleled Opportunity 儿科治疗在美国和国际:一个无与伦比的机会
Paediatric and perinatal drug therapy Pub Date : 2000-12-01 DOI: 10.1185/1463009001505312
S. Spielberg
{"title":"Paediatric Therapeutics in the USA and Internationally: An Unparalleled Opportunity","authors":"S. Spielberg","doi":"10.1185/1463009001505312","DOIUrl":"https://doi.org/10.1185/1463009001505312","url":null,"abstract":"","PeriodicalId":87451,"journal":{"name":"Paediatric and perinatal drug therapy","volume":"4 1","pages":"71-74"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65623380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Nitrous Oxide and Oxygen Mixture (Entonox®), and Acute Procedural Pain 氧化亚氮和氧气混合物(Entonox®)，急性程序性疼痛
Paediatric and perinatal drug therapy Pub Date : 2000-12-01 DOI: 10.1185/1463009001505277
M. Vater, Debra Hessell
{"title":"Nitrous Oxide and Oxygen Mixture (Entonox®), and Acute Procedural Pain","authors":"M. Vater, Debra Hessell","doi":"10.1185/1463009001505277","DOIUrl":"https://doi.org/10.1185/1463009001505277","url":null,"abstract":"","PeriodicalId":87451,"journal":{"name":"Paediatric and perinatal drug therapy","volume":"4 1","pages":"35-44"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65623679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
The European Society for Developmental Pharmacology (ESDP) 欧洲发展药理学学会(ESDP)
Paediatric and perinatal drug therapy Pub Date : 2000-12-01 DOI: 10.1185/1463009001505268
G. Pons, R. Gorodischer
{"title":"The European Society for Developmental Pharmacology (ESDP)","authors":"G. Pons, R. Gorodischer","doi":"10.1185/1463009001505268","DOIUrl":"https://doi.org/10.1185/1463009001505268","url":null,"abstract":"","PeriodicalId":87451,"journal":{"name":"Paediatric and perinatal drug therapy","volume":"4 1","pages":"62-66"},"PeriodicalIF":0.0,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65623618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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