Acute cardiac carePub Date : 2014-09-01Epub Date: 2014-05-16DOI: 10.3109/17482941.2014.911915
Alberto Palazzuoli, Gaetano Ruocco, Matteo Beltrami, Beatrice Franci, Marco Pellegrini, Barbara Lucani, Ranuccio Nuti, Claudio Ronco
{"title":"Admission plasma neutrophil gelatinase associated lipocalin (NGAL) predicts worsening renal function during hospitalization and post discharge outcome in patients with acute heart failure.","authors":"Alberto Palazzuoli, Gaetano Ruocco, Matteo Beltrami, Beatrice Franci, Marco Pellegrini, Barbara Lucani, Ranuccio Nuti, Claudio Ronco","doi":"10.3109/17482941.2014.911915","DOIUrl":"https://doi.org/10.3109/17482941.2014.911915","url":null,"abstract":"<p><strong>Unlabelled: </strong>Abstract Background: The role of neutrophil gelatinase-associated lipocalin (NGAL) has been described in chronic heart failure (HF), however less data are available in patients admitted for acute HF.</p><p><strong>Methods: </strong>We evaluated the role of NGAL in predicting in-hospital worsening renal function (WRF) and post-discharge follow-up during six months period in patients with acute HF. All patients were submitted to creatinine, estimated glomerular filtration rate (eGFR), blood urea nitrogen (BUN) and B-type natriuretic peptide (BNP) measurement during hospitalization and before discharge.</p><p><strong>Results: </strong>Patients with chronic kidney dysfunction (CKD) demonstrated higher NGAL respect to subject with preserved renal function (241 ± 218 and 130 ± 80 ng/ml; P = 0.0001). In subgroup that developed WRF during hospitalization, NGAL levels were significantly increased respect to patients without WRF (272 ± 205 versus 136 ± 127 ng/ml; P = 0.0001). A cut off of 134 ng/ml has been related to WRF with good sensibility and specificity (92% and 71% AUC 0.83; P = 0.001). Multivariable Cox regression analysis showed that cut-off of 134 ng/ml was the only marker related to death (HR: 1.75; 95% CI: 1.24-2.45; P < 0.001). Follow-up analysis confirmed that NGAL > 130 ng/ml was associated with adverse events during a six-month period.</p><p><strong>Conclusion: </strong>Admission NGAL measurement appears a sensible tool for in-hospital WRF prediction as well as an early marker for adverse outcome during post discharge vulnerable phase.</p>","PeriodicalId":87385,"journal":{"name":"Acute cardiac care","volume":"16 3","pages":"93-101"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/17482941.2014.911915","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32349997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acute cardiac carePub Date : 2014-09-01Epub Date: 2014-06-23DOI: 10.3109/17482941.2014.920089
Shams Y-Hassan, Magnus Settergren, Loghman Henareh
{"title":"Sepsis-induced myocardial depression and takotsubo syndrome.","authors":"Shams Y-Hassan, Magnus Settergren, Loghman Henareh","doi":"10.3109/17482941.2014.920089","DOIUrl":"https://doi.org/10.3109/17482941.2014.920089","url":null,"abstract":"<p><strong>Unlabelled: </strong>Abstract Background and objectives: Myocardial depression in the setting of sepsis and septic shock is common and has been recognized for a long time. The aim of this study is to find out an association and causal link between sepsis and takotsubo syndrome (TS).</p><p><strong>Methods: </strong>Fifteen cases of TS were studied. Critical review of the literature dealing with sepsis and myocardial depression was done Results: Fifteen cases of sepsis-induced TS are described. Fifty-three per cent of the patients were men. The ages ranged from 39 to 76 years (mean age 60 years). Two-thirds of the patients had ST-elevation myocardial infarction ECG changes. Complications occurred in 80% of the patients. No specific types of sepsis or micro-organisms were associated with the development of TS. Critical review of the sepsis-induced myocardial depression shows that the left ventricular dysfunction, which is reversible within one-to-two weeks, is characterized by segmental ventricular dysfunction, and involvement of the right ventricle in one fourth of cases. These features are also consistent with TS.</p><p><strong>Conclusions: </strong>Sepsis triggers TS, which may be the cause of the majority of cases of sepsis-induced myocardial depression. Acute cardiac sympathetic disruption with noradrenaline spill-over may be the cause of sepsis-induced TS.</p>","PeriodicalId":87385,"journal":{"name":"Acute cardiac care","volume":"16 3","pages":"102-9"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/17482941.2014.920089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32446307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acute cardiac carePub Date : 2014-09-01Epub Date: 2014-05-27DOI: 10.3109/17482941.2014.911916
Kaveh Sadigh, Sandeep Gupta, Muzammil H Musani, Kathleen Stergiopoulos
{"title":"Sinister syncope.","authors":"Kaveh Sadigh, Sandeep Gupta, Muzammil H Musani, Kathleen Stergiopoulos","doi":"10.3109/17482941.2014.911916","DOIUrl":"https://doi.org/10.3109/17482941.2014.911916","url":null,"abstract":"ischemic necrosis of multiple loops of small bowel with evidence of pan-jejunal and ileal pneumatosis. He was urgently referred for exploratory laparotomy, superior mesenteric embolectomy, and extensive small bowel resection. Pathologic specimen revealed malignant tumor cells present within thrombus material, consistent with tumor emboli. Cardiac magnetic resonance imaging of the intracardiac mass revealed intramuscular invasion of the tumor without extension beyond the cardiac borders (Figure 3). Intraoperative transesophageal echocardiography (Figures 4 and 5, Supplementary Video 1 to be found online at http://informahealthcare.com/doi/abs/ 10.3109/17482941.2014.911916) revealed a large mass with highly mobile components, with no other cardiac tumor noted. Eventual wide resection of the intracardiac tumor, which required partial myomectomy and mitral valve replacement due to its extensive nature, revealed a poorly diff erentiated malignant neoplasm with an extensive","PeriodicalId":87385,"journal":{"name":"Acute cardiac care","volume":"16 3","pages":"112-3"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/17482941.2014.911916","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32370855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful retrieval of broken coiled guidewire from left atrium during balloon mitral valvotomy: a rare complication.","authors":"Surender Deora, Dheeraj More, Sanjay Shah, Tejas Patel","doi":"10.3109/17482941.2014.921311","DOIUrl":"https://doi.org/10.3109/17482941.2014.921311","url":null,"abstract":"<p><p>Abstract Balloon mitral valvotomy (BMV) is the procedure of choice for rheumatic mitral stenosis with favorable valve morphology. Fracture of 0.025 inch coiled guidewire during BMV is a very rare complication. The various factors which may cause this complication are utilization of reused hardware, improper placement of guidewire, abnormal angulation between guidewire and dilator with forceful septal dilation and rarely manufacturing defect. Here, we report successful retrieval of broken 0.025 inch coiled guidewire from left atrium during BMV using 10F Amplatzer long sheath without any complication. </p>","PeriodicalId":87385,"journal":{"name":"Acute cardiac care","volume":"16 3","pages":"110-1"},"PeriodicalIF":0.0,"publicationDate":"2014-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/17482941.2014.921311","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32402343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acute cardiac carePub Date : 2014-06-01Epub Date: 2014-04-22DOI: 10.3109/17482941.2014.902469
Ronny Cohen, Thierry Mallet, Brooks Mirrer, Pablo Loarte, Michael Gale, Paul Kastell
{"title":"A fatal case of peripartum cardiomyopathy.","authors":"Ronny Cohen, Thierry Mallet, Brooks Mirrer, Pablo Loarte, Michael Gale, Paul Kastell","doi":"10.3109/17482941.2014.902469","DOIUrl":"https://doi.org/10.3109/17482941.2014.902469","url":null,"abstract":"<p><p>Peripartum cardiomyopathy is a life-threatening cardiac condition affecting pregnant women either late in pregnancy or early in the post-partum period. The latest studies show a dramatic improvement in the mortality rates of women affected with this disorder, which has been correlated with advances in medical therapy for heart failure. However, patients continue to die of this condition. The following case report describes a typical patient with peripartum cardiomyopathy diagnosed on clinical grounds, along with echocardiogram findings of severe systolic dysfunction and global hypokinesis consistent with dilated cardiomyopathy. Emergency cesarean delivery had to be performed for fetal distress. There was significant improvement of the patient's condition with standard pharmacological management for heart failure at the time of discharge. However, five weeks after discharge, fatal cardiac arrest occurred. It is hoped that this article will raise awareness about this rare but potentially fatal condition and promote understanding of its main clinical features, diagnostic criteria, and conventional pharmacological management.</p>","PeriodicalId":87385,"journal":{"name":"Acute cardiac care","volume":"16 2","pages":"78-82"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/17482941.2014.902469","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32282581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acute cardiac carePub Date : 2014-06-01Epub Date: 2014-04-10DOI: 10.3109/17482941.2014.902468
Jackson J Liang, Eric R Fenstad
{"title":"Loeys-Dietz syndrome.","authors":"Jackson J Liang, Eric R Fenstad","doi":"10.3109/17482941.2014.902468","DOIUrl":"https://doi.org/10.3109/17482941.2014.902468","url":null,"abstract":"A 25-year-old man presented with abdominal pain. He was tall with arachnodactyly and hypermobile joints. Family history was unremarkable. CT angiogram revealed a descending aortic dissection extending superiorly from a 4.5 cm infrarenal abdominal aortic aneurysm (Figure 1). He was managed medically in the hospital and discharged with recommendations for close interval imaging. One month later he returned to the Emergency Department with chest pain. CT angiogram demonstrated proximal expansion of the dissection to the left subclavian artery (Figure 2). Woven vascular graft s were utilized to repair the thoracoabdominal","PeriodicalId":87385,"journal":{"name":"Acute cardiac care","volume":"16 2","pages":"90-1"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/17482941.2014.902468","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32253447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acute cardiac carePub Date : 2014-06-01Epub Date: 2014-04-21DOI: 10.3109/17482941.2014.902470
Osereme Irivbogbe, Brooks Mirrer, Pablo Loarte, Michael Gale, Ronny Cohen
{"title":"Thrombolytic-related complication in a case of misdiagnosed myocardial infarction.","authors":"Osereme Irivbogbe, Brooks Mirrer, Pablo Loarte, Michael Gale, Ronny Cohen","doi":"10.3109/17482941.2014.902470","DOIUrl":"https://doi.org/10.3109/17482941.2014.902470","url":null,"abstract":"<p><p>The importance of early thrombolysis in acute myocardial infarction has been highlighted in several large trials. The clinical decision is often taken by physicians who need to take a rapid action with the risk of misdiagnosing non-coronary events that mimic myocardial infarction. Here we describe a case of acute pericarditis in a 37-year-old man whom received thrombolysis and developed a sudden hemorrhagic pericardial effusion that evolved rapidly into a cardiac tamponade. These errors leading to lethal thrombolysis complications have been surprisingly rare; but a correct diagnosis of aortic dissection or hemorrhagic pericarditis needs to be stressed because even after obtaining the correct diagnosis, the prolonged disturbance of hemostasis prevents a rapid therapy being instigated.</p>","PeriodicalId":87385,"journal":{"name":"Acute cardiac care","volume":"16 2","pages":"83-7"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/17482941.2014.902470","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32278706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acute cardiac carePub Date : 2014-06-01Epub Date: 2014-03-21DOI: 10.3109/17482941.2014.889313
John Palios, Stephen Clements, Stamatios Lerakis
{"title":"Chest pain due to hiatal hernia mimicking as cardiac mass.","authors":"John Palios, Stephen Clements, Stamatios Lerakis","doi":"10.3109/17482941.2014.889313","DOIUrl":"https://doi.org/10.3109/17482941.2014.889313","url":null,"abstract":"<p><p>Based on a case of suspected ischemic heart disease we review hiatal hernia causing chest pain. Rest echocardiography images were suggestive of cardiac mass in the left atrium. Dobutamine stress echocardiogram was negative for inducible ischemia. Multi-slice computed tomography of the chest was performed showing that a large hiatal hernia was present compressing on the left atrium. Multimodality imaging is necessary for suspected mass compressing the heart, causing chest discomfort.</p>","PeriodicalId":87385,"journal":{"name":"Acute cardiac care","volume":"16 2","pages":"88-9"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/17482941.2014.889313","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32195178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acute cardiac carePub Date : 2014-06-01Epub Date: 2014-03-21DOI: 10.3109/17482941.2014.889310
Chiara Lazzeri, Andrea Sori, Pasquale Bernardo, Marco Chiostri, Eleonora Tommasi, Mery Zucchini, Salvatore Mario Romano, Gian Franco Gensini, Serafina Valente
{"title":"Cardiovascular effects of mild hypothermia in post-cardiac arrest patients by beat-to-beat monitoring. A single centre pilot study.","authors":"Chiara Lazzeri, Andrea Sori, Pasquale Bernardo, Marco Chiostri, Eleonora Tommasi, Mery Zucchini, Salvatore Mario Romano, Gian Franco Gensini, Serafina Valente","doi":"10.3109/17482941.2014.889310","DOIUrl":"https://doi.org/10.3109/17482941.2014.889310","url":null,"abstract":"<p><strong>Background: </strong>Data on the hemodynamic and cardiovascular effects of hypothermia in patients with cardiac arrest are scarce. The aim of this study was to evaluate the hemodynamic changes induced by hypothermia by means of Most Care(®) (pressure recording analytical method, PRAM methodology), a beat-to-beat hemodynamic monitoring method.</p><p><strong>Methods: </strong>We enrolled 20 patients with cardiac arrest (CA) consecutively admitted to our intensive cardiac care unit and treated with mild hypothermia (TH).</p><p><strong>Results: </strong>While non-survivors showed no changes in haemodynamic variables throughout the study period, survivors exhibited a significant increase in systemic vascular resistance indexed during hypothermia and a trend towards lower values of heart rate and higher levels of mean arterial pressure.</p><p><strong>Conclusions: </strong>According to our data, PRAM methodology proved to be a feasible and clinically useful tool in CA patients treated with TH since it provides continuous beat-to-beat haemodynamic monitoring that is based on assessment of several haemodynamic variables. Moreover, we observed that survivors showed a different haemodynamic behaviour during hypothermia in respect to patients who died. However, further studies, performed in larger cohorts, are needed to better elucidate the haemodynamic effects of hypothermia in CA patients by means of PRAM methodology.</p>","PeriodicalId":87385,"journal":{"name":"Acute cardiac care","volume":"16 2","pages":"67-73"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/17482941.2014.889310","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32196268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acute cardiac carePub Date : 2014-06-01Epub Date: 2014-03-26DOI: 10.3109/17482941.2014.881504
Niklas Bergh, Oskar Angerås, Per Albertsson, Christian Dworeck, Göran Matejka, Inger Haraldsson, Dan Ioanes, Berglind Libungan, Jacob Odenstedt, Petur Petursson, Wilhelm Ridderstråle, Truls Råmunddal, Elmir Omerovic
{"title":"Does the timing of treatment with intra-aortic balloon counterpulsation in cardiogenic shock due to ST-elevation myocardial infarction affect survival?","authors":"Niklas Bergh, Oskar Angerås, Per Albertsson, Christian Dworeck, Göran Matejka, Inger Haraldsson, Dan Ioanes, Berglind Libungan, Jacob Odenstedt, Petur Petursson, Wilhelm Ridderstråle, Truls Råmunddal, Elmir Omerovic","doi":"10.3109/17482941.2014.881504","DOIUrl":"https://doi.org/10.3109/17482941.2014.881504","url":null,"abstract":"<p><strong>Background: </strong>Intra-aortic balloon pump (IABP) counterpulsation and primary percutaneous coronary intervention (PCI) are standard treatment modalities in cardiogenic shock (CS) complicating acute myocardial infarction. The aim of this study was to investigate the impact of the timing of IABP treatment start in relation to PCI procedure.</p><p><strong>Methods: </strong>Data were obtained from the SCAAR registry (Swedish Coronary Angiography and Angioplasty Registry) about 139 consecutive patients with CS due to ST-elevation myocardial infarction (STEMI) who received IABP treatment. The patients were hospitalized at Sahlgrenska University Hospital, Gothenburg, during 2004-2008. The cohort was divided into the two groups: group (A) in whom IABP treatment started before start of PCI (n = 72) and group (B) in whom IABP treatment started after PCI treatment (n = 67). The primary endpoint was 30-day mortality. Propensity score (PS) adjusted Cox proportional hazards regression was used to analyze predictors of 30-day mortality.</p><p><strong>Results: </strong>Mean age was 66.5 ± 12 and 28% were women. All patients have received IABP treatment 30 min before or 30 min after primary PCI. 63% had diabetes and 28% had hypertension. 16% were active tobacco smokers. The mortality rate at 30 days was 38%. IABP treatment commenced before or after PCI was not an independent predictor of mortality (P = 0.72).</p><p><strong>Conclusion: </strong>In this non-randomized trial the treatment with insertion of IABP before primary PCI in patients with CS due to STEMI is not associated with a more favorable outcome as compared with IABP started after primary PCI.</p>","PeriodicalId":87385,"journal":{"name":"Acute cardiac care","volume":"16 2","pages":"57-62"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/17482941.2014.881504","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32209051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}