Journal of orthopedic research and therapy最新文献

{"title":"Adipose Tissue-Derived Mesenchymal Stem Cells (AD-MSC) Versus Platelet-Rich Plasma (PRP) in the Arthroscopic Treatment of Chondral Defects of The Knee: What’s The Best? A Histological and Clinical Evaluation","authors":"Michele, Venosa, Massimo Angelozzi, Ylli Alicka, Francesco, Calafiore, V. Calvisi, E. Romanini","doi":"10.29011/2575-8241.001255","DOIUrl":"https://doi.org/10.29011/2575-8241.001255","url":null,"abstract":"Adipose Tissue-Derived Mesenchymal Stem Cells (AD-MSC","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47626562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Results of Copeland Shoulder Resurfacing Arthroplasty in Sickle Cell Patients with Humeral Head Avascular Necrosis","authors":"","doi":"10.29011/2575-8241.001254","DOIUrl":"https://doi.org/10.29011/2575-8241.001254","url":null,"abstract":"","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42766484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiphoton Imaging of Blood Vessels and Mesenchymal Progenitor Cells in Callus of Mice with Tibial Fracture Longitudinally","authors":"","doi":"10.29011/2575-8241.001247","DOIUrl":"https://doi.org/10.29011/2575-8241.001247","url":null,"abstract":"","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42446885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphometry of The Sternum in Osteosynthetic Reconstruction","authors":"S. Reindl, Paul Schuller, M. Meller, M. Beyer, J. Decker, S. Raab","doi":"10.29011/2575-8241.001242","DOIUrl":"https://doi.org/10.29011/2575-8241.001242","url":null,"abstract":"Introduction: Osteosynthetic reconstruction of the sternum can be challenging in thoracic surgery. Osteometric data on the complex anatomy of the sternal bone is needed for the choice of appropriate reconstruction techniques. Sternum clips may be an alternative to current available osteosynthesis. Materials & Methods: Width, intercostal distances, thickness and length of the sternum as well as the distance of the internal thoracic arteries were analyzed in 50 patients who had undergone chest CT. Gender-specific correlation analyses between height, weight and sternum measurements were performed. It was investigated whether sternum clips are the right size to be used on patients concerning osteometric parameters. Results: 50 patients (m:f = 31:19) aged 64.3 (14.3) years were examined. Body dimensions were 171.4 (9.4) cm height and 76.7 (14.8) kg weight. Osteometric data of the sternum could be assessed as follows: length 53.4 (5.9) mm for manubrium, 98.8 (14.0) mm for corpus and 46.5 (10.7) mm for xiphoid process. The vertical distance between two adjacent intercostal spaces was 29.0 (7.4) mm. The distance to the internal thoracic artery was 14.6 (1.3) mm. A correlation between body dimensions and bone morphometry could be found for the length of the sternum. There are gender-specific differences in length, but not in width. Conclusion: The suitability of sternum clips regarding their size and dimensions could be anatomically demonstrated for almost all sternum bones. However, this cannot be done in all cases on the manubrium and the costal arch. Osteosynthesis can be adapted to the sternal dimensions of the individual patient.","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48056147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chondrogenic Differentiation of Human Wharton’s Jelly and Bone Marrow-Derived Mesenchymal Stem Cells: Focus on the Role of an Acrylamide-Free Cross-Linked Hyaluronic Acid Hydrogel","authors":"Letizia Pelusi, Valeria Schiavone, G. Bologna, Pietro Cerritelli, Deborah Lezza, A. Pantalone, Manuela Santalucia, R. Buda, A. Pandolfi, Domitilla Mandatori","doi":"10.29011/2575-8241.001209","DOIUrl":"https://doi.org/10.29011/2575-8241.001209","url":null,"abstract":"Hyaluronic Acid (HA) is a natural biopolymer commonly used to reduce inflammatory process in degenerative joint disease such as Osteoarthritis (OA). In the last years, its possible use as biocompatible scaffold for cartilage tissue engineering was highlighted. In this field, to achieve promising results, recent studies have underlined the advantages of combining tissue engineering and cell therapy approaches. To date, the mainly cells employed for cartilage regeneration are Mesenchymal Stem Cells (MSCs) isolate from bone marrow. However, since their use has several limitations, there was a growing interesting in MSCs from perinatal tissue, such as umbilical cord, as possible source for cartilage regeneration. Therefore, the aim of this study was to investigate the role of an innovative acrylamide-free cross-linked HA Hydrogel formulation (HyLink®) on chondrogenic differentiation process employing both human umbilical cord Wharton’s jellyand Bone Marrow-derived MSC (hUC-WJ-MSC s and hBM-MSCs). Our data showed that the HyLink improved the chondrogenic differentiation in both mesenchymal cellular models as revealed by the increase of Glycosaminoglycans (GAGs) deposition and the mRNA levels of chondrogenic markers (SOX9, COL2a1 and ACAN). In addition, the results demonstrated that hUC-WJ-MSC have a greater cartilage differentiation potential compared to the MSCs isolated from bone marrow. Overall, our results demonstrate that HyLink improves chondrogenic differentiation process both in hBM-MSCs and hUC-WJ-MSC . Since the latest showed greater cartilage differentiation potential, we suggest that MSCs isolated from perinatal tissue might be a promising cell source for regenerative medicine in the orthopedic field. Citation: Pelusi L, Schiavone V, Bologna G, Cerritelli P, Lezza D, et al. (2021) Chondrogenic Differentiation of Human Wharton’s Jelly and Bone Marrow-Derived Mesenchymal Stem Cells: Focus on the Role of an Acrylamide-Free Cross-Linked Hyaluronic Acid Hydrogel. J Orthop Res Ther 6: 1209. DOI: 10.29011/2575-8241.001209 2 Volume 6; Issue 06 J Orthop Ther, an open access journal ISSN: 2575-8241","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41479460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Influencing Peri-Operative Patient Satisfaction in Arthroscopic Procedures of Shoulder Joint in Beach Chair Position under Isolated Regional Anaesthesia","authors":"","doi":"10.29011/2575-8241.001190","DOIUrl":"https://doi.org/10.29011/2575-8241.001190","url":null,"abstract":"","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69468136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Our Experience in the Management of Subtrochanteric Femoral Fractures in Children","authors":"","doi":"10.29011/2575-8241.001187","DOIUrl":"https://doi.org/10.29011/2575-8241.001187","url":null,"abstract":"","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69468018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pain Management Associated with Total Joint Arthroplasty: Current Concepts","authors":"","doi":"10.29011/2575-8241.001191","DOIUrl":"https://doi.org/10.29011/2575-8241.001191","url":null,"abstract":"","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69468148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of a Novel Type of Shock Wave (Diamagnetic Shock Wave) in the Treatment of the Osteoarthrosis of the Thumb: A Case Series Study and a Look upon a Painless Mechanotherapy","authors":"","doi":"10.29011/2575-8241.001186","DOIUrl":"https://doi.org/10.29011/2575-8241.001186","url":null,"abstract":"","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69468260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased Adhesion of (Cna) Positive Staphylococcus Aureus to Damaged Articular Cartilage","authors":"","doi":"10.29011/2575-8241.001194","DOIUrl":"https://doi.org/10.29011/2575-8241.001194","url":null,"abstract":"","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69469153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}