Journal of orthopedic research and therapy最新文献

Defining The Disease of Movement Dysfunction Related Low Back Pain - An Observational Study and Description of The Necessary Paradigm Shift Required to Cure the Root Cause of Globally Prevalent Low Back Pain Symptoms 定义与运动功能障碍相关的腰背痛疾病--一项观察性研究，并描述治疗全球普遍腰背痛症状的根本原因所需的必要范式转变

Journal of orthopedic research and therapy Pub Date : 2023-11-10 DOI: 10.29011/2575-8241.001327

引用次数: 0

Comparatively Low End-of-Life Care Self-Efficacy Among Junior Nurses in the Operating Room in China: A Cross-Sectional Survey 中国手术室初级护士临终关怀自我效能较低的横断面调查

Journal of orthopedic research and therapy Pub Date : 2023-10-04 DOI: 10.29011/2575-8241.001322

引用次数: 0

Return to Play and Long-Term Participation Following ACL Reconstruction in Elite Handball Players 优秀手球运动员ACL重建后的恢复和长期参与

Journal of orthopedic research and therapy Pub Date : 2023-10-04 DOI: 10.29011/2575-8241.001324

{"title":"Return to Play and Long-Term Participation Following ACL Reconstruction in Elite Handball Players","authors":"","doi":"10.29011/2575-8241.001324","DOIUrl":"https://doi.org/10.29011/2575-8241.001324","url":null,"abstract":"Abstract Purpose: The consequences of Anterior Cruciate Ligament (ACL) injury and subsequent reconstruction in handball players are understudied. The aim of the present study is to present the effects of ACL reconstruction exclusively on handball players regarding return to play. Methods: Fourteen knees with an ACL tear in twelve patients were included in the study. Nine injuries ( ) occurred during games, and five ( during training. The mechanism of injury was non-contact in of cases. All cases were treated with a hamstrings autograft. Results: The athletes returned to unrestricted full team training in a mean of 7.7 months. Return to competitive play was achieved in twelve of the fourteen cases ( in a mean time of 9.6 months post-operatively. Nine of the athletes that returned to play ( ) reached the same level of competition as before injury. At a mean follow-up of 37.1 months post-operatively, of the players included in the study and of those that returned to play were still active players; all playing at their pre-injury competition level. There was one recurrence of an ACL tear ( , while two athletes ( had a contralateral ACL rupture during the follow-up period. All athletes - including the ones that quitted - had excellent knee scores at the latest follow-up. IKDC mean score was 94.7 Lysholm mean score was 95 EuroQoL mean score was 100, and KOOS mean score was 97.3. Conclusions: A high proportion of elite handball players can return to play following ACL reconstruction with a low rate of recurrence. However, not all players can stay in the sport for long and this should be kept in mind when an ACL tear occurs.","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135646448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nurses with Low Willingness to Stay in New Hospital District and Need More Social Support: A Cross-Sectional Survey 新医院区护士留守意愿低、社会支持需求高的横断面调查

Journal of orthopedic research and therapy Pub Date : 2023-10-04 DOI: 10.29011/2575-8241.001323

引用次数: 0

A CT based 3D Algorithm for Diagnosis of DDH and Quantification of Surgical Correction 基于CT的DDH三维诊断及手术矫正量化算法

Journal of orthopedic research and therapy Pub Date : 2023-09-21 DOI: 10.29011/2575-8241.001321

引用次数: 0

Preliminary Experience of Carbon Fiber Buttress Plating: A Case Series 碳纤维凸台电镀的初步经验——案例系列

Journal of orthopedic research and therapy Pub Date : 2023-09-06 DOI: 10.29011/2575-8241.001318

Bryce Allen Hendrix, Aaron Schrayer, John C.P. Floyd

{"title":"Preliminary Experience of Carbon Fiber Buttress Plating: A Case Series","authors":"Bryce Allen Hendrix, Aaron Schrayer, John C.P. Floyd","doi":"10.29011/2575-8241.001318","DOIUrl":"https://doi.org/10.29011/2575-8241.001318","url":null,"abstract":"Metal has long been the basis for implants used in orthopedic surgery. The first metals used were stainless steel and cobalt-chrome based alloys with progression through the years to include titanium, nickel, and most recently, carbon fiber.[1] Multiple previous studies describe carbon fiber as a safe, biocompatible material that can be used in problematic fractures. [2-6] However to our knowledge, no study has examined the use of carbon fiber specifically in buttress plate application. Compared to conventional metal implants, carbon fiber offers several potential benefits. It provides a modulus of elasticity closer to that of bone, improved fatigue strength, and more complete imaging compatibility. [3-6] In addition, carbon fiber has a large elastic deformation phase with little to no plastic deformation, and it is this distinctive quality that would seem to make carbon fiber potentially ideal for buttress plate fracture fixation. The objective of this case series was to outline the preliminary experience of carbon fiber buttress plating in ankle fractures. This study was performed at a level II trauma center and includes four patients that underwent open reduction and internal fixation with carbon fiber buttress plating for either a bimalleolar equivalent fracture, bimalleolar ankle fracture, or trimalleolar ankle fracture. The main outcome measure included radiographic fracture visualization of healing, adverse tissue reaction, infection, subsequent fracture, or hardware failure. Overall, all patients achieved union with no adverse effects, drawing to the conclusion that carbon fiber is a safe and effective alternative when used in a buttress plate fashion,","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41333198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanism of TGFβ in Bone Metastases and its Potential Therapeutic Uses 转化生长因子β在骨转移瘤中的作用机制及其潜在的治疗作用

Journal of orthopedic research and therapy Pub Date : 2023-08-16 DOI: 10.29011/2575-8241.001316

Shahid A Akhund, Khalid Said, Khalid S. Mohammad

{"title":"Mechanism of TGFβ in Bone Metastases and its Potential Therapeutic Uses","authors":"Shahid A Akhund, Khalid Said, Khalid S. Mohammad","doi":"10.29011/2575-8241.001316","DOIUrl":"https://doi.org/10.29011/2575-8241.001316","url":null,"abstract":"Complications associated with advanced cancer pose a clinical challenge, particularly when bone metastases are involved, as they can worsen the prognosis and reduce the patient’s chances of survival. Solid tumors, such as those originating from the breast, prostate, and lungs, can potentially metastasize to bone. Mineralized bone matrices contain potent growth factors and cytokines. The bone microenvironment is distinctive, furnishing prolific soil for cancer cell proliferation. Following tumor-induced bone destruction by osteoclast, the Transforming Growth Factor (TGFβ) is released from the mineralized bone matrix. It is one of the most abundant growth factors released from the bone matrix. TGFβ stimulates tumor cell secretion of factors that accelerate bone resorption and stimulate tumor cell colonization. Consequently, TGFβ is essential for fueling cancer’s vicious cycle of cancer growth and bone destruction. In addition, TGFβ promotes Epithelial-Mesenchymal Transition (EMT), increasing cell invasiveness, angiogenesis, and metastasis progression. Emerging evidence demonstrates that TGFβ inhibits immune responses, allowing opportunistic cancer cells to evade immune checkpoints and promote bone metastasis. By inhibiting TGFβ signaling pathways, cancer progression in the bone could be broken, EMT could be reversed, and immune response could be improved. However, the dual function of TGFβ as both a tumor suppressor and an enhancer pose a formidable obstacle to developing therapeutics that target TGFβ signaling. This review delves into the significance of TGFβ in the advancement of cancer and bone metastases, in addition to examining the current therapeutic prospects of TGFβ pathway targeting.","PeriodicalId":87310,"journal":{"name":"Journal of orthopedic research and therapy","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48375417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effects of Exercise with Blood Flow Restriction (BFR) in the Post Operative Rehabilitation of Anterior Cruciate Ligament (ACL) Reconstruction Patients: A Case Series 血流量限制运动（BFR）在前交叉韧带（ACL）重建患者术后康复中的作用：一系列病例

Journal of orthopedic research and therapy Pub Date : 2023-08-07 DOI: 10.29011/2575-8241.001314

Christina Karampampa, Efthymios Papasoulis, Dimitrios Hatzimanouil, Georgios Koutras, Trifon Totlis, I. Terzidis

引用次数: 0

Gastrointestinal Manifestations of Hypermobile Ehlers-Danlos Syndrome and Dietary Approaches Related to Their Management 高活动性埃勒斯-丹洛斯综合征的胃肠道表现及其相关的饮食管理方法

Journal of orthopedic research and therapy Pub Date : 2023-07-28 DOI: 10.29011/2575-8241.001313

Lauren Steiner, Anne Bodensteiner, Nathaniel R. Johnson

引用次数: 0

Platelet-to-Lymphocyte Ratio (PLR) and Lymphocyte-to-Monocyte Ratio (LMR) at Admission Predict Survival in Hip Fracture Patients 入院时血小板与淋巴细胞比率（PLR）和淋巴细胞与单核细胞比率（LMR）预测髋部骨折患者的生存率

Journal of orthopedic research and therapy Pub Date : 2023-07-12 DOI: 10.29011/2575-8241.001311

引用次数: 0