{"title":"Deficiency of Vitamin E and Dehydration as a Cause of Deep Venous Thrombosis in a Child with Cystic Fibrosis","authors":"V. Velmishi","doi":"10.33552/GJPNC.2021.03.000556","DOIUrl":"https://doi.org/10.33552/GJPNC.2021.03.000556","url":null,"abstract":"Deep Vein Thrombosis (DVT) is caused by a blood clot that occurs in the deep venous system. DVTs are rare in they healthy children, but may occur more commonly in children that are hospitalized or have chronic diseases. Children with cystic fibrosis have a higher risk to develop deep vein thrombosis. Signs and symptoms of DVT include swelling, pain, and changes in skin color of the affected limb. Diagnosis of DVT is usually confirmed with an imaging test such as an ultrasound. Treatment for DVT includes waiting and watching to see what happens, medication, thrombolysis, or surgery. We describe a child with cystic fibrosis who presented a deep vein thrombosis of left leg as a cause of dehydration and vitamin E deficiency","PeriodicalId":87261,"journal":{"name":"Global journal of pediatrics & neonatal care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48805089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H J Odendaal, I C Crockart, C Du Plessis, L Brink, C A Groenewald
{"title":"Accelerations of the Fetal Heart Rate in the Screening for Fetal Growth Restriction at 34-38 Week's Gestation.","authors":"H J Odendaal, I C Crockart, C Du Plessis, L Brink, C A Groenewald","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>To use machine learning to determine what information on Doppler velocimetry and maternal and fetal heart rates, collected at 20-24 weeks gestation, correlates best with fetal growth restriction according to the estimated fetal weight at 34-38 weeks.</p><p><strong>Study design: </strong>Data of 4496 pregnant women, collected prospectively for the Safe Passage Study, from August 2007 to August 2016, were used for the present analysis. Doppler flow velocity of the uterine, umbilical, and middle cerebral arteries and transabdominally recorded maternal and fetal ECGs were collected at 20-24 weeks gestation and fetal biometry collected at 34-38 weeks from which the estimated fetal weight was calculated. Fetal growth restriction was defined as an estimated fetal weight below the 10th centile. Accelerations and decelerations of the fetal and maternal heart rates were quantified as gained or lost beats per hour of recording respectively. Machine learning with receiver operative characteristic curves were then used to determine which model gives the best performance.</p><p><strong>Results: </strong>The final model performed exceptionally well across all evaluation metrics, particularly so for the Stochastic Gradient Descent method: achieving a 93% average for Classification Accuracy, Recall, Precision and F1-Score to identify the fetus with an estimated weight below the 10th percentile at 34-38 weeks. Ranking determined that the most important standard feature was the umbilical artery pulsatility index. However, the excellent overall accuracy is likely due to the value added by the pre-processed features regarding fetal gained beats and accelerations.</p><p><strong>Conclusion: </strong>Fetal movements, as characterized by gained beats as early as 20-24 weeks gestation, contribute to the value of the flow velocimetry of the umbilical artery at 34-38 weeks in identifying the growth restricted fetus.</p>","PeriodicalId":87261,"journal":{"name":"Global journal of pediatrics & neonatal care","volume":"3 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8607280/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39765353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neonatal Metabolic Acidosis after Intrauterine Exposure to Acetazolamide","authors":"S. Shukla","doi":"10.33552/GJPNC.2020.03.000554","DOIUrl":"https://doi.org/10.33552/GJPNC.2020.03.000554","url":null,"abstract":"Acetazolamide is a commonly used drug for intracranial hypertension. Teratogenic and metabolic effects of acetazolamide on a fetus have sparsely been reported. Here, we report a neonate presenting with hyperchloremic metabolic acidosis associated with maternal use of acetazolamide during pregnancy. Case description: A term female infant was born to a mother with normal prenatal course. During pregnancy, the mother was treated with acetazolamide for idiopathic intracranial hypertension. She presented with hyperchloremic metabolic acidosis soon after birth and was admitted to the neonatal intensive care unit for further evaluation and management. The serum bicarbonate and serum chloride concentrations were 12 mmol/L and 110 mmol/L respectively with normal remaining laboratory parameters. No other cause for metabolic acidosis was identified. Infant was treated conservatively with intravenous fluids and laboratory studies normalized over the next 48 hours. Conclusion: The safety of using acetazolamide during pregnancy is not well established. This case points to possible fetal metabolic side effects of in utero exposure to acetazolamide. Potential exposure to maternal medications should be considered while evaluating neonatal metabolic acidosis with normal physical examination.","PeriodicalId":87261,"journal":{"name":"Global journal of pediatrics & neonatal care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42302289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Novel Method of Management of Hyperbilirubinemia","authors":"W. Boutwell","doi":"10.33552/GJPNC.2020.03.000552","DOIUrl":"https://doi.org/10.33552/GJPNC.2020.03.000552","url":null,"abstract":"","PeriodicalId":87261,"journal":{"name":"Global journal of pediatrics & neonatal care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43745493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of the Pacifiers in Children with Disabilities","authors":"Sun-Joung L An","doi":"10.33552/gjpnc.2020.02.000549","DOIUrl":"https://doi.org/10.33552/gjpnc.2020.02.000549","url":null,"abstract":"Pacifiers are commonly used with babies all around the world. Pacifiers are used primarily to stimulate sucking and to calm self. These pacifiers, “also known as soothers, dummies and artificial teats are as rooted in history as they are in controversy” [1]. Recommendations for and against its use are given to parents from various professionals including nurses, doctors, dentists and therapists grounded on the benefits or risks.","PeriodicalId":87261,"journal":{"name":"Global journal of pediatrics & neonatal care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45508455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of the Pacifiers in Children with Disabilities","authors":"Michael Stark","doi":"10.33552/gjpnc.2020.02.000548","DOIUrl":"https://doi.org/10.33552/gjpnc.2020.02.000548","url":null,"abstract":"","PeriodicalId":87261,"journal":{"name":"Global journal of pediatrics & neonatal care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49496098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic Emergency CT Imaging Utilization in Our University Hospital Radiology Unit for Pediatrics","authors":"B. T. Baştuğ","doi":"10.33552/gjpnc.2020.02.000547","DOIUrl":"https://doi.org/10.33552/gjpnc.2020.02.000547","url":null,"abstract":"Purpose: This study aimed to make the distribution of Computed Tomography (CT) imaging according to organ systems in pediatric emergent patients that admitted to our University Hospital Emergency Radiology Unit. Methods and Materials: This was a retrospective study comparing resource application between March 2016 and September 2017 in a single ED in a university hospital. Results: In 32 patient thorax and abdomen CT has studied together for multiple trauma. In 106 head CT was taken for traumatic pathologies. In 34 abdominal CT has studied alone for abdominal emergencies like appendicitis, renal calculi, etc. In 9 orbital CT, in 4 vertebral column CT, in 2 temporal CT, in 13 extremities CT and in 110 head and cervical CT together were done for trauma. In 6 patient head CT with contrast administration was done for suspicion of an intracranial mass. In 10 thorax CT have studied for parenchymal infiltrations whom clinic and laboratory tests were positive. In 1 femoral artery CT angiography was done for detection of traumatic injury. Conclusion: When the reasons for referral to emergency radiology CT unit of pediatric patients were examined, the most common causes in our center were trauma and abdomen problems.","PeriodicalId":87261,"journal":{"name":"Global journal of pediatrics & neonatal care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45948260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neonatal Risk Factors for Term Newborn Mortality at the Sylvanus Olympio University Hospital from 2013 to 2017","authors":"Tchagbele Ouro Bagna","doi":"10.33552/gjpnc.2020.02.000546","DOIUrl":"https://doi.org/10.33552/gjpnc.2020.02.000546","url":null,"abstract":"The reduction of neonatal mortality requires the identification of its risk factors. The objective of this study was to assess the causes of death in term newborns at the Sylvanus Olympio University Hospital Center (CHU SO). Material and method: This was a retrospective descriptive and analytical study of term newborns who died in hospital. The main parameters studied were clinical and therapeutic data and causes of death. Results: The hospital frequency of mortality of term newborns was 10.3%, of which 84.4% in the early neonatal period. Neonatal factors associated with early neonatal death were perinatal asphyxia, neonatal infection and congenital malformations, resuscitation in the delivery room. Inborn transfer and triple antibiotic therapy in the newborn were protective factors. Conclusion: Neonatal mortality remains a major public health problem in Togo. Huge efforts remain to be made in the surveillance and follow- up of the mother, fetus and newborn. were age, sex, perinatal manifestations, clinical data, treatment received at birth and in hospital, and causes of death.","PeriodicalId":87261,"journal":{"name":"Global journal of pediatrics & neonatal care","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48616238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}