Clinical obstetrics, gynecology and reproductive medicine最新文献

{"title":"Differences in Sexual Function Between Trimesters During Pregnancy: An Observational Study","authors":"S. Soysal, A. Sarioz, Umran Kilincdemir Turgut, G. Anik Ilhan, Yusuf Arman, B. Yildizhan, T. Pekin","doi":"10.21613/gorm.2020.1073","DOIUrl":"https://doi.org/10.21613/gorm.2020.1073","url":null,"abstract":"OBJECTIVE: The aim of this study was to evaluate differences in sexual function between trimesters, and factors (in addition to pregnancy) that influence sexual function during pregnancy.STUDY DESIGN: This observational study was conducted at a tertiary referral center with 372 pregnant women. Seventy-two of the women did not complete the questionnaire (rejections or missing data) and the overall response rate was 80.6%. Among the remaining women, 43 of them excluded due to depression. Beck Depression Inventory was used to evaluate depression. Index of female sexual function questionnaire was used to assess sexual function. Index of female sexual function had a total and six sub-domain scores which assess the quality and frequency of sexual intercourse, desire, overall satisfaction, ability to achieve orgasm, and degree of clitoral sensation (c.sensation).RESULTS: Total index of female sexual function and quality, satisfaction, orgasm, and c.sensation sub-domain scores were lowest in the third trimester. Older age, lower level of education, and lower level of income negatively affected total index of female sexual function scores. Quality scores were lowest in older women and women with lower education. Frequency scores were highest during the second trimester. Desire scores were highest in women aged between 18 and 25 years, in women who were newly married (1-3 years), and during the second trimester. Satisfaction scores were lowest in women older than 35 years, and highest in newly married women. Orgasm scores were highest in women aged 18-25 years, in newly married women. CONCLUSIONS: Sexual function in women during the third trimester of pregnancy is generally affected negatively.","PeriodicalId":87233,"journal":{"name":"Clinical obstetrics, gynecology and reproductive medicine","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84668952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Prospective Study to Evaluate the Predictivity of Risk Malignancy Index in Adnexal Masses","authors":"Narin Yar Elmastas, M. Obut, S. Tunc","doi":"10.21613/gorm.2020.1057","DOIUrl":"https://doi.org/10.21613/gorm.2020.1057","url":null,"abstract":"OBJECTIVE: To evaluate the efficiency of CA-125, menopausal status, ultrasound features and risk malignancy index in predicting malignancy in patients with an adnexal mass.STUDY DESIGN: This study was designed prospectively and 212 patients who applied to our hospital and met the study criteria were included. Preoperatively RMI value was calculated for the differentiation of benign from malignant patients. The diagnosis was confirmed by histopathology. Kolmogorov-Smirnov, Yates correction, Pearson Chi-Square and Student's t-test were used for statistical analysis. ROC curves were drawn as diagnostic tests and the test results were presented.RESULTS: Of 212 patients included in our study, 174 (82%) patients’ were reported as benign, 6 (3%) borderline and 32 (15%) malignant. In predicting malignancy, the malignity risk index with 200 cutoff value the sensitivity and specivity was 87% and 80% respectively. However, when the cutoff value of malignity risk index taken as 112, the sensitivity was unchanged but the specificity increased to 90%. Similarly, when CA-125's cutoff value was taken as 46U/mL, the sensitivity did not change but the specificity increased from 68% to 72%.CONCLUSION: Malignancy risk index is a method that has high sensitivity and specificity. Preoperative-op RMI calculation can provide accurate predictions for the establishment of an appropriate surgical plan for pelvic masses or referral to tertiary centers.","PeriodicalId":87233,"journal":{"name":"Clinical obstetrics, gynecology and reproductive medicine","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87661494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Bacterial Vaginosis and Skin Disorders in Patients with Autoimmune Antibody Positivity","authors":"B. Beksaç, Hanife Guler Donmez","doi":"10.21613/gorm.2020.1103","DOIUrl":"https://doi.org/10.21613/gorm.2020.1103","url":null,"abstract":"OBJECTIVE: To investigate the association of bacterial vaginosis and skin disorders in patients with autoimmune antibody positivity.STUDY DESIGN: This retrospective study consisted of 80 patients with autoimmune antibody positivity. All patients were evaluated for the presence of bacterial vaginosis and skin disorders. Cervicovaginal smears were used for the definitive diagnosis of bacterial vaginosis. RESULT: We found bacterial vaginosis in 13.75% (11/80) of the cases. 1 (9.1%) and 10 (90.9%) cases had skin disorders in bacterial vaginosis positive and negative groups respectively (p=0.531). CONCLUSION: There is no relationship between bacterial vaginosis and the presence of skin disorders in patients with autoimmune antibody positivity.","PeriodicalId":87233,"journal":{"name":"Clinical obstetrics, gynecology and reproductive medicine","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87243376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy Wastage Due to Fetal Congenital Malformations","authors":"V. Sangwan, Shivani Khandelwal, R. Mahendru, Pinkey Lakra, Sunita Siwach","doi":"10.21613/gorm.2020.1095","DOIUrl":"https://doi.org/10.21613/gorm.2020.1095","url":null,"abstract":"OBJECTIVES: To study the pattern of various congenital anomalies in rural Haryana.STUDY DESIGN: This was a retrospective study conducted over 1 and ½ years (from January 2015 to June 2016) in a tertiary care center in Haryana, India.RESULTS: Out of 11,178 births, 227 babies had gross congenital malformations 2.03%. In literature, the most common birth defect reported in western countries is cardiovascular anomalies while in India and eastern countries, it’s the neural tube defect. In our study also, neural tube defects were the most common congenital anomalies accounting for 64.31% of total anomalies. They were more common in unbooked patients (70%) and the rural population. So, the main cause appears to be a lack of awareness and illiteracy.CONCLUSION: There is a need for increased awareness and folic acid supplementation routinely in the periconceptional period to decrease the incidence of congenital anomalies.","PeriodicalId":87233,"journal":{"name":"Clinical obstetrics, gynecology and reproductive medicine","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72741602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Index","authors":"","doi":"10.1097/01.grf.0000666112.56637.64","DOIUrl":"https://doi.org/10.1097/01.grf.0000666112.56637.64","url":null,"abstract":"","PeriodicalId":87233,"journal":{"name":"Clinical obstetrics, gynecology and reproductive medicine","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81863006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Sperm Parameters on Pregnancy Rate in Patients Undergoing Intrauterine Insemination","authors":"Mehmet Solakhan, M. Demir","doi":"10.21613/gorm.2020.1040","DOIUrl":"https://doi.org/10.21613/gorm.2020.1040","url":null,"abstract":"OBJECTIVE: In this study, the effects of sperm parameters on the success of intrauterine insemination were investigated. STUDY DESIGN: The data from 309 infertile couples who were admitted between 2012-2018 without a female factor were analyzed retrospectively and included in the study. After the administration of gonadotropin and hCG (5000-10000 IU), single insemination was performed in 36-40 hours in all cycles. All couples underwent routine infertility screening. The relationship between sperm parameters (motility, morphology, sperm count), patient age, duration of infertility with intrauterine insemination success was evaluated.RESULTS: There was no statistically significant difference between the two groups in terms of mean age and age related-parity. There was no statistically significant difference between male ages, liquefaction, and sperm volumes between the two groups (p=0.898, p=0.448, p=0.651). Before washing; There was a statistically significant difference between the sperm concentration, percentage of total motile sperm, percentage of progressive motility sperm, percentage of normal sperm morphology, and total sperm count between the two groups (p=0.0001, p=0.0001, p=0.0001, p=0.0001, p=0.0001). After sperm washing; the results were similar to those obtained before washing. While statistically significant difference was observed between sperm volume and sperm concentrations (p=0.023, p=0.018), no significant difference was observed between the two groups in total sperm count (p=0.612).CONCLUSION: As a result, during the application of intrauterine insemination to infertile couples, total motile sperm count, progressive motility sperm count ratio and high sperm ratio with normal morphology used in order to increase pregnancy success can be considered as criteria that increase the chances of success.","PeriodicalId":87233,"journal":{"name":"Clinical obstetrics, gynecology and reproductive medicine","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80383177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Miscarriage Rates Due to Endometriosis: A Retrospective Cohort Study","authors":"P. Calis, G. Işık, Dilara Duygulu, N. Bozkurt, D. Karçaaltıncaba","doi":"10.21613/gorm.2020.1058","DOIUrl":"https://doi.org/10.21613/gorm.2020.1058","url":null,"abstract":"OBJECTIVE: To find the differences of miscarriage rates between pregnant patients with and without endometriosis. STUDY DESIGN: The retrospective cohort study was conducted in the Department of Obstetrics and Gynecology, School of Medicine, Gazi University between January-2015 and December-2018. Patients were divided into two groups; endometriosis and non-endometriosis according to their pathology report and ultrasound examination. In both groups, miscarriage rates and in vitro fertilization pregnancy ratios were analyzed. Miscarriage rates in in vitro fertilization pregnancies and in endometriosis group who had and didn't have surgery also analyzed.RESULTS: Sixty-two patients in the study group and 65 patients in the control group were included. There was no significant difference in miscarriage rates between endometriosis and non-endometriosis group (20/62 (32%) and 13/65 (20%), respectively, p=0.124). There was a statistically significant difference in miscarriage rates between in vitro fertilization and non-in vitro fertilization group (p=0.004). Apart from that, in in vitro fertilization group, the miscarriage rate was higher in the endometrioma subgroup than non-endometrioma (p=0.008).CONCLUSION: There was an only significant difference in miscarriage rate in the in vitro fertilization group between endometrioma and non-endometrioma patients. In the future, there should be more studies to define the actual pathophysiology for miscarriage with endometriosis.","PeriodicalId":87233,"journal":{"name":"Clinical obstetrics, gynecology and reproductive medicine","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80636754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Larger Fetal Ascending Aorta Than the Pulmonary Artery Indicate Major Cardiac Anomaly?","authors":"Ş. Baran, A. Arslan, G. Doğan Durdağ, H. Kalaycı, Seda Yuksel Simsek, Songül Alemdaroğlu","doi":"10.21613/gorm.2020.1060","DOIUrl":"https://doi.org/10.21613/gorm.2020.1060","url":null,"abstract":"OBJECTIVE: This study investigated the cases in which the fetal ascending aorta is larger than the main pulmonary artery on the three-vessel view and aimed to determine the relationship between the larger ascending aorta and major cardiac anomalies.STUDY DESIGN: Pregnancies between 18-24 gestational weeks who underwent detailed second-trimester screening during 2015-2019 were evaluated. Cases whose fetal ascending aorta diameter was larger than fetal main pulmonary artery diameter on the three-vessel view despite normal four-chamber view were analyzed. Prenatal and postnatal echocardiography studies were performed for each case.RESULTS: Fetal ascending aorta diameter larger than fetal main pulmonary artery diameter on the three-vessel view despite normal four-chamber view was detected in 21 fetuses in a total of 3810 pregnancies (0.55%), and 10 (47.6%) of them had major congenital heart disease. The diagnosis of Tetralogy of Fallot, double outlet right ventricle, ventricular septal defect, pulmonary valve stenosis, and moderate to severe tricuspid regurgitation were confirmed with prenatal/postnatal echocardiography studies. The highest ratio of ascending aorta/main pulmonary artery was 1.4 in a fetus with a double outlet right ventricle and pulmonary valve stenosis.CONCLUSION: The fetal ratio of ascending aorta/main pulmonary artery larger than 1 on the three-vessel view may be a sign of certain cardiac anomalies. Nevertheless, this rate is not an indicator of a serious cardiac defect in all cases. Fetal advanced echocardiography and early postnatal cardiac evaluation should be done to confirm the diagnosis.","PeriodicalId":87233,"journal":{"name":"Clinical obstetrics, gynecology and reproductive medicine","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80963751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contributors: Liver Disease in Pregnancy.","authors":"","doi":"10.1097/01.grf.0000654132.31566.f4","DOIUrl":"https://doi.org/10.1097/01.grf.0000654132.31566.f4","url":null,"abstract":"","PeriodicalId":87233,"journal":{"name":"Clinical obstetrics, gynecology and reproductive medicine","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77851480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nurse Practitioner Managed Outpatient Induction Onto Buprenorphine/Naloxonein Women With Opioid Use Disorder During Pregnancy: A Retrospective Cohort Analysis","authors":"","doi":"10.24966/rmgo-2574/100036","DOIUrl":"https://doi.org/10.24966/rmgo-2574/100036","url":null,"abstract":"A Cohort Analysis. Abstract Objective: To compare maternal, fetal and neonatal clinical char- acteristics and outcomes of Nurse Practitioner managed outpatient induction and community induced transfers of buprenorphine/nalox-one treatment during pregnancy. Methods: A retrospective cohort analysis of patients managed by nurse practitioner and treated with buprenorphine/naloxone for opioid use disorder during pregnancy and their neonates. N=319 moth- er-neonate dyads were treated at the University of North Carolina Horizons’ Clinic between January 1, 2014 and May 31, 2018. N=51 mother-neonate dyads that underwent buprenorphine/naloxone induction via the Horizons’ Clinic protocol versus n=44 mother-ne- onate dyads that underwent community buprenorphine/naloxone induction via an outside provider and transferred to Horizons’ for pre- natal care and management of Medications for Addiction Treatment (MAT) during pregnancy were compared. Demographic data; maternal, fetal, and neonatal clinical characteristics; and clinical outcomes were collected via chart review. Results: No significant differences were found in maternal clinical characteristics between the two groups. Estimated Fetal Weight (EFW) percentile was the only significantly different fetal outcome with the Horizons’ induction group having a significantly higher mean EFW percentile compared to those who underwent community induction (41.8vs. 35.7, P=0.042). Finally, no significant differences in preterm birth or low birth weight were found between Horizons’ induction group and the North Carolina state averages. Conclusion: The induction protocol utilized by the UNC Horizons prenatal clinic shows similar safety and efficacy in pregnancy out comes compared to community induced transfers. The outcomes for both groups indicate relative safety and effectiveness of buprenor-phine/naloxone during pregnancy. Nurse practitioner prescribing and outpatient protocols could help expand access to MAT by providing more options for patients. outcome variables were meant to demonstrate safety and effectiveness for mother, fetus and neonate before, during and after pregnancy. Findings suggest that rates of normal anatomy ultrasound screenings, percentage of FHR within normal limits, gestational age at birth, birth weight in grams, 1 and 5 minute APGAR scores, new born days in nursery, and rates of NAS requiring medication inter vention during pregnancy do not differ significantly between patients who underwent the Horizons’ induction and those who underwent community induction. Remarkably, the only significant difference in outcomes was positive: patients in the Horizons’ induction group had significantly higher EFW percentile compared to those who under went community induction (41.8 vs. 35.7, P=0.042). EFW is a mea sure of normal fetal growth and can be a predictor for LBW. is an exciting finding due to the high incidence of low birth weight among patients This study shows that buprenorphine/naloxone has rela","PeriodicalId":87233,"journal":{"name":"Clinical obstetrics, gynecology and reproductive medicine","volume":"140 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76182115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}