Balkan Medical Journal最新文献

{"title":"Hypertensive Disorders of Pregnancy: Diagnosis, Management and Timing of Birth.","authors":"Cihan İnan, Lütfiye Uygur, Verda Alpay, Reyhan Ayaz, Nihal Şahin Uysal, Aydan Biri, Gökhan Yıldırım, Niyazi Cenk Sayın","doi":"10.4274/balkanmedj.galenos.2024.2024-7-108","DOIUrl":"10.4274/balkanmedj.galenos.2024.2024-7-108","url":null,"abstract":"<p><p>Hypertensive disorders of pregnancy are significant contributors to maternal and perinatal morbidity and mortality. The definition, classification, and management of these disorders have evolved over time. Notably, the disease classification enables caretakers to manage the disease as well as safeguard maternal and fetal health. The approach and management for pregnancies with gestational and chronic hypertension or pre-eclampsia with or without severe features should be adequately elucidated to mitigate adverse perinatal outcomes. This review aimed to present the most recent definition and classification of hypertensive disorders of pregnancy to address their management, determine the optimal timing of birth, and establish short- and long-term follow-up protocols following parturition.</p>","PeriodicalId":8690,"journal":{"name":"Balkan Medical Journal","volume":"41 5","pages":"333-347"},"PeriodicalIF":1.9,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142139166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Constrictive Pericarditis Associated with Long COVID, Its Vaccine, or Both?","authors":"Çağlar Kaya, Kenan Yalta","doi":"10.4274/balkanmedj.galenos.2024.2024-6-109","DOIUrl":"10.4274/balkanmedj.galenos.2024.2024-6-109","url":null,"abstract":"","PeriodicalId":8690,"journal":{"name":"Balkan Medical Journal","volume":" ","pages":"411-412"},"PeriodicalIF":1.9,"publicationDate":"2024-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent Schwannoma of the Cauda Equina: A Rare Diagnosis","authors":"Laura Gabriela Silva, Victor Sudário Takahashi, Marcelo de Queiroz Pereira da Silva, Márcio Luís Duarte","doi":"10.4274/balkanmedj.galenos.2024.2024-1-84","DOIUrl":"10.4274/balkanmedj.galenos.2024.2024-1-84","url":null,"abstract":"","PeriodicalId":8690,"journal":{"name":"Balkan Medical Journal","volume":" ","pages":"306-307"},"PeriodicalIF":1.9,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140100947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurobrucellosis Presenting with Tumor-Like Lesion and Vasculitic Involvement","authors":"Baran Serdar Sunal, Cihan Özgür, Çiğdem Deniz, Elif Altın","doi":"10.4274/balkanmedj.galenos.2024.2024-3-25","DOIUrl":"10.4274/balkanmedj.galenos.2024.2024-3-25","url":null,"abstract":"","PeriodicalId":8690,"journal":{"name":"Balkan Medical Journal","volume":" ","pages":"308-309"},"PeriodicalIF":1.9,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel Surgical Landmark to Identify the Recurrent Laryngeal Nerve","authors":"Yusuf Dündar, Cynthia M Schwartz, Micah Lierly, Tam Q Nguyen, Kerry K Gilbert, Drew H Smith, Nadia Tello, Joehassin Cordero","doi":"10.4274/balkanmedj.galenos.2024.2024-2-2","DOIUrl":"10.4274/balkanmedj.galenos.2024.2024-2-2","url":null,"abstract":"<p><strong>Background: </strong>Although several surgical landmarks have been proposed to localize the recurrent laryngeal nerve (RLN), there is still no reliable landmark.</p><p><strong>Aims: </strong>To validate the reliability of a novel reference point at the intersection of the inferior border of the cricopharyngeal muscle and the inferior cornu of thyroid cartilage for locating the RLN.</p><p><strong>Study design: </strong>Cadaver dissection study in the academic department of otolaryngology-head and neck surgery.</p><p><strong>Methods: </strong>Sixty-four RLNs in cadavers were assessed, and measurements of different surgical landmarks in conjunction with the proposed surgical landmark were obtained. Descriptive statistics, Pearson’s chi-squared test, and Student’s t-test were performed to analyze the data using GraphPad Prism (version 9.4.1; Dotmatics, Boston, Massachusetts, USA).</p><p><strong>Results: </strong>The average distance from the proposed landmark to the RLN was 2.3 ± 0.85 mm. The RLN was located just posterior to the reference point in 95.31% of the cadavers. The RLN passed under the inferior constrictor muscle in 90.63% of the cadavers. There was no statistically significant difference between right- and left-sided RLNs in terms of their relation with the reference point.</p><p><strong>Conclusion: </strong>The proposed reference point can be used as a reliable landmark to locate the RLN. This reference point may help surgeons during difficult thyroidectomy surgeries by providing an additional anatomical landmark.</p>","PeriodicalId":8690,"journal":{"name":"Balkan Medical Journal","volume":" ","pages":"280-285"},"PeriodicalIF":1.9,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141295435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography as a Valuable Diagnostic Tool in Patients with Ovarian Cancer and Its Correlation with Tumor Marker Cancer Antigen-125","authors":"Preslava Ilieva-Gabarska, Valeria Racheva","doi":"10.4274/balkanmedj.galenos.2024.2023-12-84","DOIUrl":"10.4274/balkanmedj.galenos.2024.2023-12-84","url":null,"abstract":"","PeriodicalId":8690,"journal":{"name":"Balkan Medical Journal","volume":" ","pages":"314-316"},"PeriodicalIF":1.9,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140100946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emerging Systemic Treatment Options in Atopic Dermatitis.","authors":"Andaç Salman, Ana M Giménez-Arnau","doi":"10.4274/balkanmedj.galenos.2024.2024-5-78","DOIUrl":"10.4274/balkanmedj.galenos.2024.2024-5-78","url":null,"abstract":"<p><p>Atopic dermatitis (AD) is a chronic inflammatory condition that significantly affects the quality of life of both patients and their families or caregivers. Recently, treatment for moderate-to-severe AD were limited to conventional immunosuppressive therapies. However, currently, with the approval of biologic treatments and oral small molecules in the past decade, the effective and safe management of patients with AD is possible. Despite these advancements, challenges and unmet needs in clinical practice remain. This includes patients who do not respond well to or cannot tolerate existing treatment options and inadequate therapies that can modify the disease course. This review aimed to provide an overview of the current treatment approach for AD, highlight the current challenges in treatment, and discuss the rationale for novel treatment options and emerging evidence on systemic treatment options for AD.</p>","PeriodicalId":8690,"journal":{"name":"Balkan Medical Journal","volume":"41 4","pages":"239-247"},"PeriodicalIF":1.9,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141533471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin C Levels in Pregnant Women and the Efficacy of Vitamin C Supplements in Preventing Premature Rupture of Membranes: A Systematic Review and Meta-Analysis","authors":"Ana V Pejcic, Nemanja Z Petrovic, Milan D Djordjic, Milos N Milosavljevic","doi":"10.4274/balkanmedj.galenos.2024.2024-2-79","DOIUrl":"10.4274/balkanmedj.galenos.2024.2024-2-79","url":null,"abstract":"<p><strong>Background: </strong>Premature rupture of membranes (PROM) is defined as the leakage of amniotic fluid before the onset of labor and delivery contractions. Some studies found that women who experienced PROM had significantly lower vitamin C blood levels than those who did not, while others found no significant differences. Previous systematic reviews and meta-analyses on the efficacy of vitamin C in the prevention of PROM had conflicting results.</p><p><strong>Aims: </strong>Conduct a systematic review and meta-analysis to determine if there was a significant difference in vitamin C blood levels in women who had PROM versus the control group who did not and to determine if vitamin C supplements could help prevent it.</p><p><strong>Study design: </strong>Systematic review and meta-analysis.</p><p><strong>Methods: </strong>We registered our protocol with PROSPERO (CRD42022371644). We searched PubMed/MEDLINE, Web of Science, and Scopus through February 15, 2024. Additionally, backward and forward citation searches were conducted. Studies were selected based on predetermined inclusion and exclusion criteria. Meta-Essentials: Workbooks for Meta-Analysis (version 1.5) was used for analysis.</p><p><strong>Results: </strong>Twenty-five studies (26 reports) met all eligibility criteria, with 18 studies (18 reports) assessing vitamin C levels and seven studies (eight reports) evaluating efficacy. Women with PROM, whether preterm or term, had significantly lower vitamin C levels [Hedges’ g, -1.48; 95% confidence interval (CI): -2.82, -0.14; <i>p</i> = 0.020; <i>I²</i> = 94.08%) and specifically preterm PROM after removing the outlying study [Hedges’ g, -1.29; 95% CI: -1.85, -0.73; <i>p</i> < 0.001; <i>I²</i> = 87.35%). Vitamin C supplementation significantly reduced the risk of preterm or term PROM [risk ratio (RR), 0.57; 95% CI: 0.39, 0.81; <i>p</i> < 0.001; <i>I²</i> = 12.17%), particularly for preterm PROM (RR, 0.67; 95% CI: 0.45, 0.99; <i>p</i> = 0.001; <i>I²</i> = 0.00%). There were no significant differences in vitamin C levels between women with term PROM and controls, and there were no differences in the risk of developing term PROM between women taking vitamin C supplements and controls. Results were not robust in all sensitivity analyses.</p><p><strong>Conclusion: </strong>Women with PROM, particularly those who developed it preterm, appear to have significantly lower vitamin C levels, and vitamin C supplementation appears to be effective in reducing the risk of PROM, particularly preterm PROM. More high-quality studies with low risk of bias, more homogenous, and larger samples are needed to confirm these findings.</p>","PeriodicalId":8690,"journal":{"name":"Balkan Medical Journal","volume":" ","pages":"248-260"},"PeriodicalIF":1.9,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588900/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141074359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human Monkeypox Proctitis","authors":"Yu Miyazaki, Takuya Adachi, Noriyuki Kuniyoshi, Yasuhiro Noda, Mami Nagashima","doi":"10.4274/balkanmedj.galenos.2024.2024-1-94","DOIUrl":"10.4274/balkanmedj.galenos.2024.2024-1-94","url":null,"abstract":"","PeriodicalId":8690,"journal":{"name":"Balkan Medical Journal","volume":" ","pages":"310-311"},"PeriodicalIF":1.9,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141070601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A One Health Approach to Zoonotic Diseases in Extraordinary and Ordinary Circumstances.","authors":"Hüseyin Güdücüoğlu","doi":"10.4274/balkanmedj.galenos.2024.2024-140624","DOIUrl":"10.4274/balkanmedj.galenos.2024.2024-140624","url":null,"abstract":"","PeriodicalId":8690,"journal":{"name":"Balkan Medical Journal","volume":"41 4","pages":"236-238"},"PeriodicalIF":1.9,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11588901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141533516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}