The Glaxo volume; an occasional contribution to the science and art of medicine最新文献

{"title":"THE INFLUENCE OF PHYSICAL THERAPY ON INDICATORS OF THE LOCOMOTIVE SYNDROME IN ELDERLY PERSONS WITH THE CONSEQUENCES OF TOTAL KNEE ARTHROPLASTY","authors":"Ch.V. Petruniv","doi":"10.21802/artm.2023.1.25.52","DOIUrl":"https://doi.org/10.21802/artm.2023.1.25.52","url":null,"abstract":"Objective: to evaluate the effectiveness of the developed physical therapy program on the parameters of the locomotive syndrome in elderly people with the motor consequences of total knee arthroplasty against the background of the geriatric syndrome of sarcopenia, in the remote period after the operation. \u0000Methods. 80 elderly people were examined. The control group consisted of 24 people without joint endoprostheses, with no signs of sarcopenia. The comparison group consisted of individuals with knee arthroplasty and sarcopenia with low rehabilitation compliance with regard to active rehabilitation intervention. Representatives of the main group with knee endoprosthesis and sarcopenia practiced according to a developed program of physical therapy, created taking into account the specifics of each comorbid condition. The program lasted 6 months; contained the following elements: therapeutic exercises, functional training, massage, kinesiotaping; dietary recommendations; patient education. Its purpose was: correction of the phenomena of motor stereotype violation as a consequence of total knee arthroplasty, in particular, phenomena of the locomotive syndrome, leveling of the phenomena of sarcopenia both at the level of its motor manifestations and at the level of etiopathogenesis of this geriatric condition; facilitation of activities of daily life, improvement of psycho-emotional state, and – as a result – improvement of quality of life. In the process of physical therapy, individual short- and long-term goals defined in the SMART format were consistently achieved within the framework of the patient-centered rehabilitation model. The effectiveness of the program was evaluated according to the dynamics of The Short Physical Performance Battery, Functional Gait Assessment, Fall efficacy scale, 25-question Geriatric Locomotive Function Scale. \u0000Results. In elderly patients with knee arthroplasty and sarcopenia, signs of locomotor syndrome were found in the form of impaired balance when performing simple movements (according to The Short Physical Performance Battery), violation of the normal gait stereotype and the resulting risk of falling (according to the Functional Gait Assessment), which led to awareness of the fear of falling (according to the Fall efficacy scale). The hall level of movement disorders corresponded to locomotive syndrome of the II degree (according to the 25-question Geriatric Locomotive Function Scale). The developed physical therapy program revealed a statistical improvement in the condition of patients due to the effect on the components of the locomotive syndrome due to the improvement of balance and gait parameters, reduction of the risk of falling and fear of falling compared to the initial indicators for all the studied parameters (р<0.05); however, the indicators of the control group were not reached (p>0.05). Low rehabilitation compliance in patients with knee arthroplasty and sarcopenia, despite awareness of the risks of","PeriodicalId":86625,"journal":{"name":"The Glaxo volume; an occasional contribution to the science and art of medicine","volume":"174 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83780534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ASSESSMENT OF ORTHOPEDIC TREATMENT LATE RESULTS OF PATIENTS WITH FIXED PARTIAL DENTURES DUE TO THE FUNCTIONAL STATE OF ABUTMENT TEETH","authors":"Yu.V. Klymyuk, Z. Ozhogan, M.I. Kyrylyuk","doi":"10.21802/artm.2023.1.25.33","DOIUrl":"https://doi.org/10.21802/artm.2023.1.25.33","url":null,"abstract":"The scientific work highlights the results of an index assessment of the periodontal condition of patients abutment teeth with dentition defects which were replaced with metal-ceramic fixed partial dentures due to partial teeth loss. Since during the preparation of abutment teeth there is sometimes a need for endodontic treatment of them due to medical indications, we investigated the state of the periodontium before, during and after treatment and compared index indicators of pulpless teeth with teeth in which the vascular-nerve bundle was preserved. It was established that the periodontium of the vital tooth recovers and functions much better in comparison with the surrounding dental tissues of a nonvital tooth. Where there are inflammatory changes, which are objectively caused by pronounced swelling and bleeding of the gingival papilla. It is caused due to rubber dam pressure, which in turn is confirmed by reliable data of index indicators determined in various the terms of the treatment. \u0000After conducting a detailed examination of patients with vital abutment teeth with defects in the hard tissues of the teeth, we found that in the age group of 30-39 years, the most common defect in the hard tissues of the teeth was caries damage, which was observed in 8 patients (72.7%), damage due to injuries was found in 2 patients (18.2%), enamel hypoplasia was found in 2 patients (18.2%). \u0000Treatment of partial adentia involves the preparation of abutment teeth followed by the manufacture of fixed bridge prostheses. However, the vitality of the abutment tooth should be taken into account and the reserve forces of the periodontium should be taken into account in order to prevent functional overload. It is also necessary to monitor the hygienic condition of the oral cavity during the treatment and at various times after its completion. \u0000The peculiarity of the proposed method of preparation of vital upper and lower abutment teeth consists in the creation of a champfer on the vestibular surface with the transition to an imitation of a champfer on the oral surface, under constant control of the thickness of the peripulpal dentin using a dentometer with the use of full water cooling and subsequent fixation of provisional crowns. The use of a complex of diagnostic techniques for full control of the effectiveness of treatment during and after prosthetics at different times is substantiated and proposed. \u0000The gnathodynamometric study was carried out using an advanced device, the VIZIR E1000 gnathodynamometer: the plates placed between the opposing teeth were bitten, as a result of which the load was digitized using a flexible connection through an analog-digital converter and displayed on the display of a computer program, displayed graphically in newtons (N), the time of the masticatory load was also recorded in seconds. \u0000Using data from clinical indices, it was determined that the preservation of vital teeth is a reliable criterion of the effectiveness of the us","PeriodicalId":86625,"journal":{"name":"The Glaxo volume; an occasional contribution to the science and art of medicine","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83604795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MORPHO-FUNCTIONAL CHARACTERISTICS OF THE TESTICLES OF MEN WITH DIFFERENT FORMS OF PATHOSPERMIA","authors":"","doi":"10.21802/artm.2023.1.25.12","DOIUrl":"https://doi.org/10.21802/artm.2023.1.25.12","url":null,"abstract":"The most difficult form of male infertility to treat is azoospermia. It is identified as a complete absence of sperm in the ejaculate. Depending on the nature and causes of impaired spermatogenesis, azoospermia is divided into obstructive (excretory, OA) and non-obstructive (secretory, NOA). Testicular biopsy is the most effective method of diagnosis and a component of possible treatment for azoospermia. It is the only objective method of differential diagnosis between non-obstructive and obstructive forms of azoospermia. The aim: histological analysis of testicular biopsies of men with various forms of azoospermia. Мaterials and Methods. 78 infertile men with azoospermia were examined. They were divided into two groups: the first group, men with NOA (n = 28); the second group, men with OA (n = 50). The biopsy was preceded by a mandatory ultrasound diagnosis of the portal system. The biopsy was performed using the method of open operative access. Biopsies were mostly taken from the more palpable testicle or from both testicles. Biopsies were fixed in buffered 10% formalin (pH 7.2). After 1 day, they were dehydrated in 70% ethanol and embedded in paraffin. For histological studies, sections with a thickness of 5 μm were stained with hematoxylin and eosin. Biopsies were evaluated in accordance with previously described methods. Results. Histological analysis of testicular biopsies from 28.7% of patients with a non-obstructive form of azoospermia showed swelling of the testicular stroma, destructive changes in testosterone-producing cells, disruption of the structure of the syncytial complexes of the spermatogenic epithelium, and the complete absence of the process of spermatogenesis in individual tortuous seminiferous tubules, the absence of contacts between sustentocytes, and in erythrocyte sludge in the lumen of vessels. 42.8% of patients had fibrosis of the testicular stroma, stroma swelling, thinning of the wall of convoluted seminiferous tubules, violation of the structure of the syncytial complexes of the spermatogenic epithelium, proliferation of the wall of the convoluted seminiferous tubules into their lumen, and infiltration of the testicular stroma with lymphocytes. In 54.0% of patients with preserved spermatogenesis and an obstructive form of azoospermia, it was possible to find a history of orchoepididymitis in the anamnesis; one patient (2.0%) underwent bilateral orchopexy at the age of 5 years due to cryptorchidism; 6.0% recalled the trauma calculi in the anamnesis; and 38.0% denied any factors affecting fecundity in the anamnesis. Conclusions. The non-obstructive form of azoospermia is characterized by the following parameters: mostly a violation of the structure of the spermatogenic epithelium, a complete absence of the process of spermatogenesis in individual convoluted seminiferous tubules, a violation of the structure of the hematotesticular barrier, and a violation of blood microcirculation. The histological picture of ","PeriodicalId":86625,"journal":{"name":"The Glaxo volume; an occasional contribution to the science and art of medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76217865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE EFFECT OF POSTPARTUM PHYSICAL THERAPY ON AUTONOMIC SYMPTOMS OF POST-COVID-19 SYNDROME IN WOMEN AFTER CAESAREAN SECTION WHO EXPERIENCED CORONAVIRUS DISEASE DURING PREGNANCY","authors":"","doi":"10.21802/artm.2023.1.25.6","DOIUrl":"https://doi.org/10.21802/artm.2023.1.25.6","url":null,"abstract":"Purpose: to determine the effectiveness of restoring the state of women health with post-COVID-19 syndrome who underwent cesarean section, based on the dynamics of parameters of the autonomic nervous system. \u0000Methods. 44 women were examined at the beginning of the late postpartum period. The control group consisted of 15 women who gave birth vaginally and did not suffer from COVID-19 during pregnancy and observation. The comparison group consisted of 15 women after cesarean section who suffered from COVID-19 during pregnancy, recovered during pregnancy and the postpartum period according to general recommendations for the rehabilitation of patients with coronavirus infection. The main group consisted of 14 women after caesarean section, suffered from COVID-19 during pregnancy, performed a proven program of physical therapy for 2 months using breathing therapeutic exercises, therapeutic exercises with elements of yoga for the muscles of the back, abdomen, upper and lower limbs, taking into account movement limitations due to a scar of the anterior abdominal wall; massage of the chest, back, abdomen; aromatherapy sessions; autogenic training sessions. They tried to restore the state of women through a balance between the sympathetic and parasympathetic departments due to the normalizing effect of the applied agents on the hormonal background and psycho-emotional state, reducing the feeling of bodily discomfort, general strengthening of the body, accelerating the recovery of the organs of the abdominal cavity and pelvis, accelerating adaptation to changes in habitual activity due to a violation daily routine and childcare needs. The condition of the women was assessed by the results of the test with isometric load, the Kerdo index, the dynamics of 24-hour heart rate variability monitoring (power in the range of low LF frequencies and high HF frequencies, LF/HF ratio, Baevsky tension index). \u0000Research results. During the first examination, an imbalance between the activity of the sympathetic and parasympathetic links of the autonomic nervous system towards sympathicotonia was detected in all women, which was most pronounced in women with post-COVID-19 syndrome in all parameters. During re-examination, the best result in terms of all studied parameters was found by women of the control group, who demonstrated the dynamics of the normal course of the postpartum period after vaginal delivery and increased activity of the parasympathetic department against the background of suppression of the sympathetic department. The results of the women of the main group according to the Kerdo index, tests with isometric tension, the results of daily blood pressure monitoring, which were determined, were statistically significantly better than those of the women of the comparison group, testifying to the reduction of the imbalance of the links of the autonomic nervous system and the advantages of the rehabilitation program for the correction of the autonomic signs of","PeriodicalId":86625,"journal":{"name":"The Glaxo volume; an occasional contribution to the science and art of medicine","volume":"128 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88235972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MANIFESTATIONS OF THE POST-COVID SYNDROME IN THE ORAL CAVITY","authors":"H.V. Kindrat, V.Y. Kateryniuk, O. Repetska, M. Rozhko, I. Kindrat","doi":"10.21802/artm.2023.1.25.29","DOIUrl":"https://doi.org/10.21802/artm.2023.1.25.29","url":null,"abstract":"Corona virus infection currently remains a key question giving new and new strains. The disease itself has a multisymptomatic course, in which various organs and systems are affected. The oral cavity is no exception. For dentists, it becomes an important task to detect lesions of the oral cavity at various stages of the disease development and during the so-called recovery period, to increase the effectiveness of treatment and, if necessary, to refer the patient to narrow specialists: a neuropathologist, psychologist or other doctor in order to develop rehabilitation measures. \u0000The aim is to study the manifestations of post-covid syndrome in the oral cavity. \u0000Materials and methods. On the basis of the Department of Dentistry of the National Institute of Scientific Research of the IFNMU, as part of the advisory assistance for diseases of the oral cavity, in the period from 2021 to 2022, an examination of 33 patients who suffered from a coronavirus disease of varying degrees of severity was carried out. These patients were referred for consultation from private dental institutions, dental polyclinics in the city of Ivano-Frankivsk and the region. A significant part of patients sought help online. Clinical research methods included collection of complaints, anamnesis of the disease, analysis of extracts of medical histories from medical institutions. The dental examination was carried out according to the generally accepted scheme: examination of the oral cavity, in particular, the condition of the mucous membrane (color, moisture, presence of pathological formations), the condition of the periodontal tissues, oral hygiene, hard tissues of the teeth, orthopedic structures, traumatic factors, bad habits were evaluated. \u0000Research results. Results of the study Based on the results of the examination of the patients, we diagnosed a number of pathological conditions of the oral cavity, which included candidal stomatitis (glossitis) and they accounted for 30% of the examined, lichen planus - 30% of cases. These are the persons who were hospitalized for a covid disease. In the rest of the patients who suffered from the disease in a mild form, periodontal tissue damage was noted in 25%, the presence of aphthous rashes in 15% of cases. From the number of people examined, we observed combined pathologies in 5 people: candidiasis, ChPL and glossitis or gingivitis (periodontitis) and aphthae. Microscopic examination of smears from the oral cavity indicates a significant number of fungi of the genus Candida, provided that there is no bacterial flora, that is, dysbacteriosis was observed. Having analyzed the prevalence of pathological conditions of the oral cavity in the examined patients, the tendency of the formation of candidal stomatitis in patients on the background of antibiotic therapy of pneumonia is followed. The development of lichen planus, which the patients had not observed before, is a consequence of stress and shock during the illness. \u0000Conclusions","PeriodicalId":86625,"journal":{"name":"The Glaxo volume; an occasional contribution to the science and art of medicine","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75988145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FORENSIC-MEDICAL EVALUATION OF INJURIES RECEIVED DURING OPERATION OF PERSONAL MOBILITY DEVICES: THE STATE OF THE PROBLEM (REVIEW)","authors":"Yu. Z. Kotsyubynska, N. Kozan, V.M. Kharevych, V.I. Lyampel, O.Yu. Mickanyuk","doi":"10.21802/artm.2023.1.25.106","DOIUrl":"https://doi.org/10.21802/artm.2023.1.25.106","url":null,"abstract":"The article analyzes literature data on modern aspects of traffic injury. Some factor criteria for traffic injury are singled out and identified how they have changed with the modernization of modern vehicles. Тhe data concerning injuries associated with the use of modern personal mobility devices, such as kick-scooters, electric scooters, electric unicycles, electric hover boards, skateboards, roller skates and similar devices were analyzed. Prospects for studying this problem and its value for modern forensic traumatology are outlined. Traffic injury is one of the most common problems today, as it is one of the main causes of death of the young population and ranks first among the causes of death due to injury. In particular, on the territory of Ukraine, the number of killed in car accidents each year reaches 400,000. Тhis scientific research was carried out with the aim of conducting an analysis of literary assets on the problem of studying car injuries associated with the operation of modern electric means of personal mobility. Due to new technological features of modern vehicles, the appearance of new types of transportation facilities, such as kick-scooters, electric scooters, electric unicycles, electric hover boards, skateboards, roller skates and similar devices, except for traditional issues, answers to which are widely covered in the fundamental works of the last century, new questions are posed to the experts, conditioned new, previously undescribed signs of traffic injury the requirements to the level of the scientific validity of the expert's conclusions are growing, which require appropriate methods of expert research. However, despite the full range of data provided, the problem associated with the study of injuries received on kick-scooters, electric scooters, electric unicycles, electric hover boards, skateboards, roller skates and similar devices is little studied. This type of vehicle was first introduced in November 2017 and become quite common today. The main task of this type of vehicle is to facilitate travel in large cities. Despite the ease and accessibility of operation, this type of transport is quite fast and can pose a danger to drivers and other road users. Therefore, forensic experts received new challenges today related to the study of the complex of injuries in drivers and pedestrians resulting from the operation of electric scooters, the mechanism of their formation, the study of signs of characteristic injuries to the driver and pedestrians’ data. However, despite all the work done, its results in most cases are statistical in nature and do not provide a comprehensive picture of the mechanism of injury and forensic-medical evaluation of the consequences of injury. There is also an open question related to the study of the characteristic’s injuries of drivers and pedestrians, the establishment of differential traumatic criteria specific to the driver and pedestrians. There is also an open question related to the","PeriodicalId":86625,"journal":{"name":"The Glaxo volume; an occasional contribution to the science and art of medicine","volume":"93 11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87658501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE INFLUENCE OF SMOKING ON INDICATORS OF LIPID PEROXIDATION AND OXIDATIVE MODIFICATION OF PROTEINS IN THE ORAL FLUID IN TEENAGERS AND YOUNG ADULTS","authors":"","doi":"10.21802/artm.2023.1.25.44","DOIUrl":"https://doi.org/10.21802/artm.2023.1.25.44","url":null,"abstract":"Резюме. Встановлено, що паління впливає на слизову оболонку ротової порожнини, як безпосередньо, так і опосередковано – токсичні речовини потрапляють із током крові в слинні залози і виділяються з слиною в ротову порожнину. Зміни показників ротової рідини при цьому - компонентів антиоксидантно-прооксидантної системи, окисної модифікації білків, можуть бути першими ознаками розвитку стоматологічних захворювань. \u0000Мета – вивчити стан інтенсивності перекисного окиснення ліпідів та окисної модифікації білків у ротовій рідині під впливом паління в осіб підліткового та юнацького віку. \u0000Матеріали та методи. Проведено вивчення біохімічних показників (перекисного окиснення ліпідів, перекисного окиснення білків) ротової рідини у 114 осіб підліткового та юнацького віку від 15 до 24 років, яких розділено на групи: у І групу включили 26 осіб, що палять традиційні сигарети; у ІІ групу – 22 особи, що палять електронні сигарети (Вейпи); у ІІІ групу – 23 особи, що палять пристрої для нагрівання тютюну (IQOSи); у ІV групу – 43 особи, що не палять. \u0000Результати. Оцінка стану перекисного окиснення білків у ротовій рідині учасників спостереження за даними рівня ТБК-АП та дієнових кон’югантів засвідчила наявність вірогідної різниці між показниками в осіб підліткового та юнацького віку, що мають шкідливу звичку та осіб, що не палять. При порівнянні змін показників різних фракцій окисної модифікації білків в осіб, що мають шкідливу звичку і осіб, що не палять було встановлено, що найбільше зростають показники альдегідо- та кетонопохідні динітрофенолгідразону основного характеру – ОМБ 430 та ОМБ 530. \u0000Висновки. У осіб підліткового та юнацького віку, що палять відбуваються зміни біохімічних показників ротової рідини, а саме спостерігається посилення процесів перекисного окиснення ліпідів - визначається підвищенням показника ТБК-АП, рівня дієнових конюгатів та збільшення концентрації продуктів окисної модифікації білків.","PeriodicalId":86625,"journal":{"name":"The Glaxo volume; an occasional contribution to the science and art of medicine","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82873586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ANALYSIS OF THE CLINICAL EFFECTIVENESS OF LOCAL ANESTHESIA IN THE TREATMENT OF ACUTE FORMS OF CARIES AND PULPITIS IN ADOLESCENTS","authors":"","doi":"10.21802/artm.2023.1.25.37","DOIUrl":"https://doi.org/10.21802/artm.2023.1.25.37","url":null,"abstract":"Local anesthesia in dentistry, as a way to block the pain syndrome, is one of the most common procedures at a dental appointment, and local anesthetics are among the most frequently used drugs in the daily practice of a dentist. In many cases, treatment is impossible without following most modern protocols. Painful sensations limit the volume of therapeutic measures and reduce the quality of treatment. In addition, the pain that a child may feel during a visit to the dentist leads to refusal of treatment and creates a fear of visiting doctors of any specialty. The child's behavior is controlled by emotions, which increase the physiological intolerance of pain in children. The doctor must help the patient get rid of the feeling of fear, create a situation of safety and painlessness during the examination and treatment. The peculiarities of the body in different age periods should be the basis of differentiated dental care for children. \u0000The effectiveness of anesthesia in teenagers largely depends on the patient's level of basic anxiety, these factors are directly dependent. \u0000The aim of the study. To determine the effectiveness of local anesthesia in the treatment of acute medium caries, acute deep caries and acute pulpitis in adolescents with different levels of basic anxiety. \u0000Materials and methods. Patients aged 11 to 17 years were selected for analysis, in particular, 126 cases of acute medium caries (55 on the upper jaw and 71 on the lower), 128 cases of acute deep caries (63 on the upper jaw and 65 on the lower) and 98 cases of acute pulpitis (42 teeth on the upper jaw and 56 on the lower). All pathologies required treatment under local anesthesia. Dental pathologies were verified according to the main diagnostic criteria. \u0000Drugs belonging to the group of substituted acetanilide amides were used as local anesthetics. \u0000In all patients, the level of reactive and personal anxiety was assessed according to the method of Ch.D. Spielberger (adapted by Yu.L. Khanin). \u0000Statistical analysis of the obtained data was carried out on a personal computer using licensed programs ˝MS Excel 7˝ for the operating system˝ Windows˝ and the standard program package \"STATISTICA\" v. 6.0. \u0000All participants were informed about the goals, organization, methods of the study and signed an informed consent to participate in it, and all measures are taken to ensure patient anonymity. \u0000Conclusions. In teenagers, pain during the treatment of dental diseases, such as acute caries or acute pulpitis, is directly proportional to the severity of the pathology and the level of basic anxiety of the individual. \u0000In the treatment of acute forms of medium and deep caries and pulpitis, a significant decrease in the percentage of pain syndrome intensity was observed in all clinical groups, however, in the group with a low level of anxiety, 100% disappearance of pain syndrome was noted in all patients after 15 minutes. \u0000In adolescents with a high level of anxiety, the reduction in the in","PeriodicalId":86625,"journal":{"name":"The Glaxo volume; an occasional contribution to the science and art of medicine","volume":"122 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74289824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"INCIDENCE OF UTERINE SARCOMA IN IVANO-FRANKIVSK REGION","authors":"S. S. Davydiuk, A. Kryzhanivska","doi":"10.21802/artm.2022.4.24.33","DOIUrl":"https://doi.org/10.21802/artm.2022.4.24.33","url":null,"abstract":"Uterine sarcoma (US) is a rare disease characterized by an aggressive course and poor prognosis, accounting for 3–7% of malignant neoplasms of the uterus. \u0000The goal. Study the incidence of uterine sarcoma in Ivano-Frankivsk region and to analyze the clinical and morphological characteristics of the tumor. \u0000Materials and methods. Our research is based on clinical observations at the Municipal Non-Profit Institution “Precarpathian Clinical Oncology Center of the Ivano-Frankivsk Regional Council” for the period from 2010 to 2021. \u0000The results. The analyzed data showed that the number of patients with uterine sarcoma was: stage I – 51.61%, stage II – 25.8%, stage III – 6.45%, and stage IV – 16.15%. Special attention should be paid to the observation of 48 patients with stages I, II uterine sarcoma (pT1-2NOMO). \u0000The peak incidence of uterine sarcoma in women is observed in the age group of 40-59 years (60.4%). \u0000The most common histological type is leiomyosarcoma, which accounts for 66.67%. Due to the different pathogenesis of the development of mesenchymal tumors, their clinical characteristics also differ. Leiomyosarcoma of the uterus is most often detected in the age group of 40-59 years (43.75%), but for endometrial stromal sarcomas, the peak incidence falls on the age group of 50-81 years, and it is 22.9%. \u0000In patients with leiomyosarcoma stage I, the distribution of histological grading is almost the same for G1, G2 – 28.1% and 25%. In stage II leiomyosarcoma, G2 prevails – 18.75%. For endometrial stromal sarcoma, in contrast to leiomyosarcoma, G3 prevails for stage I and II, which is 38% and 25%, respectively. \u0000In most patients with uterine sarcoma, an unencumbered oncology history was observed. Indicators of tumor markers (CA125, REA) for most patients with stage I-II uterine leiomyosarcoma were normal, for 66.67%. \u0000Conclusions. Most often, uterine sarcoma occurs in women of perimenopausal and menopausal age; the peak incidence of uterine leiomyosarcoma is in the age group of 40-59 years. The peak incidence in women with endometrial stromal sarcoma was observed in the age group of 50-81 years. Most cases are diagnosed at stage I of the disease, and the most common histological type of all uterine sarcomas is leiomyosarcoma. Endometrial stromal sarcoma is the second histological type of spreading, which in world practice demonstrates the advantage of detecting a low degree of malignancy G1-2. In our clinical study, in stages I-II, the frequency of detection, corresponding to the degree of tumor differentiation, G3 prevails. Among patients with stage I leiomyosarcoma, women with normal BMI prevailed (20.83%); with stage II, women with excess body weight and obesity (Class III) prevailed, which amounted to 25%. The majority of patients with stage I endometrial stromal sarcoma had excessive body weight, which amounted to 36.4%. Women with obesity of Class I predominated in stage II endometrial stromal sarcoma – 27.3%. Non-aggravated oncology histor","PeriodicalId":86625,"journal":{"name":"The Glaxo volume; an occasional contribution to the science and art of medicine","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75577047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FEATURES OF FINGER DERMATOGLYPHICS IN MEN PRONE TO SEXUAL CRIMES","authors":"H. Zelenchuk, N. Kozan","doi":"10.21802/artm.2022.4.24.58","DOIUrl":"https://doi.org/10.21802/artm.2022.4.24.58","url":null,"abstract":"The article presents the data obtained during the study of the finger dermatoglyphs of persons who have committed sexual crimes, since there are currently no scientific works that would reflect the relationship between the manifestations of the phenotype (in particular, dermatoglyphic signs) in persons prone to crimes of the specified type. \u0000The aim of the study is to determine the complex of dermatoglyphic parameters of the fingers that make up the dermatoglyphic constitution of persons who have a propensity for sexual crimes (rape). \u0000Material and methods. Two groups of persons were studied: 1st group – corpses of persons who committed sexual crimes (50 persons); 2nd group - persons of the control group (50 persons). \u0000Research methods: dermatoglyphic, statistical analysis. \u0000Results. It was established that the frequency of radial loops on the left hand was 59.60% in rapists against 22.67% in CG, on the right - 56.80% against 19.56%, respectively; of ulnar loops - 3.20% versus 37.78% on and 3.60% versus 40.00% on the left, the frequency of arcs - 14.40% versus 4.44% on the left and 12.00% versus 5.33% on the left Rapists had radial loops on the first fingers of the left and right hands most often - 44.00% and 42.00%, respectively, curls (26.00% and 38.00%) and complex patterns (22.00% and 18.00%) ), ulnar loops – in 2.00% on both hands, arcs – in 6.00% on the left hand and did not occur on the right; on the II fingers of the arc - 34.00% on the left and 32.00% on the right hands, radial loops (30.00% 24.00%) and curls (20.00% 26.00%), ulnar loops (8, 00% and 10.00%), complex patterns (8.00% each); on the III finger - radial loops (68.00% and 70.00%) and arcs (18.00% on both hands), spiral patterns (10.00% and 4.00%), ulnar loops and complex patterns on 2.00%; radial loops (72.00% and 70.00%) and spiral patterns (16.00% and 24.00%) were most often found on the IV fingers of both hands, other patterns - 2.00% each; on V finger radial loops 84.00% and 78.00%, other patterns - from 2.00% to 8.00%. In CG, ulnar loops were most often found on I, III and V fingers of both hands (35.56%, 40.00% and 53.55%), and on II, IV – spiral patterns (33.33% and 47.78% ) and ulnar loops (30.00% and 35.55%); there were no arcs on IV and V fingers. A statistically significantly higher number of radial loops in rapists than in CG men was established on the fingers of both hands except for II, arcs except for III, a smaller number of ulnar loops on all fingers of both hands and curls on IV and V fingers (p < 0, 01). \u0000Conclusions. In the course of the study, the presence of phenotypic (dermatoglyphic) signs characteristic of persons prone to sexual crimes was established: \u0000 \u0000The structure of digital dermatoglyphics is dominated by radial loops, rarely complex patterns and ulnar loops. \u0000The peculiarities of homolateral symmetry were revealed: mostly there are 2-3 types of patterns in various combinations; radial loops prevail on the I fingers of both hands, arcs and compl","PeriodicalId":86625,"journal":{"name":"The Glaxo volume; an occasional contribution to the science and art of medicine","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82609911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}