Australasian Journal of Dermatology最新文献

{"title":"Factors Influencing the Use of Shave Biopsy for Lesions Suspicious of Melanoma in Australia: An Exploratory Mixed-Methods Study","authors":"Daniel Lindsay,&nbsp;Louisa G. Collins,&nbsp;Catherine M. Olsen,&nbsp;Nirmala Pandeya,&nbsp;David C. Whiteman,&nbsp;Luke Bookallil,&nbsp;Andrea McMurtrie,&nbsp;Lena von Schuckmann","doi":"10.1111/ajd.14411","DOIUrl":"10.1111/ajd.14411","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Recent Australian trends indicate that shave biopsies for diagnosing lesions suspicious of melanoma are increasing, yet reasons for this remain relatively unknown. We sought to understand which factors influence Australian clinicians' use of shave biopsy for managing thin lesions suspicious of melanoma in sites of low cosmetic sensitivity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We used a convergent, exploratory mixed-methods design, with a cross-sectional online survey (<i>n</i> = 59) and semi-structured qualitative interviews (<i>n</i> = 15). We recruited clinicians working in skin cancer medicine across Australia, mostly general practitioners (&gt; 80%) with some dermatologists (<i>n</i> = 7 survey and <i>n</i> = 1 interview participant). Survey participants indicated how frequently they used shave biopsies and rated the importance of factors when considering the use of a shave biopsy. Interview participants elaborated on the motivating factors for using different biopsy techniques. Qualitative data were professionally transcribed and analysed with content analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Most survey participants (95%) reported that identifying fewer signs of locally advanced melanoma was ‘very important’ for using shave biopsy. Fifty per cent of survey participants also reported that faster procedure speed and greater convenience were ‘very important’ reasons for using shave biopsy. Procedure speed was particularly important for using shave biopsy among clinicians self-identifying as time-poor. Interview participants noted (a) the risk of transecting the lesion base or (b) incomplete lesion removal from shave biopsies as reasons against their use.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The relative speed and convenience of shave biopsies in clinical practice are strong motivators for their use. Further evidence on patient outcomes with widespread use of shave biopsy is required to inform clinical guidelines.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 1","pages":"e1-e9"},"PeriodicalIF":2.2,"publicationDate":"2025-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Efficacy and Safety of Non-Biologic and Biologic Treatments in Palmoplantar Pustular Psoriasis and Palmoplantar Pustulosis: A Systematic Review and Network Meta-Analysis","authors":"Khalid M. Alshareef,&nbsp;Amal H. Abualola,&nbsp;Esraa A. Shaheen,&nbsp;Abdulaziz A. Aljuaid,&nbsp;Faisl Alshibi,&nbsp;Renad Kalantan,&nbsp;Bader Bashrahil,&nbsp;Dhaifallah H. Alghowairi,&nbsp;Awadh M. Alamri","doi":"10.1111/ajd.14410","DOIUrl":"10.1111/ajd.14410","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <p>Palmoplantar pustular psoriasis (PPPP), or palmoplantar pustulosis (PPP), is a type of psoriasis that affects the skin on the palms and soles. It is characterised by dermatosis and small sterile pustules and is considered a significant burden on patients' quality of life, as there is currently no gold standard treatment or cure. This network meta-analysis (NMA) compares the efficacy and safety of biologic and non-biologic medications for PPPP and PPP. Medline, Embase and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched. The efficacy and safety of all medications were assessed through a frequentist NMA using a random-effects model. Treatments were ranked using the net rank function, yielding P scores. Fourteen RCTs with 1056 participants were included. Guselkumab 100 mg was the most effective for improving PPPGA scores (<i>p</i> = 0.72, RR = 1.31, CI: 0.31–5.57). Guselkumab 100 mg was ranked the highest for achieving PPPASI-75 (RR = 5.4, CI: 1.26–23.2, <i>p</i> = 0.023). Oral cyclosporine 1 mg/kg/day was ranked the highest for PPPASI-50 (RR = 2.10, CI: 0.65–6.82). Etretinate 1 mg/kg/day had the highest rate of adverse events (RR = 1.78, CI: 0.92–3.44). Secukinumab 300 mg was associated with the highest rate of serious adverse events (RR = 1.58, CI: 0.21–12.02). Based on the P-scores from our NMA, guselkumab 100 mg was the most effective for PPPGA improvement, guselkumab 100 mg for PPPASI-75, oral cyclosporine 1 mg/kg/day for PPPASI-50, etretinate 1 mg/kg/day had the most adverse events, and secukinumab 300 mg was associated with the highest rate of serious adverse events.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>PROSPERO registration number: CRD42023460842</p>\u0000 </section>\u0000 </div>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 2","pages":"53-60"},"PeriodicalIF":2.2,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142943454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential Predictors of Biological Therapy Intensification in Moderate-To-Severe Hidradenitis Suppurativa: A Multicentre Study","authors":"Francisco Javier Melgosa Ramos,&nbsp;Ramón García Ruiz,&nbsp;Antonio Martorell","doi":"10.1111/ajd.14412","DOIUrl":"10.1111/ajd.14412","url":null,"abstract":"<div>\u0000 \u0000 <p>Moderate-to-severe hidradenitis suppurativa (HS) is a debilitating disease that often requires biological therapy. Despite the effectiveness of approved doses, some patients experience partial or loss of response over time, leading to the need for dose intensification. This retrospective multicentre study aimed to identify predictors of biological therapy intensification in HS patients. The results showed that prior use of biological treatments and biosimilar adalimumab were significant predictors of intensification, suggesting closer monitoring may be needed for certain patient profiles to optimise treatment outcomes.</p>\u0000 </div>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 2","pages":"e35-e38"},"PeriodicalIF":2.2,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142943451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of Switching From Intravenous to Subcutaneous Infliximab for Psoriasis: A Case Series","authors":"Conor Larney,&nbsp;Peter Foley,&nbsp;Kurt Gebauer,&nbsp;Benjamin S. Daniel","doi":"10.1111/ajd.14409","DOIUrl":"10.1111/ajd.14409","url":null,"abstract":"","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 2","pages":"e49-e51"},"PeriodicalIF":2.2,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142909178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-Stage Reconstruction of Large Scalp Surgical Defects With Exposed Bone Using Matriderm Flex and Full-Thickness Skin Grafts, a Case Report","authors":"Pedro Gil-Pallares,&nbsp;Manuel Almenara-Blasco,&nbsp;Alba Navarro-Bielsa,&nbsp;Yolanda Gilaberte","doi":"10.1111/ajd.14405","DOIUrl":"10.1111/ajd.14405","url":null,"abstract":"<p>The reconstruction of full-thickness scalp defects with exposed bone can be challenging. A single-stage reconstruction could be the preferred option for patients with multiple comorbidities. We propose using a dermal regeneration template (Matriderm Flex) and full-thickness skin grafts. The approach shown in this case report allows for quick healing, less donor-site discomfort in comparison with dermatome-harvested skin grafts, and very good aesthetic results, matching the surrounding skin thickness.</p>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 1","pages":"25-26"},"PeriodicalIF":2.2,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajd.14405","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermoscopy of Scabies: Utility of Polarised and Ultraviolet-Induced Fluorescence Examination in Fair and Dark Skin","authors":"Enzo Errichetti,&nbsp;Noemi Plozner,&nbsp;Nkechi A. Enechukwu,&nbsp;Yasmeen J. Bhat,&nbsp;Paweł Pietkiewicz,&nbsp;Natalia Salwowska,&nbsp;Iris Zalaudek,&nbsp;Giuseppe Stinco","doi":"10.1111/ajd.14406","DOIUrl":"10.1111/ajd.14406","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Ultraviolet-based dermoscopy may support the recognition of scabies, yet neither accuracy analyses nor data on skin of colour are available. The aim of this multicentric observational retrospective was to investigate the diagnostic accuracy of polarised and ultraviolet-induced fluorescence (UVF) dermoscopic examination in both fair and dark skin, also assessing possible differences according to the skin tone.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Consecutive patients with a diagnosis of scabies were eligible. All the images were randomly evaluated by two independent experienced investigators to identify scabietic findings reported in the literature. Interobserver agreement was evaluated for both polarised and UVF dermoscopic pictures through Cohen's kappa coefficient, while Fisher's exact test with <i>p</i>-value set at 0.05 was used for comparative analyses between the two settings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 97 lesions from 43 patients (21 with fair skin and 22 with dark skin) were included. The comparative analysis highlighted a superiority of UVF dermoscopy to detect the burrow (<i>p</i> = 0.003) and scabietic eggs (<i>p</i> = 0.012) in skin of colour, while polarised dermoscopy was more accurate to show the mite in fair skin (<i>p</i> = 0.042). Additionally, a general higher accuracy of both settings in light phototypes was also found, with a higher prevalence (<i>p</i> &lt; 0.05) of typical scabietic findings (i.e., serpiginous white tract, ‘triangle’ sign and grey-brown outlines of the burrow for polarised dermoscopy and green dot for UVF dermoscopy) compared to dark skin. Kappa values were 0.87 and 0.83 for polarised and UVF-dermoscopy, respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>UVF dermoscopy improves the recognition of scabies, though it should be considered complimentary to polarised light dermoscopic examination to increase diagnostic performance.</p>\u0000 </section>\u0000 </div>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 2","pages":"69-74"},"PeriodicalIF":2.2,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/ajd.14406","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Epididymo-Orchitis as an Adverse Effect of MMR Vaccine in Wart Immunotherapy","authors":"Abhishek Bhagwat,&nbsp;Varun Bansal,&nbsp;Shailija Pandita,&nbsp;Manju Daroach","doi":"10.1111/ajd.14404","DOIUrl":"10.1111/ajd.14404","url":null,"abstract":"","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 1","pages":"e32-e34"},"PeriodicalIF":2.2,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Grenz Ray Therapy for Darier Disease and Hailey-Hailey Disease: A Case Series of Three Patients","authors":"Conor Larney,&nbsp;Dale Jobson,&nbsp;Michael Webster","doi":"10.1111/ajd.14407","DOIUrl":"10.1111/ajd.14407","url":null,"abstract":"","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 1","pages":"e28-e31"},"PeriodicalIF":2.2,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Dermatological Practice Through Photography: Essential Techniques and Tools","authors":"Ishana Dixit,&nbsp;Elizabeth Dawes-Higgs","doi":"10.1111/ajd.14408","DOIUrl":"10.1111/ajd.14408","url":null,"abstract":"<div>\u0000 \u0000 <p>Clinical photography plays a crucial role in dermatology by aiding in diagnosis, monitoring treatment progress and providing valuable visual documentation for research and patient education. This article outlines key photographic techniques, equipment options and best practices tailored for dermatologists to improve clinical outcomes through high-quality imagery.</p>\u0000 </div>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 1","pages":"21-24"},"PeriodicalIF":2.2,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142880915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Persistent urticarial eruption preceding systemic features of adult-onset Still's disease: A case report","authors":"Amreeta Kaur BBiomed (Hons), MD,&nbsp;Mathuja Bavanendrakumar BSc, MBBS, FRACP,&nbsp;Shereen Oon MBBS, BMedSci, FRACP, PhD,&nbsp;Emma Veysey MBChB, MRCP, MPH, FACD","doi":"10.1111/ajd.14397","DOIUrl":"10.1111/ajd.14397","url":null,"abstract":"<p>Adult-onset Still’s disease (AOSD) is a rare autoinflammatory systemic disorder classically characterised by inflammatory polyarthritis, daily fevers and a transient asymptomatic salmon-pink maculopapular rash that typically arises with the onset of fevers. We report a case of AOSD presenting with a severely pruritic urticarial eruption starting 6 weeks prior to the onset of fever and arthritis and complicated by macrophage activation syndrome. This case highlights the importance of early recognition of diverse cutaneous manifestations of AOSD to facilitate timely diagnosis and treatment to improve disease outcomes.</p>","PeriodicalId":8638,"journal":{"name":"Australasian Journal of Dermatology","volume":"66 2","pages":"90-92"},"PeriodicalIF":2.2,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}