Asia-Pacific Journal of Science and Technology最新文献

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Innovation development of durian stick processing machine for transferring knowledge to foundation community 向基金会社区传递知识的榴莲棒加工机的创新开发
Asia-Pacific Journal of Science and Technology Pub Date : 2019-12-26 DOI: 10.14456/APST.2019.37
Charnchai Phontri, Ruephuwan Chantrasa
{"title":"Innovation development of durian stick processing machine for transferring knowledge to foundation community","authors":"Charnchai Phontri, Ruephuwan Chantrasa","doi":"10.14456/APST.2019.37","DOIUrl":"https://doi.org/10.14456/APST.2019.37","url":null,"abstract":"Durian is one of the most famous tropical fruits of Thailand. The consumption of durian can be in the form of both fresh durian and processed durian, such as chips, cakes, and crunches. This research aims to innovatively develop the durian stick processing machine. The machine is intended to perform efficiency and effectively according to the users’ needs before transferring the knowledge to the foundation community. The research applied Quality Function Deployment (QFD) in order to design and develop the conceptual model of the machine that responds to the true needs of the agricultural community of Khao-bai-sri, Chanthaburi Province. The research began by studying and collecting data of the fried durian stick processes. A survey of the agriculturist needs of the durian stick processing machine was then performed. The needs were analyzed by applying QFD to establish the technical specifications of the machine. The research then generated 4 alternative conceptual models and selected the most appropriate one. A prototype of the machine was constructed, tested and refined in order to verify its operations. The durian stick processing machine developed in this research was used in actual production in which the agriculturists were satisfied with the machine usage. Finally, the knowledge generated in this research was transferred to the foundation community.","PeriodicalId":8597,"journal":{"name":"Asia-Pacific Journal of Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42984789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving efficiency on warehouse management: A case study of beverage company’s distribution center 提高仓库管理效率——以饮料公司配送中心为例
Asia-Pacific Journal of Science and Technology Pub Date : 2019-09-27 DOI: 10.14456/APST.2019.29
S. Arunyanart, Piyanuch Tangkitipanusawat, K. Yoshimoto
{"title":"Improving efficiency on warehouse management: A case study of beverage company’s distribution center","authors":"S. Arunyanart, Piyanuch Tangkitipanusawat, K. Yoshimoto","doi":"10.14456/APST.2019.29","DOIUrl":"https://doi.org/10.14456/APST.2019.29","url":null,"abstract":"Inventory and warehouse management plays a key role in the performance and effectiveness of every company that carries any products. Sunk costs are inevitable when keeping a number of products to fulfill customers’ needs, while storing items with less flexibility to satisfy customers’unforeseen demands may upset business opportunities. Therefore, the utmost priorities are to manage a storage of stock inventory efficiently. The purpose of this study is to improve the efficiency on warehouse management in one of the distribution centers of a beverage company in Thailand. A number of methods have been applied to find optimal safety stock, maximize space utilization, and revise pattern of storage locations by using a Warehouse Layout Model with an ABC analysis technique to place the products that have more activities to stay effectively accessible. The results indicated a 59.46% reduction of the company’s safety stock, a 13.73% increase in storage volume which created capacity for 365 additional pallets, and a roughly 42.32% decrease for moving distance of goods in the distribution center.","PeriodicalId":8597,"journal":{"name":"Asia-Pacific Journal of Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48301012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Hybrid analytical and simulation optimization approach for production and distribution supply chain planning 生产和分销供应链规划的混合分析与仿真优化方法
Asia-Pacific Journal of Science and Technology Pub Date : 2019-09-27 DOI: 10.14456/APST.2019.25
Jirasak Ji, N. Chiadamrong
{"title":"Hybrid analytical and simulation optimization approach for production and distribution supply chain planning","authors":"Jirasak Ji, N. Chiadamrong","doi":"10.14456/APST.2019.25","DOIUrl":"https://doi.org/10.14456/APST.2019.25","url":null,"abstract":"Supply chain planning consists of designing an optimal and feasible production and distribution plan for the whole supply chain. Traditionally, two common methods of optimization are analytical and simulation-based optimization, and each of them has pros and cons. In this paper, both methods are combined to consolidate the strengths of each, also known as the hybrid analytical and simulation approach. A case study of a multi-period, multi-echelon, and multi-product production and distribution problem that maximizes the whole supply chain’s profit is introduced, to demonstrate the proposed hybrid approach. The analytical model is solved to find the optimal production-distribution plan, and then the plan is inputted into a simulation model, where uncertainties are incorporated. The proposed algorithm is then applied to identify a feasible plan that meets makespan limitation and service level requirements. Safety stock is incorporated to satisfy the service level requirements and maximize the supply chain’s profit. This procedure continues iteratively until the production-distribution plan is feasible and optimized. The results show that the proposed approach can solve for a near or possibly optimal as well as feasible solution with relatively fast computational time.","PeriodicalId":8597,"journal":{"name":"Asia-Pacific Journal of Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42822369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The effects of a yoga training program with fit ball on the physical fitness and body composition of overweight or obese women 健身球瑜伽训练对超重或肥胖女性身体素质和身体成分的影响
Asia-Pacific Journal of Science and Technology Pub Date : 2019-06-18 DOI: 10.14456/APST.2019.20
Arunya Buttichak, N. Leelayuwat, S. Bumrerraj, Y. Boonprakob
{"title":"The effects of a yoga training program with fit ball on the physical fitness and body composition of overweight or obese women","authors":"Arunya Buttichak, N. Leelayuwat, S. Bumrerraj, Y. Boonprakob","doi":"10.14456/APST.2019.20","DOIUrl":"https://doi.org/10.14456/APST.2019.20","url":null,"abstract":"A quasi-experimental study was to determine the effects of a yoga training program with fit ball on the physical fitness and body composition of overweight or obese women. Thirty participants were recruited in this study. The participants were aged between 30 to 45 years, and with 23.0 to 29.9 kg/m2 of BMI. The study was divided into three phases, namely, the pre-training period (the 1st week to the 8th week), training period (the 9th week to the 16th week), and home program period (the 17th week to the 24th week). The outcome measurements were physical fitness (flexibility, balance, muscular strength and muscular endurance) and body composition (weight, height, body mass index (BMI), waist circumference (WC), waist-hip ratio (WHR), fat percentage and muscle mass). A one-way ANOVA with repeated measures and Bonferroni were used. After training period and home program period, outcome measurements showed significant improvement except in the WHR case. It was found that the results of the yoga training program with fit ball increased after the 16th week and the 24th week. The physical fitness increased as follows: flexibility, balance, muscular strength and muscular endurance (p=0.001**). More importantly, the body composition decreased: the weight (p=0.001**); the BMI (p=0.001*); waist circumference (WC) (p=0.001*); waist-hip ratio (WHR) (p= 1.000); fat percentage (p=0.001**); and the muscular muscle mass increased (p=0.001*). Therefore, the eight-week training of yoga with fit ball can improve some parameters of physical fitness and body composition in overweight or obese women.","PeriodicalId":8597,"journal":{"name":"Asia-Pacific Journal of Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45639942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Food safety assessment of food handlers in the canteens of Khon Kaen University 孔敬大学食堂食品管理员的食品安全评估
Asia-Pacific Journal of Science and Technology Pub Date : 2019-06-18 DOI: 10.14456/APST.2019.16
Thwe Moe Phyu, A. Chaoruangrit, Patimakorn Pasuwa
{"title":"Food safety assessment of food handlers in the canteens of Khon Kaen University","authors":"Thwe Moe Phyu, A. Chaoruangrit, Patimakorn Pasuwa","doi":"10.14456/APST.2019.16","DOIUrl":"https://doi.org/10.14456/APST.2019.16","url":null,"abstract":"The objective of this study was to assess the safety knowledge (K), attitudes (A), and hygienic practices (P) of canteen food handlers who were preparing foods daily. This research was conducted at Khon Kaen University. The study was divided into four parts: 1) demographic characteristics, 2) food safety knowledge, 3) food safety attitudes and 4) hygienic practice of food handlers. Part 1 to part 3 were accomplished by food handlers throughout the suvery questionnaires. The personal hygiene and handling practices (part 4) of food handlers were observed by the researchers. Ninety food handlers participated in this research. Most of the food handlers were female (75%) whose age ranging between 36-55 (65%). Seventy-five percent of food handlers had experiences of attending the hygienic practices training. The result showed that 55.37% and 68.50% of food handlers were revealed on average levels of knowledge and personal hygiene and handling practices, respectively. Moreover, the good attitude was 77.29%. The correct scores on KAP with gender, age, education and attending hygienic training of food handlers were not significantly different (p>0.05). However, total correct scores on K with A (rs= 0.424, p=0.00) and A with P (rs = 0.207, p=0.05) were significantly different. This study concluded that it is necessary to improve the knowledge of food handlers, because they were not aware of 1) the risk of foodborne pathogens, 2) critical temperature for storing of foods, and 3) the possibility of cross contamination. Effective ongoing training programs for the food handlers must be provided to improve their knowledge and practice. The food handlers must also be encouraged to implement the good hygiene practices to reduce the outbreak of foodborne illness.","PeriodicalId":8597,"journal":{"name":"Asia-Pacific Journal of Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49046140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Pattern of shiftwork and health status among nurses in a university hospital in northeastern Thailand 泰国东北部某大学医院护士轮班模式与健康状况
Asia-Pacific Journal of Science and Technology Pub Date : 2019-06-18 DOI: 10.14456/APST.2019.19
Kampanat Wangsan, N. Chaiear, K. Sawanyawisuth, P. Klainin, K. Simajareuk
{"title":"Pattern of shiftwork and health status among nurses in a university hospital in northeastern Thailand","authors":"Kampanat Wangsan, N. Chaiear, K. Sawanyawisuth, P. Klainin, K. Simajareuk","doi":"10.14456/APST.2019.19","DOIUrl":"https://doi.org/10.14456/APST.2019.19","url":null,"abstract":"This study was aimed to explore shiftwork patterns and health status among nurses at a university hospital in northeastern Thailand. A descriptive study was conducted. The study population was 1,221. The data were collected via self-reported questionnaire including personal information and the last month shift schedule. Descriptive statistics were applied using STATA v 10. The response rate was 68.1 % (831/1,221) and completion rate was 59.1% (721/1,221). There were 82.2% (593/721) participants had performed shiftwork. The shiftwork patterns were (a) day shift plus over time, (b) day and evening shift, (c) day and night shift, and (d) rotational shift. All of rotational shift were fast rotation with irregular shift pattern (n=531; 89.5%). Even though there was no pure forward or backward rotations, the researcher divided the participants into three groups (namely, primarily forward, primarily backward, and evenly split between backward and forward). Most shift workers performed primarily backward rotational pattern (n=479; 90.2%). A minority (n=143; 24.1%) did extended shifts:  median extended shift was once a month (IQR 1-3). The majority (n=523; 88%) of participants did quick return shifts (88%) (median=11 times/month, IQR7-13) Nearly one-third (28.0%) of participants had underlying diseases such as allergic rhinitis (7.9%), asthma (1.9%), and/or dyslipidemia (1.8%). Based on a BMI > 25 kg/m2, 17.5 % of the participants were obese. Over one-tenth (12.2%) of the participants had a sleep disorder and 14.9% used sleepiness- or drowsiness-inducing medication. Most of the participants had no depression (86.4%) and were at low risk of obstructive sleep apnea (76.0%). Comparing characteristics of shift and non-shift personnel, median age, proportion of married nurses and caffeine needed were lower for shift workers than the non-shift workers. Working experiences were shorter in shift workers than the non-shift workers and there was a statistically significant difference among job position, task, work unit, and salary. Likewise, shift workers had fewer underlying diseases, using sleepiness or drowsiness drug and depression. In conclusion, there was a high proportion of shift workers represented in the study, and most nurses did rotational shift with primarily backward rotation, quick return and extended shifts which are associated with a higher health risk. The health effect from shiftwork on the current study could not be concluded however, nearly one-third revealed some kinds of underlying diseases. The association of effect from shiftwork will be presented elsewhere.","PeriodicalId":8597,"journal":{"name":"Asia-Pacific Journal of Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47596800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Characterization of exopolysaccharide (EPS) from Lactobacillus fermentum (TISTR 2514) and its potential prebiotic properties 发酵乳杆菌(TISTR 2514)胞外多糖(EPS)的鉴定及其潜在的益生元特性
Asia-Pacific Journal of Science and Technology Pub Date : 2019-01-01 DOI: 10.14456/APST.2019.1
Achara Chaiongkarn, Jirapa Dathong, Premsuda Saman, Somporn Moonmangmee, Chutima Kuancha, Lawan Chatanon, Siritorn Teetavet
{"title":"Characterization of exopolysaccharide (EPS) from Lactobacillus fermentum (TISTR 2514) and its potential prebiotic properties","authors":"Achara Chaiongkarn, Jirapa Dathong, Premsuda Saman, Somporn Moonmangmee, Chutima Kuancha, Lawan Chatanon, Siritorn Teetavet","doi":"10.14456/APST.2019.1","DOIUrl":"https://doi.org/10.14456/APST.2019.1","url":null,"abstract":"The aims of this study were to characterize and investigate the prebiotic potential of exopolysaccharides (EPS) produced by Lactobacillus fermentum TISTR2514 from Thai-fermented food. The EPS showed a symmetrical sharp peak which separated using GPC technique and its molecular weight was 48.192 kDa. HPLC analyses presented that the EPS consisted of rhamnose, galactose, mannose and glucose. The prebiotic potential of EPS produced by L. fermentum TISTR2514 was studied. The results indicated that EPS can be resisted to artificial gastric juice at pH1 for 2h and to -amylase at pH7 for 6h, in the percent of more than 89 and 82%, respectively. Furthermore, these EPS could stimulate the growth of probiotics (L.rhamnosus DSM 20021 and L. casei DSM 20011 from log 6.02 0.08 to log 8.08  0.06 CFU/ml and from log 6.030.05 CFU/ml to log 8.170.02 in 24h, respectively), which was higher than using FOS. Bacterial enzyme assessment of a combination of probiotics and EPS-producing strain L. fermentum TISTR2514 (candidate prebiotic) revealed a greater reduction in -glucuronidase activity than using probiotics or EPS alone. The ability of synbiotic (probiotics and EPS) is particularly interesting for potentially reducing the-glucuronidase activity and for decreasing the risk of colorectal cancer, however further in-depth study is required.","PeriodicalId":8597,"journal":{"name":"Asia-Pacific Journal of Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66672629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SARIMA intervention based forecast model for visitor arrivals to Chiang Mai, Thailand 基于SARIMA干预的泰国清迈游客入境预测模型
Asia-Pacific Journal of Science and Technology Pub Date : 2018-08-31 DOI: 10.14456/APST.2018.19
R. Wongsathan
{"title":"SARIMA intervention based forecast model for visitor arrivals to Chiang Mai, Thailand","authors":"R. Wongsathan","doi":"10.14456/APST.2018.19","DOIUrl":"https://doi.org/10.14456/APST.2018.19","url":null,"abstract":"The purpose of this research is to implement the forecast model for domestic and international visitor arrivals to Chiang Mai, Thailand using seasonal autoregressive integrated moving average (SARIMA) with intervention analysis. The ADF and extended HEGY tests for the unit root identify that the observed time series are regular and seasonal non-stationary. After differencing of log transformation to the series, the SARIMA model is formulated using monthly data 2000-2007 for the pre-intervention. The residuals obtained from the forecast and secondary data 2008-2013 are assessed with the prior knowledge of various significant crisis events to identify the intervention functions in the forecast model. From the analysis, the violent political turmoil is the major long-term adverse impact on the visitors, whereas the influx of Chinese visitors helps to increase the number of international visitors. The forecasting performance comparison evaluated in terms of the accuracy and reliability indicates that the proposed forecast model outperforms the other existing models for the out-of-sample forecasts. Furthermore, if the government intensifies for solving the internal politics while the provincial administrator can maintain the massive number of Chinese, Chiang Mai will welcome over 10 million visitors and will also generate tourism revenue of about USD 2,400 million in 2018 estimated from the proposed forecast model.","PeriodicalId":8597,"journal":{"name":"Asia-Pacific Journal of Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42329326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The relationship between road traffic noise and annoyance levels in Phuket Province, Thailand 泰国普吉省道路交通噪声与烦恼程度的关系
Asia-Pacific Journal of Science and Technology Pub Date : 2017-12-29 DOI: 10.14456/APST.2017.39
Kulnapa Bunnakrid, Tanasri Sihabut, W. Patthanaissaranukool
{"title":"The relationship between road traffic noise and annoyance levels in Phuket Province, Thailand","authors":"Kulnapa Bunnakrid, Tanasri Sihabut, W. Patthanaissaranukool","doi":"10.14456/APST.2017.39","DOIUrl":"https://doi.org/10.14456/APST.2017.39","url":null,"abstract":"Road traffic noise generates unpleasant sounds in communities, which not only makes enormous noise pollution in road areas, but also disrupts the quality of life in buildings located near these roads. The aim of this study was to determine the relationship between road traffic noise and annoyance levels in Phuket, Thailand. Traffic noise levels were measured during the day and night time on nine roads in Muang Phuket, Thalang, and Kathu Districts. The annoyance levels of 253 people living in these areas were determined using questionnaires. Noise annoyance level was estimated using the ICBEN method, which classified annoyance level into a five-point verbal scale (extremely, very, moderately, slightly, and not at all annoyed). The results showed that traffic noise levels (Leq 24 hr) were in the range of 70.0-70.9, 72.7-74.7, and 74.6-74.8 dB(A) in Muang Phuket, Thalang, and Kathu Districts, respectively, exceeding 70 dB(A) for the ambient noise standard of Thailand. Moreover, Ldn ranged from 74.0-75.8, 77.5-78.1, and 79.7-80.1 dB(A) in Muang Phuket, Thalang, and Kathu Districts, respectively. The average annoyance scores for traffic noise in Muang Phuket, Thalang, and Kathu were found to be 1.78, 2.52, and 2.75, respectively. Thus, the average annoyance score of Phuket Province was 2.24. The annoyance responses of residents in surveyed areas indicated that people in Muang Phuket were more sensitive to road traffic noise than those in Talang and Kathu. Moreover, the result showed a significant positive correlation between road traffic noise and annoyance level (Pearson correlation coefficient= +0.733, P=0.025).","PeriodicalId":8597,"journal":{"name":"Asia-Pacific Journal of Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41844813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Phytochemistry and Bioactive Compounds from Garcinia cowa Roxb. 牛藤的植物化学和生物活性化合物。
Asia-Pacific Journal of Science and Technology Pub Date : 2017-09-30 DOI: 10.14456/APST.2017.37.22
Ngampuk Tayana, Siripat Suteerapataranon, S. Deachathai
{"title":"Phytochemistry and Bioactive Compounds from Garcinia cowa Roxb.","authors":"Ngampuk Tayana, Siripat Suteerapataranon, S. Deachathai","doi":"10.14456/APST.2017.37.22","DOIUrl":"https://doi.org/10.14456/APST.2017.37.22","url":null,"abstract":"Phytochemical investigation of the roots of Garcinia cowa Roxb. resulted in the isolation of forty-four compounds. Of these, thirty-five were xanthones, two anthraquinones, two flavonoids and five terpenes. Their structures were spectroscopically elucidated using UV, IR, 1D NMR, and 2D NMR methods. Thirty compounds were reported for the first time as metabolites of G. cowa. One active isolated compound, β-mangostin, was found to show a strong antibacterial activity against Bacillus cereus TISTR 687 and methicillin resistant Staphylococcus aureus (MRSA)-SK1 with an MIC value of 4 mg/mL. Whereas α-mangostin showed stronger activity against B. cereus TISTR 687 and MRSA-SK1 (MIC 0.5 mg/mL) than that of vancomycin (MIC 1 mg/mL). Two compounds, cowanin and cowanol, exhibited strong antibacterial activities against B. cereus TISTR 687, MRSA‑SK1, and S. aureus TISTR 1466 with MICs in the range of 2-4 mg/mL. Isocudraniaxanthone B, xanthone V1, and kaempferol expressed good antioxidative activities with IC50 values of 19.75 ± 0.39, 19.70 ± 0.39, and 11.67 ± 0.12 μM, respectively. Additionally, an acetone extract showed cytotoxicity against Vero cells (African green monkey kidney) and anticancer activity against the standard cell culture BC-Breast cancer with IC50 values of 36.13 and 40.89 mg/mL, respectively.","PeriodicalId":8597,"journal":{"name":"Asia-Pacific Journal of Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47309847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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