{"title":"Medicinal and biological potential of Thuja occidentalis: A comprehensive review","authors":"Manish Thakur, R. Sobti, T. Kaur","doi":"10.4103/1995-7645.374353","DOIUrl":"https://doi.org/10.4103/1995-7645.374353","url":null,"abstract":"There is considerable evidence from a wide range of sources, including written texts, preserved monuments, and natural plant medicines, that demonstrate the long history of humankind's search for medicinal substances in the natural world. The purpose of this article was to compare the performance of medicinal plant Thuja (T.) occidentalis in a variety of disease-relieving conditions. The current review draws on the work of nearly two hundred original research papers indexed in Google Scholar, ScienceDirect, and the NCBI Library. The authors gatherd all the accessible data on the therapeutic effects of T. occidentalis. Although there are no published randomized controlled trials of T. occidentalis alone so far, multiple clinical investigations have validated the therapeutic efficacy of a combination herbal medication including the extract of T. occidentalis and additional immune stimulants. T. occidentalis is a plant with great potential as it is widely used in both traditional homoeopathy and modern, evidence-based phytotherapy. In vitro and in vivo models have shown its immunopharmacological potential, including its immunostimulatory, anti-cancer, anti-bacterial, anti-fungal, and antiviral activities. More researches into these plants might be done to find out if any of them have the potential to be implemented as a novel drug to treat a wide range of conditions.","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":"16 1","pages":"148 - 161"},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48524005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Ganesan, R. Sudha, G. Thangam, Sivathanu Lalitha
{"title":"Dengue positivity among blood donors in hyper-endemic region of southern India","authors":"M. Ganesan, R. Sudha, G. Thangam, Sivathanu Lalitha","doi":"10.4103/1995-7645.374358","DOIUrl":"https://doi.org/10.4103/1995-7645.374358","url":null,"abstract":"","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":"16 1","pages":"190 - 192"},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48271900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Srivastava, R. Beniwal, B. Misra, Umaer Alam, H. Deval, Rajni Kant
{"title":"Preventive strategies to innovate Japanese encephalitis control in eastern Uttar Pradesh: Accelerating towards zero incidence","authors":"N. Srivastava, R. Beniwal, B. Misra, Umaer Alam, H. Deval, Rajni Kant","doi":"10.4103/1995-7645.374352","DOIUrl":"https://doi.org/10.4103/1995-7645.374352","url":null,"abstract":"","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":"16 1","pages":"145 - 147"},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42596868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COVID-19 vaccine uptake and its determinants among teenagers and their parents in Zhejiang, China: An online cross-sectional study","authors":"Yu Huang, Qingqing Wu, Shuiyang Xu, Xiang Zhao, Lei Wang, Qiaohong Lv, Suxian Wu, Xuehai Zhang","doi":"10.4103/1995-7645.374355","DOIUrl":"https://doi.org/10.4103/1995-7645.374355","url":null,"abstract":"Objective: To examine COVID-19 vaccine uptake and its determinants among teenagers and their parents in Zhejiang, China. Methods: An online cross-sectional study was conducted among parents of teenagers in Zhejiang, China from May 1 to 31, 2022. Data were interpreted via univariate and multivariate analyses using the statistical package for the social sciences (SPSS) program. Results: A total of 11115 (96.11%) participants and 11449 (99.00%) of their children in Zhejiang, China had been vaccinated against COVID-19. Children whose parents did not receive COVID-19 vaccination were 19 times (aOR 18.96, 95%CI 12.36-29.08) more likely to be unvaccinated than their counterparts. In addition, children with no previous influenza vaccination, those whose parents doubted the COVID-19 vaccine’s safety or effectiveness, were 6.11 times (aOR 6.11, 95%CI 2.80-13.34), 8.27 times (aOR 8.27, 95%CI 5.33-12.83), and 2.69 times (aOR 2.69, 95%CI 1.11-6.50) more likely to be unvaccinated than their counterparts, respectively. COVID-19 vaccine uptake varied between different sociodemographic groups. However, the odds of receiving the COVID-19 vaccine decreased as age and education level increased. The main refusal reasons claimed by participants were that they had medical conditions that may not qualify them for vaccination (53.78%), followed by safety concerns about the vaccine (13.56%), not knowing where to get vaccinated (6.44%), and concerns about fertility issues (5.56%). Conclusions: Despite a highly encouraging level of COVID-19 vaccine uptake in Zhejiang, China, the elderly and highly educated people had lower COVID-19 vaccine uptake. It is suggested that tailored health education strategies should be taken to increase the COVID-19 vaccine uptake in such groups. Furthermore, with vaccination rates at such a high level, the pandemic is still ongoing, and public confidence in vaccines may decline. Thus, sufficient evidence-based information regarding COVID-19 vaccines should be provided to the public.","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":"16 1","pages":"176 - 186"},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41841304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Putra, Yulistiani Yulistiani, S. Soedarsono, Susi Subay
{"title":"Early efficacy of individual regimens containing bedaquiline in patients with drug resistant tuberculosis","authors":"O. Putra, Yulistiani Yulistiani, S. Soedarsono, Susi Subay","doi":"10.4103/1995-7645.372289","DOIUrl":"https://doi.org/10.4103/1995-7645.372289","url":null,"abstract":"Objective: To evaluate early efficacy of sputum conversion within 6 months of individual regimens containing bedaquiline in patients with drug resistant tuberculosis. Methods: We conducted a retrospective study among patients with drug resistant tuberculosis who were receiving individual regimens containing bedaquiline. The primary outcome was sputum conversion of both smear and culture within 6 months of treatment. We used medical records of drug resistant tuberculosis patients from January 2020 to December 2021. The study was conducted at Dr. Soetomo Hospital, Indonesia from August to October 2022. Results: In this study, 44 eligible drug resistant tuberculosis patients were initiated on regimens containing bedaquiline. There were 52.3% males and the median age was 45.5 years. The rates of previous treatment (70.5%) and lung cavity (36.4%) were high. The most common companion drugs included clofazimine, cycloserine, levofloxacin, and linezolid. Sputum smear and culture conversion was seen in 79.4% and 82.1% at the 2nd month, respectively. More than 97% patients had smear and culture conversion at the end of 6 months. Conclusions: Among drug resistant tuberculosis patients, individual regimens containing bedaquiline were associated with high rates of smear and culture conversion at the end of 6 months. Early efficacy of regimens containing bedaquiline can be used to predict cure rate at the end of treatment.","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":"16 1","pages":"169 - 175"},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49513484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A minor emphasis on the outbreak of cutaneous leishmaniasis after devastating earthquakes in Turkey","authors":"I. Ardic, N. Ardıç","doi":"10.4103/1995-7645.372288","DOIUrl":"https://doi.org/10.4103/1995-7645.372288","url":null,"abstract":"","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":"16 1","pages":"97 - 98"},"PeriodicalIF":3.1,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45603182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"COVID–19 vaccination and associated factors in Turkish healthcare workers practicing chest medicine","authors":"A. Sandal, Aylin Çifci, P. Arbak","doi":"10.4103/1995-7645.372291","DOIUrl":"https://doi.org/10.4103/1995-7645.372291","url":null,"abstract":"Objective: To evaluate the COVID-19 vaccination status and related characteristics of Turkish healthcare workers practicing chest medicine. Methods: A cross-sectional online survey was conducted among the Turkish Thoracic Society members. The survey was started on May 17, 2021, and kept open for seven weeks. The 39-item survey included the COVID-19 vaccination status and demographic, clinical, and occupational characteristics. Results: Of 378 healthcare workers participated in the survey, 354 (93.7%) reported receiving at least one dose of the COVID-19 vaccine. A total of 323 (91.2%) healthcare workers received CoronaVac vs. BioNTech/Pfizer in 31 (8.8%). In the CoronaVac group, 77 (23.8%) contracted COVID-19 when not fully vaccinated, and 13 (4.0%) when fully vaccinated; however, 16 (51.6%) healthcare workers in the BioNTech/Pfizer group got COVID-19 when not fully vaccinated, but any fully vaccinated participants did not contract COVID-19 (P=0.003). Regarding vaccine dosing, 328 (86.8%) were fully vaccinated, while 50 (13.2%) were not. Multiple regression analysis for being a non-fully vaccinated healthcare worker demonstrated a significant relationship with having any SARS-CoV-2 infection history (adjusted OR 9.57, 95% CI 3.93-23.26, P<0.001) and being a non-physician healthcare worker (adjusted OR 5.86, 95% CI 2.11-16.26, P=0.001), but a significant negative relationship with full-time working at the time of survey (adjusted OR 0.13, 95% CI 0.03-0.56, P=0.006). Conclusions: Although a majority of healthcare workers were fully vaccinated, occupational and non-occupational characteristics were related to being non-fully vaccinated. Active surveillance regarding the COVID-19 vaccination in healthcare workers is necessary to address specific parameters as barriers to vaccination.","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":"16 1","pages":"110 - 118"},"PeriodicalIF":3.1,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43747920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Mastroianni, C. Vocale, V. Sambri, T. Lazzarotto, P. Gaibani, G. Rossini, S. Varani
{"title":"Dengue and falciparum malaria co-infection in travelers returning from Burkina Faso: Report of two cases in Northeastern Italy","authors":"A. Mastroianni, C. Vocale, V. Sambri, T. Lazzarotto, P. Gaibani, G. Rossini, S. Varani","doi":"10.4103/1995-7645.372294","DOIUrl":"https://doi.org/10.4103/1995-7645.372294","url":null,"abstract":"Rationale: Malaria and dengue are the most prevalent vector-borne diseases in tropical countries. Plasmodium parasite and dengue virus (DENV) concurrent infection is possible and often under-recognized in geographical areas where these infections are both endemic. Patients concern and diagnosis: We describe the first two cases of Plasmodium falciparum and DENV-3 co-infection in travelers returning to northeastern Italy from Burkina Faso during 2013-2014. Interventions: Malaria infection in both patients was treated with mefloquine. Due to the persistence of symptoms despite of the antimalaria treatment, dengue was also investigated; the treatment of dengue was symptomatic. Outcomes: The patients were discharged in good general condition. Lessons: The need for surveillance of potential malaria and dengue co-infection in travelers returning to Europe from endemic areas is highlighted, as infection with Plasmodium does not exclude arboviral co-infection.","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":"16 1","pages":"139 - 142"},"PeriodicalIF":3.1,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48016236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge, perceptions, and practice towards adverse events following immunization surveillance among vaccination workers in Zhejiang province, China","authors":"H. Lv, Xuejiao Pan, Ying Wang, H. Liang, Hu Yu","doi":"10.4103/1995-7645.372292","DOIUrl":"https://doi.org/10.4103/1995-7645.372292","url":null,"abstract":"Objective: To access the level of knowledge, perceptions, and practice towards adverse events following immunization (AEFI) surveillance among vaccination workers in Zhejiang province, China. Methods: This was a cross-sectional survey involving 768 vaccination workers. Data were collected using self-administered questionnaires and analyzed by using SAS 9.3 software. Knowledge, perceptions, and practice on AEFI surveillance were summarized using frequency tables. The mean±SD value was used as the cut-off for defining good (values⩾mean) and poor (values<mean) knowledge, perceptions or practice. Binary logistic regression analysis was used to determine sociodemographic variables associated with knowledge, perceptions, and practice towards AEFI. Results: The proportions of good knowledge, perceptions and practice on AEFI surveillance were 78.13%, 57.81% and 66.15%, respectively. Having a higher education background, longer years of experience, previous training on AEFI and ⩾30 years of age were factors associated with good knowledge, perceptions and practice on AEFI surveillance among vaccination workers. Conclusions: Over half of the respondents had good knowledge, perceptions and practice on AEFI surveillance work. Interventions on improving the vaccination workers’ knowledge, perceptions and practice on AEFI surveillance should be considered in order to develop a more effective surveillance system.","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":"16 1","pages":"102 - 109"},"PeriodicalIF":3.1,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45449084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Why Kenya should worry about Anopheles stephensi","authors":"E. Owino","doi":"10.4103/1995-7645.372287","DOIUrl":"https://doi.org/10.4103/1995-7645.372287","url":null,"abstract":"","PeriodicalId":8559,"journal":{"name":"Asian Pacific journal of tropical medicine","volume":"16 1","pages":"99 - 101"},"PeriodicalIF":3.1,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43243585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}