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Asian Journal of Pharmaceutical Education and Research最新文献

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PHYTOCHEMICAL AND IN-VITRO ANTI-INFLAMMATORY ACTIVITY OF HYDROALCOHOLIC EXTRACT OF AEGLE MARMELOS ROOT 蜜瓜根水醇提取物的植物化学及体外抗炎活性
Asian Journal of Pharmaceutical Education and Research Pub Date : 2021-07-10 DOI: 10.38164/AJPER/10.3.2021.13-20
Jaswinder Mehta, Peenu Mahendra Joshi, S. Verma, Kashika Linnet Kumar, R. Acharya, B. Sharma
{"title":"PHYTOCHEMICAL AND IN-VITRO ANTI-INFLAMMATORY ACTIVITY OF HYDROALCOHOLIC EXTRACT OF AEGLE MARMELOS ROOT","authors":"Jaswinder Mehta, Peenu Mahendra Joshi, S. Verma, Kashika Linnet Kumar, R. Acharya, B. Sharma","doi":"10.38164/AJPER/10.3.2021.13-20","DOIUrl":"https://doi.org/10.38164/AJPER/10.3.2021.13-20","url":null,"abstract":"","PeriodicalId":8533,"journal":{"name":"Asian Journal of Pharmaceutical Education and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84924222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FORMULATION, DEVELOPMENT AND EVALUATION OF PHYTOSOMES OF SWERTIA PERENNIS 多年生獐牙菜磷脂复合物的制备、开发与评价
Asian Journal of Pharmaceutical Education and Research Pub Date : 2021-04-10 DOI: 10.38164/AJPER/10.2.2021.55-66
Akash Chouhan, S. Shah, C. Tyagi, Prabhakar Budholiya, Abdul Wazid, Firoz Shah Tuglak Khan
{"title":"FORMULATION, DEVELOPMENT AND EVALUATION OF PHYTOSOMES OF SWERTIA PERENNIS","authors":"Akash Chouhan, S. Shah, C. Tyagi, Prabhakar Budholiya, Abdul Wazid, Firoz Shah Tuglak Khan","doi":"10.38164/AJPER/10.2.2021.55-66","DOIUrl":"https://doi.org/10.38164/AJPER/10.2.2021.55-66","url":null,"abstract":"The aim of the present study was performed, Extraction of plant material using hydroalcoholic extract, Phytochemical analysis of Swertia perennis L and Formulation, development and evaluation of phytosomes. The phytochemical screening of this investigation attested the presence of several secondary metabolites with known biological antioxidant activities. Hydroalcoholic extract of aerial parts of Swertia perennis was possessing antioxidant activity due to the presence of flavonoids constituent. Flavonoids content was expressed as milligrams equivalent of Quercetin per 100 milligrams of dry extract (mg QE/100mg). Total flavonoid contents are shown in Table 7.4. From these results, Hydro-alcoholic extract showed flavonoid compounds (1.021 mg QE/100mg). Different formulation of Phytosomes were prepared using different amount of phospholipids: cholesterol and extract and were evaluated for Drug Excipient compatibility study, Entrapment efficiency and particle size analysis, In vitro drug release study of prepared Phytosomes formulation. Entrapment efficiency is an important parameter for characterizing phytosomes. When the regression coefficient values of were compared, it was observed that ‘r’ values of Higuchi was maximum i.e. 0.964 hence indicating drug release from formulations was found to follow Higuchi release kinetics.","PeriodicalId":8533,"journal":{"name":"Asian Journal of Pharmaceutical Education and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79917731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
DEVELOPMENT AND CHARACTERIZATION OF TRANSFERSOMES OF ITRACONAZOLE FOR EFFECTIVE TREATMENT OF FUNGAL DISEASE 有效治疗真菌疾病的伊曲康唑转移体的研制与表征
Asian Journal of Pharmaceutical Education and Research Pub Date : 2021-01-10 DOI: 10.38164/AJPER/10.1.2021.26-34
D. Thakre, S. Saxena, S. Jain
{"title":"DEVELOPMENT AND CHARACTERIZATION OF TRANSFERSOMES OF ITRACONAZOLE FOR EFFECTIVE TREATMENT OF FUNGAL DISEASE","authors":"D. Thakre, S. Saxena, S. Jain","doi":"10.38164/AJPER/10.1.2021.26-34","DOIUrl":"https://doi.org/10.38164/AJPER/10.1.2021.26-34","url":null,"abstract":"","PeriodicalId":8533,"journal":{"name":"Asian Journal of Pharmaceutical Education and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74493141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
STABILITY-INDICATING RP-HPLC METHOD FOR ANALYSIS OF EMTRICITABINE IN THE BULK DRUG AND IN A PHARMACEUTICAL DOSAGE FORM 稳定性指示反相高效液相色谱法分析原料药和制剂剂型中恩曲他滨的含量
Asian Journal of Pharmaceutical Education and Research Pub Date : 2021-01-10 DOI: 10.38164/AJPER/10.1.2021.78-86
V. Jain, P. Prajapati, P. Jain
{"title":"STABILITY-INDICATING RP-HPLC METHOD FOR ANALYSIS OF EMTRICITABINE IN THE BULK DRUG AND IN A PHARMACEUTICAL DOSAGE FORM","authors":"V. Jain, P. Prajapati, P. Jain","doi":"10.38164/AJPER/10.1.2021.78-86","DOIUrl":"https://doi.org/10.38164/AJPER/10.1.2021.78-86","url":null,"abstract":"","PeriodicalId":8533,"journal":{"name":"Asian Journal of Pharmaceutical Education and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80685493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME SUBSTITUTED 2-PYRAZOLINES SULPHONAMIDE HYBRID COMPOUNDS 一些取代的2-吡唑啉类磺胺杂化化合物的合成及其抑菌活性
Asian Journal of Pharmaceutical Education and Research Pub Date : 2020-10-15 DOI: 10.38164/AJPER/10.1.2021.46-63
K. Mehta, A. Jain
{"title":"SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME SUBSTITUTED 2-PYRAZOLINES SULPHONAMIDE HYBRID COMPOUNDS","authors":"K. Mehta, A. Jain","doi":"10.38164/AJPER/10.1.2021.46-63","DOIUrl":"https://doi.org/10.38164/AJPER/10.1.2021.46-63","url":null,"abstract":"","PeriodicalId":8533,"journal":{"name":"Asian Journal of Pharmaceutical Education and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84500214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
STABILITY-INDICATING RP-HPLC METHOD FOR ANALYSIS OF EMTRICITABINE IN THE BULK DRUG AND IN A PHARMACEUTICAL DOSAGE FORM 稳定性指示反相高效液相色谱法分析原料药和制剂剂型中恩曲他滨的含量
Asian Journal of Pharmaceutical Education and Research Pub Date : 2020-01-15 DOI: 10.38164/ajper/9.1.2020.10-19
Aditya Suman, B. Dubey, Bhushan Korde, B. Mishra
{"title":"STABILITY-INDICATING RP-HPLC METHOD FOR ANALYSIS OF EMTRICITABINE IN THE BULK DRUG AND IN A PHARMACEUTICAL DOSAGE FORM","authors":"Aditya Suman, B. Dubey, Bhushan Korde, B. Mishra","doi":"10.38164/ajper/9.1.2020.10-19","DOIUrl":"https://doi.org/10.38164/ajper/9.1.2020.10-19","url":null,"abstract":"","PeriodicalId":8533,"journal":{"name":"Asian Journal of Pharmaceutical Education and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72658188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IN VITRO EXPLORATION ON DEVIATION IN CERTAIN PHYSICO-CHEMICAL PROPERTIES OF DAUCUSCAROTA JUICE SUPPLEMENTED WITH PROBIOTIC LACTOBACILLUS ACIDOPHILUS 体外探讨添加嗜酸乳杆菌对萝卜汁某些理化性质的影响
Asian Journal of Pharmaceutical Education and Research Pub Date : 2019-10-15 DOI: 10.38164/ajper/8.4.2019.57-63
Mayank Tenguria, Prerna Golhani, P. Joshi, R. Bais, Arvind Chansoria
{"title":"IN VITRO EXPLORATION ON DEVIATION IN CERTAIN PHYSICO-CHEMICAL PROPERTIES OF DAUCUSCAROTA JUICE SUPPLEMENTED WITH PROBIOTIC LACTOBACILLUS ACIDOPHILUS","authors":"Mayank Tenguria, Prerna Golhani, P. Joshi, R. Bais, Arvind Chansoria","doi":"10.38164/ajper/8.4.2019.57-63","DOIUrl":"https://doi.org/10.38164/ajper/8.4.2019.57-63","url":null,"abstract":"","PeriodicalId":8533,"journal":{"name":"Asian Journal of Pharmaceutical Education and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84372978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FORMULATION DEVELOPMENT AND EVALUATION OF FAST DISSOLVING ORAL FILM OF DOLASETRON MESYLATE 甲磺酸多拉司琼速溶口服膜的研制与评价
Asian Journal of Pharmaceutical Education and Research Pub Date : 2019-10-15 DOI: 10.38164/ajper/8.4.2019.38-45
Abhishek Kumar, Richa Verma, V. Jain
{"title":"FORMULATION DEVELOPMENT AND EVALUATION OF FAST DISSOLVING ORAL FILM OF DOLASETRON MESYLATE","authors":"Abhishek Kumar, Richa Verma, V. Jain","doi":"10.38164/ajper/8.4.2019.38-45","DOIUrl":"https://doi.org/10.38164/ajper/8.4.2019.38-45","url":null,"abstract":"The aim of present work is to formulate and evaluate fast dissolving oral films of dolasetron mesylate to improve water solubility, dissolution rate, oral bioavailability and reduction of first pass metabolism and increase patient’s compliance. Oral fast dissolving films prepared by solvent casting method using water and 95% ethanol as solvents and HPMC as film forming polymer. PEG 400 was the selected plasticizers, Superdisintegrants such as croscarmellose sodium (CCS) and sodium starch glycolate (SSG) alone and also in combinations was incorporated to achieve the aim. The prepared films were evaluated for the drug content, weight variation, film thickness, disintegration time, folding endurance, percentage of moisture content and in vitro dissolution studies and taste mask studies on healthy human volunteers. Among all, the formulation F3 was found to be best formulation which releases 99.12% of the drug within 15 min and disintegration time is 47±7 sec. which was significantly high when compared to other formulation. The data obtained from In-vitro release were fitted into the various kinetic models such as Zero Order, Higuchi, First Order and Korsmeyer–Peppas model in order to determine the mechanism of drug release. When the regression coefficient values compared, it was observed that ‘r’ values of formulation F3 was maximum i.e 0.951hence indicating drug release from formulations was found to follow first order drug release kinetics.","PeriodicalId":8533,"journal":{"name":"Asian Journal of Pharmaceutical Education and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77004240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
IN VITRO ANTI- INFLAMMATORY ACTIVITY OF SEEDS OF TRIGONELLA FOENUM GRAECUM 凹凹三角铃种子体外抗炎活性研究
Asian Journal of Pharmaceutical Education and Research Pub Date : 2019-10-15 DOI: 10.38164/ajper/8.4.2019.34-37
P. K. Borude, S. A. Deshmukh, V. Trivedi
{"title":"IN VITRO ANTI- INFLAMMATORY ACTIVITY OF SEEDS OF TRIGONELLA FOENUM GRAECUM","authors":"P. K. Borude, S. A. Deshmukh, V. Trivedi","doi":"10.38164/ajper/8.4.2019.34-37","DOIUrl":"https://doi.org/10.38164/ajper/8.4.2019.34-37","url":null,"abstract":"","PeriodicalId":8533,"journal":{"name":"Asian Journal of Pharmaceutical Education and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81971537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
STUDY OF PHYTOCONSTITUENTS AND EVALUATION OF ANTIPYRETIC ACTIVITY OF HYDROALCOHOLIC LEAVES EXTRACT OF CARICA PAPAYA LINN AND TINOSPORA CORDIFOLIA ON BREWER’S YEAST INDUCED PYREXIA IN WISTAR RATS 番木瓜叶水醇提取物和青霉叶水醇提取物对啤酒酵母致大鼠发热的植物成分研究及解热作用评价
Asian Journal of Pharmaceutical Education and Research Pub Date : 2019-10-15 DOI: 10.38164/ajper/8.4.2019.11-20
R. Saket, R. Goswami, S. Jain, P. Rathore
{"title":"STUDY OF PHYTOCONSTITUENTS AND EVALUATION OF ANTIPYRETIC ACTIVITY OF HYDROALCOHOLIC LEAVES EXTRACT OF CARICA PAPAYA LINN AND TINOSPORA CORDIFOLIA ON BREWER’S YEAST INDUCED PYREXIA IN WISTAR RATS","authors":"R. Saket, R. Goswami, S. Jain, P. Rathore","doi":"10.38164/ajper/8.4.2019.11-20","DOIUrl":"https://doi.org/10.38164/ajper/8.4.2019.11-20","url":null,"abstract":"","PeriodicalId":8533,"journal":{"name":"Asian Journal of Pharmaceutical Education and Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74972635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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