Asian Journal of Pharmaceutical Research and Development最新文献_第10页

Development and Validation Method for Simultaneous Investigation of Ambroxol Hydrochloride and N-Acetyl Cysteine In Bulk And Pharmaceutical Formulation By RP-HPLC. 反相高效液相色谱法同时测定盐酸氨溴索和n -乙酰半胱氨酸原料药和制剂中含量的方法建立与验证。

Asian Journal of Pharmaceutical Research and Development Pub Date : 2022-12-14 DOI: 10.22270/ajprd.v10i6.1188

Lokesh T. Thote, D. Dhabarde, J. Baheti, S. Borkar, Swati Bhusari

引用次数: 0

Qualitative and Quantitative Screening of Phytochemicals in Polar and Non Polar Solvent Extracts of Stem Bark and Leaves of Saraca Indica 菝葜茎、皮、叶极性和非极性溶剂提取物中植物化学物质的定性和定量筛选

Asian Journal of Pharmaceutical Research and Development Pub Date : 2022-12-14 DOI: 10.22270/ajprd.v10i6.1185

S. Gogate, Rahul Mathur, Arpit Raghuvanshi, A. Yadav, Deepa Dhurve, Dheeraj Kumar Sen, D. Raj, J. Rathi

引用次数: 1

Estimation of Caffeine in Different Marketed Samples of Tea 不同市售茶叶样品中咖啡因含量的测定

Asian Journal of Pharmaceutical Research and Development Pub Date : 2022-12-14 DOI: 10.22270/ajprd.v10i6.1186

S. Gogate, R. Mathur, Adarsh Mathur, Adarsh Hukre, Abdur Rehman, Afzal Hussain, J. Rathi

引用次数: 0

Prevalence and Evaluation of Complications in Valvular Heart Disease Patients In Tertiary Care Hospital 三级医院瓣膜性心脏病患者并发症发生率及评价

Asian Journal of Pharmaceutical Research and Development Pub Date : 2022-12-14 DOI: 10.22270/ajprd.v10i6.1187

Amtul Rafeh Mariya, Arshiya Mubeen Batool, Sri Praneeth Polamuri, Anupama Koneru, S. P. Srinivas Nayak

{"title":"Prevalence and Evaluation of Complications in Valvular Heart Disease Patients In Tertiary Care Hospital","authors":"Amtul Rafeh Mariya, Arshiya Mubeen Batool, Sri Praneeth Polamuri, Anupama Koneru, S. P. Srinivas Nayak","doi":"10.22270/ajprd.v10i6.1187","DOIUrl":"https://doi.org/10.22270/ajprd.v10i6.1187","url":null,"abstract":"Background: One of the major outcomes of valvular heart disease have been chronic complications that in turn have led to the reduced quality of life of patients. These complications have indeed caused immense burden on the health care system and has led to increased mortality rate. Objective: To determine prevalence rate and to evaluate complications of valvular heart disease patients. Methods: This is a cross sectional-based study carried out in a single hospital in Hyderabad, India. The survey was carried out over a year in India. The source of data collection was through case sheets and lab reports. Results: Of the total 102 subjects, valvular diseases were more prevalent in the age group of 51-60 and females were found to be more affected than males. Complications were less or equal to no after the procedure of valve replacement was performed in patients with severe cases though some patients showed complications even after surgery, but were stable after a long time of monitoring. 1% of valve prolapse cases were seen and 3% deaths due to the disease. St.jude mechanical valve of different sizes, 19 EPR biological valve and aortic valve implants were majorly used for valve replacement procedure. Conclusion: The study concludes that valvular diseases are more prevalent in the age group 51-60, and females were more affected by valvular diseases than males. Hypertension and diabetes mellitus were found to be the major comorbidities in valvular heart disease patients. \u0000 ","PeriodicalId":8526,"journal":{"name":"Asian Journal of Pharmaceutical Research and Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80697576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Necessity, Importance, Future Aspects and Challenges of Pharmacovigilance 药物警戒的必要性、重要性、未来展望和挑战

Asian Journal of Pharmaceutical Research and Development Pub Date : 2022-12-14 DOI: 10.22270/ajprd.v10i6.1202

Shaik Sameena, S. Shafi, Dhumal P.B

{"title":"Necessity, Importance, Future Aspects and Challenges of Pharmacovigilance","authors":"Shaik Sameena, S. Shafi, Dhumal P.B","doi":"10.22270/ajprd.v10i6.1202","DOIUrl":"https://doi.org/10.22270/ajprd.v10i6.1202","url":null,"abstract":"Pharmacovigilance (PV) is kind of a sunshade to clarify the processes for observance and evaluating Adverse Drug Reactions (ADRs) and it’s a key part of effective drug regulation systems, clinical follow and public health programs. Spontaneous news of ADRs could be an important part of PV & it becomes a major disadvantage in developing countries. Knowledge of PV might sort the thought for interventions aimed toward up news rates and decreasing ADRs. PV could be an important and integral part of clinical analysis & it jointly plays employment among the help system through observance and interaction of medication and there effects among the body. Nowadays in state, PV provides awareness relating to ADRs and this review provides knowledge relating to implementation for determination of current problems. India’s rising stage; there is heaps to be done and told, the sphere of PV, in ensuring that the safe implementation of the activities and work done is achieved. Their increasing kind of hospitalization of patients as a results of ADRs and it becomes a challenge to hunt out the precise cause, once a patient is treated with multiple medication at a similar time. PV helps in safe and convenient use of pharmaceutical medication. The foremost objective of PV is that the assessment of benefit-risk profile of drug for higher potency and safety in patients. This review explains the need of Pharmacovigilance in companies, its growth in various centuries and current standing among the country. \u0000 ","PeriodicalId":8526,"journal":{"name":"Asian Journal of Pharmaceutical Research and Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78241784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Determinants of Active Aging for Improving Elderly Abilities 积极老龄化对提高老年能力的决定因素

Asian Journal of Pharmaceutical Research and Development Pub Date : 2022-12-14 DOI: 10.22270/ajprd.v10i6.1203

Bondan Palestin, S. Kholifah, ,. Y. D. Arna

{"title":"The Determinants of Active Aging for Improving Elderly Abilities","authors":"Bondan Palestin, S. Kholifah, ,. Y. D. Arna","doi":"10.22270/ajprd.v10i6.1203","DOIUrl":"https://doi.org/10.22270/ajprd.v10i6.1203","url":null,"abstract":"An elderly group is a vulnerable group due to the aging process. The declining health conditions of the elderly have an impact on the increasing dependence of the elderly on family and society. The state of the elderly is healthy holistically and actively affects the productive elderly. Increasing productivity among the elderly is significant in reducing dependence on others. One of the efforts to increase productivity among the elderly is the empowerment process. This research consists of two stages, (1) analytical observational method and (2) Focus Group Discussion. researchers will follow up on the research by Productive Elderly Indicator Measuring Tool based on an android application. The results of the study showed that there was a significant effect of holistic health conditions on increasing ability with a coefficient value of 0.268 with a significance of 0.003 (p-value <0.05). A positive coefficient means that the more holistic health conditions, the greater the ability of the elderly. There is a significant effect of the active determinant on increasing ability with a coefficient value of 0.449 with a significance of 0.000 (p-value <0.05). The positive coefficient means that the more active determinants are, the greater the ability of the elderly. There is a significant effect of increasing the ability of productive elderly with a coefficient value of 0.720 with a significance of 0.000 (p-value <0.05). The positive coefficient means that the increasing ability of the elderly will increase productivity elderly. \u0000 ","PeriodicalId":8526,"journal":{"name":"Asian Journal of Pharmaceutical Research and Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87255957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacological Vunerability of Chemophoric Groups 趋化基团的药理学易感性

Asian Journal of Pharmaceutical Research and Development Pub Date : 2022-12-14 DOI: 10.22270/ajprd.v10i6.1194

Luv Kush

引用次数: 0

A Review on Microspheres: Preparation, Characterization and Applications 微球的制备、表征及应用研究进展

Asian Journal of Pharmaceutical Research and Development Pub Date : 2022-12-14 DOI: 10.22270/ajprd.v10i6.1204

Prasad Galande, V. Yadav, S. Borkar

引用次数: 1

Nanoemulsion as Novel Drug Delivery System: Development, Characterization and Application 纳米乳作为新型给药系统:开发、表征及应用

Asian Journal of Pharmaceutical Research and Development Pub Date : 2022-12-14 DOI: 10.22270/ajprd.v10i6.1205

Nikhil Dhumal, V. Yadav, S. Borkar

{"title":"Nanoemulsion as Novel Drug Delivery System: Development, Characterization and Application","authors":"Nikhil Dhumal, V. Yadav, S. Borkar","doi":"10.22270/ajprd.v10i6.1205","DOIUrl":"https://doi.org/10.22270/ajprd.v10i6.1205","url":null,"abstract":"A dispersed nano-system with droplet sizes as small as submicrons is called a nanoemulsion. Nanoemulsions are thermodynamically stable, transparent, isotropic liquid mixtures of oil, water, surfactant, and co-surfactant. Nanoemulsion typically has droplet sizes between 20 and 200 nanometer. The size and composition of the scattered particles in a continuous phase are the primary distinctions between an emulsion and a nanoemulsion. This approach is intended to alleviate some of the issues that low bioavailability and noncompliance, two issues with traditional drug delivery systems, bring up.Today, nano emulsion can be created for a number of administration routes. A nano emulsion formulation can be considered an effective, secure, and patient-compliant pharmaceutical delivery method. Nowadays, nano emulsions have attracted a lot of interest in pharmacotherapy, dosage form design, and research. A surfactant and a cosurfactant can preserves the stability components of nanoemulsion. Brief details on the types, preparation process, stability, assessment, and applications of nanoemulsion are provided in this review. \u0000 ","PeriodicalId":8526,"journal":{"name":"Asian Journal of Pharmaceutical Research and Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74396788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Role of Ginsenosides in Myocardial Ischemic Injury-A Systematic Review 人参皂苷在心肌缺血损伤中的作用系统综述

Asian Journal of Pharmaceutical Research and Development Pub Date : 2022-12-14 DOI: 10.22270/ajprd.v10i6.1191

Song Wenhao, Wang Quanwei, Fu Wenwen, Zhang Ce, Wang Tian

{"title":"The Role of Ginsenosides in Myocardial Ischemic Injury-A Systematic Review","authors":"Song Wenhao, Wang Quanwei, Fu Wenwen, Zhang Ce, Wang Tian","doi":"10.22270/ajprd.v10i6.1191","DOIUrl":"https://doi.org/10.22270/ajprd.v10i6.1191","url":null,"abstract":"Topical herbal formulations are gaining more attention in wound healing due to their safety and efficacy. This is a systematic review of the effects of Curcuma longatopical formulations on wound healing. C. longa is a traditional medicinal plant used due to its antimicrobial, antioxidant, anti-inflammatory, and wound healing properties. Studies carried outas randomized control trials and clinical trials were included for the analysis of this review. Searches were conducted in PubMed, Scopus, Cochrane Central Register of Controlled Trials, and Google scholar (up to March 2022) with 04 studies meeting the inclusion criteria. All randomized control trials and clinical trials have shown a significant improvement in wound healing. The topical formulations containing C. longa as an ingredient have reportedly improved wound healing in cases of eczema, radiodermatitis, acne vulgaris, atopic dermatitis, ichthyosis vulgaris, senile pruritis, and xerotic skin conditions, according to the studies covered in this review.This review identified some evidence that C. longa extract has good effects for wound healing, in accordance with its use in traditional medicine. To evaluate the impact of C. longa on wound healing, including complications, larger, well-designed randomized control trials are required. \u0000 ","PeriodicalId":8526,"journal":{"name":"Asian Journal of Pharmaceutical Research and Development","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82294741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0