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Expression of CD30 in testis and Epididymis of adult mice CD30在成年小鼠睾丸和附睾中的表达
Korean journal of biological sciences Pub Date : 2004-01-01 DOI: 10.1080/12265071.2004.9647751
Y. Choo, S. Nam
{"title":"Expression of CD30 in testis and Epididymis of adult mice","authors":"Y. Choo, S. Nam","doi":"10.1080/12265071.2004.9647751","DOIUrl":"https://doi.org/10.1080/12265071.2004.9647751","url":null,"abstract":"CD30 is a member of tumor necrosis factor receptor (TNFR) superfamily and has pleiotropic functions including cell activation, proliferation, differentiation, and death, depending on cell types and stage of differentiation. Although CD30 expression has been described mainly in hematopoietic tissues, several types of nonhematopoietic tumors including embryonic carcinoma and germ‐cell tumors express CD30. We examined CD30 distribution in the testis and epididymis from wild type and CD30‐deficient mice. In the testis, spermatogonia, spermatocytes and Sertoli cells expressed CD30, but not in spermatids. Spermatogonia and spermatocytes near the basement membrane strongly reacted to anti‐CD30. In the epididymis, CD30 expression was exclusively observed in luminal epithelia and some interstitial cells. Taken together, these results show a spatio‐temporal regulation of CD30 expression in mouse testis and epididymis and suggest a possible role of CD30 in spermatogonia and spermatocytes.","PeriodicalId":85060,"journal":{"name":"Korean journal of biological sciences","volume":"8 1","pages":"197 - 203"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/12265071.2004.9647751","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59656495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Administration of agonistic anti‐4–1 BB monoclonal antibody inhibits melanoma metastasis via IFN‐γ production 拮抗- 4-1 BB单克隆抗体通过IFN - γ的产生抑制黑色素瘤转移
Korean journal of biological sciences Pub Date : 2004-01-01 DOI: 10.1080/12265071.2004.9647743
S. Ju, Sang-C. Lee, M. Seok, Byung-Sam Kim
{"title":"Administration of agonistic anti‐4–1 BB monoclonal antibody inhibits melanoma metastasis via IFN‐γ production","authors":"S. Ju, Sang-C. Lee, M. Seok, Byung-Sam Kim","doi":"10.1080/12265071.2004.9647743","DOIUrl":"https://doi.org/10.1080/12265071.2004.9647743","url":null,"abstract":"The purpose of this study was to analyze inhibitory effects of anti‐4–1 BBmonoclonal antibody on melanoma metastasis. The 4–1 BB (CD137) T cell molecule is amember of the TNF receptor family and its activation by either 4–1 BB ligand or antibody induces T cell activation and growth. In the present study, administration of anti‐4–1BB mAb induced inhibition of melanoma metastasis. Agonistic anti‐4–1 BB mAb induced not only CD8+4–1BB+ T cells but also CD8+IFN‐γ+ T cell population. In the presence of anti‐CD3 antibody, lymphocytes produced high levels of IFN‐γ and low levels of IL‐4 in anti‐4–1 BB mAb treated group. Exposure of melanoma cells to IFN‐γ induced expression of MHC‐I molecules. Thus, the increase in number of CD8+ T cells and enhanced MHC‐I expression on B16F10 cells by augmented IFN‐γ production in response to anti‐4–1 BB mAb may result in suppression of tumor growth and metastasis.","PeriodicalId":85060,"journal":{"name":"Korean journal of biological sciences","volume":"8 1","pages":"117 - 123"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/12265071.2004.9647743","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59656533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two new marine psammocinian sponges (Demospongiae: Dictyoceratida: Irciniidae) from Korea 文章题目韩国海生沙棘海绵二新种(Demospongiae: dictyoceratia: ircinciidae)
Korean journal of biological sciences Pub Date : 2004-01-01 DOI: 10.1080/12265071.2004.9647746
K. Lee, C. Sim
{"title":"Two new marine psammocinian sponges (Demospongiae: Dictyoceratida: Irciniidae) from Korea","authors":"K. Lee, C. Sim","doi":"10.1080/12265071.2004.9647746","DOIUrl":"https://doi.org/10.1080/12265071.2004.9647746","url":null,"abstract":"Two new species of the genus Psammocinia (Dictyoceratida, Irciniidae), P. conulosa n. sp. and P. ulleungensis n. sp., are described from Namhaedo Island and Ulleungdo Island, Korea. Psammocinia conulosa n. sp. seems to be close to both P. amodes Cook and Bergquist, 1998 and P. hawere Cook and Bergquist, 1996 on the basis of the skeletal structure. However, these three species are clearly separated by the following differences: Shape of P. amodes is spatulate and thin, with a broad blade narrowing to a semi‐cylindrical stalk; P. hawere forms cups with a shallow excavated bowl, and attached to the substratum by a narrow base. The whole surface of the new species is very finely conulose. Psammocinia ulleungensis n. sp. is similar to P. gageoensis Sim and Lee, 2001 in shape, but this species is easily distinguished from P. gageoensis by the simple skeletal structure.","PeriodicalId":85060,"journal":{"name":"Korean journal of biological sciences","volume":"8 1","pages":"139 - 143"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/12265071.2004.9647746","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59656137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Molecular DNA systematic analyses of East Asian mammals: Sequence Variation of cytochrome b Gene and Control Region of Mitochondrial DNA of Common Otter, Lutra lutra lutra L. (Mammalia, Carnivora) from Korea 东亚哺乳动物分子DNA系统分析:韩国普通水獭(哺乳动物，食肉目)细胞色素b基因序列变异及线粒体DNA控制区
Korean journal of biological sciences Pub Date : 2004-01-01 DOI: 10.1080/12265071.2004.9647755
H. Koh, Minyoung Yoo, Bae Geun Lee, Jeong Gyu Park
{"title":"Molecular DNA systematic analyses of East Asian mammals: Sequence Variation of cytochrome b Gene and Control Region of Mitochondrial DNA of Common Otter, Lutra lutra lutra L. (Mammalia, Carnivora) from Korea","authors":"H. Koh, Minyoung Yoo, Bae Geun Lee, Jeong Gyu Park","doi":"10.1080/12265071.2004.9647755","DOIUrl":"https://doi.org/10.1080/12265071.2004.9647755","url":null,"abstract":"Sequences of cytochrome b gene and control region of mitochondrial DNA from Korean common otters (Lutra lutra lutra L.) were examined to provide the genetic information for the conservation of this subspecies. Two haplotypes and one haplotype were revealed in cytochrome b gene and control region, respectively. The available sequences of European common otter (L. l. lutra) from GenBank were compared together with those of Korean common otter in order to determine the degree of sequence variation between them. In cytochrome b gene sequences, two haplotypes from Korea and two haplotypes of Europe showed differences in 12 of 1,045 sites. The Tamura‐Nei nucleotide distances between two European haplotypes was 0.10% and those between two Korean haplotypes was also 0.10%, but those between Korean haplotypes and European ones ranged from 0.96% to 1.16%. In the control region, one Korean haplotype and seven European ones showed differences in seven of 300 sites; the Tamura‐Nei distances among seven European haplotypes were 0.34% to 1.01%, but those between Korean haplotype and European ones ranged from 1.01% to 1.69%. Although further molecular and morphological studies with specimens from eastern Asia including Amur region and northeast China are needed, it is possible that the Korean common otter might be closer or identical to the far‐eastern Asian common otter, L. I. amurensis Dybowski.","PeriodicalId":85060,"journal":{"name":"Korean journal of biological sciences","volume":"8 1","pages":"231 - 233"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/12265071.2004.9647755","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59656178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Two new species of siphonostomatoid copepods (crustacea) associated with the stoloniferan coral tubipora musica (Linnaeus) from Madagascar 与马达加斯加匍匐茎珊瑚(Linnaeus)有亲缘关系的两新种(甲壳纲)
Korean journal of biological sciences Pub Date : 2004-01-01 DOI: 10.1080/12265071.2004.9647750
Il-Hoi Kim
{"title":"Two new species of siphonostomatoid copepods (crustacea) associated with the stoloniferan coral tubipora musica (Linnaeus) from Madagascar","authors":"Il-Hoi Kim","doi":"10.1080/12265071.2004.9647750","DOIUrl":"https://doi.org/10.1080/12265071.2004.9647750","url":null,"abstract":"Two new species of siphonostomatoid copepods, Asterocheres tubiporae n. sp. and Entomopsyllus stocki n. sp., associated with the stoloniferan coral Tubipora musica (Linnaeus) are described from Madagascar. Asterocheres tubiporae is characterized by the possession of a large posteroventral process on the caudal ramus and the elongated free segment of leg 5. Entomopsyllus stocki is readily distinguished from its congeners by the possession in the female of 15‐segmented antennule and three spines plus two setae on the third exopodal segment of leg 4.","PeriodicalId":85060,"journal":{"name":"Korean journal of biological sciences","volume":"8 1","pages":"187 - 196"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/12265071.2004.9647750","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59656483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Structural characterization of mouse HAUSP, a proteolysis regulator of p53 p53蛋白水解调节因子小鼠HAUSP的结构表征
Korean journal of biological sciences Pub Date : 2004-01-01 DOI: 10.1080/12265071.2004.9647752
Hye-Jin Lee, Kyong-Jai Yoo, K. Baek
{"title":"Structural characterization of mouse HAUSP, a proteolysis regulator of p53","authors":"Hye-Jin Lee, Kyong-Jai Yoo, K. Baek","doi":"10.1080/12265071.2004.9647752","DOIUrl":"https://doi.org/10.1080/12265071.2004.9647752","url":null,"abstract":"The tumor suppressor protein p53 is stabilized by the herpes‐virus‐associated ubiquitin‐specific protease (HAUSP), a deubiquitinating enzyme. We previously isolated and characterized a mouse orthologue of HAUSP, mHAUSP. mHAUSP cDNA consisted of 3,312 bp encodes 1,103 amino acids with a molecular weight of approximately 135 kDa containing highly conserved Cys, Asp (I), His, and Asn/Asp (II) domains. In this study, we carried out site‐directed mutagenesis of 6 conserved amino acids (Cys224, Gln231, Asp296, His457, His465, and Asp482) in Cys box, QQD box, and His box. Interestingly, the conserved Gln 231 was not essential for the catalytic activity of mHAUSP. However, the other conserved amino acids were required for deubiquitinating activity of mHAUSP. We performed isopeptidase assay and confirmed that mHAUSP is able to remove ubiquitin from ubiquitinated substrates. In addition, we observed that mHAUSP induces apoptosis in HeLa cells.","PeriodicalId":85060,"journal":{"name":"Korean journal of biological sciences","volume":"8 1","pages":"205 - 212"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/12265071.2004.9647752","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59656557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new sponge of the genus Phorbas (Poecilosclerida: Hymedesmiidae) from Gageodo island (So‐Huksando), Korea 标题韩国加古多岛(So‐Huksando) Phorbas属海绵一新记录(水蛭目:水蛭科)
Korean journal of biological sciences Pub Date : 2004-01-01 DOI: 10.1080/12265071.2004.9647745
C. Sim, H. Kim
{"title":"A new sponge of the genus Phorbas (Poecilosclerida: Hymedesmiidae) from Gageodo island (So‐Huksando), Korea","authors":"C. Sim, H. Kim","doi":"10.1080/12265071.2004.9647745","DOIUrl":"https://doi.org/10.1080/12265071.2004.9647745","url":null,"abstract":"A taxonomic study on marine sponges was conducted with materials collected from Gageodo Island, Korea, from August 1999 to July 2001 by SCUBA diving. Among them, Phorbas gukhulensis n. sp. is new to science. Phorbas gukhulensis n. sp. is similar to P. fitictius Pulitzer‐Finali from which it differs in spicule size and growth form.","PeriodicalId":85060,"journal":{"name":"Korean journal of biological sciences","volume":"8 1","pages":"135 - 137"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/12265071.2004.9647745","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59656096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A new sponge of the genus haliclona (gellius) (haplosclerida: Chalinidae) from gageodo island (so‐huksando), Korea 文章标题韩国加古多岛(so‐huksando)海螺属海绵一新记述(单孔虫目:海螺科)
Korean journal of biological sciences Pub Date : 2004-01-01 DOI: 10.1080/12265071.2004.9647757
H. Kim, C. Sim
{"title":"A new sponge of the genus haliclona (gellius) (haplosclerida: Chalinidae) from gageodo island (so‐huksando), Korea","authors":"H. Kim, C. Sim","doi":"10.1080/12265071.2004.9647757","DOIUrl":"https://doi.org/10.1080/12265071.2004.9647757","url":null,"abstract":"A taxonomic study on marine sponges was conducted by SCUBA diving at Gageodo Island, Korea from August 1999 to July 2001. Among them, Haliclona (Gellius) coreana n. sp. turned out to be new to science. This new species seems to be close to H. (G.) arcoferus Vosmaer, 1885, based on the type of spicules. However, it is different in size of toxa and growth form. Toxa of the new species is half in length compared to H. (G.) arcoferus. The growth form is jar shaped in this new species, but flat in H. (G.) arcoferus.","PeriodicalId":85060,"journal":{"name":"Korean journal of biological sciences","volume":"8 1","pages":"247 - 250"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/12265071.2004.9647757","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59656256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Comparative analysis of the responses to intruders with anxiety‐related behaviors of mouse 小鼠焦虑相关行为对入侵者反应的比较分析
Korean journal of biological sciences Pub Date : 2004-01-01 DOI: 10.1080/12265071.2004.9647764
Sanghyeon Kim, Eunchai Kang, Chankyu Park
{"title":"Comparative analysis of the responses to intruders with anxiety‐related behaviors of mouse","authors":"Sanghyeon Kim, Eunchai Kang, Chankyu Park","doi":"10.1080/12265071.2004.9647764","DOIUrl":"https://doi.org/10.1080/12265071.2004.9647764","url":null,"abstract":"Anxiety in mice can be measured by behavioral reactivity to social or non‐social Stressors. These behaviors were compared by performing the resident‐intruder test (social) as well as the light‐dark transition and open‐field tests (non‐social) for the FVB, C57BL/6, and BALB/c lines of mouse. The three inbred lines showed significant differences in their responses to intruder mice. Three factors, accounting for about 68% of the total variance, were extracted from the scores obtained from the three behavioral tests. The first two major factors are primarily associated with the anxiety‐related behaviors. One includes anxiety behaviors with a locomotive basis, while the other includes defecation measured in both anxiety tests. The third factor explains the three social behaviors, facial investigation, ano‐genital investigation, and following, observed in the resident intruder test, although facial investigation is also moderately associated with the second factor. The results indicate that the behavioral responses to an intruder share a component distinct from anxiety‐related behaviors.","PeriodicalId":85060,"journal":{"name":"Korean journal of biological sciences","volume":"8 1","pages":"301 - 306"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/12265071.2004.9647764","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59656572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
First larvae of Lebbeus comanthi and Thor amboinensis (Decapoda: Hippolytidae) hatched in the laboratory 在实验室里孵化出了第一批黄斑白蛉和黄斑白蛉(十足目:河马科)的幼虫
Korean journal of biological sciences Pub Date : 2004-01-01 DOI: 10.1080/12265071.2004.9647729
Hoi-Jeong Yang, J. Okuno
{"title":"First larvae of Lebbeus comanthi and Thor amboinensis (Decapoda: Hippolytidae) hatched in the laboratory","authors":"Hoi-Jeong Yang, J. Okuno","doi":"10.1080/12265071.2004.9647729","DOIUrl":"https://doi.org/10.1080/12265071.2004.9647729","url":null,"abstract":"The decapodid stage of Lebbeus comanthi Hayashi and Okuno and the first zoea of Thor amboinensis (De Man) are described based on laboratory‐hatched eggs from females collected from Japan. The decapodid stage of L. comanthi is readily distinguished from that of L. groenlandicus by the carapace without anteroventral denticle and tooth behind rostrum, the absence of the antennal spine, the four‐segmented outer flagellum of the antennule, the absence of the palp of the mandible, and the telson with posterior margin concaved medially and without dorsolateral spine. The carapace with anteroventral denticle and the third abdominal somite distinctly curved in lateral view distinguish the first zoea of T. amboinensis from that of T. dobkini Chace and T. floridanus Kingsley. Larval characters of the genus Thor are summarized.","PeriodicalId":85060,"journal":{"name":"Korean journal of biological sciences","volume":"8 1","pages":"19 - 25"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/12265071.2004.9647729","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"59656064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
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