Asian Journal of Chemical Sciences最新文献_第2页

Ecological and Human Health Risks Assessment of Arsenic in Sediments Around Gold Mining Areas in Northern Côte d’Ivoire 科特迪瓦北部金矿开采区周围沉积物中砷的生态和人类健康风险评估

Asian Journal of Chemical Sciences Pub Date : 2023-12-19 DOI: 10.9734/ajocs/2023/v13i6277

Koffi Pierre dit Adama N’goran, Tano Patrice Fato, N’guessan Louis Berenger Kouassi, D. Diabaté

{"title":"Ecological and Human Health Risks Assessment of Arsenic in Sediments Around Gold Mining Areas in Northern Côte d’Ivoire","authors":"Koffi Pierre dit Adama N’goran, Tano Patrice Fato, N’guessan Louis Berenger Kouassi, D. Diabaté","doi":"10.9734/ajocs/2023/v13i6277","DOIUrl":"https://doi.org/10.9734/ajocs/2023/v13i6277","url":null,"abstract":"Arsenic contamination of sediments is a worldwide concern, both for the environment and for human health. However, few data are available on the state of arsenic pollution in sediments near artisanal and industrial gold mining areas in Côte d'Ivoire. The aim of this study is to assess the spatial distribution of arsenic and its ecological and human health risks in sediments around gold mining areas in northern Côte d'Ivoire. Sampling was carried out in artisanal and industrial mining areas in Korhogo and Tengrela, northern Côte d'Ivoire. Spatial differences were determined using analysis of variance. Pollution indices were studied using the contamination factor and the enrichment factor. Non-carcinogenic and carcinogenic risk indices were used to investigate human health risks. The study revealed total arsenic concentrations ranging from 1.64 ± 0.04 to 159.72 ± 51.91 µg/g. It found Arsenic concentrations in sediments varied considerably from station to station. The results of the contamination factor indicated that the sediments were weakly to very strongly contaminate with arsenic. Non-carcinogenic risk index values ranged from 1.83E-04 to 1.78E-02, indicating low adverse effects on the surrounding habitats. In addition, the results of the potential risk (CRt) for human health revealed the existence of significant carcinogenic risks from arsenic for residents in the vicinity of the Tongon mining area.","PeriodicalId":8505,"journal":{"name":"Asian Journal of Chemical Sciences","volume":" 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138962609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Method Development and Validation for the Simultaneous Estimation of Pregabalin, Methylcobalamin and Nortriptyline in Sustained Release Tablet Dosage Form Using UV-Spectrophotometry 使用紫外分光光度法同时测定缓释片剂型中普瑞巴林、甲钴胺和去甲替林的方法开发与验证

Asian Journal of Chemical Sciences Pub Date : 2023-12-16 DOI: 10.9734/ajocs/2023/v13i6276

Sonali Sonulkar, Khush R. Jain, Fariah F. Rizwani, Rakesh Somani, Rupesh Pingale

{"title":"Method Development and Validation for the Simultaneous Estimation of Pregabalin, Methylcobalamin and Nortriptyline in Sustained Release Tablet Dosage Form Using UV-Spectrophotometry","authors":"Sonali Sonulkar, Khush R. Jain, Fariah F. Rizwani, Rakesh Somani, Rupesh Pingale","doi":"10.9734/ajocs/2023/v13i6276","DOIUrl":"https://doi.org/10.9734/ajocs/2023/v13i6276","url":null,"abstract":"To method develop and validate simple, linear, rapid, cost effective, precise, accurate and economical for the simultaneous estimation of Pregabalin, Methylcobalamin and Nortriptyline in sustained release tablet dosage form using UV-Spectrophotometry. The drug obeyed the Beer’s law and showed good correlation of concentration with absorption which reflect in linearity. The UV- Spectroscopic method was developed for estimation of Pregabalin, Methylcobalamin and Nortriptyline in sustained release tablet dosage form and also validated as per ICH guidelines. The method is based on measurement of absorbance at three wavelengths 219 nm, 222 nm, and 239 nm in Ethanol and distilled water. Linearity graph of Pregabalin, Methylcobalamin and Nortriptyline were found to be linear in the concentration ranges of 30-150 µg/ml, 0.6-3.0 µg/ml and 2-10 µg/ml. The correlation coefficient (R2) values at three wavelengths 219 nm, 222 nm, and 239 nm for Pregabalin are 0.9996, 0.9929, and 0.9996; for Methylcobalamin (R2) values are 0.9998, 0.9991, and 0.9997; for Nortriptyline (R2) values are 1.0, 0.9992 and 0.9997. The low % RSD values indicate method to be accurate and precise. The % recoveries of Pregabalin, Methylcobalamin and Nortriptyline were in the range of (99.30%-1-1.61%), (98.89%-100.02%) and (99.69%-100.23%) which was within standard acceptance limits. All other validation parameters were performed by following respective ICH guidelines.","PeriodicalId":8505,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"46 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138967383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of the Electronic Structure of Para-Substituted Benzaldehyde Benzohydrazone on Its Antimicrobial Activity: A DFT Analysis 对取代苯甲醛腙的电子结构对其抗菌活性的影响：DFT 分析

Asian Journal of Chemical Sciences Pub Date : 2023-12-12 DOI: 10.9734/ajocs/2023/v13i6275

Maurice N’bouke, Sèlonou Gautier Kankinou, Assongba Gaston Kpotin, J. Gómez-Jeria, Salomé D. S. Kpoviessi, Guy Y. S. Atohoun

{"title":"Effect of the Electronic Structure of Para-Substituted Benzaldehyde Benzohydrazone on Its Antimicrobial Activity: A DFT Analysis","authors":"Maurice N’bouke, Sèlonou Gautier Kankinou, Assongba Gaston Kpotin, J. Gómez-Jeria, Salomé D. S. Kpoviessi, Guy Y. S. Atohoun","doi":"10.9734/ajocs/2023/v13i6275","DOIUrl":"https://doi.org/10.9734/ajocs/2023/v13i6275","url":null,"abstract":"Bacillus subtilis is a bacterium that has demonstrated its efficacy across various domains, including industry, agriculture, and commerce, owing to its protective, inhibitory, and biological mechanisms against specific microbes. However, at high concentrations, it can lead to food poisoning and severe infections, resulting in symptoms such as diarrhea and vomiting. Bacterial spores produced by Bacillus subtilis can induce conditions like gas gangrene and tetanus. In this context, benzohydrazones are recognized for their antimicrobial activity, particularly against Bacillus subtilis. This study aims to elucidate the relationship between the electronic structure of para-substituted benzaldehyde benzohydrazone derivatives and their antimicrobial activity. This leads to the proposal of a 2D pharmacophore for predicting the antibacterial activity of these derivatives. The quantitative structure-activity relationship (QSAR) approach employed is the KPG method. The electronic structures were optimized using the density functional theory (DFT) method with the B3LYP functional and the 6-31G (d,p) basis set. Charge and local molecular orbitals were considered in the optimization process. The resulting prediction equation (R=98.95%, R²=97.91%, Adjusted R²=96.76%, F(5,9)=84.52) derived from multiple linear regression provides the basis for the proposed 2D pharmacophore. This equation shows that antimicrobial activity of benzohydrazone derivative is on charge and orbital controlled. This pharmacophore holds potential utility in designing new molecular structures with enhanced activity against Bacillus subtilis.","PeriodicalId":8505,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"47 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139008084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrochemically Generated Aluminum-Species for Remediation of Waste Water Containing 2, 4-Dichlorophenol 电化学生成的铝--用于修复含有 2，4-二氯苯酚的废水

Asian Journal of Chemical Sciences Pub Date : 2023-12-04 DOI: 10.9734/ajocs/2023/v13i6274

H. Simol, R. A. Jahan

引用次数: 0

Lactic Acid-Proline Solvent Pretreatment of CS: Effects of Process Variables on Glucan, Xylan, and Lignin Composition 乳酸-脯氨酸溶剂预处理 CS：工艺变量对葡聚糖、木聚糖和木质素成分的影响

Asian Journal of Chemical Sciences Pub Date : 2023-12-02 DOI: 10.9734/ajocs/2023/v13i6272

Onyelucheya, C. M., Nwabanne, J. T.

{"title":"Lactic Acid-Proline Solvent Pretreatment of CS: Effects of Process Variables on Glucan, Xylan, and Lignin Composition","authors":"Onyelucheya, C. M., Nwabanne, J. T.","doi":"10.9734/ajocs/2023/v13i6272","DOIUrl":"https://doi.org/10.9734/ajocs/2023/v13i6272","url":null,"abstract":"The aim of this study is to investigate the effect of temperature, duration, and water dilution on the composition of glucan, xylan, and lignin in cowpea shells (CS) pretreated with a neat and diluted Lactic acid-proline solvent. The composition of glucan, xylan, and lignin was analyzed using the NREL method. The highest xylan removal (12%) was achieved after a 6-hour pretreatment at 150°C, while 11.35% lignin removal was observed after 5 hours at the same temperature. The most significant increase in glucan content, reaching 78.3 %, was observed after 4 hours at 150°C using a 2.5% (w/w) water-diluted solvent. Comparing the effect of the neat solvents and diluted solvents it can be concluded that while the neat solvent promoted the dissolution of xylan and lignin, the addition of water preserved glucan from the harshness of the pretreatment. Therefore, the decision to dilute a natural deep eutectic solvent before its application in biomass pretreatment depends on the desired product from biomass fractionation (lignin or a carbohydrate-rich material) and pretreatment temperature. These findings provide a foundation for further investigations into optimizing the entire process.","PeriodicalId":8505,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"111 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138607367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Collaborative Study: Greener Synthesis of Heterocyclic Compounds Using Rice Husk-Based Catalyst 合作研究：使用稻壳基催化剂更环保地合成杂环化合物

Asian Journal of Chemical Sciences Pub Date : 2023-11-22 DOI: 10.9734/ajocs/2023/v13i6271

Sourav Dey, Pranab Ghosh

{"title":"A Collaborative Study: Greener Synthesis of Heterocyclic Compounds Using Rice Husk-Based Catalyst","authors":"Sourav Dey, Pranab Ghosh","doi":"10.9734/ajocs/2023/v13i6271","DOIUrl":"https://doi.org/10.9734/ajocs/2023/v13i6271","url":null,"abstract":"An efficient, straight forward and sustainable synthetic procedures for the synthesis of few important class of bioactive heterocyclic compounds like dihydro-dichromeno-pyridine-6,8-diones, tetrahydrotetrazolo[5,1-b]quinazolinones and2,4-diaryl hexahydroquinoline-5-ones have been designed using a novel bio-degradable heterogeneous catalyst-sulphonated rice-husk (SRH). The greener catalyst has high porosity and high density of acid groups along with bio-degradable characteristics which has made it different and advantageous material for catalysis as compared to other conventional homogenous solid acid catalyst. We report primarily a new protocol for the synthesis of a group of biologically active compounds such as dihydro-dichromeno-pyridine-6,8-dione, tetrahydrotetrazolo[5,1-b]quinazolinone and2,4-diaryl hexahydroquinoline-5-ones derivatives using sulphonated rice husk (SRH) under greener condition. Operational simplicity, easy recovery of the product, metal free technique and reusability of the catalyst with excellent yield are the important and promising features of this procedure. The prepared solid heterogeneous catalyst was subjected for characterization using different spectroscopic techniques like FTIR, SEM, EDX, Powder XRD before its application for desired reaction.","PeriodicalId":8505,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"38 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139249506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential Renewable Energy Source from Nutmeg-Coconut Shell Waste in North Maluku, Indonesia 印度尼西亚北马鲁古省肉豆蔻椰子壳废弃物的潜在可再生能源

Asian Journal of Chemical Sciences Pub Date : 2023-11-21 DOI: 10.9734/ajocs/2023/v13i6270

Abulkhair Abdullah, Muhammad Zulfian A. Disi, Muhammad Fakhrur Rajih Hi. Yusuf, Mutmainnah

{"title":"Potential Renewable Energy Source from Nutmeg-Coconut Shell Waste in North Maluku, Indonesia","authors":"Abulkhair Abdullah, Muhammad Zulfian A. Disi, Muhammad Fakhrur Rajih Hi. Yusuf, Mutmainnah","doi":"10.9734/ajocs/2023/v13i6270","DOIUrl":"https://doi.org/10.9734/ajocs/2023/v13i6270","url":null,"abstract":"In 2019, North Maluku exported 54,470,489 kg of copra and 2,712,999 kg of nutmeg. The large export value of these two commodities shows that not a small amount of organic waste is produced per year. The high market demand for these two superior commodities will have an impact on the high production of waste generated. Nutmeg shells and coconut shells are dry organic waste. Although organic waste can decompose naturally, both wastes will take a long time to decompose compared to wet organic waste. Waste that is not handled properly will have a worse impact in the future. On the other hand, these wastes have excellent potential if utilized as a renewable energy source. In this study, briquettes were made from nutmeg shell charcoal (NSC) and coconut shell charcoal (CSC) as basic materials, while the adhesive used a 4 % starch solution. This study aims to obtain the optimum ratio of nutmeg shell and coconut shell mixture as raw material for briquettes. The ratio of AP:AK in the briquettes is as follows: Formula B1 (3:1); Formula B2 (1:1); and Formula B3 (1:3). The briquettes were evaluated with reference to SNI 01-6235-2000. The results of the briquette evaluation are as follows: Formula B1 (water content 7.21 %; volatile matter 36.28 %; ash content 7.50 %; calories 6219.07 cal/g); Formula B2 (water content 7.18 %; volatile matter 32.39 %; ash content 6.52 %; calories 6485.14 cal/g); and Formula B3 (water content 6.93 %; volatile matter 29.41 %; ash content 7.06 %; calories 6813.80 cal/g). Based on the briquette evaluation results, Formula B3 is the best quality briquette.","PeriodicalId":8505,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139251686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Estimation of Toxic Hexavalent Chromium (Cr6+) in Metal Components Present in Electronic and Electrical Materials with or without using Coordinating Ligands 使用或不使用配位体估算电子和电气材料中金属成分的有毒六价铬（Cr6+）含量

Asian Journal of Chemical Sciences Pub Date : 2023-11-16 DOI: 10.9734/ajocs/2023/v13i6269

G. Swarnabala, K. Suresh, B. Divya, A. Bharadwaj

{"title":"Estimation of Toxic Hexavalent Chromium (Cr6+) in Metal Components Present in Electronic and Electrical Materials with or without using Coordinating Ligands","authors":"G. Swarnabala, K. Suresh, B. Divya, A. Bharadwaj","doi":"10.9734/ajocs/2023/v13i6269","DOIUrl":"https://doi.org/10.9734/ajocs/2023/v13i6269","url":null,"abstract":"The aqueous solutions of toxic hexavalent chromium have been analyzed using diphenyl carbazide (DPC) dissolved in organic solvents as a coordinating ligand since early nineteen hundreds. The chemistry is not clear due to the formation of an unstable, suggested organometallic complex, which is only An intermediary. The structure of the same could not be determined or is hypothetical even today with a further suggested, molecular structure in which instead of pi bonded delocalization of benzene rings expected to be as in sandwich compounds, electron empty d-orbital of hexavalent chromium facilitating the electron transfer and giving the observed color of the obtained complex as in inner field coordinating complexes. The electrical and electronic equipment requires the estimation of hexavalent chromium up to ~0.2 % (~2000 ppm) present in high chromium containing solid matrix, with DPC using standard International Electro-technical Commission (IEC) method. However, the visible yellow color can be directly measured on UV-Vis spectrophotometer with the hexavalent chromium stripped or leached out into acidic aqueous solutions from these materials using the known IEC method for leaching. The presence of interfering ions is ruled out with the leaching procedure given in it. Therefore, the stability of these aqueous acidic solutions containing hexavalent chromium was checked for 16 days. So that direct measurement can be done without DPC. Screws, Fork Pivot Bore and Rat Trap Box containing hexavalent chromium were analyzed and compared with and without DPC. It is noted that the analysis of these materials can satisfactorily be achieved easily or simply without adding DPC on UV-Vis spectrophotometer or any other organic ligands or using high-end equipment such as Ion Chromatography (IC).","PeriodicalId":8505,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"30 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139270427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gravimetric and Electrochemical Assessments of the Corrosion Inhibition Potential of Cola nitida Seeds Extract on Mild Steel Surface in Hydrochloric Acid (HCl) Solution 硝酸可乐籽提取物在盐酸溶液中对低碳钢表面缓蚀电位的重量及电化学评价

Asian Journal of Chemical Sciences Pub Date : 2023-11-14 DOI: 10.9734/ajocs/2023/v13i6267

Mboso I. Obodom, Inemesit A. Akpan, Okon U. Abakedi

{"title":"Gravimetric and Electrochemical Assessments of the Corrosion Inhibition Potential of Cola nitida Seeds Extract on Mild Steel Surface in Hydrochloric Acid (HCl) Solution","authors":"Mboso I. Obodom, Inemesit A. Akpan, Okon U. Abakedi","doi":"10.9734/ajocs/2023/v13i6267","DOIUrl":"https://doi.org/10.9734/ajocs/2023/v13i6267","url":null,"abstract":" Mild steel corrosion inhibition in 1 M HCl solution by semi-pure seeds extracts of Cola nitida was investigated using gravimetric and electrochemical (potentiodynamic polarization) methods. The results obtained reveal that dichloromethane (DCM) semi-pure seeds extracts of C. nitida coded Mb4 and Mb5) inhibited mild steel corrosion in hydrochloric acid solution. The inhibition efficiency, by the gravimetric method, increased with increase in the extracts concentration but decreased with increase in temperature. The inhibition efficiency by the potentiodynamic polarization also increased with increase in extract concentration. The evaluated thermodynamic parameters revealed that the corrosion inhibition process was spontaneous and endothermic in nature. Potentiodynamic polarization measurements revealed that the extracts were mixed – type inhibitors since E_corrvalues were less than the threshold value of 85 mV. The adsorption of the extracts onto mild steel surface fitted the Temkin adsorption isotherm. Scanning electron micrographs revealed the formation of protective dense film on the steel surface in the presence of the extracts compared to the blank. Physical adsorption has been proposed for the adsorption of C. nitida seeds extracts onto mild steel surface.","PeriodicalId":8505,"journal":{"name":"Asian Journal of Chemical Sciences","volume":"24 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134953984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Topological Indices of Antibiotic Drugs used in Pneumonia Treatment with their QSPR Analysis and M-polynomial 肺炎治疗中使用的抗生素药物的拓扑指标及其 QSPR 分析和 M 多项式

Asian Journal of Chemical Sciences Pub Date : 2023-11-14 DOI: 10.9734/ajocs/2023/v13i6268

S. Nagarajan, G. Kayalvizhi

引用次数: 0