Asian Journal of Chemistry最新文献_第7页

A Review on Anthropogenic Biomass Burning: Emission of Aerosol Pollutants, Impact on Climate Change, Human Health and its Mitigation Strategies 关于人为生物质燃烧的综述：气溶胶污染物的排放、对气候变化和人类健康的影响及其缓解策略

Asian Journal of Chemistry Pub Date : 2024-02-28 DOI: 10.14233/ajchem.2024.31028

D. Satheesh, V. Muthulakshmi, A. Jagadesan, A. Venkatesan, K. Suresh, K. Parthipan, Savarinathan Maria Rayappan, G. Senthilkumar, S. Sudhahar

{"title":"A Review on Anthropogenic Biomass Burning: Emission of Aerosol Pollutants, Impact on Climate Change, Human Health and its Mitigation Strategies","authors":"D. Satheesh, V. Muthulakshmi, A. Jagadesan, A. Venkatesan, K. Suresh, K. Parthipan, Savarinathan Maria Rayappan, G. Senthilkumar, S. Sudhahar","doi":"10.14233/ajchem.2024.31028","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31028","url":null,"abstract":"Biomass burning is a complex process, encircling chemical and physical responses covering, transmission of mass and warmth. A large number of investigations were accumulated on the significant emissions from various kinds of anthropogenic biomass burning in the recent decade. In India, an increasing trend of biomass burning is an important cause to release a large volume of reactive gases with other impurities and intensify the level of invisible particles into the troposphere, which affects humans health and leads to the probable alteration of the weather and global climate. The present review looks at the interpretations for a diverse investigation of distinct body and monitoring interventions, pertinent to our country, relating to the significance of particulate matter emissions, sources of aerosols and their health implications. This study also discusses numerous persuaded investigations, conducted on the impact of aerosol, attributed to climate change and also points out precise matters such as spatio-temporal variability of fire occurrences detected in India. Furthermore, the present study reveals that substantial quantities of data, along with a variety of enhanced simulation models and investigational validations, are essential for the development of efficient mitigation strategies with the objective of protecting the environment of the Indian Peninsula.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"97 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140423793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design, Synthesis and Anticancer Activity of Novel Substituted (E)-2-Morpholinoquinoline- 3-carbaldehyde-O-((-1-aryl-1H-1,2,3-triazol-4-yl)methyl)oxime Derivatives 新型取代(E)-2-吗啉基喹啉-3-甲醛-O-((-1-芳基-1H-1,2,3-三唑-4-基)甲基)肟衍生物的设计、合成和抗癌活性

Asian Journal of Chemistry Pub Date : 2024-02-28 DOI: 10.14233/ajchem.2024.30734

Aruna Jyothi Chatla, J. Yerrabelly, Nagaraju Dharavath, Panga Shyam

引用次数: 0

Metalloproteomics: Unraveling the Metal Binding Proteins of Diverse Metal-Resistant Bacteria 金属蛋白质组学：揭示多种抗金属细菌的金属结合蛋白

Asian Journal of Chemistry Pub Date : 2024-02-28 DOI: 10.14233/ajchem.2024.31102

N. Jamunasri, Aswetha Iyer, M. L. Prabha, R. Issac, S. Murugan

{"title":"Metalloproteomics: Unraveling the Metal Binding Proteins of Diverse Metal-Resistant Bacteria","authors":"N. Jamunasri, Aswetha Iyer, M. L. Prabha, R. Issac, S. Murugan","doi":"10.14233/ajchem.2024.31102","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31102","url":null,"abstract":"The release of metals into the environment raises serious concerns about their harmful effects on both the wildlife and human health. The biosphere is experiencing with the pervasive presence of heavy metal pollutants such as arsenic (As), cadmium (Cd), mercury (Hg), lead (Pb), chromium (Cr), copper (Cu) and nickel (Ni), which pose significant environmental challenges. While certain metals are essential for regulating fundamental metabolic processes and upholding the overall physiology of microorganisms, excessive exposure to heavy metals can be detrimental to their survival and function. As a result of their remarkable adaptability, microorganisms, particularly bacteria such as Pseudomonas fluorescens, Escherichia coli, Serratia marcescens, Bacillus cereus and Alcaligenes sp., have evolved sophisticated defence mechanisms to combat the stress caused by heavy metals. One such process is the creation of metal-binding proteins (MBPs), which may bind and sequester metals, thus significantly lowering their toxicity in bacteria. Metalloproteomics, a subfield of metallomics, focuses on the discovery and characterization of such metal-binding proteins (MBPs) in metal-resistant bacteria, resulting in the opening of the doors for innovative bioremediation techniques and therapeutic treatments against bacterial diseases. This review explores the intriguing world of MBPs in metal-resistant bacteria and emphasizes their significant role in metal resistance, detoxification and homeostasis. Furthermore, metallochaperones in bacteria have been extensively studied using the metalloproteomic methodologies and techniques utilized in metal-binding proteins. This study also provides useful information on the interactions between these metallochaperones and different MBPs, which advances our understanding of how bacteria respond to exposure to such heavy metals.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"12 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140421147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anticancer Potential of Gold doped ZnO Nanoparticles Fabricated using Root Extract of Kigelia africana (Lam.) Benth. against Lung (A549), Melanoma (A375) and Epidermoid (A431) Cancer Cells 利用 Kigelia africana (Lam.) Benth.根提取物制备的掺金氧化锌纳米粒子对肺癌（A549）、黑色素瘤（A375）和表皮样癌（A431）细胞的抗癌潜力

Asian Journal of Chemistry Pub Date : 2024-02-28 DOI: 10.14233/ajchem.2024.30957

P. Prasada Rao, N. Usha Rani

{"title":"Anticancer Potential of Gold doped ZnO Nanoparticles Fabricated using Root Extract of Kigelia africana (Lam.) Benth. against Lung (A549), Melanoma (A375) and Epidermoid (A431) Cancer Cells","authors":"P. Prasada Rao, N. Usha Rani","doi":"10.14233/ajchem.2024.30957","DOIUrl":"https://doi.org/10.14233/ajchem.2024.30957","url":null,"abstract":"This study presents a simple, biocompatible and eco-friendly Au-doped ZnO nanoparticles were fabricated by employing root aqueous extract of Kigelia africana (Lam.) Benth. root as reducing, stabilizing and capping agent. The nanoparticles were identified by showing characteristic UV-visible wavelength maxima at 361 nm (ZnO NPs) and 569 nm (Au NPs). The nanoparticles possess polycrystalline structure with circular to oval in shape having 34 nm size that contains ~24.74 % and ~52.16 % of Au and Zn content. The FT-IR analysis confirmed the functional groups correspond to terpenoids, flavonoids and phenolics present in aqueous root extract of of Kigelia africana (Lam.) were actively participated in nanoparticles capping. The cytotoxic applicability of fabricated nanoparticles was assessed by performing MTT assay against human lung cancer (A549) cells, melanoma cancer (A375) cells and skin or epidermoid cancer (A431) cells. The nanoparticles were proved to show potential anticancer activity with IC50 concentration of 206.13 µg/mL, 152.73 µg/mL and 295.49 µg/mL against A549, A375 and A431 cell lines respectively. The IC50 concentration of nanoparticles in DPPH assay was noticed as 43.75 µg/mL, whereas 33.95 µg/mL and 81.10 µg/mL respectively noticed for standard and aqueous root extract suggest that the nanoparticles possess potential antioxidant capability. Based on findings, it was suggested that the fabricated Au-doped ZnO NPs were treated as promising biocompatible candidate that can having remarkable applicability in therapeutic applications.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"88 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140422784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oxacyanopyridine-Benzofuran Hybrids: Synthesis, in silico Toxicity Assessment, in vitro Antimicrobial Activity and Dual Target Docking Studies Oxacyanopyridine-Benzofuran Hybrids：合成、硅学毒性评估、体外抗菌活性和双靶点对接研究

Asian Journal of Chemistry Pub Date : 2024-02-28 DOI: 10.14233/ajchem.2024.31092

Bhargavi Posinasetty, Ashish Ashokkumar Jaiswal, Rajendra Prasad Yejjella, Hari Veluru, Kishore Bandarapalle, R. K. Kumarachari

{"title":"Oxacyanopyridine-Benzofuran Hybrids: Synthesis, in silico Toxicity Assessment, in vitro Antimicrobial Activity and Dual Target Docking Studies","authors":"Bhargavi Posinasetty, Ashish Ashokkumar Jaiswal, Rajendra Prasad Yejjella, Hari Veluru, Kishore Bandarapalle, R. K. Kumarachari","doi":"10.14233/ajchem.2024.31092","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31092","url":null,"abstract":"This study emphasizes the synthesis and characterization of a novel series of oxa cyano pyridine heterocyclic molecular hybrids (OCP 1-6), integrating pyridine and benzofuran motifs. Meticulously designed from 5-chlorosalicylaldehyde in a multistep process, the synthesized compounds were structurally confirmed through IR spectroscopy, 1H NMR spectroscopy, and mass spectrometry. Computational predictions highlighted diverse properties, including antitubercular and antibacterial attributes, bioactivity scores, toxicity profiles and potential molecular targets. In vitro assessments and Schrödinger docking simulations revealed binding affinities to enzymes viz. Mycobacterium tuberculosis enoyl-ACP reductase and Escherichia coli Topoisomerase IV. Compounds, particularly OCP 2, 3, 4 and 5, exhibited significant antitubercular and antibacterial activities in both in vitro assessments and docking simulations. This study underscores the substantial potential of the synthesized hybrids as promising candidates for further lead optimization, positioning them as valuable contributors to the development of pharmaceutical agents with heightened potency and enhanced safety profiles.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140418352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and Biological Evaluation of vicinal-Diaryl Pyrazole Ethyl Carboxylate Analogs as Antiproliferative Agent against Pancreatic Cancer 作为胰腺癌抗增殖剂的邻位二芳基吡唑甲酸乙酯类似物的合成与生物学评价

Asian Journal of Chemistry Pub Date : 2024-02-28 DOI: 10.14233/ajchem.2024.31173

Sandeep Singh, Rajeev Kumar Sharma, Aishwarya Singh, Manoj Garg, R. Ramajayam

引用次数: 0

Biogenic ZnO Nanoparticles Derived from Garcinia gummi-gutta Leaves: Synthesis, Characterization and its Multifaceted Applications 从藤黄树叶中提取的生物纳米氧化锌：合成、表征及其多方面应用

Asian Journal of Chemistry Pub Date : 2024-02-28 DOI: 10.14233/ajchem.2024.31059

J.T. Kurian, K. S. Joseph

引用次数: 0

Study of Thermophysical Properties of Binary Mixtures of 1,4-Butanediol + Cresols at Different Temperatures 不同温度下 1,4-丁二醇和甲酚二元混合物的热物理性质研究

Asian Journal of Chemistry Pub Date : 2024-02-28 DOI: 10.14233/ajchem.2024.30274

J. Srinivasu, K. Narendra, Ch. Kavitha, B. Subbarao

引用次数: 0

Efficacy of Quercetin and Kaempferol from Methanolic Extracts of Adiantum lunulatum Burm. F. and Polystichum acrostichoides as Antidiabetic Activity Adiantum lunulatum Burm.F. 和 Polystichum acrostichoides 的抗糖尿病活性

Asian Journal of Chemistry Pub Date : 2024-02-28 DOI: 10.14233/ajchem.2024.31106

T. Sravani, Sunitha Katta

{"title":"Efficacy of Quercetin and Kaempferol from Methanolic Extracts of Adiantum lunulatum Burm. F. and Polystichum acrostichoides as Antidiabetic Activity","authors":"T. Sravani, Sunitha Katta","doi":"10.14233/ajchem.2024.31106","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31106","url":null,"abstract":"In present investigation, the aerial parts of two fern species viz. Polystichum acrostichoides (PA) and Adiantum lunulatum (AL) were used to evaluate the potent antidiabetic activity. Methanol solvent was used for extraction by soxhlation method followed by LC-MS analysis to identify the presence of compounds in both the extracts. Further, isolation of the major compounds was carried out and characterized by IR, mass and NMR techniques. Thereafter, in vitro α-amylase inhibitory activity for both the extracts was determined by comparing with acarbose as standard. Thereafter, α-glucosidase inhibition activity followed by glucose uptake was studied using L6 cell line study. Practical yield for both the fern extracts was calculated and observed A. lunulatum extract showed more yield (7 g) than P. acrostichoides (3 g). Based on the analytical data, isolated compound was identified as quercetin and kaempferol from the A. lunulatum and P. acrostichoides extracts, respectively. A. lunulatum extract even showed better dose dependent α-amylase inhibition and α-glucosidase inhibition activity than P. acrostichoides furthermore, L6 cell line study showed increased glucose uptake by A. lunulatum extract than P. acrostichoides extract when compared with standard insulin. Based on the findings, it appears that the both A. lunulatum and P. acrostichoides have the potential to be used as antidiabetic drugs due to presence of major isolated flavonoids i.e. quercetin and kaempferol as among the bioactive compounds. Antidiabetic efficacy was dosage dependent and A. lunulatum extract was more effective in inhibiting glucose uptake than P. acrostichoides extract.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"33 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140419050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and Characterization of CuO/SnO2 Nanocomposite for Catalytic Reduction of p-Nitrophenol 用于催化还原对硝基苯酚的 CuO/SnO2 纳米复合材料的合成与表征

Asian Journal of Chemistry Pub Date : 2024-02-28 DOI: 10.14233/ajchem.2024.31054

S. Lekshmi, P.V. Anjima, K.V. Anagha, K. Dhanasree, A. Abraham

引用次数: 0