Asian Journal of Chemistry最新文献_第4页

UHPLC-MS/MS Technique: Applications in Analytical Chemistry 超高效液相色谱-质谱/质谱技术：分析化学中的应用

Asian Journal of Chemistry Pub Date : 2024-03-30 DOI: 10.14233/ajchem.2024.31383

Hamid Khan

引用次数: 0

Isolation of Verimol G from Illicium verum Hook.f. Fruit and its Computational Prediction as Antimalarial Agent 从Illicium verum Hook.f.果实中分离出马来酚G并将其作为抗疟药物进行计算预测

Asian Journal of Chemistry Pub Date : 2024-03-30 DOI: 10.14233/ajchem.2024.31287

A.N. Kristanti, N. Aminah, T.C. Bramayudha, K.W. Mukharomah, A.P. Wardana, B. Ilham, Y. Takaya

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Adsorptive Removal of Methylene Blue Dye by Annealed Waste Foundry Sand 退火废铸造砂对亚甲蓝染料的吸附去除作用

Asian Journal of Chemistry Pub Date : 2024-03-30 DOI: 10.14233/ajchem.2024.31029

Chandrashekhar R. Patil, S. Patil, Anita K. Tawade, Bhagyashri B. Kambale, S. Tayade, Sharad S. Patil, D. N. Zambare

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Design, Synthesis, Characterization and Antitubercular Activity of Novel Benzimidazole Mannich Base Derivatives 新型苯并咪唑曼尼希碱衍生物的设计、合成、表征和抗结核活性

Asian Journal of Chemistry Pub Date : 2024-03-30 DOI: 10.14233/ajchem.2024.31314

C. Gopi, M. Dhanaraju, Konatham Pranusha, Thiyagarajan Deepan, AR Magesh, Dhanaraju Kavitha

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Production of Methane and Hydrogen from Mild-Strength Industrial Wastewater 利用低强度工业废水生产甲烷和氢气

Asian Journal of Chemistry Pub Date : 2024-03-30 DOI: 10.14233/ajchem.2024.30618

Md. Nurul Islam Siddique, Az Zahirah, Md. Zamri Bin Ibrahim, N. Ali, Shahrul Bin Ismail, Wan Sani Wan Nik, M. R. K. Chowdhury

{"title":"Production of Methane and Hydrogen from Mild-Strength Industrial Wastewater","authors":"Md. Nurul Islam Siddique, Az Zahirah, Md. Zamri Bin Ibrahim, N. Ali, Shahrul Bin Ismail, Wan Sani Wan Nik, M. R. K. Chowdhury","doi":"10.14233/ajchem.2024.30618","DOIUrl":"https://doi.org/10.14233/ajchem.2024.30618","url":null,"abstract":"Over the past two decades, fossil fuel reserves have sharply shrunk, which has resulted in a global fall in energy sources. Alternative carbon-neutral renewable energy sources have caught the interest of experts due to the erratic nature of energy prices and their severe ecological effects. The treatment plant’s mild-strength effluent from an equalization tank at an industrial factory was used in this study to generate hydrogen and methane. This mild-strength effluent had a chemical oxygen demand (COD) content of 2.8 ± 1.0 g COD/L. A double stage anaerobic digestion system’s hydrogen-generating digester was run at a hydraulic retention time of 8 h while the methane-generating digester was run at a hydraulic retention time of 24 h. The highest methane production rate (MPR), methane yield (MY), methane content and COD elimination were, in order, 71 ± 30 mL/L-d, 57 ± 10 mL/g COD, 90 ± 1% and 77%, respectively. In this experiment, energy efficiency was assessed using the following criteria: Maximum heating was at a value of 2.1 × 108 kcal/y. Utilizing energy-equivalent coal, natural gas, or fuel reduced annual carbon emissions by 8.7 × 104 kg CO2/y, 5.1 × 104 kg CO2/y and 7.1 × 104 kg CO2/y, respectively.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"42 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140364235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Advances in Anti-Urease Activity of Schiff Bases and their Metal Complexes 希夫碱及其金属复合物抗尿素酶活性的最新研究进展

Asian Journal of Chemistry Pub Date : 2024-03-30 DOI: 10.14233/ajchem.2024.31333

Neelam Yadav, Sonu Chauhan, Sarita Sangwan, Ravi Kumar, Deepak

引用次数: 0

CuI Promoted Efficient Synthesis and Antimicrobial Activity of Substituted 8,8-Dimethyl-5-phenyl-2-(pyrazin-2-yl)-5,7,8,9-tetrahydro-6H-[1,3,4]thiadiazolo[2,3-b]quinazolin-6-one CuI 促进取代型 8,8-二甲基-5-苯基-2-（吡嗪-2-基）-5,7,8,9-四氢-6H-[1,3,4]噻二唑并[2,3-b]喹唑啉-6-酮的高效合成和抗菌活性

Asian Journal of Chemistry Pub Date : 2024-03-30 DOI: 10.14233/ajchem.2024.30890

N. S. Khadgamala, V. N. Rao, K. Apparao, B. V. Durgarao, B. S. Diwakar, N. Rao

引用次数: 0

Synthesis and Characterization of Biopotent Transition Metal Complexes of Schiff Base 2-{(1)-1-[2-(1,3-Benzothiazol-2-yl)hydrazinylidene]ethyl}-6,10b-dihydro-3H-benzo[f]chromen-3-one and their Biological Evaluation 希夫碱 2-{(1)-1-[2-(1,3-苯并噻唑-2-基)亚肼]乙基}-6,10b-二氢-3H-苯并[f]色烯-3-酮的生物活性过渡金属配合物的合成与表征及其生物学评价

Asian Journal of Chemistry Pub Date : 2024-03-30 DOI: 10.14233/ajchem.2024.31148

Shridhar P. Melkeri, P. Naik, N. Satyanarayan, I. Pushpavathi, G. Krishnamurthy, Prabhakar W. Chavan

{"title":"Synthesis and Characterization of Biopotent Transition Metal Complexes of Schiff Base 2-{(1)-1-[2-(1,3-Benzothiazol-2-yl)hydrazinylidene]ethyl}-6,10b-dihydro-3H-benzo[f]chromen-3-one and their Biological Evaluation","authors":"Shridhar P. Melkeri, P. Naik, N. Satyanarayan, I. Pushpavathi, G. Krishnamurthy, Prabhakar W. Chavan","doi":"10.14233/ajchem.2024.31148","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31148","url":null,"abstract":"Three transition metal(II) complexes (M = Co/ Zn/Pd) were synthesized by using a newly synthesized Schiff base ligand 2-{(1E)-1-[2-(1,3-benzothiazol-2-yl)hydrazinylidene]ethyl}-6,10b-dihydro-3H-benzo[f]chromen-3-one (L) by conventional method. The structure of the compounds were determined by physical and analytical techniques like UV-visible, FT-IR, 1H and 13C NMR and mass spectroscopic techniques and the crystallinity and inter-planar distance of the complexes were confirmed by XRD. The electron density in HOMO and LUMO was determined by DFT studies. The studies of electronic spectra and measurements of magnetic susceptibility suggest that Co(II) complex shows an octahedral geometry, Pd(II) complexes show square planar geometry and (ZnL2Cl2) complex shows tetrahedral geometry. The molar conductivity results suggested the non-electrolytic nature of the metal(II) complexes. The synthesized compounds was tested against antibacterial activity for Gram-positive and Gram-negative bacteria. The molecular docking study demonstrated that the ligand and its metal(II) complexes possess antibacterial and anticancer properties, and the results showed that the compounds were effective against the microorganisms that were examined. Furthermore, the results found that metal(II) complexes provided enhanced immunity against cancer cell lines.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"57 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140362683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trace Level Quantification of Genotoxic Impurities through Atmospheric Pressure Chemical Ionization (APCI) Coupled with Triple Quardrapole Analyzer in Combination Diabetic Drug Product 通过常压化学电离 (APCI) 和三重四极杆分析仪对糖尿病联合用药产品中的基因毒性杂质进行痕量定量

Asian Journal of Chemistry Pub Date : 2024-03-30 DOI: 10.14233/ajchem.2024.31178

Mehul Pathak, Dhara D. Patel, Dalip Sharma, Avineesh Singh, Suresh Agrawal

{"title":"Trace Level Quantification of Genotoxic Impurities through Atmospheric Pressure Chemical Ionization (APCI) Coupled with Triple Quardrapole Analyzer in Combination Diabetic Drug Product","authors":"Mehul Pathak, Dhara D. Patel, Dalip Sharma, Avineesh Singh, Suresh Agrawal","doi":"10.14233/ajchem.2024.31178","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31178","url":null,"abstract":"N-Nitrosamine impurities have been found in several drug products, showing a concern for regulatory aspects. The study presents the development and validation of a sensitive LC-MS/MS method for detecting eight nitrosamines in vildagliptin and metformin drug products. The developed method was specific and linearity was ranged 3.53-55.92 ppb for NDMA, 3.18-50.37 ppb for NMBA, 0.97-15.41 ppb for NDEA, 0.98-15.52 ppb for NEIPA, 1.00-15.86 ppb for NDIPA, 0.98-15.46 ppb for NDBA, 0.98-15.58 ppb for NMPA and 0.7-15.32 ppb for NDPA with correlation coefficient (r) was more than 0.98 and square of correlation coefficient (r2) was found to be greater than 0.96. The LOQ were obtained in the range of 0.97-3.53 ppb with %RSD in the range of 2.5-10.9% for eight nitrosamines showed good sensitivity. Accuracy was found in the range of 98.63 ± 5.77-125.17 ± 3.68% at LOQ level, 74.77 ± 0.83-88.17 ± 0.15% at 50% level, 79.93 ± 8.47-89.00 ± 0.61% at 100% level and 74.67 ± 2.31-84.03 ± 0.93% at 150% level for the eight nitrosamine impurities that were well within acceptance criteria of not less than 70% and not more than 130%. The method validation results demonstrated that the method is precise, accurate and linear, can be applied to quantify the nitrosamines in vildagliptin and metformin drug products.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"56 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140363171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, Characterization, in vitro Biological Evaluation of a Series of Benzothiazole Amides as Antibacterial Agents 作为抗菌剂的一系列苯并噻唑酰胺的合成、表征和体外生物学评价

Asian Journal of Chemistry Pub Date : 2024-03-30 DOI: 10.14233/ajchem.2024.31299

Hadyah Mohammed Alazmaa, V. Avupati, Carolina Santiago

{"title":"Synthesis, Characterization, in vitro Biological Evaluation of a Series of Benzothiazole Amides as Antibacterial Agents","authors":"Hadyah Mohammed Alazmaa, V. Avupati, Carolina Santiago","doi":"10.14233/ajchem.2024.31299","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31299","url":null,"abstract":"A series of benzothiazole amides (VH01-06) were synthesized by using modified Schotten-Baumann reaction conditions, all the resultant compounds were obtained in good yields and purity. The molecular structure of the compounds was characterized using physical and spectral methods. The structures of the compounds were consistent with the analytical data obtained for FT-IR, 1H NMR, 13C NMR and HRMS ESI-Mass spectroscopic techniques. Further, compounds were subjected to the in vitro antibacterial activity screening against various strains that includes Gram-positive bacteria (methicillin-resistant Staphylococcus aureus (MRSA) ATCC 3359 and methicillin-sensitive Staphylococcus aureus (MSSA) ATCC 2592) and Gram-negative bacteria (Escherichia coli J53 R1, Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 10031 and Klebsiella pneumonia BAA-1075). Based on the biological screening results, compounds VH01-06 were found to possesses limited antibacterial properties against selected strains, since the recorded activity was found at 100 µM concentration. While compound VH05 displayed specific activity against E. coli ATCC 25923 at 200 µg/mL.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"43 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140364158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0