Shaik Harun Rasheed, Sayyad Mustak, Chandan Mohanty, Ravi Kumar Vakkalagadda, Sandip Sen
{"title":"Multi Receptor Targeting of Potential Bioactive Compound Obtained from Chloroform Extract of Asparagus racemosus by GC-MS Analysis: A in silico Based Approach","authors":"Shaik Harun Rasheed, Sayyad Mustak, Chandan Mohanty, Ravi Kumar Vakkalagadda, Sandip Sen","doi":"10.14233/ajchem.2024.31671","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31671","url":null,"abstract":"Previous reports indicate that the medicinal plants and their components have been utilized for treating diverse conditions since antiquity. Asparagus racemosus, in particular, demonstrates a broad spectrum of therapeutic possibilities. This study aimed to underscores the potential bioactive compounds found within the chloroform extract of Asparagus racemosus. Gas-chromatography employed to identify the presence of various molecules, while mass spectrometry and FTIR analysis validated their molecular structures. The molecules were analyzed to assess its suitability as a therapeutic candidate, their biological activity and predicted targets using in silico techniques. The chloroform extract stands out as the richest reservoir of carbohydrates and steroidal alkaloids. Molecule (5β)-pregnane-3,20β-diol, 14α,18α-[4-methyl-3-oxo-(1-oxa-4-azabutane-1,4-diyl)]diacetate was found in the highest concentration (42.28 %). The identified molecule is a steroidal alkaloid in nature and the computational analysis revealed promising drug-like properties and therapeutic potential for the investigated molecule.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"29 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141802796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Molecular Interaction in Ternary Systems of Tri-n-octylamine/Tri-n-butyl Phosphate/Octanoic Acid with n-Hexane and 1-Hexanol at Different Temperatures","authors":"R.K. Sahu, S. Pradhan, S. Mishra","doi":"10.14233/ajchem.2024.31992","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31992","url":null,"abstract":"Density, dielectric constant and refractive index were measured for three ternary systems viz. tri-n-octylamine/tri-n-butyl phosphate/octanoic acid (TOA/TBP/OA), with n-hexane and 1-hexanol at T = 303.15, 308.15 and 313.15 K. Derived properties like molar volume, molar polarization, molar refraction and excess parameters were calculated from the measured density, dielectric constant and refractive index values, respectively. The excess values were also calculated with the Redlich-Kister polynomial and the fitting coefficients and standard deviations are reported. The density of the ternary mixtures increased with the increase in the mole fraction of the solute and decreased with the rise of temperature. The negative dielectric constant values for all the systems indicate a reduction in effective dipoles due to the dipolar self-association of the polar molecules. The FT-IR spectra of all the systems indicate a feeble interaction among the extractants, diluent and modifier.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"6 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141803417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Priya, N. Manoj, K. L. Prasanth, E. Nissam, S. Sugunan, K.M. Rajesh
{"title":"Combination of Sonochemical Synthesis and Calcination of Graphene-TiO2 Nanocomposite for Efficient Photocatalytic Degradation of Methyl Orange Dye","authors":"S. Priya, N. Manoj, K. L. Prasanth, E. Nissam, S. Sugunan, K.M. Rajesh","doi":"10.14233/ajchem.2024.31449","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31449","url":null,"abstract":"In this work, a nanostructured graphene-TiO2 nanocomposite was prepared by modified sonochemical method followed by calcination process at 400 ºC and characterized by X-ray diffraction, transmission electron microscopy, UV visible spectroscopy, IR spectroscopy and X-ray photoelectron spectroscopy. The photocatalytic activity of the prepared sample was evaluated by photocatalytic degradation of methyl orange dye. On analysis, visible light absorption was found to be increased for the nanocomposite rather than pure TiO2. About 75% degradation efficiency was exhibited by the prepared GT2 composite under sunlight irradiation.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141805140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unveiling the Issues on Water Pollution Narrative, Focus on Quality and Quantity Dynamic: Mini Review","authors":"Gloria U. Fayomi, E. Onyari","doi":"10.14233/ajchem.2024.31351","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31351","url":null,"abstract":"The 2015 United Nations Sustainable Development Goal 6 (SDG 6) aims to solve the global water concerns by emphasising access to safe drinking water, sanitation and wastewater management. Significant populations, however, continue to lack these basics, contributing to child mortality and waterborne illnesses. Water pollution exacerbates the worldwide water problem, having an impact on ecosystems and human health. This study delves into the intricate problems of water pollution, including its causes, health consequences and ecological disruptions. It also looks at worldwide policies and legislative attempts like the Safe Drinking Water Act and international mandates like the Water Framework Directive. These regulations indicate a shift towards more comprehensive approaches, such as Integrated Water Resources Management (IWRM), which strike a balance between fairness, ecological integrity and efficiency principles.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"38 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141805308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N.A. Kaushi Aloka, R. Jayasinghe, G. Priyadarshana, A. Nilmini
{"title":"Influence of Fibre Loading on the Physico-Mechanical Properties of Water Hyacinth (Eichhornia crassipes) Fibre Reinforced Polyethylene Composites","authors":"N.A. Kaushi Aloka, R. Jayasinghe, G. Priyadarshana, A. Nilmini","doi":"10.14233/ajchem.2024.31699","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31699","url":null,"abstract":"Water hyacinth (Eichhornia crassipes), an invasive aquatic weed, threatens ecosystems by rapidly spreading across water surfaces. However, this study investigates its potential as a fibre source for various applications. Decorticated water hyacinth fibres were mixed into a polyethylene matrix at different weight ratios (0%, 5%, 7.5%, 10% and 12.5%). The resulting composites underwent thorough physico-mechanical characterization. Tensile strength showed a non-linear relationship with fibre content with the 5% fibre composite exhibiting the highest strength at 8.6 MPa. Fractographic analysis revealed the strength reduction was due to poor interfacial bonding. Flexural and impact strength increased with higher fibre content, peaking at 10.07 MPa and 26 J m-1, respectively, in the 12.5% fibre composite. Composite hardness rose from 43.9 to 45.5 Shore D with fibre inclusion, while density decreased. Moisture absorption and flammability increased with fibre content. This study highlights the potential of water hyacinth fibre reinforcement in polymer composites.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"45 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141805716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enhanced Photocatalytic Methylene Blue Degradation and Chromium(VI) Photoreduction under Sunlight by Fe3O4@rGO@CeO2/Nd2O3 as Magnetic Recyclable Photocatalyst","authors":"Vishal A. Naik, Vikas A. Thakur","doi":"10.14233/ajchem.2024.31895","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31895","url":null,"abstract":"A significant global concern is in the easy separation, recyclability and reusability of photocatalysts in industrial wastewater treatment applications. Therefore, in this study, the synthesis of magnetically separatable Fe3O4@rGO@CeO2/Nd2O3 photocatalyst using a one-step solvothermal method is reported, which overcomes all these challenges. A binary lanthanide oxides CeO2/Nd2O3 anchored on rGO-wrapped Fe3O4 core-shell magnetic nanoparticles. The synthesized magnetic photocatalyst nanocomposite has been characterized using XRD, FESEM, EDX, HRTEM, TGA-DTA-DSC, VSM, FTIR and UV-visible spectrophotometer. In this work, the Fe3O4 synthesized by solvothermal technique achieved the highest saturation magnetization (MS), 101.84 emu/g. The results showed that Fe3O4@rGO@CeO2/Nd2O3 photocatalyst had more excellent stability up to 880 ºC confirmed by TGA-DTA-DSC analysis and efficient potential for the degradation of methylene blue by photo-Fenton reaction and reduction of Cr(VI) in formic acid under sunlight. The prepared photocatalyst efficiently degrades 98% of methylene blue in 50 min at neutral pH and quick photoreduction of Cr(VI) of 99% takes place within 40 min. After six cycles, the repeatability of the photocatalytic activity exhibited just a slight reduction in catalytic efficiency for degradation of methylene blue and photoreduction of Cr(VI).","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"27 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141805949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jirawan Noichan, Nithima Khaorapapong, T. Senawong, Panawan Moosophon
{"title":"Evaluation of Anticancer Activity of Organo-Montmorillonites and their Plumbagin-Nanohybrids","authors":"Jirawan Noichan, Nithima Khaorapapong, T. Senawong, Panawan Moosophon","doi":"10.14233/ajchem.2024.31672","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31672","url":null,"abstract":"Plumbagin is a naphthoquinone derivative obtained from medicinal plant and displayed cytotoxic activity against several cancer cells. To increase the cytotoxicity of plumbagin on cancer cell lines, it was adsorbed by organo-montmorillonites, used as an adsorbent and prepared by the ion-exchange reaction between three quaternary ammonium surfactants and sodium ion in montmorillonite. Three plumbagin-nanohybrids were successfully synthesized by adsorption of plumbagin in the interlayer space of the organo-montmorillonites and accessed antiproliferation effect on three cancer cells including human colon cancer, human cervical cancer and human breast cancer cell lines and a non-cancer cell line. The organoclays and plumbagin-nanohybrids were characterized by X-ray diffraction, IR and CHN analysis. The combination index (CI) value was used to determine the degree of organo-montmorillonites and plumbagin interaction, indicating a synergistic cytotoxicity between plumbagin and all three organo-montmorillonites on MCF-7 cell proliferation, while they showed additive effect on Vero cell.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"108 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141802260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Lawrance, D. L. Rose Mary, A. E. S. Felicita, P. M. Arockianathan
{"title":"Physico-chemical Characteristics of Keratin Extracted from Three Commercial Bird Feathers and their Antibacterial Activity","authors":"A. Lawrance, D. L. Rose Mary, A. E. S. Felicita, P. M. Arockianathan","doi":"10.14233/ajchem.2024.31728","DOIUrl":"https://doi.org/10.14233/ajchem.2024.31728","url":null,"abstract":"Commercial bird feathers waste is a major environmental concern that must be modified in an eco-friendly way into value added products. In this study, keratin samples extracted from three commercial bird feathers (broiler, Turkey and country chicken) were compared and characterized. The chemically extracted keratin samples were analyzed using Kjeldahl method, SDS-PAGE, HPLC, SEM, FTIR, XRD techniques and also evaluated its antibacterial activity. The extracted samples showed low molecular weight and confirmed its secondary structure by FTIR spectra. The amino acids composition was similar in all keratin samples whereas the amino acids content was found to be higher in broiler keratin. All the samples retain their chemical structure and crystallinity. The antibacterial activity of keratin samples was identified by a well diffusion method and the zone of inhibition was found to be greater for broiler keratin compared to other samples. Thus, broiler feathers keratin can be utilized in future for more protein derived products due to its higher protein content and antibacterial activity.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"24 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141803057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Durga Bhavani, Ch. Kavitha, K. Narendra, P. Bhavani
{"title":"Density, Speed of Sound and Derived Properties of Binary Mixtures Propiophenone + Butoxyethanol at T = (303.15, 308.15, 313.15 and 318.15) K","authors":"M. Durga Bhavani, Ch. Kavitha, K. Narendra, P. Bhavani","doi":"10.14233/ajchem.2024.30932","DOIUrl":"https://doi.org/10.14233/ajchem.2024.30932","url":null,"abstract":"The current study reports the experimental density (ρ) and sound speed (u) values for binary mixes of liquids propiophenone + 2-butoxyethanol at atmospheric pressure (0.1 MPa) and T = (303.15, 308.15, 313.15 and 318.15) K for the full spectrum of composition. densities and sound speed measurements from experiments have been used to estimate excess isentropic compressibility (κsE), excess molar volume (VEm), excess molar isentropic compressibility (KEs,m), excess isobaric thermal expansivity (αEp) and excess sound speed (uE). The Redlich-Kister polynomials were used to correlate excess parameters. Excess partial molar volume quantities (VEm,1 and VEm,2) at infinite dilution and their limiting values (V0Em,1 and V0Em,2) have been analytically determined using Redlich-Kister polynomials from the experimental density data. The results have been analyzed in light of strength and interactions among molecular entities scope and extent prevalent in these mixtures.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"43 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140362994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rahul P. Kedar, M. Bhalerao, Yogeshsing N. Rajput, Ravindra D. Kulkarni
{"title":"Development of Novel Cost Efficient Process for Extraction of Sterols and Tocopherols from Wild Plant Seed","authors":"Rahul P. Kedar, M. Bhalerao, Yogeshsing N. Rajput, Ravindra D. Kulkarni","doi":"10.14233/ajchem.2024.29031","DOIUrl":"https://doi.org/10.14233/ajchem.2024.29031","url":null,"abstract":"The present work focuses on the compositional characterization of tamarind and sea buckthorn seed oils, which have a wide range of uses in the cosmetic, pharmaceutical and food sectors. The characterization includes the analysis of tocopherols, sterols and fatty acid profile in both oils. The tamarind and sea buckthorn oils were converted to fatty acid methyl ester and the fatty acid composition was analyzed by using gas chromatography technique. The quantitative and qualitative analysis of tocopherols performed using high performance liquid chromatography. This study reveals that the oil samples consist of a variety of saturated and unsaturated fatty acids, such as myristic acid (0 and 0.4%), palmitic acid (11 and 30.5%), palmitoleic (0 and 39.6%) stearic acid (0 and 0.5%), oleic acid (18.3 and 26.1%), linoleic acid (45.8 and 2.1%), linolenic acid (4.1% and 0.5%), arachidic acid (1.8% and 0%) behenic acid (9.6 and 0%) and lignoceric acid (9.4 and 0%). Additionally, the analysis detects various tocopherol components, including α-tocopherol (21.4 and 32.6%), β-tocopherol (14.49 and 7.24%), γ-tocopherol (53.72 and 45.66%), δ-tocopherol (9.64 and 9.11%) and α-tocotrienol (0 and 5.13%) in tamarind and sea buckthorn oil, respectively.","PeriodicalId":8494,"journal":{"name":"Asian Journal of Chemistry","volume":"53 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140361781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}