Asian journal of anesthesiology最新文献

筛选
英文 中文
What Corner Pocket? Critical Examination of a Supraclavicular Sonographic View. 什么角袋?锁骨上声像图的关键检查。
Asian journal of anesthesiology Pub Date : 2026-03-01 DOI: 10.6859/aja.202603/PP.0001
Jackson Harley, Patrick Halliday, Richard K Kim
{"title":"What Corner Pocket? Critical Examination of a Supraclavicular Sonographic View.","authors":"Jackson Harley, Patrick Halliday, Richard K Kim","doi":"10.6859/aja.202603/PP.0001","DOIUrl":"https://doi.org/10.6859/aja.202603/PP.0001","url":null,"abstract":"","PeriodicalId":8482,"journal":{"name":"Asian journal of anesthesiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147484327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Fascia Iliaca Compartment Blocks for Pain Relief After Hip Arthroplasty Using Ropivacaine and Dexamethasone. 髂筋膜间室阻滞对罗哌卡因和地塞米松髋关节置换术后疼痛缓解的效果。
Asian journal of anesthesiology Pub Date : 2025-11-28 DOI: 10.6859/aja.202511/PP.0001
Quang Minh Pham, Hoang Son Pham, Thanh Hien Nguyen, Huu Tu Nguyen
{"title":"Effectiveness of Fascia Iliaca Compartment Blocks for Pain Relief After Hip Arthroplasty Using Ropivacaine and Dexamethasone.","authors":"Quang Minh Pham, Hoang Son Pham, Thanh Hien Nguyen, Huu Tu Nguyen","doi":"10.6859/aja.202511/PP.0001","DOIUrl":"https://doi.org/10.6859/aja.202511/PP.0001","url":null,"abstract":"<p><strong>Background: </strong>Fascia iliaca compartment block (FICB) is one of the regional blocks used to reduce postoperative pain after total hip arthroplasty (THA). Administration of dexamethasone in the loading dose might lengthen pain-free duration and reduce anesthetic consumption.</p><p><strong>Methods: </strong>Sixty patients undergoing THA with spinal anesthesia and patient-controlled FICB were randomly assigned to receive either 20 mL of 0.25% ropivacaine with 8 mg dexamethasone (Group D, n = 30) or 20 mL of 0.25% ropivacaine alone (Group C, n = 30). Postoperative pain scores, analgesic use, and side effects were assessed over 72 hours.</p><p><strong>Results: </strong>Postoperative visual analogue scale scores did not differ significantly between groups. The time to first bolus was longer in Group D than in Group C (407.10 ± 305.68 vs. 308.63 ± 212.99 minutes; P < 0.05). Total ropivacaine consumption over 72 hours was lower in Group D (210.33 ± 79.64 mg) compared to Group C (288.00 ± 91.32 mg), with a similar reduction in bolus frequency (14.53 ± 7.96 vs. 22.30 ± 9.13). The incidence of adverse events, including quadriceps weakness, local effects, and other side effects, was low and comparable between groups.</p><p><strong>Conclusion: </strong>The addition of dexamethasone to ropivacaine for FICB after THA can significantly provide a longer duration of analgesia with a lower amount of anesthetic.</p>","PeriodicalId":8482,"journal":{"name":"Asian journal of anesthesiology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145660090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Long- Versus Short-Acting Angiotensin II Receptor Antagonists and Hypotension During Anesthesia Induction: A Retrospective Study. 长效与短效血管紧张素 II 受体拮抗剂与麻醉诱导期间低血压之间的关系:一项回顾性研究。
Asian journal of anesthesiology Pub Date : 2024-12-20 Epub Date: 2024-09-16 DOI: 10.6859/aja.202403_62(1).0004
Masahiro Kuroki, Hiroto Suzuki, Yu Onodera, Masaki Nakane, Kaneyuki Kawamae
{"title":"Association Between Long- Versus Short-Acting Angiotensin II Receptor Antagonists and Hypotension During Anesthesia Induction: A Retrospective Study.","authors":"Masahiro Kuroki, Hiroto Suzuki, Yu Onodera, Masaki Nakane, Kaneyuki Kawamae","doi":"10.6859/aja.202403_62(1).0004","DOIUrl":"10.6859/aja.202403_62(1).0004","url":null,"abstract":"<p><strong>Background: </strong>The withdrawal or continuation of angiotensin II receptor blockers (ARBs) before surgery continues to be debated. We hypothesized that this is because ARBs with different half-lives have not been studied individually. This retrospective study aimed to clarify whether the degree of hypotension during anesthesia induction differs among ARBs with different half-lives.</p><p><strong>Methods: </strong>We included patients who received general anesthesia with regular oral administration of telmisartan (group T) or valsartan (group V), which have half-lives of approximately 24 and 6 hours, respectively. The frequency of hypotension and vasopressor frequency and dose during anesthesia induction were compared between the two groups. At our hospital, ARBs were withdrawn on the day of surgery in all patients.</p><p><strong>Results: </strong>Groups T and V included 190 and 132 patients, respectively. Patient backgrounds in group V were significantly more strongly associated with the use of calcium channel blockers. No significant differences were observed in the use of other concomitant antihypertensive medications, cardiovascular complications, or renal function. The time during which the mean arterial blood pressure was < 60 mmHg during anesthesia induction was significantly greater in group T than in group V (11 min vs. 7 min, P=0.030). The proportion of patients who used vasopressors was significantly higher in group T than that in group V (74.2% vs. 56.0%, P < 0.001).</p><p><strong>Conclusion: </strong>Patients taking telmisartan showed more hypotensive during the induction of general anesthesia than those taking valsartan, even after withdrawal on the day of surgery.</p>","PeriodicalId":8482,"journal":{"name":"Asian journal of anesthesiology","volume":" ","pages":"28-38"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142279822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adverse Effects of Chemotherapy and the Interaction With Anesthesia: A Narrative Review. 化疗的不良反应及其与麻醉的相互作用:一个叙述性的回顾。
Asian journal of anesthesiology Pub Date : 2024-12-20 DOI: 10.6859/aja.202403_62(1).0003
Marina Ayres Delgado, Paul Holzmann Neto, André Luis Vieira Drumond, Geovana Torres de Souza, André Dos Santos Mendonça, Camila Gomes Dall'Aqua, Bruna Carvalho Oliveira, Bruno Vinícius Castello Branco, Samuel Loureiro Gontijo, David Ribeiro do Nascimento
{"title":"Adverse Effects of Chemotherapy and the Interaction With Anesthesia: A Narrative Review.","authors":"Marina Ayres Delgado, Paul Holzmann Neto, André Luis Vieira Drumond, Geovana Torres de Souza, André Dos Santos Mendonça, Camila Gomes Dall'Aqua, Bruna Carvalho Oliveira, Bruno Vinícius Castello Branco, Samuel Loureiro Gontijo, David Ribeiro do Nascimento","doi":"10.6859/aja.202403_62(1).0003","DOIUrl":"10.6859/aja.202403_62(1).0003","url":null,"abstract":"<p><p>Many cancer patients have their main tumors surgically removed with the goal of curing them, or as part of palliative care. When a patient receives general anesthesia, the side effects of the administered chemotherapy regimens must be considered, especially those that may have significant repercussions during anesthetic care. The aim of this study is to review the existing literature to identify adverse effects of chemotherapy and known interactions between chemotherapy and anesthetic drugs, analyze the mechanisms underlying these interactions, and discuss relevant clinical implications. This integrative review searched for articles using the search terms: chemotherapy, anesthetic drugs, interaction, adverse effects, and drug combination. Negative perioperative outcomes may be related to the chemotherapy. Regarding the type of oncological surgery, factors such as blood loss, hypothermia, and extended operative time influence the increase in morbimortality. Many anesthetic drugs are related to immunomodulation and interact with chemotherapy, which may get better or worse cancer patients. It is crucial for anesthetists to have a comprehensive understanding of the potential adverse effects of chemotherapy drugs and their interactions with anesthetics.</p>","PeriodicalId":8482,"journal":{"name":"Asian journal of anesthesiology","volume":"62 1","pages":"21-27"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Practice Algorithm of Rotational Thromboelastometry-Guided (ROTEM-Guided) Bleeding Management in Liver Transplantation. 肝脏移植术中旋转血栓弹性测量引导(ROTEM引导)出血处理实践指南。
Asian journal of anesthesiology Pub Date : 2024-12-20 Epub Date: 2024-05-01 DOI: 10.6859/aja.202403_62(1).0001
Min-Yi Tsai, Shun-Ming Chan, Nan-Kai Hung, Hou-Chuan Lai, Yao-Chia Liu, Wei-Lin Lin, Wei-Cheng Tseng, Chueng-He Lu
{"title":"Practice Algorithm of Rotational Thromboelastometry-Guided (ROTEM-Guided) Bleeding Management in Liver Transplantation.","authors":"Min-Yi Tsai, Shun-Ming Chan, Nan-Kai Hung, Hou-Chuan Lai, Yao-Chia Liu, Wei-Lin Lin, Wei-Cheng Tseng, Chueng-He Lu","doi":"10.6859/aja.202403_62(1).0001","DOIUrl":"10.6859/aja.202403_62(1).0001","url":null,"abstract":"<p><p>Liver transplantation (LT) is frequently complicated by coagulopathy associated with end-stage liver disease, which is often multifactorial and associated with hemostatic disturbances affecting both the procoagulant and anticoagulant systems. This rebalanced coagulation system may lead to bleeding diathesis or increased clot formation. Conventional coagulation tests cannot reflect these complex changes because they can only illustrate deficiencies in the procoagulant system. Viscoelastic tests such as rotational thromboelastometry (ROTEM) have been used in LT and have shown useful for detecting coagulopathy and guiding transfusions. Implementation of ROTEM-guided bleeding management algorithms has proven effectiveness in reducing bleeding, transfusion needs, complication rates, and healthcare costs in LT. This document is intended to provide a practice algorithm for the management of major bleeding and coagulopathy during LT and to encourage adaptation of the guidelines to individual institutional circumstances and resources.</p>","PeriodicalId":8482,"journal":{"name":"Asian journal of anesthesiology","volume":" ","pages":"12-20"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypovolemic Shock and Changes in Density Spectral Array of BIS During Hepatectomy. 肝切除术中的低血容量休克与 BIS 密度谱阵列的变化
Asian journal of anesthesiology Pub Date : 2024-12-20 Epub Date: 2024-08-01 DOI: 10.6859/aja.202403_62(1).0007
Tsai-Shan Wu, Zhi-Fu Wu, Hou-Chuan Lai
{"title":"Hypovolemic Shock and Changes in Density Spectral Array of BIS During Hepatectomy.","authors":"Tsai-Shan Wu, Zhi-Fu Wu, Hou-Chuan Lai","doi":"10.6859/aja.202403_62(1).0007","DOIUrl":"10.6859/aja.202403_62(1).0007","url":null,"abstract":"","PeriodicalId":8482,"journal":{"name":"Asian journal of anesthesiology","volume":" ","pages":"63-65"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Efficacy and Factors Associated With Epidural Injections in the Management of Lumbar Spinal Stenosis and in Terms of Delaying Laminectomy: A Retrospective Study. 硬膜外注射治疗腰椎管狭窄症及延迟椎板切除术的疗效及相关因素:一项回顾性研究。
Asian journal of anesthesiology Pub Date : 2024-12-20 DOI: 10.6859/aja.202403_62(1).0005
Yara Bou Sleiman, Souheil Hallit, Souheil Chamandi
{"title":"The Efficacy and Factors Associated With Epidural Injections in the Management of Lumbar Spinal Stenosis and in Terms of Delaying Laminectomy: A Retrospective Study.","authors":"Yara Bou Sleiman, Souheil Hallit, Souheil Chamandi","doi":"10.6859/aja.202403_62(1).0005","DOIUrl":"10.6859/aja.202403_62(1).0005","url":null,"abstract":"<p><strong>Background: </strong>Lumbar epidural injections have been studied as symptomatic treatments for lumbar spinal stenosis (LSS). However, results about their efficacy have been controversial, and data regarding their use is scarce. Our purpose in this article is to study the efficacy of epidural injections in the management of pain and disability in patients suffering from spinal stenosis, to study the factors which can affect their efficacy, and to discuss whether they could replace surgery or not.</p><p><strong>Methods: </strong>A retrospective study between 2021 and 2022 took place in a Pain Clinic located in Notre-Dame des Secours University Hospital-Lebanon. The study was done on 128 patients, of whom 18 were excluded because they underwent laminectomy before taking the transforaminal lumbar epidural injections. Medical records were viewed. Outcome measures were checked before and after epidural injections using the numerical pain scale and the Oswestry Disability Index (ODI) scale. Physical activity was assessed with a physical activity index.</p><p><strong>Results: </strong>Back pain scores (9.46 ± 1.07 vs. 3.91 ± 3.13; P < 0.001), leg pain scores (9.31 ± 1.41 vs. 3.75 ± 3.17; P < 0.001), and ODI scores (27.45 ± 8.97 vs. 9.40 ± 9.42; P < 0.001) decreased after the injection compared to before it. A higher physical activity index was significantly associated with a decrease in back pain, leg pain, and ODI scores after epidural injection. In 57.8% of the patients, epidural injections were sufficient for pain management without the need for surgery.</p><p><strong>Conclusion: </strong>Epidural injections are effective in the management of back and leg pain associated with LSS and in improving patients' disability. Engaging in activities like walking and swimming is associated with better results. In some cases, epidural injections may replace surgery.</p>","PeriodicalId":8482,"journal":{"name":"Asian journal of anesthesiology","volume":"62 1","pages":"39-45"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postoperative Cognitive Dysfunction: A Review. 术后认知功能障碍:综述。
Asian journal of anesthesiology Pub Date : 2024-12-20 Epub Date: 2024-08-01 DOI: 10.6859/aja.202403_62(1).0001
Neelesh Anand, Reetika Gupta, Shashi Prakash Mishra, Manjaree Mishra
{"title":"Postoperative Cognitive Dysfunction: A Review.","authors":"Neelesh Anand, Reetika Gupta, Shashi Prakash Mishra, Manjaree Mishra","doi":"10.6859/aja.202403_62(1).0001","DOIUrl":"10.6859/aja.202403_62(1).0001","url":null,"abstract":"<p><p>Elderly patients are more vulnerable to cognitive dysfunction in the postoperative period. Patients who are apparently well in cognitive functions in the preoperative period after undergoing anesthesia in noncardiac surgery will develop symptoms of cognitive dysfunction. Postoperative cognitive dysfunction (POCD) doesn't continue for a long duration and usually undergoes self-resolution. Proper definitions and congruous tests for diagnosis are absent. Rigorous preoperative assessment of cognitive function and distinguishing risk factors are indispensable for recognizing the range of POCD and its association with surgery and anesthesia. Recent studies haven't revealed any anesthesia technique or drug which can significantly reduce the incidence of POCD. Therefore, giving accurate information to patients can be challenging.</p>","PeriodicalId":8482,"journal":{"name":"Asian journal of anesthesiology","volume":" ","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Top 100 Most-Cited Articles on Difficult Airway Management From 2011 to 2022: A Bibliometric Analysis. 2011 - 2022年气道困难管理100篇被引文章的文献计量分析
Asian journal of anesthesiology Pub Date : 2024-12-20 DOI: 10.6859/aja.202403_62(1).0006
Lawrence Huang, Steven H Hsu, Yi Ting Chuang, Yu Hsuan Tang, Hsien Yung Lai
{"title":"Top 100 Most-Cited Articles on Difficult Airway Management From 2011 to 2022: A Bibliometric Analysis.","authors":"Lawrence Huang, Steven H Hsu, Yi Ting Chuang, Yu Hsuan Tang, Hsien Yung Lai","doi":"10.6859/aja.202403_62(1).0006","DOIUrl":"10.6859/aja.202403_62(1).0006","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Difficult airway management (DAM) presents a complex array of challenges inherent in establishing and maintaining a patient's airway during medical procedures or emergencies. Consequences of compromised DAM are profound, ranging from hypoxia, and aspiration, to cardiac arrest. Despite the ongoing progress and innovation in airway management, DAM remains a significant clinical challenge. Performing a bibliometric analysis of the most cited articles in this domain offers quantitative and qualitative insights into the landscape and trend of key research; our analysis revealed an increasing focus on video laryngoscopy research over the past decade, with a notable surge in studies related to airway management during infectious disease outbreaks in recent years.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We performed a bibliometric analysis of the 100 most-cited articles on DAM (Top100DAM) published between 2011 and 2022, sourced from both PubMed and Web of Science databases. Employing social network analysis, we identified key associated topics and cluster terms. Cluster terms are broad categories encompassing related topic terms. Topic terms are specific keywords or phrases found in the articles. Citation counts were estimated for each article, and cluster-specific reviews were generated using the Medical Query Expert software.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The Top100DAM comprised 53 topic terms spanning 11 cluster terms. \"Anesthesiology\" stood out as the most frequently featured cluster, and \"betacoronavirus\" had the highest Impact Factor. There was a significant correlation between the counts between the inferred citation based on cluster terms and the observed citation (Pearson's R = 0.06, P = 0.02). To visualize, the network visualization and Sankey diagrams were used to illustrate the characteristics of the articles. The generated summary, utilizing natural language processing techniques, underscored the role of fiber-optic technology and video laryngoscopy in addressing DAM. During the COVID-19 pandemic, experts recommended the provision of supplemental oxygen and the prioritization of video laryngoscopy for anticipated DAM scenarios. Notably, the most cited articles predominantly concentrated on the importance of practice driven by guidelines and protocols for clinicians and anesthesiologists to manage difficult airways effectively.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;DAM plays a central role in anesthesiology research, with a significant emphasis on guideline development, technological advancements like video laryngoscopy, and adapting practices for infectious disease scenarios. The increased publication volume and high citation rates during the COVID-19 pandemic underscore how ongoing research and innovation have accelerated, refining DAM practices. Articles with high citation rates mostly pertain to guidelines, illustrating their substantial impact on clinical practice and the necessity for studies to base their discus","PeriodicalId":8482,"journal":{"name":"Asian journal of anesthesiology","volume":"62 1","pages":"46-62"},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Propofol on Metabolic Acidosis in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass. 异丙酚对体外循环心脏手术患者代谢性酸中毒的影响。
Asian journal of anesthesiology Pub Date : 2024-12-03 DOI: 10.6859/aja.202412_62(4).0005
Vu Thanh Lam, Nguyen Minh Ly
{"title":"Effect of Propofol on Metabolic Acidosis in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass.","authors":"Vu Thanh Lam, Nguyen Minh Ly","doi":"10.6859/aja.202412_62(4).0005","DOIUrl":"10.6859/aja.202412_62(4).0005","url":null,"abstract":"<p><strong>Background: </strong>Propofol has been associated with metabolic acidosis in case reports. However, the results of studies in patients undergoing non-cardiac surgery are controversial. On the other hand, there have been no randomized controlled studies addressing this issue in patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). In this study, we investigated whether propofol was associated with metabolic acidosis in patients undergoing cardiac surgery with CPB.</p><p><strong>Methods: </strong>Forty patients undergoing cardiac surgery with CPB were randomly assigned to receive total anesthesia with propofol (intervention group) or sevoflurane (control group), respectively. Except for this, the anesthetic and surgical management was the same in all patients. The primary outcomes were the changes in arterial blood pH, base excess, HCO_3^-, and lactate levels during surgery. The secondary outcomes included serum aspartate transaminase (AST), alanine transaminase (ALT), urea, and creatinine levels, as well as the proportion of patients with increased liver enzymes and kidney damage at the end of surgery, and the proportion of patients with arrhythmia during surgery.</p><p><strong>Results: </strong>The rate of metabolic acidosis with high lactate at the end of surgery in the propofol group (intervention group) was statistically higher than that in the sevoflurane group (control group). Nevertheless, no difference in serum AST, ALT, urea, and creatinine levels between the two groups, and the proportions of patients with increased liver enzymes and kidney damage at the end of surgery, as well as the proportion of patients with arrhythmia during surgery.</p><p><strong>Conclusion: </strong>Total anesthesia with propofol was associated with metabolic acidosis but did not significantly affect increased liver enzymes, kidney damage, and arrhythmias when compared with the control group in patients undergoing cardiac surgery with CPB.</p>","PeriodicalId":8482,"journal":{"name":"Asian journal of anesthesiology","volume":"62 4","pages":"216-226"},"PeriodicalIF":0.0,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145450569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书