Arquivos brasileiros de oftalmologia最新文献_第9页

Protein profile of purified plasma- and aqueous humor-derived extracellular vesicles from patients with ocular toxoplasmosis. 来自眼弓形虫病患者的纯化血浆和眼房水源性细胞外囊泡的蛋白质谱。

IF 1.1 4区医学

Arquivos brasileiros de oftalmologia Pub Date : 2024-08-02 eCollection Date: 2024-01-01 DOI: 10.5935/0004-2749.2023-0037

Deise F Costa, Carmen Luz Pessuti, Thupten Tsering, Mohamed Abdouh, Kleber Ribeiro, Heloisa Nascimento, Alessandra G Commodaro, Julia V Burnier, Rubens Belfort, Miguel N Burnier

{"title":"Protein profile of purified plasma- and aqueous humor-derived extracellular vesicles from patients with ocular toxoplasmosis.","authors":"Deise F Costa, Carmen Luz Pessuti, Thupten Tsering, Mohamed Abdouh, Kleber Ribeiro, Heloisa Nascimento, Alessandra G Commodaro, Julia V Burnier, Rubens Belfort, Miguel N Burnier","doi":"10.5935/0004-2749.2023-0037","DOIUrl":"https://doi.org/10.5935/0004-2749.2023-0037","url":null,"abstract":"Purpose: To characterize the extracellular vesicle protein cargo in the aqueous humor and plasma of patients with ocular toxoplasmosis.Methods: Aqueous humor and plasma were collected from six patients with active ocular toxoplasmosis and six patients with cataract. Extracellular vesicles were isolated, and western blotting and mass spectrometry were performed for protein analysis.Results: All plasma samples from patients with ocular toxoplasmosis and cataract were positive for the tetraspanins CD63 and TSG101. However, the aqueous humor from patients with ocular toxoplasmosis was positive only for CD63. Sixty-seven new unreported proteins were identified in the aqueous humor and plasma of patients with the ocular toxoplasmosis and cataract. Of the 67 proteins, 10 and 7 were found only in the cataract and ocular toxoplasmosis groups, respectively. In general, these proteins were involved in immune system activation and retina homeostasis and were related to infections and retina-associated diseases.Conclusion: The distinct protein signatures between ocular toxoplasmosis and cataract may be helpful in the differential diagnosis of ocular toxoplasmosis. However, more studies are needed to better understand the role of these proteins in the pathogenesis of ocular toxoplasmosis.","PeriodicalId":8397,"journal":{"name":"Arquivos brasileiros de oftalmologia","volume":"88 1","pages":"e20230037"},"PeriodicalIF":1.1,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Meibography health score: a simple grading system for isotretinoin-induced meibography alterations on patients with acne vulgaris. 甲胎蛋白造影健康评分：异维A酸引起的寻常型痤疮患者甲胎蛋白造影改变的简单分级系统。

IF 1.1 4区医学

Arquivos brasileiros de oftalmologia Pub Date : 2024-08-02 eCollection Date: 2024-01-01 DOI: 10.5935/0004-2749.2023-0150

Fabio Mendonça Xavier Andrade, Flavio Hirai, Tais Hitomi Wakamatsu, Rebecca Ignacio Subira Medina, Denise de Freitas

{"title":"Meibography health score: a simple grading system for isotretinoin-induced meibography alterations on patients with acne vulgaris.","authors":"Fabio Mendonça Xavier Andrade, Flavio Hirai, Tais Hitomi Wakamatsu, Rebecca Ignacio Subira Medina, Denise de Freitas","doi":"10.5935/0004-2749.2023-0150","DOIUrl":"https://doi.org/10.5935/0004-2749.2023-0150","url":null,"abstract":"Purpose: To develop a simple, subjective, and reliable grading scale for isotretinoin-induced meibography changes.Methods: After analyzing meibography images obtained from systemic isotretinoin users, a grading scale was proposed and named \"meibography health score.\" The score ranged from 1 to 3, with decreasing gland reflectivity and identifiable margins. A total of 11 medical professionals were asked to grade 10 meibography images obtained from isotretinoin users using the proposed scale and were divided into three groups: (A) ophthalmologists with experience with meibography, (B) ophthalmologists with no experience with meibography, and (C) radiologists. The kappa statistic was determined to test interrater reliability.Results: The overall kappa was approximately 0.64. The kappa scores for Groups A, B, and C were 0.78, 0.59, and 0.90, respectively. Grade 2 had the lowest kappa scores (0.62, 0.35, and 0.82 for A, B, and C, respectively) and grade 3 the highest (0.78, 0.90, and 1.0 for A, B and C, respectively). Furthermore, Group C had the highest kappa scores and Group B the lowest.Conclusion: The meibography health score exhibited good interrater reliability, particularly in severe cases.","PeriodicalId":8397,"journal":{"name":"Arquivos brasileiros de oftalmologia","volume":"88 1","pages":"e20230150"},"PeriodicalIF":1.1,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Night-time blood pressure dipping, but not 24-h blood pressure level, is linked to increased 24-h ocular volume slope. 夜间血压下降（而非 24 小时血压水平）与 24 小时眼容量斜率增加有关。

IF 1.1 4区医学

Arquivos brasileiros de oftalmologia Pub Date : 2024-08-02 eCollection Date: 2024-01-01 DOI: 10.5935/0004-2749.2022-0236

Janusz Skrzypecki, F M Szymański, J Przybek-Skrzypecka, Justyna Izdebska, A Ryś-Czaporowska, K J Filipiak, Jacek P Szaflik

{"title":"Night-time blood pressure dipping, but not 24-h blood pressure level, is linked to increased 24-h ocular volume slope.","authors":"Janusz Skrzypecki, F M Szymański, J Przybek-Skrzypecka, Justyna Izdebska, A Ryś-Czaporowska, K J Filipiak, Jacek P Szaflik","doi":"10.5935/0004-2749.2022-0236","DOIUrl":"https://doi.org/10.5935/0004-2749.2022-0236","url":null,"abstract":"Purpose: This study investigated the relationship between blood pressure and intraocular pressure in treatmentnaive, non-glaucoma patients with different blood pressure statuses, focusing on the 24-h ocular volume and nocturnal blood pressure decline.Methods: Treatment-naive, non-glaucoma patients undergoing hypertension evaluation were enrolled as study participants. Simultaneous 24-h ambulatory blood pressure measurement and 24-h ocular volume recording with a contact lens sensor. We also compared ocular volume curve parameters between normotensive and hypertensive patients, as well as between those with and without nocturnal blood pressure decline.Results: A total of 21 patients, including 7 normotensive and 14 treatment-naive hypertensive individuals, were included in the study. of them, 11 were dippers and 10 were non-dippers. No significant difference in the 24-h ocular volume slope was observed between the hypertensive and normotensive patients (p=0.284). However, dippers had a significantly higher 24-h ocular volume slope (p=0.004) and nocturnal contact lens sensor output (p=0.041) than non-dippers.Conclusion: Nocturnal blood pressure decline, rather than the blood pressure level, is associated with the increased 24-h ocular volume slope and nocturnal ocular volume. Further studies are required to determine whether the acceleration of glaucoma progression in dippers is primarily due to low blood pressure, high intraocular pressure, or a combination of both.","PeriodicalId":8397,"journal":{"name":"Arquivos brasileiros de oftalmologia","volume":"88 1","pages":"e20220236"},"PeriodicalIF":1.1,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141896643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Macular perfusion changes in people administered two types of COVID-19 vaccines: comment. 两种 COVID-19 疫苗接种者的黄斑灌注变化：评论。

IF 1.1 4区医学

Arquivos brasileiros de oftalmologia Pub Date : 2024-07-15 eCollection Date: 2024-01-01 DOI: 10.5935/0004-2749.2024-0065

Hinpetch Daungsupawong, Viroj Wiwanitkit

引用次数: 0

Who should finance science? A consideration about publication costs. 谁来资助科学？关于出版费用的思考

IF 1.1 4区医学

Arquivos brasileiros de oftalmologia Pub Date : 2024-07-15 eCollection Date: 2024-01-01 DOI: 10.5935/0004-2749.2024-1010

Newton Kara-Junior

引用次数: 0

An unexpected case of a large metallic intraorbital foreign body. 一例意外的眶内大型金属异物。

IF 1.1 4区医学

Arquivos brasileiros de oftalmologia Pub Date : 2024-07-15 eCollection Date: 2024-01-01 DOI: 10.5935/0004-2749.2021-0263

Bangtao Yao, Gang Liu, Bei Wang

引用次数: 0

Segmental vitiligo of the lid margin with leukotrichia of lashes in a child. 一名儿童的睑缘节段性白癜风伴有睫毛白斑。

IF 1.1 4区医学

Arquivos brasileiros de oftalmologia Pub Date : 2024-07-15 eCollection Date: 2024-01-01 DOI: 10.5935/0004-2749.2023-0091

Janani Rajagopal

引用次数: 0

Morgagnian cataract. 莫尔加尼白内障

IF 1.1 4区医学

Arquivos brasileiros de oftalmologia Pub Date : 2024-07-15 eCollection Date: 2024-01-01 DOI: 10.5935/0004-2749.2024-0121

Fabio Marinho, Nicole B M Almeida, Newton Kara-Junior

引用次数: 0

Corneal Dellen. 角膜戴伦

IF 1.1 4区医学

Arquivos brasileiros de oftalmologia Pub Date : 2024-05-27 eCollection Date: 2024-01-01 DOI: 10.5935/0004-2749.2023-0060

Samara Barbara Marafon

引用次数: 0

Resolution of post-trauma conjunctival inclusion cyst using 0.5% timolol maleate eyedrops. 使用 0.5% 马来酸噻吗洛尔眼药水治疗外伤后结膜包涵囊肿。

IF 1.1 4区医学

Arquivos brasileiros de oftalmologia Pub Date : 2024-05-27 eCollection Date: 2024-01-01 DOI: 10.5935/0004-2749.2023-0313

Rosalia Antunes-Foschini, Lívia Feitosa Alves

引用次数: 0