Evaluation of perioperative pachymetry of thin corneas during corneal crosslinking using hypo-osmolar riboflavin and hydroxypropyl methylcellulose.

IF 1.1 4区医学 Q3 OPHTHALMOLOGY

Arquivos brasileiros de oftalmologia Pub Date : 2024-08-02 eCollection Date: 2024-01-01 DOI:10.5935/0004-2749.2023-0056

Fábio Kenji Matsumoto, Marcelo Tojar, Luciene Barbosa de Souza

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引用次数: 0

Abstract

Purpose: This study aimed to analyze variations in intraoperative corneal thickness during corneal cross-linking in patients with keratoconus and to investigate its possible correlation with presurgical maximal keratometry (Kmax) and pachymetry.

Methods: This was a prospective case series. We used a method similar to the Dresden protocol, with the application of hydroxypropyl methylcellulose 0.1% hypo-osmolar riboflavin in corneas between 330 and 400 µm after epithelium removal. Corneal thickness was measured using portable calipers before and immediately after epithelium removal, and 30 and 60 min after the procedure.

Results: The 30 patients in this study were followed up for one year. A statistically significant difference was observed in pachymetry values during the intraoperative period (p<0.0001) and an increase of 3.05 µm (95%C1: 0.56-5.54) for each diopter was seen after epithelium removal (p0.019). We found an average Kmax difference of -2.12 D between men and women (p0.013). One year after treatment, there was a statistically significant reduction in pachymetry (p<0.0001) and Kmax (p0.0170) values.

Conclusions: A significant increase in pachymetry measurements was seen during the procedure, and most patients showed a regression in Kmax and pachymetry values one year after surgery.

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使用低渗核黄素和羟丙基甲基纤维素进行角膜交联时，对薄角膜围手术期厚度的评估。

目的：本研究旨在分析角膜交联术中角膜厚度的变化，并探讨其与手术前最大角膜厚度（Kmax）和角膜厚度测量的相关性：这是一项前瞻性病例系列研究。我们采用了与德累斯顿方案类似的方法，在去除上皮后的 330 至 400 微米角膜上涂抹 0.1% 低渗透核黄素的羟丙基甲基纤维素。在角膜上皮去除前、去除后立即以及术后 30 分钟和 60 分钟，使用便携式卡尺测量角膜厚度：本研究对 30 名患者进行了为期一年的随访。结果：对 30 名患者进行了为期一年的随访。术中观察到的角膜厚度值差异具有统计学意义（p 结论：角膜上皮去除后，角膜厚度显著增加：大多数患者的 Kmax 和测深值在术后一年都有所下降。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Arquivos brasileiros de oftalmologia OPHTHALMOLOGY-

CiteScore

1.60

自引率

0.00%

发文量

200

审稿时长

6-12 weeks

期刊介绍： The ABO-ARQUIVOS BRASILEIROS DE OFTALMOLOGIA (ABO, ISSN 0004-2749 - print and ISSN 1678-2925 - (ABO, ISSN 0004-2749 - print and ISSN 1678-2925 - electronic version), the official bimonthly publication of the Brazilian Council of Ophthalmology (CBO), aims to disseminate scientific studies in Ophthalmology, Visual Science and Health public, by promoting research, improvement and updating of professionals related to the field.