Arquivos brasileiros de oftalmologia最新文献

{"title":"Iridodialysis.","authors":"Gilberto Krasilchik, Nicole Bulgarão Maricondi Almeida, Newton Kara-Junior","doi":"10.5935/0004-2749.2025-0092","DOIUrl":"https://doi.org/10.5935/0004-2749.2025-0092","url":null,"abstract":"","PeriodicalId":8397,"journal":{"name":"Arquivos brasileiros de oftalmologia","volume":"88 5","pages":"e20250092"},"PeriodicalIF":1.1,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Müller muscle conjunctival resection: Impact on Hering's law and facial symmetry in unilateral ptosis repair.","authors":"Emine Savran Elibol, Nejla Tükenmez Dikmen","doi":"10.5935/0004-2749.2024-0318","DOIUrl":"10.5935/0004-2749.2024-0318","url":null,"abstract":"<p><strong>Purpose: </strong>Ptosis is characterized by drooping of the upper eyelid, often requiring surgical intervention for functional and aesthetic purposes. Müller's muscle conjunctival resection is a commonly utilized surgical technique to correct mild to moderate ptosis. This retrospective study aimed to evaluate the impact of Hering's law on the outcomes of unilateral Müller's muscle conjunctival resection surgery, particularly eyelid and brow symmetry.</p><p><strong>Methods: </strong>Thirty patients with unilateral ptosis underwent Müller's muscle conjunctival resection. Preand postoperative assessments included ipsilateral and contralateral side margin-reflex distance and brow position, measured through digital image analysis.</p><p><strong>Results: </strong>We found significant improvements in postoperative margin-reflex distance measurements in the ipsilateral eyelid but not in the contralateral eyelid, indicating minimal influence of Hering's law. Brow position showed a statistically significant increase on the contralateral side but not on the ipsilateral side.</p><p><strong>Conclusion: </strong>Müller's muscle conjunctival resection effectively restores symmetry in eyelid height and maintains brow symmetry. This is the first study to explore bilateral eyelid and brow symmetry after unilateral Müller's muscle conjunctival resection surgery for mild to moderate ptosis. Further research should be conducted to understand the long-term effects of Müller's muscle conjunctival resection on facial aesthetics, particularly in relation to brow position.</p>","PeriodicalId":8397,"journal":{"name":"Arquivos brasileiros de oftalmologia","volume":"88 5","pages":"e20240318"},"PeriodicalIF":1.1,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the relationship between dry eye syndrome severity and corneal sensitivity.","authors":"Zeynep Akgun, Pelin Kiyat, Idris Sarikaya, Ugur Yilmaz, Ozlem Barut Selver","doi":"10.5935/0004-2749.2024-0202","DOIUrl":"https://doi.org/10.5935/0004-2749.2024-0202","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the relationship between the objective severity of dry eye disease subjective symptoms, and corneal sensitivity.</p><p><strong>Methods: </strong>The study included 62 eyes from 31 healthy volunteers and 150 eyes from 75 patients diagnosed with dry eye disease . Participants underwent the Schirmer I test, tear break-up time assessment, and corneal staining evaluation using the Oxford Scale. Subjective symptoms were assessed through the Ocular Surface Disease Index questionnaire and a modified Ocular Surface Pain Score questionnaire. Corneal sensitivity was measured in five corneal regions using a Cochet-Bonnet esthesiometer. Dry eye disease severity was graded from 1 to 5 based on the Oxford Scale. Comparative analyses were performed.</p><p><strong>Results: </strong>Schirmer I and tear break-up time values were significantly lower in the DED group, while Ocular Surface Disease Index and Ocular Surface Pain Score were significantly higher (p<0.001 for all). Corneal sensitivity in all quadrants was significantly lower in DED patients (p<0.001 for all). A strong correlation was observed between the Ocular Surface Pain Score and the Ocular Surface Disease Index (r=0.983, p<0.001). Central corneal sensitivity exhibited a moderate positive correlation with Schirmer I and tear break-up time (p<0.001, r=0.583 and 0.657, respectively) and a moderate negative correlation with Ocular Surface Disease Index and Ocular Surface Pain Score (p<0.001, r=0.625 and -0.631, respectively). Disease severity progression was associated with increased Ocular Surface Disease Index and Ocular Surface Pain Score, but no statistically significant difference was found between Grades 3 and 5. Similarly, corneal sensitivity decreased with advancing disease severity, yet no significant difference was observed between Grades 4 and 5.</p><p><strong>Conclusion: </strong>Corneal sensitivity decreases in dry eye disease and is negatively correlated with disease severity. Subjective symptoms increase with disease progression and show a positive correlation with severity. The absence of significant differences between the advanced stages suggests that neuropathic mechanisms and subbasal nerve plexus deterioration play a role in chronic and late-stage dry eye disease.</p>","PeriodicalId":8397,"journal":{"name":"Arquivos brasileiros de oftalmologia","volume":"88 5","pages":"e20240202"},"PeriodicalIF":1.1,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are cataract surgery campaigns necessary for preventing blindness in developing countries?","authors":"Newton Kara-Junior","doi":"10.5935/0004-2749.2024-1016","DOIUrl":"10.5935/0004-2749.2024-1016","url":null,"abstract":"","PeriodicalId":8397,"journal":{"name":"Arquivos brasileiros de oftalmologia","volume":"88 4","pages":"e20241016"},"PeriodicalIF":1.1,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144558851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unwanted scenario of medical journals' future: Artificial intelligence and medical writing.","authors":"Shigeki Matsubara","doi":"10.5935/0004-2749.2025-0090","DOIUrl":"https://doi.org/10.5935/0004-2749.2025-0090","url":null,"abstract":"","PeriodicalId":8397,"journal":{"name":"Arquivos brasileiros de oftalmologia","volume":"88 3","pages":"e20250090"},"PeriodicalIF":1.1,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What can we learn from the features and presentation of retinal pigment epithelium hypertrophy?","authors":"Gustavo Rosa Gameiro, Maura Abraham-Marin, Zelia Maria Correa","doi":"10.5935/0004-2749.2025-0048","DOIUrl":"https://doi.org/10.5935/0004-2749.2025-0048","url":null,"abstract":"","PeriodicalId":8397,"journal":{"name":"Arquivos brasileiros de oftalmologia","volume":"88 3","pages":"e20250048"},"PeriodicalIF":1.1,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute dacryocystitis in children with mononucleosis.","authors":"Silvana Artioli Schellini, Tammy Hentona Osaki","doi":"10.5935/0004-2749.2025-0044","DOIUrl":"https://doi.org/10.5935/0004-2749.2025-0044","url":null,"abstract":"","PeriodicalId":8397,"journal":{"name":"Arquivos brasileiros de oftalmologia","volume":"88 3","pages":"e20250044"},"PeriodicalIF":1.1,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-world safety and efficacy of Anti-VEGF treatment in Brazil.","authors":"Mario Cesar Bulla, Daniel Lavinsky","doi":"10.5935/0004-2749.2024-0277","DOIUrl":"https://doi.org/10.5935/0004-2749.2024-0277","url":null,"abstract":"<p><strong>Purpose: </strong>This retrospective study evaluated the safety and efficacy of real-world antiangiogenic therapy for ocular conditions in the private healthcare sector in southern Brazil.</p><p><strong>Methods: </strong>Medical records from patients who underwent intravitreal anti-vascular endothelial growth factor injections over the past 12 years were reviewed retrospectively. Data collection included the primary diagnoses, drugs administered, injection techniques, adverse effects, and treatment efficacy. Efficacy was assessed by comparing preand posttreatment visual acuity and central subfield thickness in eyes with followup exceeding 2 years.</p><p><strong>Results: </strong>A total of 1,024 patients, 1,310 treated eyes, and 11,377 injections were analyzed. The injections included aflibercept (6,833), ranibizumab (3,692), bevacizumab (843), and brolucizumab (9), administered either bilaterally (3,696) or unilaterally (7,681). The most common diagnoses were diabetic macular edema, exudative age-related macular degeneration, retinal vein occlusion related macular edema, and proliferative diabetic retinopathy. No endophthalmitis cases were reported. Vitritis with transient visual acuity loss occurred in two cases following aflibercept injections. One retinal detachment case was successfully treated with vitrectomy. The median number of injections per patient was 6 (IQR [interquartile range], 3-13). Among 445 eyes from 328 patients with followup over 2 years (median, 4.05 years; IQR, 2.89-6.29), there was a significant improvement in best-corrected visual acuity from 0.3 to 0.4 (Snellen) (p<0.001) and a reduction in central subfield thickness from 361 to 267 microns (p<0.001). CST comparisons included patients with age-related macular degeneration, diabetic macular edema, and retinal vein occlusion related macular edema.</p><p><strong>Conclusion: </strong>This real-world study, the largest of its kind in Brazil, confirms the safety and efficacy of antiangiogenic therapies in the southern Brazilian private healthcare system. The findings highlight a low incidence of severe adverse events and outcomes consistent with global studies, supporting the ongoing use of antiangiogenic agents as effective and well-tolerated treatments for various ocular conditions in developing countries.</p>","PeriodicalId":8397,"journal":{"name":"Arquivos brasileiros de oftalmologia","volume":"88 4","pages":"e20240277"},"PeriodicalIF":1.1,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morning glory disc anomaly and irregular optic nerve thickness: an overlooked association.","authors":"Sérgio Ferreira Alves Júnior, Luiz Fernando Teixeira, Paulo Gois Manso, Diogo Goulart Corrêa, Soraya Silveira Monteiro, José Roberto Falco Fonseca","doi":"10.5935/0004-2749.2024-0330","DOIUrl":"https://doi.org/10.5935/0004-2749.2024-0330","url":null,"abstract":"","PeriodicalId":8397,"journal":{"name":"Arquivos brasileiros de oftalmologia","volume":"88 4","pages":"e20240330"},"PeriodicalIF":1.1,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143972781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraocular lens calculation formula developed using artificial intelligence for ultrasonic biometry.","authors":"Victor Antonio Kuiava, Eliseu Luiz Kuiava, Eduardo Ottobeli Chielli, Diane Marinho Ruschel, Samara Bárbara Marafon","doi":"10.5935/0004-2749.2024-0083","DOIUrl":"https://doi.org/10.5935/0004-2749.2024-0083","url":null,"abstract":"<p><strong>Purpose: </strong>We developed an artificial intelligence program for calculating intraocular lenses and analyzed its accuracy rate via ultrasonic biometry. This endeavor is aimed at enhancing precision and efficacy in the selection of intraocular lenses, particularly in cases where optical biometry is unavailable.</p><p><strong>Methods: </strong>Data was collected from the Hospital de Clínicas de Porto Alegre, which included cases of phacoemulsification with intraocular lens implantation, in which the lens selection was based on ultrasonic biometry. The program, implemented in Python, Java, and PHP, employs the ridge regression method. Two design options were developed: a basic model, which uses only keratometry variables (K1 and K2), axial size and final target refraction in the spherical equivalent, and an advanced model, which incorporates preoperative refraction and the patient's age. The Universal Barrett II formula was used to compare both models.</p><p><strong>Results: </strong>The sample consisted of 486 eyes from 313 patients, with 350 eyes used for program training and 136 for program validation. The spherical equivalent hit rates, with a variation of ±0.5 D, were 86% and 87.5% for the basic and advanced models, respectively, with no statistically significant difference between them. With the Barret Universal II formula, the success rate was 69%, which was significantly different from the values of the two aforementioned models (p<0.0001). The system was better for medium and long eyes but worse for short eyes (<=22.00 mm).</p><p><strong>Conclusion: </strong>The developed artificial intelligence program was superior to the Barrett formula in terms of performance, in the general context and within the subgroup of patients with longer eyes. This innovation can considerably contribute to the selection of intraocular lenses, particularly in cases where optical biometry is unavailable.</p>","PeriodicalId":8397,"journal":{"name":"Arquivos brasileiros de oftalmologia","volume":"88 4","pages":"e20240083"},"PeriodicalIF":1.1,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143953374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}