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Herpes : the journal of the IHMF最新文献

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Common questions about herpes: analysis of chat-room transcripts. 关于疱疹的常见问题:聊天室记录分析。
Herpes : the journal of the IHMF Pub Date : 2009-01-01
Lisa K Gilbert, Folashade Omisore
{"title":"Common questions about herpes: analysis of chat-room transcripts.","authors":"Lisa K Gilbert,&nbsp;Folashade Omisore","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Patients diagnosed with genital herpes typically undergo a period of psychological adjustment. Although healthcare providers can play a key role in this adjustment, in several patient surveys patients have expressed dissatisfaction with the information and counselling offered by professionals. To address this gap, providers must first identify the common questions and myths that are not addressed, or are addressed inadequately. This article is that first step. Through a content analysis of herpes chat-room transcripts captured on their website from autumn 2001 to spring 2006, researchers from the American Social Health Association identified common herpes questions and myths. The 1968 chat passages were coded into 12 themes and 50 sub-themes. Frequently, visitors' questions concerned transmission, symptoms and diagnosis followed by natural history, psychosocial issues and treatment options. The results of this analysis will aid in the creation of tailored messages to address common factual questions and provide psychosocial support.</p>","PeriodicalId":83725,"journal":{"name":"Herpes : the journal of the IHMF","volume":"15 3","pages":"57-61"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28061173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment for Epstein-Barr virus-associated PTLD. eb病毒相关PTLD的治疗。
Herpes : the journal of the IHMF Pub Date : 2009-01-01
Thomas G Gross
{"title":"Treatment for Epstein-Barr virus-associated PTLD.","authors":"Thomas G Gross","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The association between Epstein-Barr virus (EBV) and post-transplant lymphoproliferative disease (PTLD) has been recognized since the early days of transplantation. The major pathogenetic defect is the insufficient EBV-specific cytotoxic T-cell control of EBV-driven B-cell proliferations. Despite this understanding, PTLD remains a significant cause of morbidity and mortality for transplant recipients. Determining the right therapy or therapies for any given patient with PTLD remains a major clinical problem. Productive areas of investigation include: identifying who will benefit from reduction of immunosuppression only; improving methods to predict those at highest risk of PTLD; developing safe and effective pre-emptive therapies; identifying who will benefit from rituximab; and developing more effective, less toxic therapies for resistant or aggressive disease. Obstacles that exist are heterogeneity of disease and patient populations, and divergent approaches to immunosuppression and therapeutic interventions. Greater collaboration is needed between infectious disease specialists, pathologists, transplant physicians and oncologists to overcome problems and develop agreed disease definitions and interventions that can be tested in large, prospective multicentre trials.</p>","PeriodicalId":83725,"journal":{"name":"Herpes : the journal of the IHMF","volume":"15 3","pages":"64-7"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28061661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genital herpes education and counselling: testing a one-page 'FAQ' intervention. 生殖器疱疹教育和咨询:测试一页的“常见问题”干预。
Herpes : the journal of the IHMF Pub Date : 2009-01-01
Lisa K Gilbert, Fred Wyand
{"title":"Genital herpes education and counselling: testing a one-page 'FAQ' intervention.","authors":"Lisa K Gilbert,&nbsp;Fred Wyand","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Approximately 17% of adults in the USA have antibodies to herpes simplex virus type 2 (HSV-2), 85-90% of whom are unaware of their infection. Diagnosed patients are more likely to detect HSV reactivation, disclose infection status to partner(s) and employ risk-reduction strategies; therefore, diagnosing more cases may reduce herpes transmission rates. Providers are reluctant to identify genital herpes because of potentially lengthy counselling visits or discomfort in dealing with patients' emotional reactions. This study tested the efficacy of a one-page frequently-asked-questions (FAQ) sheet regarding length of initial diagnostic visit, patient satisfaction with topics covered, provider's coverage of topics and resources/referrals provided to patients. Data from 147 patients and 26 providers were analysed. When pre- and post-FAQ sheet data were compared, diagnostic visit time was not substantially reduced but there were favourable trends in patient satisfaction levels on some topics, and providers covered more topics and offered more resources. This FAQ was useful in simplifying topics, providing prompts for providers and resources for patients. While this FAQ sheet appears favourable in this exploratory study, more investigation is needed to measure the degree to which patients use and understand the FAQ sheet, and find it to be a helpful tool.</p>","PeriodicalId":83725,"journal":{"name":"Herpes : the journal of the IHMF","volume":"15 3","pages":"51-6"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28061172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytomegalovirus vaccines: at last, a major step forward. 巨细胞病毒疫苗：终于向前迈出了一大步。
Herpes : the journal of the IHMF Pub Date : 2009-01-01
Mark R Schleiss
{"title":"Cytomegalovirus vaccines: at last, a major step forward.","authors":"Mark R Schleiss","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Yow and Demmler published an editorial in 1992 entitled Congenital cytomegalovirus disease--20 years is long enough. This editorial pointed out that, despite the long-standing recognition of the major public health importance of congenital human cytomegalovirus (CMV) infection, few solutions had been forthcoming. In no area has the lack of progress been more frustrating than in the realm of CMV vaccine development. Although a number of vaccine strategies have been considered, few have advanced to the stage of efficacy testing.</p>","PeriodicalId":83725,"journal":{"name":"Herpes : the journal of the IHMF","volume":"15 3","pages":"44-5"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385584/pdf/nihms185335.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28061170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seroprevalence of herpes simplex virus-2 infection among women seeking medical care for signs and symptoms of vaginitis. 单纯疱疹病毒2型感染在因阴道炎体征和症状求医的妇女中的血清患病率
Herpes : the journal of the IHMF Pub Date : 2009-01-01
Sharon E Ross, Belvia Carter, Seraphine Lambert
{"title":"Seroprevalence of herpes simplex virus-2 infection among women seeking medical care for signs and symptoms of vaginitis.","authors":"Sharon E Ross,&nbsp;Belvia Carter,&nbsp;Seraphine Lambert","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two identically designed studies were conducted to determine the prevalence of herpes simplex virus type 2 (HSV-2) infection and viral shedding among women with no known history of genital herpes or HSV-2 seropositivity, who sought care at a US-based obstetrics/gynaecology clinic because of recurrent signs and symptoms of vaginitis. Samples comprised 50 women of any race (All-Comers Sample; Study 1) and 49 black women (Black Sample; Study 2) diagnosed at the clinic visit with vaginitis on the basis of standard work-up and medical history. In the All-Comers Sample, 15 (30%) women were HSV-2 seropositive and two (4%) were positive for HSV-2 by polymerase chain reaction (PCR); these two patients were also HSV-2 seropositive. Therefore, among patients seropositive for HSV-2, two (13%) were shedding virus at the time of the clinic visit. In the Black Sample, 25 (51%) were HSV-2 seropositive and two (4%) were PCR positive for HSV-2. Factors associated with HSV-2 seropositivity included age >30 years, erythema on pelvic examination, age < or = 15 years at first intercourse and having more than four lifetime sexual partners. The high prevalence of HSV-2 infection in these samples underscores the need to test for HSV-2 infection in women consulting with signs and symptoms of vaginitis.</p>","PeriodicalId":83725,"journal":{"name":"Herpes : the journal of the IHMF","volume":"15 3","pages":"46-50"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28061171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Varicella zoster virus redux. 水痘带状疱疹病毒。
Herpes : the journal of the IHMF Pub Date : 2009-01-01
Lawrence D Gelb
{"title":"Varicella zoster virus redux.","authors":"Lawrence D Gelb","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In May 2008, the Advisory Committee on Immunization Practices (ACIP) of the Centers for Disease Control and Prevention in the USA recommended the routine administration of a live-attenuated high-potency varicella zoster vaccine to all adults over 60 years of age without specific contraindications, for the prevention and attenuation of herpes zoster (HZ). Nevertheless, many physicians still consider this vaccine to be of marginal value. This is not a reasonable conclusion. This short article reviews available data.</p>","PeriodicalId":83725,"journal":{"name":"Herpes : the journal of the IHMF","volume":"15 3","pages":"62-3"},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28061174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The importance of cytomegalovirus-specific antibodies for the prevention of fetal cytomegalovirus infection or disease. 巨细胞病毒特异性抗体对预防胎儿巨细胞病毒感染或疾病的重要性。
Herpes : the journal of the IHMF Pub Date : 2008-11-01
Stuart P Adler, Giovanni Nigro
{"title":"The importance of cytomegalovirus-specific antibodies for the prevention of fetal cytomegalovirus infection or disease.","authors":"Stuart P Adler,&nbsp;Giovanni Nigro","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Primary maternal infection with cytomegalovirus (CMV) during or just before pregnancy is responsible for nearly all congenital infections where the baby is symptomatic at birth. If primary maternal CMV infection occurs during the first or second trimester, between one-third and one-half of fetuses become infected, and between one-half and one-third of infected fetuses go on to have symptoms at birth. Experiments using a guinea-pig model of CMV infection in pregnant dames (and subsequent observational studies in humans) indicate a beneficial effect is associated with administering high-titre CMV hyperimmunoglobulin (HIg) to pregnant women with primary CMV infection. HIg appears to be effective for treating and preventing fetal CMV infection; its mechanism of action probably includes reduced placental inflammation, viral neutralization associated with high-avidity antibodies and, possibly, downregulation of cytokine-mediated cellular immune responses.</p>","PeriodicalId":83725,"journal":{"name":"Herpes : the journal of the IHMF","volume":"15 2","pages":"24-7"},"PeriodicalIF":0.0,"publicationDate":"2008-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28457550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case report and literature review: HHV-6-associated meningoencephalitis in an immunocompetent adult. 病例报告及文献回顾:免疫功能正常的成人发生hhv -6相关脑膜脑炎。
Herpes : the journal of the IHMF Pub Date : 2008-11-01
Christopher H Trabue, Karen C Bloch, James W Myers, Jonathan P Moorman
{"title":"Case report and literature review: HHV-6-associated meningoencephalitis in an immunocompetent adult.","authors":"Christopher H Trabue,&nbsp;Karen C Bloch,&nbsp;James W Myers,&nbsp;Jonathan P Moorman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Human herpesvirus type 6 (HHV-6) has been well described as an agent of meningoencephalitis in post-haematopoietic stem cell transplantation patients, but is a rare cause of meningoencephalitis in immunocompetent adults. We report an immunocompetent adult with HHV-6-associated meningoencephalitis. The patient was an elderly diabetic man who presented with fever and confusion, with cerebrospinal fluid (CSF) pleocytosis. HHV-6 DNA was amplified from CSF by polymerase chain reaction. In our review of the medical literature we examine clinical presentations, laboratory findings, neuroimaging studies, treatments and clinical outcomes in immunocompetent patients with HHV-6 meningoencephalitis.</p>","PeriodicalId":83725,"journal":{"name":"Herpes : the journal of the IHMF","volume":"15 2","pages":"33-5"},"PeriodicalIF":0.0,"publicationDate":"2008-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28457552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Summary of the 6th International Conference on HHV-6 and -7. 第六届HHV-6和-7国际会议摘要。
Herpes : the journal of the IHMF Pub Date : 2008-11-01
Anthony L Komaroff, Dharam Ablashi, Steven Jacobson
{"title":"Summary of the 6th International Conference on HHV-6 and -7.","authors":"Anthony L Komaroff,&nbsp;Dharam Ablashi,&nbsp;Steven Jacobson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This article reports on selected presentations at the 6th International Conference on Human Herpesvirus (HHV)-6 and -7, organized by the HHV-6 Foundation. The 98 presentations--which explored in some detail the biology of HHV-6, chromosomally integrated HHV-6, diagnostic testing and manifestations of HHV-6 infection in disease. Associations between HHV-6 and -7 and a wide variety of diseases were reported, and are made plausible by the remarkably broad cellular tropism of the viruses in vitro. To determine whether these associations are causal, it is imperative to improve diagnostic technologies and to expand studies of possible disease associations. It also is important to expand on recent encouraging work identifying effective in vitro treatments for both HHV-6 and -7.</p>","PeriodicalId":83725,"journal":{"name":"Herpes : the journal of the IHMF","volume":"15 2","pages":"36-8"},"PeriodicalIF":0.0,"publicationDate":"2008-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28459761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Provocation and progress. 挑衅和进步。
Herpes : the journal of the IHMF Pub Date : 2008-11-01
Robert F Pass
{"title":"Provocation and progress.","authors":"Robert F Pass","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":83725,"journal":{"name":"Herpes : the journal of the IHMF","volume":"15 2","pages":"23"},"PeriodicalIF":0.0,"publicationDate":"2008-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28457549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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