Archives of Women's Mental Health最新文献

{"title":"Correction to: Perinatal mental health issues in consultations regarding medication use during breastfeeding: Insights from the Japan Drug Information Institute in Pregnancy (JDIIP)","authors":"Sachi Koinuma, Yasuha Ogawa, Chie Kohno, Izumi Fujioka, Mikako Goto, Koushi Yamaguchi","doi":"10.1007/s00737-026-01747-6","DOIUrl":"10.1007/s00737-026-01747-6","url":null,"abstract":"","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"29 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13447319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148676929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The efficacy of antidepressant medication versus interpersonal psychotherapy for depression in middle-aged women: a systematic review and individual participant data meta-analysis","authors":"Sanne N.E. van Haaren,&nbsp;Zachary D. Cohen,&nbsp;Jasmijn Breunese,&nbsp;Frederik J. Wienicke,&nbsp;John C. Markowitz,&nbsp;Erica S. Weitz,&nbsp;Steven D. Hollon,&nbsp;Dillon T. Browne,&nbsp;Paula Rucci,&nbsp;Carolina Corda,&nbsp;Marco Menchetti,&nbsp;Myrna M. Weissman,&nbsp;R. Michael Bagby,&nbsp;Lena C. Quilty,&nbsp;Marc B.J. Blom,&nbsp;Mario Altamura,&nbsp;Ingo Zobel,&nbsp;Elisabeth Schramm,&nbsp;Carlos Gois,&nbsp;Jos W.R. Twisk,&nbsp;Pim Cuijpers,&nbsp;Ellen Driessen","doi":"10.1007/s00737-026-01730-1","DOIUrl":"10.1007/s00737-026-01730-1","url":null,"abstract":"<div><h3>Purpose </h3><p>Depression is highly prevalent in middle-aged women (MAW), but head-to-head comparisons of first-line interventions in this population are scarce. This systematic review and individual participant data (IPD) meta-analysis examined the comparative efficacy of antidepressant medication (ADM) and interpersonal psychotherapy (IPT) for MAW (aged 40–64) versus other adults (men and non-MAW) on depression, quality of life, and interpersonal problem measures.</p><h3>Methods </h3><p>PubMed, PsycINFO, Embase, and the Cochrane Library were searched January 1, 2025 to identify randomized trials comparing ADM and IPT for adults with depression. IPD were requested and analyzed using mixed-effects models.</p><h3>Results</h3><p>IPD were obtained from 9 of the 15 (60%) identified studies, comprising 1,490 participants (527 MAW, 963 other adults). MAW status did not significantly moderate ADM versus IPT comparative efficacy on depression (<i>p</i> = .10) and interpersonal problems (<i>p</i> = .29) outcomes. The two treatments did not significantly differ in treatment effect in the MAW group (depression: <i>b</i> = -0.03, <i>p</i> = .76; interpersonal problems: <i>b</i> = -0.20, <i>p</i> = .31). MAW status significantly moderated comparative efficacy on quality of life measures (<i>b </i>= 0.37, <i>p</i> = .02). Whereas IPT was non-significantly more efficacious than ADM for MAW (<i>b</i> = -0.18, <i>p</i> = .15), ADM were non-significantly more efficacious than IPT for other adults (<i>b</i> = 0.19, <i>p</i> = .051).</p><h3>Conclusion</h3><p>This is the first IPD meta-analysis directly comparing depression treatments in MAW. The absence of treatment effect differences indicates that other factors (e.g., patient preference) may guide choice between IPT and ADM in this population.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"29 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13384990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148519675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trajectory and predictors of maternal relationship satisfaction from pregnancy to five years postpartum","authors":"Meagan E Crowther,&nbsp;Sienna Cherry O. W Starkie,&nbsp;Donna M. Pinnington,&nbsp;Sean P. A Drummond,&nbsp;Bei Bei","doi":"10.1007/s00737-026-01746-7","DOIUrl":"10.1007/s00737-026-01746-7","url":null,"abstract":"<div><h3>Purpose</h3><p>Relationship satisfaction is a key factor in women’s mental health and wellbeing outcomes, however, relationship satisfaction may change in times of stress and uncertainty, such as the perinatal period. While positive romantic relationships during the perinatal period may offer benefits, changes in relationship satisfaction and what may contribute to them longitudinally is not currently well understood.</p><h3>Method</h3><p>One hundred and fifty-seven women in late pregnancy (~ 30 weeks gestation) took part in a longitudinal analysis of relationship satisfaction from pregnancy to five years postpartum, across eight timepoints. The study is a secondary analysis of a randomised controlled trial of sleep and diet intervention. Latent growth modelling was used to examine the trajectory of relationship satisfaction change over time and explore predictors of this trajectory.</p><h3>Results</h3><p>There was a significant decline in relationship satisfaction both during pregnancy and the postpartum. Being of non-White race was associated with overall lower relationship satisfaction (<i>p</i> = 0.004). While being less financially comfortable (<i>p</i> = 0.007), having less than a postgraduate degree (<i>p</i> = 0.049), and older age (<i>p</i> = 0.026) were associated with steeper decrease in relationship satisfaction during the postpartum.</p><h3>Conclusion</h3><p>This study demonstrates that relationship satisfaction declines from pregnancy to five years postpartum in a sample of Australian mothers. Minority race, financial comfortability, education level and age may influence the magnitude of this trajectory. These findings highlight a need to better support couples during this challenging time, not just through pregnancy and birth, but also through early childhood.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"29 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-026-01746-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148466151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postpartum-onset PTSD: a DSM-6 nosologic priority","authors":"Sharon Dekel","doi":"10.1007/s00737-026-01735-w","DOIUrl":"10.1007/s00737-026-01735-w","url":null,"abstract":"<div><p>Childbirth-related PTSD is a population-level postpartum mental health concern that remains under-recognized due to limited routine PTSD screening and symptom overlap with postpartum depression and anxiety. The condition is associated with impaired mother–infant bonding and is supported by converging biological evidence consistent with PTSD in other trauma-exposed populations. We propose that DSM-6 add a PTSD timing specifier, “with postpartum onset”, defined as the onset of PTSD symptoms within 4 weeks after delivery following a childbirth event that satisfies DSM Criterion A. A full PTSD diagnosis would still require that symptoms persist for more than 1 month, as required by DSM criteria. This targeted update could improve recognition, coding, screening pathways, and research harmonization for childbirth-related PTSD.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"29 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148466319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of the eco-reproductive concern scale","authors":"Çiçek Ediz,&nbsp;Seda Er,&nbsp;Güzel Nur Yıldız,&nbsp;Derya Yanık","doi":"10.1007/s00737-026-01744-9","DOIUrl":"10.1007/s00737-026-01744-9","url":null,"abstract":"<div><h3>Purpose</h3><p>Climate change has emerged as a growing psychosocial stressor that shapes individuals’ perceptions of the future, including decisions related to childbearing. However, the lack of standardized measurement tools limits the systematic assessment of eco-reproductive concerns within public health and nursing research. This study aims to develop a measurement tool that assesses individuals’ reproductive concerns and intentions in the context of climate change and environmental crises.</p><h3>Method</h3><p>This cross-sectional methodological study was conducted with 617 adults aged 18–45 years between September and December 2025. Data were collected using the Personal Information Form and the Eco-Reproductive Concern Scale (ERCS). Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were performed on independent samples. Reliability was assessed using Cronbach’s alpha, McDonald’s omega, and split-half methods. Convergent, discriminant, and construct validity, as well as measurement invariance across gender, were evaluated. Data analyses were conducted using SPSS Statistics 29 and AMOS.</p><h3>Results</h3><p>Participants’ mean age was 26.37 ± 8.28 years in the EFA phase (74.3% women, 25.7% men) and 26.97 ± 8.65 years in the CFA phase (72.1% women, 27.9% men). EFA yielded a 28-item, four-factor structure, accounting for 70.12% of the total variance. CFA confirmed the factor structure, demonstrating acceptable model fit (χ²/df = 2.35, CFI = 0.909, TLI = 0.900, RMSEA = 0.074, SRMR = 0.064). Convergent and discriminant validity were supported by AVE, CR, and Fornell–Larcker criteria. The scale’s internal consistency was excellent (Cronbach’s α = 0.946). Measurement invariance across women and men was established at configural, metric, and scalar levels.</p><h3>Conclusions</h3><p>The study found that the ERCS is a valid and reliable instrument for assessing reproductive concerns associated with climate change. The ERCS can be used across a broad range of health research and clinical settings, including public health, nursing, medicine, psychology, and other behavioral and allied health disciplines, to better understand how environmental crises influence reproductive attitudes and intentions.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"29 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148418276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wearable-measured heart rate variability and premenstrual disorder symptoms across menstrual cycle","authors":"Qing Pan,&nbsp;Jing Zhou,&nbsp;Min Chen,&nbsp;Peijie Zhang,&nbsp;Xinyi Shi,&nbsp;Yifei Lin,&nbsp;Jin Huang,&nbsp;Yuchen Li,&nbsp;Donghao Lu","doi":"10.1007/s00737-026-01740-z","DOIUrl":"10.1007/s00737-026-01740-z","url":null,"abstract":"<div><h3>Background</h3><p>Screening premenstrual disorders (PMDs) is time-consuming and challenging, resulting in delays in detection and treatment. To characterize the temporal dynamics of portable digital-marker across the menstrual cycle and its biological basis in PMDs, we investigated the menstrual fluctuation of wearable device-based real-time heart rate variability (HRV) through menstrual cycles and its associations with premenstrual disorders (PMDs) symptoms.</p><h3>Methods</h3><p>A prospective study of female participants nested from the Care of Premenstrual Emotion Cohort was conducted. Daily HRV metrics were collected by the Huawei Fitness Tracker over 1–2 menstrual cycles. PMDs symptoms were assessed with the Daily Record of Severity of Problems on a daily basis. HRV variability across cycles was described using descriptive statistics and splines, while associations between HRV metrics and PMDs symptoms were estimated using a mixed-effect model.</p><h3>Results</h3><p>In total, 193 participants (with 68 prospectively confirmed PMDs) were included, with measures from 293 menstrual cycles. In both women with and without PMDs, SDNN, rMSSD, and HF decreased before menses and increased afterwards; the increase trends were more pronounced in women without PMDs. During the week before or after menses, levels of these HRV metrics were inversely associated with PMDs symptoms among women with PMDs (e.g., rMSSD, postmenstrual week, β = -0·036 per SD, 95% CI: -0·065 to -0·048), whereas null association was noted for those without PMDs (β = -0·001, 95% CI -0·011 to 0·009; <i>P</i>-for-difference &lt; 0·001).</p><h3>Conclusions</h3><p>Wearable device-estimated HRV fluctuate across menstrual cycles, with varying strengths of association with PMDs symptoms between individuals with and without PMDs, which may facilitate the development of digital biomarkers for future PMDs diagnostics.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"29 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-026-01740-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148395532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perinatal mental health issues in consultations regarding medication use during breastfeeding: Insights from the Japan Drug Information Institute in Pregnancy (JDIIP)","authors":"Sachi Koinuma,&nbsp;Yasuha Ogawa,&nbsp;Chie Kohno,&nbsp;Izumi Fujioka,&nbsp;Mikako Goto,&nbsp;Koushi Yamaguchi","doi":"10.1007/s00737-026-01743-w","DOIUrl":"10.1007/s00737-026-01743-w","url":null,"abstract":"<div><h3>Purpose</h3><p>We comprehensively identified the challenges associated with psychotropic-medication use during breastfeeding in Japan and explored strategies to enhance breastfeeding support.</p><h3>Methods</h3><p>We analyzed breastfeeding-consultation records of cases involving postpartum mothers received by the Japan Drug Information Institute in Pregnancy (JDIIP) between February 2012 and March 2022, and corresponding questionnaire responses regarding the use of psychotropic medications. The “Perinatal Mental Health Consensus Guide” was used as a benchmark to examine temporal trends. To assess changes in consultation patterns over time, the study period was divided into a pre-publication (2012–2016) and post-publication phase (2017–2022).</p><h3>Results</h3><p>7,863 breastfeeding consultations were analyzed. Before and after the guide’s publication, no significant difference was observed in the proportion related to mental disorders. Among consultations involving mental disorders, psychiatrists were the most common healthcare providers from whom advice had been sought before consultation, before and after the guide's publication, followed by obstetricians. Although approximately half of the healthcare providers had previously indicated that medication use during breastfeeding was possible, the proportion advising mothers to discontinue breastfeeding while taking psychotropic medications decreased after the guide’s publication. Most mothers were prescribed multiple medications, with benzodiazepines being the most frequently discussed. However, the proportion of such consultations decreased significantly after the guide’s publication.</p><h3>Conclusions</h3><p>Consultations with specialized counseling agencies regarding psychotropic medication use during breastfeeding occurred at a consistent frequency regardless of guideline dissemination. While the guidelines’ publication appears to have influenced healthcare providers' awareness, further examination is necessary to determine how best to provide information supporting breastfeeding.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"29 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-026-01743-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148389746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental health after unintended pregnancy: insights from a context with available abortion care","authors":"Wieke Y Beumer,&nbsp;Tessa J Roseboom,&nbsp;Jenneke van Ditzhuijzen","doi":"10.1007/s00737-026-01745-8","DOIUrl":"10.1007/s00737-026-01745-8","url":null,"abstract":"<div><h3>Purpose</h3><p>To investigate how unintended pregnancy (UP) is associated with the occurrence of mental health (MH) problems one year later among womxn, while also considering pregnancy outcome (abortion/continuation), co-occurring risks and protective factors. We examine this in the Dutch context, given available abortion care up to 24 weeks gestation and high diversity in people’s pregnancy intentions. We hypothesized that MH problems are more prevalent among those whose pregnancy was more unintended.</p><h3>Methods</h3><p>Data from the Dutch BluePrInt study included both womxn who had an abortion (AB, <i>n</i> = 152) and who continued their UP (CT, <i>n</i> = 212). They filled out an online survey shortly after their abortion (AB) or around 14 weeks gestation (CT), and at follow-up one year later. Key variables included pregnancy intendedness (continuously measured), anxiety/depression symptoms (measured with a screening tool based on the CIDI), social- and partner support, abuse experiences, UP-related variables (difficulty deciding, uncertainty, pressure, and negative emotions) and socioeconomic position.</p><h3>Results</h3><p>26.5% developed MH symptoms one year after their UP, with no significant differences between AB and CT groups. Pregnancy intendedness and -outcome (abortion vs. continuation), as well as their interaction, were not related to MH symptoms one year later. Previous MH was the strongest predictor of MH risks (OR: 3.54), while perceived social support from family/friends was associated with a lower risk (OR: 0.66).</p><h3>Conclusions</h3><p>In a context where abortion care is available, pregnancy intendedness and -outcome do not increase people’s risks of MH symptoms one year after experiencing an UP. Instead, previous MH and support from family/friends are important for MH after experiencing an UP. Positioning UP as inherently problematic is not warranted. Policy and practice should center people’s lived reproductive experiences and care needs.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"29 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-026-01745-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148380197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The evidence base of interventions to treat antenatal depression: a meta-analysis of randomized controlled trials","authors":"Riddhi Laijawala,&nbsp;Kristi Priestley,&nbsp;Rebecca Bind,&nbsp;Katie Hazelgrove,&nbsp;Lavinia Rebecchini,&nbsp;Madeline Kirkpatrick,&nbsp;Francesca Mancino,&nbsp;Samrina Sangha,&nbsp;Alessandra Biaggi,&nbsp;Malvika Godara,&nbsp;Claudia Buss,&nbsp;Sonja Entringer,&nbsp;Anthony Woods,&nbsp;Paola Dazzan,&nbsp;Annamaria Cattaneo,&nbsp;Carmine M Pariante","doi":"10.1007/s00737-026-01723-0","DOIUrl":"10.1007/s00737-026-01723-0","url":null,"abstract":"<div><h3>Purpose</h3><p>Antenatal depression (AD) is a mental health condition estimated to affect close to 30% of pregnant people globally. The importance of treating depression in pregnancy is underscored by its downstream impact on both maternal and infant biopsychosocial outcomes, such as preterm birth, low birthweight, and postnatal depression. Despite these outcomes, only 20% of women experiencing AD receive appropriate and timely support and treatment. This meta-analysis is a comprehensive synthesis of RCTs evaluating psychological and non-psychological interventions to treat antenatal depression, conducted as part of the HappyMums project.</p><h3>Methods</h3><p>Studies were sourced from PubMed, Embase Medline and MIDIRS (via OVID), and were included if they were (a) randomized controlled trials, (b) with pregnant people with, or at risk for depression, (c) consisted of an intervention, and (d) published in English. To estimate efficacy, Standardized Mean Differences (SMDS) were calculated with 95% confidence intervals using the post- intervention Ms and SDs of both the intervention and control groups. The I² statistic was used as an indicator of variation between studies. Analyses were conducted using the software R Studio.</p><h3>Results</h3><p>In total, 115 studies were included in the analysis. The pooled effect size of all interventions, compared with all pooled control arms, showed a clear therapeutic effect (SMD = 0.65, 95% CI 0.48; 0.83), although the between-study heterogeneity variance was high (τ² = 0.78, 95% CI 0.7;1.3). After accounting for outliers, the pooled effect size across 94 treatment arms was still SMD = 0.5 (95% CI, 0.42, 0.56). No significant subgroup differences were found by intervention type and format, or measure used.</p><h3>Conclusion</h3><p>There are numerous interventions that, on average, are moderately effective in reducing depressive symptomology in pregnancy. Future research should be aimed at addressing how to personalise the choice of treatment and improve treatment outcomes for the individual pregnant person.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"29 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-026-01723-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attention-deficit/hyperactivity disorder and snuff use prior to and early in pregnancy","authors":"Anneli Andersson,&nbsp;Sofi Oskarsson,&nbsp;Ralf-Kuja Halkola,&nbsp;Zheng Chang,&nbsp;Brian D’Onofrio,&nbsp;Henrik Larsson,&nbsp;Catherine Tuvblad","doi":"10.1007/s00737-026-01742-x","DOIUrl":"10.1007/s00737-026-01742-x","url":null,"abstract":"<div><h3>Background</h3><p>ADHD is a neurodevelopmental disorder linked to impulsivity and self-regulation difficulties. While the association between ADHD and nicotine dependence is well-established, less is known about the association with smokeless tobacco use, such as snuff. Given the adverse health effects of nicotine during pregnancy, this study examines whether women diagnosed with ADHD are more likely to use snuff prior to and early in pregnancy, and whether they persist in use between these periods. This study also explores the associations between ADHD and snuff use in the presence of common psychiatric disorders: depression, anxiety and substance use disorders (SUDs).</p><h3>Methods</h3><p>Using Swedish population-based registers, we identified women who gave birth between 2000 and 2020. ADHD was defined based on clinical diagnoses and/or ADHD medication prescriptions. Snuff use was self-reported during a prenatal care visit. Logistic regression models estimated odds ratios (ORs) with 95% confidence intervals (CIs) for snuff use prior to and early in pregnancy among women with ADHD, adjusting for sociodemographic factors. We also stratified the analyses by depression, anxiety, and/or SUDs to assess potential differences in associations.</p><h3>Results</h3><p>Women diagnosed with ADHD were more likely to use snuff prior to pregnancy (adjOR = 1.89, 95% CI: 1.83–1.95), early in pregnancy (adjOR = 2.43, 95% CI: 2.32–2.55), as well as be persistent snuff users (adjOR = 2.39, 95% CI: 2.27–2.52) compared to women without ADHD. Stratification by common psychiatric disorders revealed that the associations between ADHD and snuff use prior to and early in pregnancy were strongest among women diagnosed with ADHD without depression, anxiety, and/or SUDs.</p><h3>Conclusions</h3><p>ADHD is an important risk factor for snuff use prior to and early in pregnancy, underscoring the need for targeted interventions to prevent nicotine use in young women with ADHD as part of integrated care.</p><h3>Trial registration</h3><p>Retrospectively registered.</p></div>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":"29 4","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00737-026-01742-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148359219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}