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Suicidal Thoughts and Behaviors in Parents Caring for Children with Disabilities and Long-Term Illnesses. 照顾残疾儿童和长期患病儿童的父母的自杀想法和行为。
IF 2.5 3区 医学
Archives of Suicide Research Pub Date : 2025-04-01 Epub Date: 2024-07-01 DOI: 10.1080/13811118.2024.2363230
Siobhan T O'Dwyer, Anna Sansom, Becky Mars, Lisa Reakes, Charmaine Andrewartha, Julia Melluish, Anna Walker, Lucy Biddle, Tom Slater, Dan Burrows, Richard P Hastings, Paul Moran, Paul Stallard, Astrid Janssens
{"title":"Suicidal Thoughts and Behaviors in Parents Caring for Children with Disabilities and Long-Term Illnesses.","authors":"Siobhan T O'Dwyer, Anna Sansom, Becky Mars, Lisa Reakes, Charmaine Andrewartha, Julia Melluish, Anna Walker, Lucy Biddle, Tom Slater, Dan Burrows, Richard P Hastings, Paul Moran, Paul Stallard, Astrid Janssens","doi":"10.1080/13811118.2024.2363230","DOIUrl":"10.1080/13811118.2024.2363230","url":null,"abstract":"<p><strong>Objective: </strong>There is a growing body of evidence on suicide risk in family carers, but minimal research on parents caring for children with disabilities and long-term illnesses. The aim of this study was to conduct the first dedicated research on suicide risk in parent carers and identify: (1) the number of parent carers experiencing suicidal thoughts and behaviors, and (2) the risk and protective factors for suicidality in this population.</p><p><strong>Method: </strong>A cross-sectional survey of parent carers in England (<i>n</i> = 750), co-produced with parent carers. Suicidal thoughts and behaviors were measured with questions from the Adult Psychiatric Morbidity Survey. Frequencies summarized the proportion of carers experiencing suicidal thoughts and behaviors. Logistic regressions identified risk and protective factors.</p><p><strong>Results: </strong>42% of parents had experienced suicidal thoughts and behaviors while caring for a disabled or chronically ill child. Only half had sought help for these experiences. Depression, entrapment, dysfunctional coping, and having a mental health diagnosis prior to caring, were significant risk factors.</p><p><strong>Conclusion: </strong>Parent carers contemplate suicide at levels that exceed those of other family carers and the general public. There is an urgent need, in policy and practice, to recognize parent carers as a priority group for prevention and intervention.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"468-485"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141465858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Suicides, Other External Causes of Death, and Psychiatric Status in Suicide Attempters: A National Registry-Based Analysis in Israel, 2006-2020. 自杀、其他外部死因和自杀企图者的精神状况:2006-2020 年以色列全国登记分析》。
IF 2.5 3区 医学
Archives of Suicide Research Pub Date : 2025-04-01 Epub Date: 2024-07-13 DOI: 10.1080/13811118.2024.2372609
Gad Lubin, Ziona Haklai, Nehama Goldberger
{"title":"Suicides, Other External Causes of Death, and Psychiatric Status in Suicide Attempters: A National Registry-Based Analysis in Israel, 2006-2020.","authors":"Gad Lubin, Ziona Haklai, Nehama Goldberger","doi":"10.1080/13811118.2024.2372609","DOIUrl":"10.1080/13811118.2024.2372609","url":null,"abstract":"<p><strong>Objective: </strong>To assess risk factors and rates of suicide and other external cause deaths, among suicide attempters compared to the total population, stratified by psychiatric hospitalization discharge and mental diagnosis.</p><p><strong>Methods: </strong>A national registry-based analysis of suicide and external cause mortality was performed among suicide attempters between 2006 and 2020 in Israel in the National Hospital ED database. Data was stratified by psychiatric hospitalization status by linking to the national psychiatric case registry. Age adjusted mortality rates were calculated.A multivariate cox regression model assessed the relative risk of demographic factors and psychiatric diagnosis and hospitalization on outcomes.</p><p><strong>Results: </strong>Among 57,579 first suicide attempters, of whom 16,874 had a psychiatric hospitalization, there were 853 suicides (1.5%) and 473 deaths from other external causes (0.8%), 485 suicides (2.9%) and 199 external cause deaths (1.2%) in the psychiatric group. Suicide risk was highest in the year after the attempt, but continued throughout the study, particularly in the psychiatric hospitalized group. Suicide rates within one year of first suicide attempt were 137 (95% CI 122-152) times higher than the total population, 190 (155-233) times in females and 128 (112-145) times in males, 178 (153-207), 243 (181-325) and 158 (132-190) times higher, respectively, in those with a psychiatric hospitalization.</p><p><strong>Conclusions: </strong>We found a greatly increased risk for suicide and significant increase for other external causes of death amongst a cohort of suicide attempters, compared to the total population, particularly those with a history of psychiatric hospitalization.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"512-526"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141603239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reliability of Suicide Risk Estimates: A Vignette Study. 自杀风险估计的可靠性:小故事研究
IF 2.5 3区 医学
Archives of Suicide Research Pub Date : 2025-04-01 Epub Date: 2024-07-24 DOI: 10.1080/13811118.2024.2382709
Finn Dario Kolochowski, Nina Kreckeler, Thomas Forkmann, Tobias Teismann
{"title":"Reliability of Suicide Risk Estimates: A Vignette Study.","authors":"Finn Dario Kolochowski, Nina Kreckeler, Thomas Forkmann, Tobias Teismann","doi":"10.1080/13811118.2024.2382709","DOIUrl":"10.1080/13811118.2024.2382709","url":null,"abstract":"<p><strong>Objective: </strong>Suicide risk assessments are obligatory when patients express a death wish in clinical practice. Yet, suicide risk estimates based on unguided risk assessments have been shown to be of low reliability. Since generalizability of previous studies is limited, the current study aimed to assess inter-rater and intra-rater reliability of risk estimates conducted by psychotherapists and psychology students using written case vignettes.</p><p><strong>Method: </strong>In total, <i>N</i> = 256 participants (psychology students, psychotherapists) were presented with 24 case vignettes describing patients at either low, moderate, severe or extreme risk of suicide. Participants were asked to assign a level of risk to each single vignette at a baseline assessment and again at a follow-up assessment two weeks later.</p><p><strong>Results: </strong>Risk estimates showed a low inter-rater reliability, both for students (AC<sub>1</sub> = .35) and for psychotherapists (AC<sub>1</sub> = .44). Intra-rater reliability was moderate for psychotherapists (AC<sub>1</sub> = .59) and rather low for psychology students (AC<sub>1</sub> = .47). In general, intra- and intra-rater reliability were highest for vignettes displaying \"low\" and \"extreme\" risk.</p><p><strong>Conclusions: </strong>The results highlight that the reliability of unguided suicide risk assessments is questionable. Standardized risk assessment protocols are therefore recommended. Nonetheless, even reliable risk estimation does not imply predictive validity of risk estimates for future suicidal behavior.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"544-555"},"PeriodicalIF":2.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141750939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interpersonal Sensitivity and Social Problem-Solving in Adolescents with Suicide Attempts or Non-suicidal Self-Injury. 有自杀或非自杀自伤倾向青少年的人际敏感性与社会问题解决。
IF 2.5 3区 医学
Archives of Suicide Research Pub Date : 2025-03-18 DOI: 10.1080/13811118.2025.2476987
Julianne G Wilner, Emma Cho, Alessandro S De Nadai, Josephine S Au, Jillian M Russo, Courtney Kaplan, Maria Naclerio, Eileen Lee, Angela Salisbury, Daniel P Dickstein
{"title":"Interpersonal Sensitivity and Social Problem-Solving in Adolescents with Suicide Attempts or Non-suicidal Self-Injury.","authors":"Julianne G Wilner, Emma Cho, Alessandro S De Nadai, Josephine S Au, Jillian M Russo, Courtney Kaplan, Maria Naclerio, Eileen Lee, Angela Salisbury, Daniel P Dickstein","doi":"10.1080/13811118.2025.2476987","DOIUrl":"https://doi.org/10.1080/13811118.2025.2476987","url":null,"abstract":"<p><strong>Objective: </strong>Interpersonal dysfunction robustly predicts suicide attempts (SA) and non-suicidal self-injury (NSSI) in adolescents. We sought to better elucidate how two interpersonal constructions (interpersonal sensitivity and social problem-solving strategies) may lead to NSSI <i>vs.</i> SA in adolescents.</p><p><strong>Method: </strong>We compared non-overlapping groups of adolescents engaged in either SA (<i>n</i> = 49, <i>M</i><sub>age</sub> = 15.80, <i>SD</i> = 1.23, 63% female) or NSSI (<i>n</i> = 50, <i>M</i><sub>age</sub> = 15.35, <i>SD</i> = 1.34, 82% female), and healthy controls (HC; <i>n</i> = 43, <i>M</i><sub>age</sub> = 15.46, <i>SD</i> = 1.30, 61% female). We hypothesized: (1) greater interpersonal sensitivity and deficits in social problem-solving strategies would differentiate the three groups and indicate higher risk for being in the NSSI and SA groups, relative to the HC groups, and (2) amongst clinical groups, there would be greater deficits in social problem-solving in the SA group, and greater interpersonal sensitivity in the NSSI group.</p><p><strong>Results: </strong>NSSI and SA groups demonstrated more interpersonal sensitivity and lower (i.e., worse) social problem-solving skills <i>vs.</i> HCs. Participants were more likely to be in both the SA and NSSI groups based on interpersonal sensitivity (OR<sub>SA</sub> = 2.61; OR<sub>NSSI</sub> = 2.75) and social problem-solving (OR<sub>SA</sub> = 19.11; OR<sub>NSSI</sub> = 10.89). Significant differences were observed between the NSSI and SA groups on interpersonal sensitivity [<i>t</i>(97) = 4.28, <i>p</i> < .001, <i>d</i> = 0.86; higher levels in the NSSI group], but not on social problem-solving [<i>t</i>(97) = 1.97, <i>p</i> = .052, <i>d</i> = 0.40].</p><p><strong>Conclusions: </strong>Both greater interpersonal sensitivity and challenges in social problem-solving predict NSSI and suicidal behavior in adolescents, and interpersonal sensitivity may be a particularly salient risk factor for NSSI. Implications for treatment and future research are discussed.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"1-16"},"PeriodicalIF":2.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do Positive Gatekeeper Training Outcomes Predict Gatekeeper Intervention Behaviours? 积极的守门人培训结果能预测守门人的干预行为吗?
IF 2.5 3区 医学
Archives of Suicide Research Pub Date : 2025-02-23 DOI: 10.1080/13811118.2025.2469882
Glenn Holmes, Amanda Clacy, Anita Hamilton, Kairi Kõlves
{"title":"Do Positive Gatekeeper Training Outcomes Predict Gatekeeper Intervention Behaviours?","authors":"Glenn Holmes, Amanda Clacy, Anita Hamilton, Kairi Kõlves","doi":"10.1080/13811118.2025.2469882","DOIUrl":"https://doi.org/10.1080/13811118.2025.2469882","url":null,"abstract":"<p><strong>Objective: </strong>Evidence for Gatekeeper Training (GKT) has shown that training outcomes are generally maintained at follow-up. Research on how improvements in GKT outcomes translate to intervention behavior is inconclusive, and some studies show that despite significant positive effects on GKT outcomes, there is no effect on GK behaviors.</p><p><strong>Method: </strong>A non-experimental pre-post and follow-up survey design was used with a sample of 60 participants who voluntarily completed one of 12 half-day (4-hour) GKT sessions. Path Analysis was applied to pre- and post-intervention training outcomes, and a third model assessed the behavioral effect of the change in participant scores from pre- to post.</p><p><strong>Results: </strong>Suicide prevention knowledge retained by participants at 6-months after GKT was predictive of increased GK behavior in the 6-months following GKT. Knowledge at follow-up was the only significant predictor of behavior (<i>p</i> < .05), no other regression pathways were significant.</p><p><strong>Conclusions: </strong>Gatekeeper preparedness, efficacy, and reluctance outcomes were not predictive of GK behavior. The findings of this study represent a lack of understanding regarding how the specific aims of GKT are translated into intervention behavior to identify, intervene, support, and refer potentially at-risk individuals.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"1-14"},"PeriodicalIF":2.5,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and Association of Suicidal Ideation and High Risk Drinking in Men and Women: Results from a Representative German Household Survey. 自杀意念和高危饮酒在男性和女性中的流行程度及其关联:来自一项有代表性的德国家庭调查的结果。
IF 2.5 3区 医学
Archives of Suicide Research Pub Date : 2025-02-21 DOI: 10.1080/13811118.2025.2464061
Jim Schmeckenbecher, Nestor D Kapusta, Christina Alma Emilian, Elmar Brähler, Victor Blüml, Jürgen Fuchshuber, Mareike Ernst
{"title":"Prevalence and Association of Suicidal Ideation and High Risk Drinking in Men and Women: Results from a Representative German Household Survey.","authors":"Jim Schmeckenbecher, Nestor D Kapusta, Christina Alma Emilian, Elmar Brähler, Victor Blüml, Jürgen Fuchshuber, Mareike Ernst","doi":"10.1080/13811118.2025.2464061","DOIUrl":"https://doi.org/10.1080/13811118.2025.2464061","url":null,"abstract":"<p><strong>Background: </strong>Alcohol abuse and suicide are significant public health problems. Specifically, more than three million people die each year from alcohol abuse and 700,000 from suicide. Research indicates that alcohol abuse is associated with suicidality, and that there are significant gender differences in both. By means of a large representative population sample, this study quantifies the associations between suicidal ideation and alcohol misuse in the German population.</p><p><strong>Methods: </strong>Based on a survey of 2,513 individuals from 2015, prevalence estimates and logistic regression models were used to estimate the association between suicidal ideation (i.e., past-year suicidal ideation according to the Suicidal Behavior Questionnaire Revised [SBQ-R] and alcohol consumption (i.e., past year high-risk drinking according to the Alcohol Use Disorders Identification Test [AUDIT-C]).</p><p><strong>Results: </strong>High-risk drinking (24.78%) and suicidal ideation (5.09%) were highly prevalent in this representative German population sample. These estimates differed significantly between men and women: Men were more likely to report high-risk drinking (30.14%) compared to women (20.56%), while a greater proportion of women (5.95%) reported suicidal ideation when compared to men (4.00%). Moreover, the association of suicidal ideation and high-risk drinking was weaker in women (OR = 1.64 CI 95% [1.03-2.62]) than in men (OR = 5.62 CI 95% [2.72-11.60]).</p><p><strong>Conclusion: </strong>The high prevalence of suicidal ideation and high-risk drinking in women and underscores the necessity for low-level interventions and public health initiatives aimed at prevention and intervention against the escalation of high-risk drinking and suicidal behavior. Prevention efforts should consider gender-specific patterns of risk.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"1-13"},"PeriodicalIF":2.5,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining Trajectories of Momentary Affect Surrounding NSSI and Alcohol Use: A Network Analysis and Bayesian Approach. 研究自伤和酒精使用的瞬间影响轨迹:网络分析和贝叶斯方法。
IF 2.5 3区 医学
Archives of Suicide Research Pub Date : 2025-02-14 DOI: 10.1080/13811118.2025.2462532
Miguel Blacutt, Brooke A Ammerman
{"title":"Examining Trajectories of Momentary Affect Surrounding NSSI and Alcohol Use: A Network Analysis and Bayesian Approach.","authors":"Miguel Blacutt, Brooke A Ammerman","doi":"10.1080/13811118.2025.2462532","DOIUrl":"https://doi.org/10.1080/13811118.2025.2462532","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to identify specific affective antecedents of non-suicidal self-injury (NSSI) and alcohol use, and to examine affective trajectories before and after these behaviors.</p><p><strong>Method: </strong>Fifty-six undergraduates (71% female, 25% non-White, 20.2 ± 1.3 years old) meeting criteria for probable alcohol or substance use disorder participated in 28-days of ecological momentary assessment, completing four daily surveys assessing affect, self-punishment cognitions, and engagement in NSSI and alcohol use. Contemporaneous and time-lagged graphical vector autoregressive (GVAR) models were used to examine affect dynamics surrounding NSSI and alcohol use. Zero-inflated Bayesian binomial regression was used to investigate the relationship between momentary affect and likelihood of engaging in either NSSI or alcohol at the next prompt. Multilevel modeling was used to examine trajectories of affective states pre- and post-engagement in NSSI and alcohol use.</p><p><strong>Results: </strong>GVAR models revealed significant relationships between jitteriness and being afraid with next timepoint NSSI, and excitement with next timepoint alcohol use. Bayesian regression with horseshoe priors identified self-punishment and loneliness as predictors of NSSI. Moreover, Bayesian regression revealed that excitement predicted alcohol use among those without alcohol use disorder (AUD), while belongingness predicted alcohol use among those with AUD. Multilevel models revealed self-punishment and loneliness followed a negative quadratic trajectory around NSSI events. Excitement and belongingness did not relate to slopes of time.</p><p><strong>Conclusions: </strong>The findings suggest NSSI is used to reduce negative emotional states, whereas alcohol consumption initially enhances positive emotional states in individuals without an AUD and may be used to increase belongingness in those with an AUD.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"1-19"},"PeriodicalIF":2.5,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the Role of Racism in Black Men's Suicide: Revisiting the Interpersonal-Psychological Theory of Suicide. 调查种族主义在黑人自杀中的作用:重新审视自杀的人际心理学理论。
IF 2.5 3区 医学
Archives of Suicide Research Pub Date : 2025-02-13 DOI: 10.1080/13811118.2025.2462528
Leslie B Adams, Aubrey DeVinney, Dahlia Aljuboori, Jasmin Brooks Stephens, Thomasina Watts, Benjamin Lê Cook, Sean Joe, Holly C Wilcox, Roland J Thorpe
{"title":"Investigating the Role of Racism in Black Men's Suicide: Revisiting the Interpersonal-Psychological Theory of Suicide.","authors":"Leslie B Adams, Aubrey DeVinney, Dahlia Aljuboori, Jasmin Brooks Stephens, Thomasina Watts, Benjamin Lê Cook, Sean Joe, Holly C Wilcox, Roland J Thorpe","doi":"10.1080/13811118.2025.2462528","DOIUrl":"https://doi.org/10.1080/13811118.2025.2462528","url":null,"abstract":"<p><strong>Objective: </strong>The Interpersonal-Psychological Theory of Suicide (IPTS) is a well-established framework to assess suicide risk, yet few studies have applied the framework to examine relevance and applicability to suicide phenomenology in Black American men. We address this gap by qualitatively exploring the suitability of the IPTS framework using a psychiatric sample of Black men.</p><p><strong>Method: </strong>We conducted semi-structured interviews with 15 Black adult men (Mean age = 32.1, min:18, max: 79) with a history of suicidal thoughts and behaviors (STBs). We conducted thematic analysis using an inductive and deductive coding approach using Dedoose v. 8.</p><p><strong>Results: </strong>Overall, IPTS constructs were represented in participant narratives. Thwarted belongingness emerged as the most prominent construct of the theory, followed by hopelessness, and suicide capability. Participants noted the role of racism in their STB from multiple levels, including internalized, interpersonal, and structural racism.</p><p><strong>Conclusions: </strong>Black men reported aspects of the Interpersonal Psychological Theory of Suicide (IPTS), notably experiences of social isolation, which were often attributed to racism. Our findings highlight the relative importance of certain IPTS constructs among Black men, namely the significance of thwarted belongingness and its relationship with social marginalization. Our findings identify future areas of expansion for the IPTS framework to capture broader sociocultural dynamics in racialized populations.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"1-14"},"PeriodicalIF":2.5,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Suicidal Behaviour Prior to First Episode Psychosis: Wider and More Widespread Grey-Matter Alterations. 首次精神病发作前的自杀行为:更广泛和更广泛的灰质改变。
IF 2.5 3区 医学
Archives of Suicide Research Pub Date : 2025-02-05 DOI: 10.1080/13811118.2025.2454581
M Canal-Rivero, D Tordesillas-Gutiérrez, M Ruiz-Veguilla, V Ortiz-García de la Foz, E Marco de Lucas, R Romero-Garcia, J Vázquez-Bourgon, R Ayesa-Arriola, B Crespo-Facorro
{"title":"Suicidal Behaviour Prior to First Episode Psychosis: Wider and More Widespread Grey-Matter Alterations.","authors":"M Canal-Rivero, D Tordesillas-Gutiérrez, M Ruiz-Veguilla, V Ortiz-García de la Foz, E Marco de Lucas, R Romero-Garcia, J Vázquez-Bourgon, R Ayesa-Arriola, B Crespo-Facorro","doi":"10.1080/13811118.2025.2454581","DOIUrl":"https://doi.org/10.1080/13811118.2025.2454581","url":null,"abstract":"<p><strong>Introduction: </strong>The prodromal phase preceding the onset of First Episode Psychosis (FEP) is associated with an increased risk of Suicidal Behaviors (SBs). The aim of this study was to identify specific structural brain abnormalities linked to SBs that occur prior to the onset of FEP.</p><p><strong>Methods: </strong>Voxel-based morphometry analyses were used to investigate differences in brain Grey Matter (GM) volume using the CAT12 toolbox within SPM12. Covariates, including gender, age, handedness, intracranial volume, depression severity, and global cognitive functioning, were controlled for as confounding factors.</p><p><strong>Results: </strong>Significant reductions in GM were observed in the left superior temporal gyrus, dorsal posterior cingulate cortex, precuneus, cuneus, anterior cerebellum (p-FWE corrected < 0.05, <i>k</i> > 50) as well as in the right amygdala (0.96 ± 0.06 vs. 1.01 ± 0.05; F = 4.78; <i>p</i> < 0.05) and left amygdala (0.97 ± 0.06 vs. 1.02 ± 0.05; F = 8.97; <i>p</i> = 0.01).</p><p><strong>Conclusions: </strong>History of SB prior to the onset of the psychotic disorder was related to wider and more widespread brain GM alterations. The regions identified are involved in cognitive and emotional processes such as emotional regulation, social cognition, perseverative thinking, and pain tolerance. These findings suggest that structural brain abnormalities related to SB occurring before FEP onset may serve as early biomarkers for identifying individuals at increased risk of suicide.</p>","PeriodicalId":8325,"journal":{"name":"Archives of Suicide Research","volume":" ","pages":"1-15"},"PeriodicalIF":2.5,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexual Fluidity and Suicidal Thoughts and Behaviors in Early and Middle Adulthood: Evidence From the National Longitudinal Study of Adolescent to Adult Health. 成年早期和中期的性流动性与自杀念头和行为:来自青少年到成人健康的全国纵向研究的证据。
IF 2.5 3区 医学
Archives of Suicide Research Pub Date : 2025-01-03 DOI: 10.1080/13811118.2024.2445244
John F Gunn, Zoe Brown, James Ambron
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