Archives of Medical Sciences. Atherosclerotic Diseases最新文献_第7页

Acute myocardial infarction admissions among young adults in the United States: an update on the incidence and burden. 美国年轻人急性心肌梗死入院:发病率和负担的最新情况

Archives of Medical Sciences. Atherosclerotic Diseases Pub Date : 2021-04-09 eCollection Date: 2021-01-01 DOI: 10.5114/amsad.2021.105160

Kamleshun Ramphul, Yogeshwaree Ramphul, Shaheen Sombans, Petras Lohana, Jyotsnav Joynauth

引用次数: 3

Eccentric hypertrophy predicts adverse events in patients undergoing percutaneous coronary intervention for acute coronary syndrome. 偏心肥大预测急性冠脉综合征患者经皮冠状动脉介入治疗的不良事件。

Archives of Medical Sciences. Atherosclerotic Diseases Pub Date : 2021-04-09 eCollection Date: 2021-01-01 DOI: 10.5114/amsad.2021.105175

Edward T Ha, Marc Cohen, Stephen J Peterson, Wilbert S Aronow

{"title":"Eccentric hypertrophy predicts adverse events in patients undergoing percutaneous coronary intervention for acute coronary syndrome.","authors":"Edward T Ha, Marc Cohen, Stephen J Peterson, Wilbert S Aronow","doi":"10.5114/amsad.2021.105175","DOIUrl":"https://doi.org/10.5114/amsad.2021.105175","url":null,"abstract":"Introduction: The effect of the type of left ventricular hypertrophy in patients presenting with an acute coronary syndrome (ACS) on long-term outcomes is ill-defined. The purpose of this study was to investigate the prognostic effect of concentric (CH) or eccentric hypertrophy (EH) on adverse outcomes in patients presenting with ACS undergoing percutaneous coronary intervention (PCI).Material and methods: We analyzed 1-year follow-up data from a single-institution, retrospective, observational study that enrolled 1,153 patients who presented with ACS and were treated with PCI, for whom echocardiographic data were available.Results: Normal geometry was observed in 718 (62.3%) patients, while 27.2% had CH and 10.5% had EH. The primary endpoint of all-cause death (n = 90, 7.8%) occurred in 6.4%, 8.0%, and 14.9% of patients with no, concentric, or eccentric hypertrophy, respectively (p = 0.005). Major adverse cardiac events (MACE - all-cause death, non-fatal myocardial infarction or stroke or hospitalization for bleeding) occurred in 13.9%, 17.8%, 30.6%, respectively (p < 0.001). Age (HR per year = 1.04 (1.02, 1.05), p < 0.001), female gender (HR = 1.56 (1.12, 2.16), p = 0.008), diabetes (HR = 1.49 (1.07, 2.06), p = 0.02), eccentric hypertrophy (HR = 1.58 (1.006, 2.47), p = 0.047), peak troponin I (HR per 1 ng/ml = 1.004 (1.001, 1.006), p = 0.004) and left ventricular ejection fraction < 50% (HR = 1.57 (1.12, 2.20), p < 0.008) were significant predictors of MACE.Conclusions: The presence of eccentric hypertrophy in ACS patients undergoing PCI is an independent predictor of adverse outcomes at 1 year.","PeriodicalId":8317,"journal":{"name":"Archives of Medical Sciences. Atherosclerotic Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1e/04/AMS-AD-6-43772.PMC8117076.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39012823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Association of serum sialic acid concentration with diabetic complications and cardiovascular risk factors in an Indian population. 印度人群血清唾液酸浓度与糖尿病并发症和心血管危险因素的关系

Archives of Medical Sciences. Atherosclerotic Diseases Pub Date : 2021-04-09 eCollection Date: 2021-01-01 DOI: 10.5114/amsad.2021.105142

Pankaj Bansal, Puja Bansal, Rajesh Verma

{"title":"Association of serum sialic acid concentration with diabetic complications and cardiovascular risk factors in an Indian population.","authors":"Pankaj Bansal, Puja Bansal, Rajesh Verma","doi":"10.5114/amsad.2021.105142","DOIUrl":"https://doi.org/10.5114/amsad.2021.105142","url":null,"abstract":"Introduction: Sialic acid (SA) is an acetylated product of neuraminic acid. It acts as a cofactor of many cell surface receptors (e.g. insulin receptors) and is positively associated with most of the serum acute phase reactants. Sialic acid is an important component of serum, which is elevated in diseases such as diabetes and certain malignancies. Diabetes mellitus (DM) is associated with an increase in SA concentration along with other complications. The present study was undertaken to assess the relationship between serum SA and type 2 diabetes.Material and methods: A total of 200 type 2 DM patients, 145 males and 55 females, were included in the study. Also, 100 healthy individuals served as the control group. Parameters assessed included serum SA, lipid profile, urine microalbumin, LDL-C, lipoprotein(a), and serum fibrinogen. The relationship between serum SA and diabetic complications viz retinopathy, nephropathy, and neuropathy was also assessed.Results: Type 2 DM patients had significantly higher levels (p < 0.01) of SA (77.35 ±4.6 mg%) as compared to the control group (68.23 ±7.9 mg%). Increased levels of serum SA were seen in patients with diabetic nephropathy and retinopathy. No correlation was seen between serum SA and diabetic neuropathy.Conclusions: Elevated serum SA concentration is significantly related to type 2 DM and associated cardiovascular risk factors. Further study of acute-phase response markers and mediators as indicators or predictors of diabetic microvascular complications is therefore justified.","PeriodicalId":8317,"journal":{"name":"Archives of Medical Sciences. Atherosclerotic Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/60/95/AMS-AD-6-43766.PMC8117081.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39012821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Smoking and oxidised high-density lipoprotein: a preliminary report. 吸烟与氧化高密度脂蛋白:初步报告。

Archives of Medical Sciences. Atherosclerotic Diseases Pub Date : 2021-04-08 eCollection Date: 2021-01-01 DOI: 10.5114/amsad.2021.105253

Kazuhiko Kotani, Kouichi Miura

引用次数: 3

The impact of COVID-19 on cardiology departments. COVID-19对心内科的影响。

Archives of Medical Sciences. Atherosclerotic Diseases Pub Date : 2021-04-07 eCollection Date: 2021-01-01 DOI: 10.5114/amsad.2021.105063

Kamleshun Ramphul, Petras Lohana, Renuka Verma, Shaheen Sombans

引用次数: 2

A comprehensive review and update on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Coronavirus disease 2019 (COVID-19): what do we know now in 2021? 严重急性呼吸系统综合征冠状病毒 2（SARS-CoV-2）和冠状病毒病 2019（COVID-19）的全面回顾和更新：2021 年我们现在知道了什么？

Archives of Medical Sciences. Atherosclerotic Diseases Pub Date : 2021-04-06 eCollection Date: 2021-01-01 DOI: 10.5114/amsad.2021.105065

Kamleshun Ramphul, Yogeshwaree Ramphul, Yun Park, Petras Lohana, Balkiranjit Kaur Dhillon, Shaheen Sombans

引用次数: 0

COVID-19 infection in type 1 diabetes: emerging data. 1型糖尿病患者中COVID-19感染:新数据

Archives of Medical Sciences. Atherosclerotic Diseases Pub Date : 2021-04-06 eCollection Date: 2021-01-01 DOI: 10.5114/amsad.2021.105064

Cesare Miranda, Elena Rinaldo, Giorgio Zanette

引用次数: 0

Risk factors for Turkish Cypriot patients with coronary artery disease. 土族塞人冠心病患者的危险因素。

Archives of Medical Sciences. Atherosclerotic Diseases Pub Date : 2020-12-30 eCollection Date: 2020-01-01 DOI: 10.5114/amsad.2020.103380

Cenk Conkbayir, Didem Melis Oztas, Murat Ugurlucan

{"title":"Risk factors for Turkish Cypriot patients with coronary artery disease.","authors":"Cenk Conkbayir, Didem Melis Oztas, Murat Ugurlucan","doi":"10.5114/amsad.2020.103380","DOIUrl":"https://doi.org/10.5114/amsad.2020.103380","url":null,"abstract":"Introduction: Ischemic heart disease is the leading cause of death worldwide. In this study, we evaluated the risk factors for Turkish Cypriot ischemic heart disease patients.Material and methods: In this study we examined 7017 patients, retrospectively. 5.9% of the patients had myocardial infarction coronary artery disease (MICAD) and 94.1% of the patients were control patients. The mean age of the study population was 52, and 39.2% were female. The risk factors considered were: age, sex, hypertension (HT), diabetes mellitus (DM), family history of coronary artery disease, smoking, high total cholesterol levels and obesity.Results: Consistently with the presumed risk factors, there was a significant difference between MICAD and control groups in our study for smoking, HT, DM and obesity. However, our study revealed no significant difference for high total cholesterol levels in contrast to the current literature. Assessing the risk factors among male and female patient groups separately, both men and women have the highest risk prevalence for hypertension. Smoking is the second most common risk factor among males, whereas it is the family history of coronary heart disease in the female group. HT, DM and obesity were found to be significant risk factors for both males and females in our study group, while family history was revealed to be significant only in women.Conclusions: Modifiable risk factors such as smoking, hypertension, diabetes mellitus and obesity may be controlled by lifestyle changes and medical therapies, and should be approached with caution for preventing cardiac events. Non-modifiable risk factors such as age, gender, family history and ethnicity should be taken into account for disease prediction.","PeriodicalId":8317,"journal":{"name":"Archives of Medical Sciences. Atherosclerotic Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/49/6b/AMS-AD-5-43201.PMC8609371.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39656834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research progress of typical flavonoids in improving insulin resistance. 典型黄酮类化合物在改善胰岛素抵抗方面的研究进展。

Archives of Medical Sciences. Atherosclerotic Diseases Pub Date : 2020-12-30 eCollection Date: 2020-01-01 DOI: 10.5114/amsad.2020.103472

Shengnan Guo, Li Zhang, Shentao Wu, Hongyi Liu

引用次数: 0

Comparison of bilateral cerebral and somatic tissue oxygenation with near-infrared spectroscopy in cyanotic and acyanotic pediatric patients receiving cardiac surgery. 近红外光谱对接受心脏手术的紫绀和无紫绀儿童双侧大脑和躯体组织氧合的比较。

Archives of Medical Sciences. Atherosclerotic Diseases Pub Date : 2020-12-29 eCollection Date: 2020-01-01 DOI: 10.5114/amsad.2020.103377

Tulay Candan, Muhammet Candan, Cenk Eray Yildiz, Mehmet Gumustas, Selim Erenturk, Yusuf Kenan Yalcinbas

{"title":"Comparison of bilateral cerebral and somatic tissue oxygenation with near-infrared spectroscopy in cyanotic and acyanotic pediatric patients receiving cardiac surgery.","authors":"Tulay Candan, Muhammet Candan, Cenk Eray Yildiz, Mehmet Gumustas, Selim Erenturk, Yusuf Kenan Yalcinbas","doi":"10.5114/amsad.2020.103377","DOIUrl":"10.5114/amsad.2020.103377","url":null,"abstract":"Introduction: Compromise of tissue oxygenation during surgery is associated with increased mortality and morbidity in the postoperative period in patients with congenital cardiac disorders. It may be monitored with near-infrared spectroscopy (NIRS). We aimed to evaluate the tissue oxygenation and factors which may affect it by bilateral cerebral and somatic NIRS levels during cardiopulmonary bypass and to compare the NIRS values of cyanotic and acyanotic patient groups.Material and methods: Two groups of patients with cyanotic and acyanotic congenital heart diseases were included in the study. Each group consisted of 15 patients between 0 and 5 years of age. All data were collected following anesthesia induction (T1), the 10th (T2) and 30th min (T3) of cardiopulmonary bypass (CPB), every 30 min during CPB (T4, T5, T6) and 1 h after (TS). Bilateral and somatic NIRS, blood gases, mean arterial pressure, and temperatures were recorded.Results: Left and right somatic NIRS values in groups at all measurements did not differ significantly. Left and right cerebral NIRS values at T2 and T3 in cyanotic patients were significantly higher than in acyanotic patients. Mean arterial pressure and lactate levels at T1 and T3 measurements were responsible for left cerebral NIRS changes and mean arterial pressure on right cerebral NIRS values.Conclusions: Monitorization of tissue perfusion has critical importance during CPB of patients with congenital heart defects. Oxygenation may easily and reliably be measured with NIRS. Cerebral and somatic NIRS are more pronounced in cyanotic patients and cerebral NIRS is strongly associated with mean arterial pressure and circulating lactate levels.","PeriodicalId":8317,"journal":{"name":"Archives of Medical Sciences. Atherosclerotic Diseases","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/75/be/AMS-AD-5-43199.PMC8609373.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39656833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1