Nicole D DiPiro, Dave Murday, Samantha Donnelly, James S Krause
{"title":"Opioid and benzodiazepine use among a population-based cohort of adults with chronic spinal cord injury: Correspondence between self-report and state prescription monitoring data.","authors":"Nicole D DiPiro, Dave Murday, Samantha Donnelly, James S Krause","doi":"10.1016/j.apmr.2025.04.017","DOIUrl":"https://doi.org/10.1016/j.apmr.2025.04.017","url":null,"abstract":"<p><strong>Objective: </strong>To compare self-reported opioid and benzodiazepine use to rates of prescriptions dispensed among persons with chronic spinal cord injury (SCI), to evaluate the extent of potential underreporting.</p><p><strong>Design: </strong>Cross-sectional self-report assessment (SRA) and retrospective review of prescription monitoring program (PMP) data.</p><p><strong>Setting: </strong>Community dwelling adults in the Southeastern United States (US).</p><p><strong>Participants: </strong>345 adults (>18 years old) with chronic (>1 year) SCI who were identified through a state population-based SCI registry and who responded to SRA opioid use questions in a parent study.</p><p><strong>Interventions: </strong>Not Applicable MAIN OUTCOME MEASURES: Self-reported prescription pain reliever, sedative, and tranquilizer use, and prescriptions dispensed based on PMP data. We compared self-reported past year utilization with records of dispensed prescriptions to assess potential underreporting, defined as reporting \"never\" using either opioids (pain relievers) or benzodiazepines (sedatives/tranquilizers) in the past year, but having had two or more respective prescriptions dispensed in the year prior to the SRA.</p><p><strong>Results: </strong>Among the 345 participants who responded to the opioid use questions, we were able to match 252 to the PMP; reasons for not matching include not filling a controlled substance prescription in-state, either due to lack of reportable prescriptions or the prescription was dispensed out of state. Evaluating each prescription medication, rates of underreporting for each drug ranged from 0.4% - 4% for Hydrocodone, Oxycodone, Tramadol, Codeine, Buprenorphine and Hydromorphone. There was 100% agreement in the self-reported use and dispensed records for Fentanyl, Oxymorphone, Meperidine, and Methadone. The rates of potential underreporting of Benzodiazepines were less than 2%. Overall, of the 252 matched individuals, 11% underreported opioids (2 or more prescriptions dispensed) and 1% underreported benzodiazepines.</p><p><strong>Conclusions: </strong>The findings suggest considerable agreement between self-reported and dispensed prescription medication use, and only minimal potential underreporting of select opioids and benzodiazepines, confirming the appropriateness of self-report of these prescription medications with people with SCI.</p>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olivia Crozier, Anahita Amirpour, Pooja Jethani, Mark Bayley, Urvashy Gopaul
{"title":"Parenting After Stroke: A Practical Guide for Parents With Young Children.","authors":"Olivia Crozier, Anahita Amirpour, Pooja Jethani, Mark Bayley, Urvashy Gopaul","doi":"10.1016/j.apmr.2025.04.006","DOIUrl":"https://doi.org/10.1016/j.apmr.2025.04.006","url":null,"abstract":"","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyun Jung Lee, Jae Young Kim, Sung Wook Song, Shin-Young Yim
{"title":"Cancer incidence and risk in children and adolescents with intellectual disability in South Korea.","authors":"Hyun Jung Lee, Jae Young Kim, Sung Wook Song, Shin-Young Yim","doi":"10.1016/j.apmr.2025.04.023","DOIUrl":"https://doi.org/10.1016/j.apmr.2025.04.023","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate cancer risk and identify distinctive cancer patterns in children and adolescents with intellectual disability (ID) in South Korea, where comprehensive research in this population remains limited.</p><p><strong>Design: </strong>Retrospective cohort study SETTING: Nationwide population-based data from the National Health Insurance Service-National Health Information Database (NHIS-NHID) in South Korea (2004-2021) PARTICIPANTS: This study included 75,491 individuals with ID aged 2-18 years and 917,699 age- and sex-matched controls without ID (1:10 matching ratio to maximize statistical power).</p><p><strong>Interventions: </strong>Not applicable.</p><p><strong>Main outcome measure(s): </strong>Cancer incidence and associated risk factors, including comorbidities, demographic characteristics, and socioeconomic status, analyzed using Cox proportional hazard models.</p><p><strong>Results: </strong>Children and adolescents with ID had a significantly higher overall cancer incidence and risk compared to the control group (adjusted HR: 1.1; 95% CI: 1.005-1.204). Those with medical comorbidities faced an even greater risk (adjusted HR: 1.96; 95% CI: 1.75-2.194). Significant risk factors included older age (16 to ≤18 years vs. 2 to <6 years: HR 3.529; 95% CI: 3.321-3.749) and lower socioeconomic status (medical aid vs. high-income: HR 0.863; 95% CI: 0.788-0.945). The top five cancer sites in the ID group were renal pelvis and ureter, heart, mediastinum, and pleura, acute lymphoblastic leukemia, brain, and ovary.</p><p><strong>Conclusion: </strong>Children and adolescents with ID in South Korea exhibit a distinct cancer risk profile, with elevated cancer incidence compared to the control group. Tailored cancer prevention, early detection strategies, and healthcare utilization policies are essential to address these needs of this vulnerable group.</p>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrigendum.","authors":"","doi":"10.1016/j.apmr.2025.01.417","DOIUrl":"https://doi.org/10.1016/j.apmr.2025.01.417","url":null,"abstract":"","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Real-Time Assessment of Resilience in Individuals with Spinal Cord Injury and Chronic Pain: A Feasibility, Reliability, and Validity Study.","authors":"Duygu Kuzu, Anna L Kratz","doi":"10.1016/j.apmr.2025.04.022","DOIUrl":"https://doi.org/10.1016/j.apmr.2025.04.022","url":null,"abstract":"<p><strong>Objective: </strong>This observational study examined the feasibility, between-person reliability, and convergent and discriminant validity of an Ecological Momentary Assessment (EMA) measure of resilience in individuals with spinal cord injury (SCI) and chronic pain.</p><p><strong>Design: </strong>Participants completed self-report assessments of resilience twice a day for seven days using 6-item EMA measure adapted from the SCI-QOL Resilience item bank. Data were collected via smartphone.</p><p><strong>Setting: </strong>General community.</p><p><strong>Participants: </strong>Individuals with SCI and chronic pain (N=53, 54.7% male, 45.3% female).</p><p><strong>Interventions: </strong>Not applicable.</p><p><strong>Main outcome measures: </strong>Besides the 6-item EMA resilience measure, we included the full SCI-QOL Resilience Item Bank, the Connor-Davidson Resilience Scale (CD-RISC), the PROMIS Depression Short Form, the SCI-QOL Anxiety Short Form, the NIH Toolbox Perceived Stress Survey, the SCI-QOL Positive Affect and Well-Being Short Form, and the SCI-QOL Ability to Participate in Social Roles and Activities.</p><p><strong>Results: </strong>Our results showed that the Resilience EMA measure revealed high feasibility with an overall response rate of 88% and strong between-person reliability (above .90). The measure also demonstrated good convergent validity with related constructs, such as depression, anxiety, and social participation, and good discriminant validity with unrelated factors like age and injury level.</p><p><strong>Conclusion: </strong>Our findings suggest that the EMA resilience measure is a reliable and valid tool for capturing the dynamic nature of resilience in real time. Our study highlights the importance of the application of a real-time assessment, given that understanding daily functioning and contributes to more person-centered rehabilitation interventions for individuals with SCI and chronic pain.</p>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimal Exercise Modalities and Doses for Alleviating Dyspnea Symptoms and Enhancing Exercise Capacity in Patients with Chronic Obstructive Pulmonary Disease: A Network and Dose-Response Meta-Analysis.","authors":"Jingyi Xie, Jindong Guo, Bin Wang","doi":"10.1016/j.apmr.2025.05.001","DOIUrl":"https://doi.org/10.1016/j.apmr.2025.05.001","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the optimal exercise modalities and doses for alleviating dyspnea and enhancing exercise capacity in patients with chronic obstructive pulmonary disease (COPD).</p><p><strong>Data sources: </strong>PubMed, Cochrane, Embase, and Web of Science were searched until June 2024.</p><p><strong>Study selection: </strong>Randomized controlled trials (RCTs) on dyspnea and exercise capacity in patients with COPD were included.</p><p><strong>Data extraction: </strong>Exercises were compared using a network and dose-response meta-analysis. Two authors independently extracted the data and assessed bias risk.</p><p><strong>Data synthesis: </strong>The study included 46 RCTs (2,363 participants). Continuous aerobic training (MD=55.2; 95% CrI: 28.1, 84.5.</p><p><strong>Grade: </strong>Low), interval training (MD=84.5; 95% CrI: 24.6, 145.</p><p><strong>Grade: </strong>Low), Qigong (MD=33.3; 95%CrI: 10.4, 58.1.</p><p><strong>Grade: </strong>Low), and resistance training (MD=41.5; 95% CrI: 7.27, 77.7.</p><p><strong>Grade: </strong>Low) improved 6-minute walk distance (6MWD). Qigong (MD=-8.20; 95%CrI: -15.6, -1.50.</p><p><strong>Grade: </strong>Low) and yoga (MD=-28.3; 95%CrI: -48.1, -8.61.</p><p><strong>Grade: </strong>Low) showed significant improvements in St. George's Respiratory Questionnaire (SGRQ). Resistance training (MD=12.1; 95%CrI: 4.62, 18.7.</p><p><strong>Grade: </strong>Low) correlated positively with forced expiratory volume in 1 second (FEV1), while Qigong correlated positively with forced vital capacity (FVC) (MD=0.378; 95%CI: 0.087, 0.620.</p><p><strong>Grade: </strong>Low). Interval training, yoga, resistance training, and Qigong ranked the highest in 6MWD, SGRQ, FEV1, and FVC. The dose-response curve revealed an increasing trend in the effect of exercise intensity on enhancing 6MWD with intensified exercise levels. Regarding SGRQ scores, the optimal effect was observed at an exercise intensity of 620 METs-min/week (MD=-7.07, 95% CrI: -12.23, -1.87). The optimal exercise intensity was 350 METs-min/week for FEV1 (MD=0.44, 95% CrI: 0.09, 0.80) and FVC (MD=0.44, 95% CrI: 0.09, 0.80).</p><p><strong>Conclusion: </strong>Low quality evidence shows that Interval training, yoga, resistance training, and Qigong effectively improved dyspnea and exercise capacity in patients with COPD. Optimal exercise doses vary across outcomes, necessitating personalized adjustments based on health status.</p>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brad D Hendershot, Morgan Armes, Binni Khatri, Alison L Pruziner, Barri L Schnall, Meghan Tullos, Christopher L Dearth, Benjamin K Potter, Jonathan A Forsberg
{"title":"Performance-Based Functional Outcomes Twelve and Twenty-Four Months after Transfemoral Osseointegration in Service Members with Traumatic Unilateral and Bilateral Lower Limb Loss.","authors":"Brad D Hendershot, Morgan Armes, Binni Khatri, Alison L Pruziner, Barri L Schnall, Meghan Tullos, Christopher L Dearth, Benjamin K Potter, Jonathan A Forsberg","doi":"10.1016/j.apmr.2025.04.021","DOIUrl":"https://doi.org/10.1016/j.apmr.2025.04.021","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate functional outcomes at 12-months and 24-months after transfemoral osseointegration (OI), using established performance-based assessments DESIGN: Pre-post observational, single cohort SETTING: Military treatment facility PARTICIPANTS: Forty-seven service members (age=38±9y) with traumatic unilateral (n=22) and bilateral (n=25) lower limb loss. Before OI, n=2 unilateral and n=7 bilateral were not ambulatory on full-length prostheses.</p><p><strong>Intervention: </strong>Transfemoral OI (two-stage threaded implant) MAIN OUTCOME MEASURES: Six-Minute Walk Test (6MWT), Timed Up and Go (TUG), Four Square Step Test (4SST), [Bilateral] Amputee Mobility Predictor ([B]AMP), Comprehensive High-level Activity Mobility Predictor (CHAMP).</p><p><strong>Results: </strong>For both unilateral and bilateral cohorts, median performance-based functional outcomes were similar at 12-months and 24-months after vs. before OI: 6MWT (373 and 385 vs. 417m; p>0.31), TUG (9.7 and 9.6 vs. 9.8s; p>0.53), 4SST (9.5 and 10.6 vs. 10.8s; p>0.11), and CHAMP (12.6 and 10.6 vs. 12.3; p>0.44). Median BAMP scores were greater at 12-months (p=0.029) and 24-months (p=0.014) after vs. before OI among the bilateral cohort (30 and 35 vs. 16); median AMP scores were similar (p>0.10) among the unilateral cohort across timepoints (39 and 43 vs. 40). Among the 9 participants not ambulating with full-length prostheses before OI, 8 became capable of ambulation on full-length prostheses after by 24-months after OI.</p><p><strong>Conclusions: </strong>While a lack of improvement in these particular outcomes is not exclusively suboptimal, particularly considering median scores at baseline reported here generally exceed other cohorts (both before and sometimes even after OI), these findings contrast with previous self-reported improvements in function after OI among service members with traumatic lower limb loss. As such, these data seemingly emphasize the importance of a comprehensive approach with both subjective and objective (multidisciplinary) outcomes for more fully characterizing OI, particularly within unique patient populations like young service members with traumatic lower limb loss.</p>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ronald Lee Kirby, Kim Parker, Alistair Lloyd Maksym, Suzanne Patricia Frances Salsman, Christopher John Theriault, Bahareh Yavarizadeh, Fitsum Hadgu Woldeyohannes
{"title":"Relationships between wheelchair provision time for hospital inpatients and their lengths of stay and costs of hospitalization: a cohort study.","authors":"Ronald Lee Kirby, Kim Parker, Alistair Lloyd Maksym, Suzanne Patricia Frances Salsman, Christopher John Theriault, Bahareh Yavarizadeh, Fitsum Hadgu Woldeyohannes","doi":"10.1016/j.apmr.2025.04.019","DOIUrl":"https://doi.org/10.1016/j.apmr.2025.04.019","url":null,"abstract":"<p><strong>Objectives: </strong>To test the hypotheses that Wheelchair Provision Time (WPT) (from when a loaner wheelchair was ordered to when the wheelchair arrived at the hospital site) has a significant relationship with Length of Stay (LOS) and total Cost of Hospitalization (COH).</p><p><strong>Design: </strong>Cohort study.</p><p><strong>Setting: </strong>Hospital inpatient units in the Central Zone of Nova Scotia Health (NSH).</p><p><strong>Participants: </strong>97 inpatients.</p><p><strong>Intervention: </strong>Order for loaner wheelchair placed during their admissions.</p><p><strong>Main outcome measures: </strong>Demographic, clinical and process data from four available databases from which we derived WPT, LOS and COH. To test the hypotheses, we used Spearman correlation coefficients, negative binomial regression for LOS (n = 90) and linear regression for COH (n = 69).</p><p><strong>Results: </strong>The median values for WPT, LOS and total COH were 3.8 days, 51.0 days and $43,062 Canadian dollars (CADs). Multivariable regression revealed that WPT was associated to a statistically significant extent with LOS (p = 0.0049) (a 18% increase in LOS for each additional day in WPT), but not with COH. However, LOS was associated to a statistically significant extent with COH (p < 0.0001). The Spearman correlation between LOS and COH was 0.8915 (p < 0.0001).</p><p><strong>Conclusions: </strong>Statistically significant associations exist between WPT and LOS and between LOS and COH. Although this study does not establish causality and further research is needed, our findings suggest that more rapid provision of loaner wheelchairs to hospital inpatients could have a positive impact on the health-care system.</p>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jenifer M Pugliese, J Megan Sions, Patrick J Knox, Ryan T Pohlig, Gregory E Hicks
{"title":"CLINICAL CHARACTERIZATION OF HIP SUBGROUPS IN GERIATRIC CHRONIC LOW BACK PAIN.","authors":"Jenifer M Pugliese, J Megan Sions, Patrick J Knox, Ryan T Pohlig, Gregory E Hicks","doi":"10.1016/j.apmr.2025.04.018","DOIUrl":"https://doi.org/10.1016/j.apmr.2025.04.018","url":null,"abstract":"<p><strong>Objective: </strong>To investigate and compare the clinical profiles of three previously established hip-based subgroups of older adults with chronic low back pain (LBP) using data from multiple domains.</p><p><strong>Design: </strong>Cross-sectional analysis of baseline cohort study data.</p><p><strong>Setting: </strong>Clinical Research Laboratory.</p><p><strong>Participants: </strong>250 Community dwelling older adults with chronic LBP.</p><p><strong>Interventions: </strong>Not applicable.</p><p><strong>Main outcome measures: </strong>Clinical profiles of the previously derived subgroups were established. Pain quality and dispersion were captured with the McGill Pain Questionnaire. Self-efficacy was measured using the Low Back Activity Confidence Scale. Catastrophic thoughts about LBP were captured with the Pain Catastrophizing Scale. Trunk mobility was measured with an inclinometer. Trunk muscle function was captured through standardized muscle endurance testing and ultrasound measures of muscle activity. One-way analysis of variance was used to analyze between-group differences.</p><p><strong>Results: </strong>Each chronic LBP subgroup was named based on the level of hip strength and hip symptoms: weak/symptomatic (WS), weak/non-symptomatic (WNS) and strong/non-symptomatic (SNS). The WS subgroup had distinctly worse levels of pain quality, dispersion, catastrophizing and self-efficacy, compared to the other two subgroups. In contrast, the SNS subgroup, as compared to the other subgroups, had greater thoracolumbar flexion, greater trunk muscle endurance and better psychological profiles.</p><p><strong>Conclusion: </strong>The unique clinical profile of each subgroup underscores how important it is to consider the heterogeneous nature of chronic LBP in the geriatric population when developing treatment approaches. The clinical characterization of these subgroups across multiple rehabilitation-focused domains may optimize the development of tailored interventions for each subgroup.</p>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143975148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rebecca B Ramalho, Thais C Chaves, Berend Terluin, Luiz F A Selistre
{"title":"Minimal Important Changes of Common Outcome Measures of Physical Function in Individuals with Knee Osteoarthritis: A Prospective Clinical Study.","authors":"Rebecca B Ramalho, Thais C Chaves, Berend Terluin, Luiz F A Selistre","doi":"10.1016/j.apmr.2025.04.016","DOIUrl":"https://doi.org/10.1016/j.apmr.2025.04.016","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the Minimal Important Change (MIC) for the 40-meter Fast Paced Walk Test (40m FPWT), the 30-second Chair Stand Test (30s CST), 11-step Stair Climb Test (11-step SCT) and the Western Ontario and McMaster Universities Osteoarthritis Index - physical function subscale (WOMAC-PF) in individuals with knee osteoarthritis (KOA) according to three methods described in the literature.</p><p><strong>Design: </strong>A prospective clinical study.</p><p><strong>Setting: </strong>Department of Physiotherapy at Federal University of São Carlos (Brazil) PARTICIPANTS: A total of 107 participants.</p><p><strong>Interventions: </strong>Not applicable.</p><p><strong>Main outcome measure: </strong>Performance-based tests and WOMAC-PF were applied. After six months the Global Perceived Effect (GPE) scale was used to evaluate changes in physical function. A GPE cut-off score was established to categorize participants as improved or not improved. The MIC<sub>mean</sub>, MIC<sub>ROC</sub>, and MIC<sub>adjusted</sub> were calculated. Anchor reliability was assessed through longitudinal confirmatory factor analysis.</p><p><strong>Results: </strong>Out of 80 study participants, 19 were in the improved group. The MIC<sub>mean</sub> of the subgroups ranged from 0.07 to 0.29 m/s for the 40m FPWT, from 2.07 to 5.29 stands for the 30s CST, from 2.14 to 5.58s for the 11-step SCT, and from 4.21 to 27 for the WOMAC-PF. The MIC<sub>ROC</sub> values were 0.14 m/s for the 40m FPWT, 1.5 stands for the 30s CST, 1.79s for the 11-step SCT and 4.5 for the WOMAC-PF. The MIC<sub>adjusted</sub> values were 0.10 m/s for the 40m FPWT, 0.7 stands for the 30s CST, 4.0s for the 11-step SCT and 12.8 for the WOMAC-PF.</p><p><strong>Conclusion: </strong>The MIC<sub>adjusted</sub> method considers both the proportion of improved patients and the reliability of transition ratings, making it preferable to MIC<sub>mean</sub> and MIC<sub>ROC</sub>. However, more high-quality studies are needed to assess its performance in samples with floor or ceiling effects.</p>","PeriodicalId":8313,"journal":{"name":"Archives of physical medicine and rehabilitation","volume":" ","pages":""},"PeriodicalIF":3.6,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}