Annals of Coloproctology最新文献

{"title":"Tailoring surgery for obstructed defecation and its evolution into ineffective defecation: a new staging of the syndrome and a site-specific decision algorithm.","authors":"Adolfo Renzi","doi":"10.3393/ac.2025.01613.0230","DOIUrl":"10.3393/ac.2025.01613.0230","url":null,"abstract":"","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":"42 3","pages":"372-375"},"PeriodicalIF":2.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing anastomosis safety with intraoperative perfusion assessment: a visual grading system for tailoring resection and ostomy formation in sigmoid colon and rectal cancer surgery.","authors":"Soo Young Oh, Seok-Byung Lim, Eu-Tteum Choi, Min Hyun Kim, Young Il Kim, Jong Lyul Lee, Yong Sik Yoon, Chan Wook Kim, In Ja Park, Chang Sik Yu","doi":"10.3393/ac.2025.01081.0154","DOIUrl":"10.3393/ac.2025.01081.0154","url":null,"abstract":"<p><strong>Purpose: </strong>Anastomotic leakage remains challenging in left-sided colorectal surgery. We previously proposed a 5-grade visual grading system based on marginal vessel bleeding, indicating that good (grades A/B) to moderate (grade C) perfusion generally ensures safe anastomosis. However, borderline perfusion (grade C) carried additional risk, particularly among older patients or those with comorbidities. We refined this system to determine whether selective resection of grade C bowel could improve perfusion and guide ostomy diversion decisions.</p><p><strong>Methods: </strong>Eighty patients with left-sided colorectal cancer underwent curative-intent surgery. Intraoperatively, both marginal vessel and mucosal bleeding were assessed. Initial perfusion grade-guided decision-making: grades A/B proceeded to anastomosis, whereas for grade C, additional resection was performed to upgrade perfusion. Ostomy diversion was performed for persistent grade C or prophylactically in high-risk patients.</p><p><strong>Results: </strong>Among 80 patients, 67 (83.8%) had grades A/B and 13 (16.3%) were initial grade C. Additional resection (mean, 4.5 cm) upgraded perfusion to final grade B in 9 patients (69.2%), enabling primary anastomosis. Overall, 12 patients (15.0%) received ostomy: 4 for persistent grade C and 8 for high-risk indications despite adequate final perfusion. All 76 patients with final grade A/B achieved 0% anastomotic leakage and ischemic colitis. Grade C patients had longer operative times (108.8 minutes vs. 86.6 minutes, P=0.003) with additional procedures. Patients requiring diversion were older with more comorbidities.</p><p><strong>Conclusion: </strong>By actively applying the intraoperative visual grading system to upgrade borderline perfusion, we achieved low postoperative complication rates. This approach provides a simple and practical strategy to support intraoperative clinical judgment and optimize anastomotic safety.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":"42 3","pages":"303-314"},"PeriodicalIF":2.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of escin combined with micronized purified flavonoid fraction in controlling bleeding and preventing recurrence of acute internal hemorrhoids: a randomized controlled trial.","authors":"Witcha Vipudhamorn, Pawit Sutharat, Suwan Sanmee, Ekkarin Supatrakul, Sunhawit Junrungsee","doi":"10.3393/ac.2025.01207.0172","DOIUrl":"10.3393/ac.2025.01207.0172","url":null,"abstract":"<p><strong>Purpose: </strong>Recurrence after initial control of acute internal hemorrhoidal bleeding remains a common and clinically relevant challenge. Escin, a venotonic and anti-inflammatory compound, may augment the therapeutic effects of micronized purified flavonoid fraction (MPFF). This study aimed to evaluate whether the addition of escin to MPFF reduces recurrence of acute internal hemorrhoidal bleeding.</p><p><strong>Methods: </strong>In this double-blind randomized controlled trial, adults with grade 1 or 2 acute bleeding internal hemorrhoids received MPFF 3,000 mg/day for 7 days in combination with either escin 120 mg/day or a matched placebo. Patients who achieved hemostasis subsequently continued MPFF 1,000 mg/day with escin or placebo for 2 months. The primary endpoint was recurrence within 90 days, defined clinically and confirmed by proctoscopy. Secondary outcomes included time to hemostasis, the Short Health Scale for Hemorrhoids (SHSHD), and safety outcomes.</p><p><strong>Results: </strong>Among the 108 patients who achieved hemostasis, recurrence occurred in 0% vs. 7.84% at 1 month and 7.02% vs. 23.52% at 3 months in the escin and placebo groups, respectively. Combination therapy was associated with a significantly reduced risk of recurrence (hazard ratio, 3.95; P=0.009). Time to bleeding cessation was shorter in the escin group (median, 2 days vs. 4 days; P<0.001). Improvement in SHSHD scores was greater with escin. No adverse events were observed in either group.</p><p><strong>Conclusion: </strong>The combination of escin and MPFF reduces recurrence and accelerates symptom resolution in acute internal hemorrhoidal bleeding, with a favorable safety profile.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier: NCT06748014.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":"42 3","pages":"273-280"},"PeriodicalIF":2.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13334321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the timing of additional surgery after noncurative endoscopic resection of early colorectal cancer on perioperative and oncological outcomes: a single-center retrospective cohort study.","authors":"Shuhua Zhuo, Yijuan Liu, Kaiyan Wei, Jiantao Zheng, Lin Zhang","doi":"10.3393/ac.2025.01319.0188","DOIUrl":"10.3393/ac.2025.01319.0188","url":null,"abstract":"<p><strong>Purpose: </strong>For early colorectal cancer (CRC) following noncurative endoscopic resection, additional curative surgery is the standard of care, but the optimal timing remains unclear. This study investigated the effect of the interval between procedures on surgical complexity, complications, and oncological outcomes.</p><p><strong>Methods: </strong>This retrospective study included 112 patients with early CRC who underwent additional laparoscopic surgery after noncurative endoscopic resection between August 2019 and August 2024. Clinical and pathological data were collected, with primary endpoints focused on surgical difficulty (operative duration and intraoperative blood loss). Statistical analyses were performed using multivariate analysis of variance, logistic regression, and receiver operating characteristic curve analysis.</p><p><strong>Results: </strong>The interval between procedures was not significantly associated with surgical difficulty or lymph node metastasis (P>0.05). Multivariate analysis did not identify an optimal timing point for surgery. However, a longer waiting time was independently associated with an increased risk of residual tumor (odds ratio, 1.09; 95% confidence interval, 1.03-1.16; P=0.004). Furthermore, lymphovascular invasion and elevated preoperative carcinoembryonic antigen levels were identified as independent predictors of lymph node metastasis. A higher preoperative lymphocyte ratio was associated with an increased risk of postoperative intra-abdominal infection (r=0.243, P=0.010).</p><p><strong>Conclusion: </strong>In the era of laparoscopic surgery, the timing of additional surgery does not appear to be the primary determinant of surgical difficulty in CRC. Clinical decision-making should prioritize high-risk pathological features, such as lymphovascular invasion, rather than rigid adherence to a predetermined waiting period. Strategically delaying surgery may facilitate the selection of patients without residual disease, thereby helping to avoid unnecessary procedures.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":"42 3","pages":"345-354"},"PeriodicalIF":2.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D maintenance in postoperative patients (D-ECISIVE): a study protocol for a randomized controlled trial.","authors":"Glenys Shu Wei Quak, James Jia Dong Wang, Candy Yap, Olivia Soh, Olivia Wong, Cherie Tong, Phoebe Tay, Hui-Bing Lee, Shi-Min Mah, Frederick H Koh","doi":"10.3393/ac.2025.01179.0168","DOIUrl":"10.3393/ac.2025.01179.0168","url":null,"abstract":"<p><strong>Background: </strong>Vitamin D plays a critical role in maintaining calcium and phosphate homeostasis, muscle health, and postoperative recovery. Patients undergoing surgery face an increased risk of vitamin D insufficiency because of reduced sun exposure, altered nutritional intake, and preexisting deficiencies, factors that may compromise muscle function and impair recovery and quality of life. However, there is currently no standardized protocol for postoperative vitamin D maintenance. Therefore, this study aims to evaluate whether monthly high-dose vitamin D supplementation (50,000 IU) maintains serum vitamin D levels and improves postoperative muscle function and quality of life compared with standard care.</p><p><strong>Study design: </strong>This single-center, open-label, randomized controlled trial will recruit adults aged 21 to 65 years who have undergone major surgery and have serum 25-hydroxyvitamin D levels between 30 and 50 ng/mL at 4 to 6 weeks postoperatively. Participants will be randomly assigned in a 1:1 ratio to receive either monthly high-dose vitamin D supplementation (50,000 IU cholecalciferol) for 6 months or standard postoperative care without routine vitamin D supplementation. Outcome assessors will be blinded to group allocation. The primary outcome is maintenance of serum 25-hydroxyvitamin D levels at 3 months after the intervention. Secondary outcomes include serum vitamin D levels at 6 months; assessments of muscle function, including handgrip strength, 6-minute walk test, and 5 times chair stand test; evaluations of muscle quality using the intramuscular adipose tissue index; and quality of life measured by the EuroQoL 5-dimension 3-level (EQ-5D-3L) instrument.</p><p><strong>Outcome: </strong>This study will provide evidence on whether monthly high-dose vitamin D supplementation supports muscle recovery and quality of life in postoperative patients. The findings may help establish standardized guidelines for postoperative vitamin D maintenance and inform future supplementation strategies in surgical populations.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier: NCT06708741. Registered on November 26, 2024.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":"42 3","pages":"364-371"},"PeriodicalIF":2.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robotic versus laparoscopic surgery for mid and low rectal cancer: a propensity score-matched analysis of short-term outcomes and costs.","authors":"Aaron Seah Wei Ming, Isaac Seow-En, Koo Chee Hoe, Lionel Raphael Chen Hui, Yvonne Ng Ying Ru, Ngo Nye Thane, Ivan Tan En-Howe, Rachel Lee Shi Yi, Emile Kwong Wei Tan","doi":"10.3393/ac.2025.01508.0215","DOIUrl":"10.3393/ac.2025.01508.0215","url":null,"abstract":"<p><strong>Purpose: </strong>Robotic and laparoscopic approaches to rectal cancer surgery yield comparable short-term outcomes; however, comparative inpatient costs, particularly when stratified by tumor level, remain insufficiently characterized. This study compared short-term clinical and pathological outcomes, as well as index hospitalization costs, for minimally invasive surgery in patients with mid and low rectal cancer.</p><p><strong>Methods: </strong>All consecutive patients with mid (5-10 cm from the anal verge) and low (<5 cm from the anal verge) rectal cancer who underwent elective minimally invasive surgery between January 2018 and December 2023 were identified. One-to-one propensity score matching was performed using the following covariates: age, sex, body mass index, American Society of Anesthesiologists physical status, tumor level, receipt of neoadjuvant therapy, and presence of a defunctioning stoma. Outcomes and cost components were compared overall and stratified by tumor level.</p><p><strong>Results: </strong>After matching, 282 patients were included (laparoscopic surgery, n=141; robotic surgery, n=141). Median operative time was longer in the robotic group (368 minutes vs. 325 minutes, P=0.007), whereas the median postoperative length of stay was similar between groups (6.0 days vs. 6.0 days, P=0.255). Rates of conversion to open surgery, anastomotic leak, 30-day mortality, and 30-day readmission did not differ significantly. Histopathological indicators of resection quality, including lymph node yield, margin clearance, and completeness of total mesorectal excision, were comparable. Mean index hospitalization cost was higher in the robotic group (SGD 37,436 vs. SGD 31,724; difference, SGD 5,713; P=0.008), with a greater difference observed in mid rectal cancer (SGD 8,606; P=0.008) than in low rectal cancer (SGD 1,811; P=0.465).</p><p><strong>Conclusion: </strong>Robotic and laparoscopic surgery yielded comparable short-term clinical and pathological outcomes. Although costs were higher with robotic surgery, the cost differential was smaller for low rectal cancer, identifying this subgroup as a priority for prospective evaluation of clinical and economic value.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":"42 3","pages":"355-363"},"PeriodicalIF":2.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence in anal fistula: mapping evidence to IDEAL stages.","authors":"Vipul D Yagnik, Prema Ram Choudhary, Pankaj Garg","doi":"10.3393/ac.2025.01494.0213","DOIUrl":"10.3393/ac.2025.01494.0213","url":null,"abstract":"<p><p>Artificial intelligence (AI) is increasingly applied in colorectal and anorectal surgery, particularly for complex conditions such as anal fistula (AF). Conventional diagnostic and therapeutic approaches remain limited by intricate anatomy, high recurrence risk, and the need to preserve continence. This narrative review, evaluates the role of AI in AF and related anorectal disorders, with evidence mapped to the IDEAL (idea, development, exploration, assessment, and long-term follow-up) framework (stages 1-4, with stage 2 subdivided into 2a and 2b). Relevant literature was identified through targeted searches of PubMed, Embase, and Scopus. Studies investigating AI applications in AF or related anorectal conditions, including imaging, surgical planning, predictive modeling, and functional assessment, were included. Evidence was categorized according to IDEAL stages, ranging from proof-of-concept to long-term quality assurance. AI demonstrates potential across 4 key domains: (1) preoperative imaging (stages 1-2b); (2) intraoperative planning and assistance (stages 1-2a); (3) predictive modeling (stages 2a-2b); and (4) broader anorectal applications, including anorectal manometry and the EndoFLIP (endoluminal functional lumen imaging probe) procedure (stages 1-2b). Feasibility studies report high diagnostic performance, particularly for magnetic resonance imaging and computed tomography-based deep learning models; however, these findings are constrained by small sample sizes, limited external validation, and challenges related to workflow integration. Overall, AI has the potential to enhance diagnostic accuracy, surgical planning, and functional assessment in AF and related disorders. However, most studies remain within early IDEAL stages (1-2b), highlighting the need for multicenter validation, cost-effectiveness analyses, and robust ethical frameworks before widespread clinical implementation.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":"42 3","pages":"264-272"},"PeriodicalIF":2.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on \"Long-term outcomes of intramural rectal botulinum toxin injections for urge fecal incontinence: a salvage therapy for sacral neuromodulation nonresponders?\"","authors":"Nabil Mohammad Azmi, Mohd Firdaus Mohd Hayati, Zairul Azwan Mohd Azwan","doi":"10.3393/ac.2025.01326.0189","DOIUrl":"10.3393/ac.2025.01326.0189","url":null,"abstract":"","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":"42 3","pages":"381-382"},"PeriodicalIF":2.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327888/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for postoperative urinary retention in benign anorectal diseases: a case-control study.","authors":"Hui Zhang, Liang Zhang, Shijie Qu","doi":"10.3393/ac.2025.00857.0122","DOIUrl":"10.3393/ac.2025.00857.0122","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to explore the incidence of postoperative urinary retention (POUR) and the associated risk factors in patients with benign anorectal diseases.</p><p><strong>Methods: </strong>A retrospective analysis was conducted using data from patients who underwent surgery for benign anorectal diseases between June 2020 and October 2023. Patients were categorized into the POUR group and the non-POUR group according to the occurrence of postoperative urinary retention. Univariate analysis and multivariate logistic regression analyses were performed to identify risk factors.</p><p><strong>Results: </strong>The incidence of POUR following surgery for benign anorectal diseases was 9.4%. Female sex (P<0.001), being married (P<0.001), age over 60 years (P=0.013), preoperative diabetes (P<0.001), benign prostatic hyperplasia in men (P=0.001), elevated preoperative serum creatinine levels (P=0.015), mixed hemorrhoids (P=0.001), subarachnoid anesthesia (P<0.001), and general anesthesia (P<0.001) were identified as independent risk factors for POUR in patients with benign anorectal diseases. In addition, the POUR group demonstrated a significantly longer length of hospital stay compared with the non-POUR group (P<0.05).</p><p><strong>Conclusion: </strong>POUR results from the combined effects of multiple factors. Through the identification and analysis of POUR-related risk factors, interventions such as regulating perioperative glycemic control, optimizing renal function, and selecting appropriate anesthesia techniques may further reduce its incidence.</p><p><strong>Trial registration: </strong>Chinese Clinical Trial Register identifier: ChiCTR2500097230.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":"42 3","pages":"281-292"},"PeriodicalIF":2.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327895/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148374253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing lymph node harvest in laparoscopic colorectal cancer: predictors and station-specific lymph node submission solutions.","authors":"Chun Gao, Sheng Zhang","doi":"10.3393/ac.2025.01123.0160","DOIUrl":"10.3393/ac.2025.01123.0160","url":null,"abstract":"<p><strong>Purpose: </strong>Adequate lymph node yield is crucial for accurate staging in colorectal cancer. This study aims to analyze clinical factors associated with lymph node retrieval in laparoscopic colorectal cancer surgery and to explore strategies that may enhance yield.</p><p><strong>Methods: </strong>We conducted a retrospective review of clinical, pathological, and surgical data from patients who underwent laparoscopic colorectal cancer resection between July 2019 and July 2024 at our institution. Patients were stratified by lymph node yield into 2 groups: <12 nodes (reduced yield) and ≥12 nodes (control). Univariate analyses were used to identify factors potentially affecting lymph node yield, and multivariate logistic regression was performed to determine independent risk factors for reduced yield.</p><p><strong>Results: </strong>A total of 639 patients (305 with rectal cancer and 334 with colon cancer) were included. Univariate analysis identified age (P=0.039), sex (P=0.029), neoadjuvant therapy (P<0.001), tumor location (P<0.001), invasion depth (P<0.001), lymphovascular invasion (P=0.028), and station-specific lymph node submission (P<0.001) as influential factors. Multivariate analysis revealed that preoperative neoadjuvant therapy, tumor location (non-right colon), shallow invasion depth (T1-T2), and lack of station-specific submission independently contributed to reduced lymph node yield (all P<0.05).</p><p><strong>Conclusion: </strong>This study highlights preoperative neoadjuvant therapy, tumor location, and invasion depth (T stage) as independent factors associated with reduced lymph node yield in laparoscopic colorectal cancer surgery. However, station-specific lymph node submission significantly increases yield and may help address inadequate retrieval. These findings suggest both predictive and interventional strategies to optimize lymph node harvest after surgery.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":"42 2","pages":"216-225"},"PeriodicalIF":2.2,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13254662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148209793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}