Annals of Coloproctology最新文献

{"title":"Total neoadjuvant therapy in rectal cancer: a network meta-analysis of randomized trials.","authors":"Sergey Sychev,&nbsp;Aleksey Ponomarenko,&nbsp;Stanislav Chernyshov,&nbsp;Mikhail Alekseev,&nbsp;Zaman Mamedli,&nbsp;Dmitriy Kuzmichev,&nbsp;Andrey Polynovskiy,&nbsp;Evgeny Rybakov","doi":"10.3393/ac.2022.00920.0131","DOIUrl":"https://doi.org/10.3393/ac.2022.00920.0131","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the efficacy of total neoadjuvant therapy (TNT) for rectal carcinoma in comparison with conventional chemoradiotherapy (CRT).</p><p><strong>Methods: </strong>A systematic review was performed according to the PRISMA guidelines. A Bayesian network meta-analysis was done using NetMetaXL and WinBUGS. This study was registered in PROSPERO on March 3, 2022 (No. CRD-42022307867).</p><p><strong>Results: </strong>Outcomes of 2,719 patients from 10 randomized trials between 2010 and 2022 were selected. Of these 1,191 (44%) had conventional long-course CRT (50-54 Gy) and capecitabine, 506 (18%) had induction chemotherapy followed by CRT (50-54 Gy) and capecitabine (iTNT), 230 (9%) had long-course CRT (50-54 Gy) followed by consolidation chemotherapy (cTNT), and 792 (29%) undergone modified short-course radiotherapy (25 Gy) with subsequent chemotherapy (mTNT). Total pathologic complete response (pCR) was 20% in the iTNT group, 21% in the mTNT group, 22% in the cTNT group, and 12% in the CRT group. Statistically significant difference in pCR rates was detected when comparing iTNT with CRT (odds ratio [OR], 1.76; 95% credible interval [CrI], 1.06-2.8), mTNT with CRT (OR, 1.90; 95% CrI, 1.25-2.74), and cTNT with CRT groups (OR, 2.54; 95% CrI, 1.26-5.08). No differences were found in R0 resection rates. No significant difference was found in long-term outcomes.</p><p><strong>Conclusion: </strong>The early administration of systemic chemotherapy in the TNT regimen has improved short-term outcomes, though long-term results are underreported. Randomized trials with survival as the endpoint are necessary to evaluate the possible advantages of TNT modes.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5f/64/ac-2022-00920-0131.PMC10475801.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10213441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic prediction of colorectal cancer using the C-reactive protein to albumin ratio: the importance of inflammatory biomarkers and their association with long-term outcomes.","authors":"Chul Seung Lee","doi":"10.3393/ac.2023.00486.0069","DOIUrl":"https://doi.org/10.3393/ac.2023.00486.0069","url":null,"abstract":"ing cause of death in Korea [1]. The standard therapy recommended for high-risk stage II and III patients is oxaliplatin-based adjuvant chemotherapy combined with fluoropyrimidine. This treatment regimen has significantly enhanced both overall survival and disease-free survival rates. However, outcomes can vary greatly among patients with the same disease stage [2]. Most patients who experience recurrence ultimately succumb to distant metastases [2, 3]. Therefore, considerable efforts have been made to investigate risk factors linked to distant metastasis in colorectal cancer, as well as to develop strategies for its prevention and management to improve oncological outcomes. Systemic inflammation has been identified as a key factor affecting the prognosis of colorectal cancer, prompting extensive research into various biomarkers [4–7]. Inflammatory indicators, such as the Glasgow Prognostic Score, neutrophil to lymphocyte ratio, and lymphocyte to monocyte ratio, have been extensively studied [6, 7]. More recently, the C-reactive protein to albumin ratio (CAR) has been reported to be a useful predictor of the prognosis of CRC. Kataoka et al. [8] found a distinct association between CAR on postoperative day (POD) 7 and prognosis. They proposed that CAR on POD 7 plays a significant role in the metastatic process of cancer. Even when patients undergo scheduled adjuvant chemoPrognostic prediction of colorectal cancer using the C-reactive protein to albumin ratio: the importance of inflammatory biomarkers and their association with long-term outcomes","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7c/bb/ac-2023-00486-0069.PMC10475799.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10162522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simple mucopexy and hemorrhoidal arterial ligation with and without Doppler guide: a randomized clinical trial for short-term outcome.","authors":"Mahdi Alemrajabi,&nbsp;Abolfazl Akbari,&nbsp;Sara Sohrabi,&nbsp;Mohammad Rezazadehkermani,&nbsp;Mohammad Moradi,&nbsp;Shahram Agah,&nbsp;Mohsen Masoodi","doi":"10.3393/ac.2022.00017.0002","DOIUrl":"https://doi.org/10.3393/ac.2022.00017.0002","url":null,"abstract":"<p><strong>Purpose: </strong>Hemorrhoids are the most common benign anorectal diseases. Mucopexy strengthens the anal canal mucosa, which can be performed alone or in combination with Doppler-guided hemorrhoidal artery ligation (DG-HAL). In this study, we compared the postoperative complications between simple mucopexy plus HAL with and without a Doppler guide.</p><p><strong>Methods: </strong>This study was performed as a single-blinded randomized clinical trial. Patients referred to a tertiary colorectal referral clinic with grades 3 and 4 hemorrhoids who were candidates for surgical intervention entered the study. Thirty-six patients were randomly divided into 2 groups. Group A including 18 patients underwent mucopexy and DG-HAL and the other 18 patients (group B) underwent standard mucopexy and HAL without a Doppler guide. Postoperative pain score and the duration of oral analgesic consumption were recorded. Additionally, postoperative symptoms and complications were recorded and compared between the 2 methods.</p><p><strong>Results: </strong>There was no significant difference between the 2 groups in terms of pain score and the duration of postoperative analgesic consumption as well as the incidence of postoperative complications. Besides, the primary grade of hemorrhoids was not significantly associated with recurrence, but there was a significant association between body mass index and Wexner score (WS) with recurrence. The mean WS of patients showed a significant decrease in both groups postoperatively. However, the rate of WS reduction was not remarkably different between the 2 groups.</p><p><strong>Conclusion: </strong>Simple mucopexy with blind HAL (without Doppler guide) might be considered for the treatment of grades 3 and 4 hemorrhoids effectively.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5e/43/ac-2022-00017-0002.PMC10475797.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10212389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report of a colouterine fistula treatment: when the patient chooses the steeplechase.","authors":"Stefano Pontone,&nbsp;Pier Giorgio Nardis,&nbsp;Chiara Eberspacher,&nbsp;Domenico Mascagni","doi":"10.3393/ac.2021.00318.0045","DOIUrl":"https://doi.org/10.3393/ac.2021.00318.0045","url":null,"abstract":"<p><p>Colouterine fistula is a rare disease that is primarily treated using surgical approaches. Although invasive surgery is controversial in terms of techniques and results, minimally invasive endoscopic treatments have not been widely described. However, because it is rare for these fistulas to close spontaneously, surgical treatment is often mandatory. Appropriate management of colouterine fistula is complicated, especially when the patient refuses surgery. In this case study, we provide the first description of a minimally invasive endoscopic treatment of an iatrogenic colouterine fistula using a self-expandable metallic stent after an over-the-scope clip malposition.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3c/10/ac-2021-00318-0045.PMC10475798.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10153595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A fecalith mimicking a bladder calculus secondary to an appendicovesical fistula: a case report.","authors":"Mauricio Gonzalez-Urquijo,&nbsp;Andrea Romero-Davila,&nbsp;MaryCarmen Mendoza-Silva,&nbsp;Antonio Nassim Halun Treviño,&nbsp;Mario Rodarte-Shade,&nbsp;Gerardo Gil-Galindo","doi":"10.3393/ac.2020.00311.0044","DOIUrl":"https://doi.org/10.3393/ac.2020.00311.0044","url":null,"abstract":"<p><p>An appendicovesical fistula is defined as an abnormal communication between the appendix and the urinary bladder, with only a few cases reported in the literature. It is very challenging to make an early diagnosis, due to the inability of conventional imaging modalities to detect this unique pathology. The symptoms are often mild, and there are not any specific signs or symptoms that might suggest this type of anomalous communication. We report a case of a 27-year-old male patient who presented difficulty for initiating urination, dysuria, and persistent urinary tract infections. An abdominal x-ray showed a large calculus inside the bladder. A cystoscopy was performed, where the tip of the appendix was seen protruding inside the bladder with a large fecalith adhered to the bladder wall. An appendectomy and partial cystectomy with primary repair were auspiciously achieved. A review of the literature is also presented.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/10/14/ac-2020-00311-0044.PMC10475804.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10156851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Newer procedures need to demonstrate efficacy in high complex anal fistulas.","authors":"Pankaj Garg","doi":"10.3393/ac.2022.01109.0158","DOIUrl":"https://doi.org/10.3393/ac.2022.01109.0158","url":null,"abstract":"I read with great interest the article by Lalhruaizela [1] highlighting his experience with endofistula laser ablation (EFLA) in anal fistulas. The author reported a primary success rate of 67.7% and a secondary (overall) success rate of 80% in a cohort of 31 anal fistula patients. However, there are a couple of questions and pertinent points that merit discussion according to our experiences. The author included only primary, simple low uncomplicated fistulas in the study and excluded high complex fistulas [1]. However, it was not precisely defined which fistulas were categorized as simple and which ones as complex. One patient with a suprasphincteric fistula was also included in the study. Suprasphincteric fistulas are high complex fistulas and are categorized as grade III by Garg [2] and grade V by the St. James’s University Hospital [2] and Garg classifications [2, 3]. Low fistulas are defined as those involving less than one-third of the external anal sphincter [2]. It is an established fact that fistulotomy is the gold standard for managing low simple fistulas [3]. A success rate of 98% to 100% can be achieved in low fistulas with minimal risk to continence [3]. Therefore, the management of low simple fistulas is almost a settled issue. However, fistulotomy is contraindicated in high fistulas (fistulas involving more than onethird of the external anal sphincter) due to the high risk of incontinence [3]. Therefore, what is urgently needed is to find a sphincter-saving procedure in high fistulas that would not cause a significant deterioration in continence. Several new sphincter-saving procedures have been advocated Newer procedures need to demonstrate efficacy in high complex anal fistulas","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f9/c0/ac-2022-01109-0158.PMC10475806.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10529275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body composition index obtained by using a bioelectrical impedance analysis device can be a predictor of prolonged operative time in patients undergoing minimally invasive colorectal surgery.","authors":"Ho Seung Kim,&nbsp;Kwang Ho Kim,&nbsp;Gyoung Tae Noh,&nbsp;Ryung-Ah Lee,&nbsp;Soon Sup Chung","doi":"10.3393/ac.2022.00262.0037","DOIUrl":"https://doi.org/10.3393/ac.2022.00262.0037","url":null,"abstract":"<p><strong>Purpose: </strong>Obesity has been known to contribute to technical difficulties in surgery. Until now, body mass index (BMI) has been used to measure obesity. However, there are reports that BMI does not always correspond to the visceral fat. Recently, bioelectrical impedance analysis (BIA) has been used for body composition analysis. This study aimed to evaluate the usefulness of the body composition index obtained using a BIA device in predicting short-term postoperative outcomes.</p><p><strong>Methods: </strong>Data of patients who underwent elective major colorectal surgery using minimally invasive techniques were reviewed retrospectively. Body composition status was recorded using a commercial BIA device the day before surgery. The relationship between BMI, body composition index, and short-term postoperative outcomes, including operative time, was analyzed.</p><p><strong>Results: </strong>Sixty-six patients were enrolled in this study. In the correlation analysis, positive correlation was observed between BMI and body composition index. BMI and body composition index were not associated with short-term postoperative outcomes. Percent body fat (odds ratio, 4.226; 95% confidence interval [CI], 1.064-16.780; P=0.041) was found to be a statistically significant factor of prolonged operative time in the multivariate analysis. Correlation analysis showed that body fat mass was related to prolonged operative time (correlation coefficients, 0.245; P=0.048). In the area under curve analysis, body fat mass showed a statistically significant predictive probability for prolonged operative time (body fat mass: area, 0.662; 95% CI, 0.531-0.764; P=0.024).</p><p><strong>Conclusion: </strong>The body composition index can be used as a predictive marker for prolonged operative time. Further studies are needed to determine its usefulness.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4b/ab/ac-2022-00262-0037.PMC10475805.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10158758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case report of an unexpected colonic polyp: cavernous hemangioma.","authors":"Miguel Mascarenhas,&nbsp;Rui Morais,&nbsp;Regina Teixeira,&nbsp;Guilherme Macedo","doi":"10.3393/ac.2020.00535.0076","DOIUrl":"https://doi.org/10.3393/ac.2020.00535.0076","url":null,"abstract":"<p><p>Cavernous hemangiomas of the colon are rare, benign vascular lesions, and the site most commonly affected is the rectosigmoid junction. Surgical treatment is recommended for large diffuse lesions but in the presence of pedunculated lesions, endoscopic resection should be preferred if possible. We report a case of a 65-year-old man referred for colonoscopy after positive fecal occult blood, that revealed at the level of the sigmoid colon, a wide base pedunculated polyp (35 mm) occupying more than half of the lumen, with the covering mucosa with a vinous appearance. In order to remove the lesion, a detachable snare was placed and polypectomy was performed. During the procedure, the detachable snare was cut with active bleeding, controlled after clip placement and diluted adrenaline injection. Afterwards, histology revealed a polypoid lesion with a hyperplastic mucosa and submucosal plane expanded by numerous thick-walled vessels in the context of a cavernous colonic hemangioma.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8b/b7/ac-2020-00535-0076.PMC10338163.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9786074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes of side-to-end versus end-to-end colorectal anastomosis in nonemergent sigmoid and rectal cancers: a randomized controlled clinical trial.","authors":"Tamer A A M Habeeb,&nbsp;Hatem Mohammad,&nbsp;Tamer Wasefy,&nbsp;Mohamed Ibrahim Mansour","doi":"10.3393/ac.2021.00906.0129","DOIUrl":"https://doi.org/10.3393/ac.2021.00906.0129","url":null,"abstract":"<p><strong>Purpose: </strong>The outcomes of open colorectal anastomosis of side-to-end versus end-to-end in nonemergent sigmoid and rectal cancer surgery in adults were compared.</p><p><strong>Methods: </strong>A randomized controlled trial on individuals with sigmoid and rectal cancers was conducted between September 2016 and September 2018.</p><p><strong>Results: </strong>The mean age was 62.58±12.3 years in the side-to-end anastomotic (SEA) group and 61.03±13.98 years in the end-to-end anastomotic (EEA) group. Except for the operative time, intraoperative data revealed no significant differences between the studied groups, and the SEA group revealed that the mean anastomotic time was significantly shorter. Perioperative blood loss, length of stay, reoperation, inpatient death, infection, and bleeding were significantly associated with leakage. There is a statistically significant change regarding the range of bowel frequency in the EEA group only (P=0.04). There is a statistically significant difference regarding incontinence for flatus in the SEA group only (P≤0.001). A statistically significant change in both groups regards incontinence for liquid stools (P≤0.001) and clustering of stools (P≤0.001 and P=0.043). The quality of life in the SEA group significantly dropped at 6 months and then returned to baseline as regards to physical well-being (PWB), functional well-being (FWB), and colorectal cancer symptoms (CCS) with no difference as regards SWB and EWB, while in the EEA group, the exact change happened only as regard PWB and FWB, but SWB and CCS percentage did not return to baseline.</p><p><strong>Conclusion: </strong>The SEA group offers a safe alternative approach to the EEA group.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e5/81/ac-2021-00906-0129.PMC10338166.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9774923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of preoperative chemoradiotherapy in patients with cT2N0 distal rectal cancer.","authors":"Min Young Park,&nbsp;Chang Sik Yu,&nbsp;Tae Won Kim,&nbsp;Jong Hoon Kim,&nbsp;Jin-Hong Park,&nbsp;Jong Lyul Lee,&nbsp;Yong Sik Yoon,&nbsp;In Ja Park,&nbsp;Seok-Byung Lim,&nbsp;Jin Cheon Kim","doi":"10.3393/ac.2022.00066.0009","DOIUrl":"https://doi.org/10.3393/ac.2022.00066.0009","url":null,"abstract":"<p><strong>Purpose: </strong>This study was designed to determine the feasibility of preoperative chemoradiotherapy (PCRT) in patients with clinical T2N0 distal rectal cancer.</p><p><strong>Methods: </strong>Patients who underwent surgery for clinical T2N0 distal rectal cancer between January 2008 and December 2016 were included. Patients were divided into PCRT and non-PCRT groups. Non-PCRT patients underwent radical resection or local excision (LE) according to the surgeon's decision, and PCRT patients underwent surgery according to the response to PCRT. Patients received 50.0 to 50.4 gray of preoperative radiotherapy with concurrent chemotherapy.</p><p><strong>Results: </strong>Of 127 patients enrolled, 46 underwent PCRT and 81 did not. The mean distance of lesions from the anal verge was lower in the PCRT group (P=0.004). The most frequent operation was transanal excision and ultralow anterior resection in the PCRT and non-PCRT groups, respectively. Of the 46 patients who underwent PCRT, 21 (45.7%) achieved pathologic complete response, including 15 of the 24 (62.5%) who underwent LE. Rectal sparing rate was significantly higher in the PCRT group (11.1% vs. 52.2%, P<0.001). There were no significant differences in 3- and 5-year overall survival and recurrence-free survival regardless of PCRT or surgical procedures.</p><p><strong>Conclusion: </strong>PCRT in clinical T2N0 distal rectal cancer patients increased the rectal sparing rate via LE and showed acceptable oncologic outcomes. PCRT may be a feasible therapeutic option to avoid abdominoperineal resection in clinical T2N0 distal rectal cancer.</p>","PeriodicalId":8267,"journal":{"name":"Annals of Coloproctology","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/74/41/ac-2022-00066-0009.PMC10338167.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9781596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}