Annals of Dermatology最新文献_第2页

Meconopsis quintuplinervia Regel Improves Cutibacterium acnes-Induced Inflammatory Responses in a Mouse Ear Edema Model and Suppresses Pro-Inflammatory Chemokine Production via the MAPK and NF-κB Pathways in RAW264.7 Cells. Meconopsis quintuplinervia Regel 可改善小鼠耳部水肿模型中痤疮杆菌诱发的炎症反应，并通过 RAW264.7 细胞中的 MAPK 和 NF-κB 通路抑制促炎性趋化因子的产生。

IF 1.6 4区医学

Annals of Dermatology Pub Date : 2023-12-13 DOI: 10.5021/ad.22.206

Liying Gao, Mi Xie, Xiayu Zhang, Zhenhan Qiu, Zhen Pu, Shan Huang, Bin Li

引用次数: 0

Effects of Poly-L-Lactic Acid on Adipogenesis and Collagen Gene Expression in Cultured Adipocytes Irradiated with Ultraviolet B Rays. 聚-L-乳酸对经紫外线 B 线照射的培养脂肪细胞中脂肪生成和胶原蛋白基因表达的影响

IF 1.6 4区医学

Annals of Dermatology Pub Date : 2023-12-13 DOI: 10.5021/ad.22.177

Hyun-Wook Kim, Yun-A Jung, Ji-Min Yun, Yura Kim, Sung-Ae Kim, Seong-Il Suh, Young-Wook Ryoo

引用次数: 0

Dermoscopic and Histopathologic Analysis of the Correlation between the Pigmentation of Basal Cell Carcinoma and Tumor Aggressiveness. 皮肤镜和组织病理学分析基底细胞癌色素沉着与肿瘤侵袭性之间的相关性

IF 1.6 4区医学

Annals of Dermatology Pub Date : 2023-12-13 DOI: 10.5021/ad.23.046

Jong Heon Park, Ju Young Jo, Hyunwoo Park, Il-Hwan Kim

引用次数: 0

Dermal Fillers in the Treatment of Acne Scars: A Review. 皮肤填充剂治疗痤疮疤痕：综述。

IF 1.6 4区医学

Annals of Dermatology Pub Date : 2023-12-13 DOI: 10.5021/ad.22.230

Eman Almukhadeb, Faisal Binkhonain, Abeer Alkahtani, Sarah Alhunaif, Feras Altukhaim, Khalid Alekrish

引用次数: 0

Pigmented Fungiform Papillae of the Tongue: A Single-center Experience and Review of Literature. 舌头上的色素性真菌乳头：单中心经验与文献综述

IF 1.5 4区医学

Annals of Dermatology Pub Date : 2023-08-01 DOI: 10.5021/ad.22.192

Jungsoo Lee, Jin-Su Lee, Sung-Min Park, Kihyuk Shin, Hyun-Chang Ko, Byung-Soo Kim, Moon-Bum Kim, Hoon-Soo Kim

{"title":"Pigmented Fungiform Papillae of the Tongue: A Single-center Experience and Review of Literature.","authors":"Jungsoo Lee, Jin-Su Lee, Sung-Min Park, Kihyuk Shin, Hyun-Chang Ko, Byung-Soo Kim, Moon-Bum Kim, Hoon-Soo Kim","doi":"10.5021/ad.22.192","DOIUrl":"10.5021/ad.22.192","url":null,"abstract":"Background: Pigmented fungiform papillae of the tongue (PFPT) is a rare benign pigmentary disorder of the tongue. In dark-skinned individuals, PFPT appears to be relatively common. However, limited data exist on PFPT in Korean patients.Objective: We aimed to investigate the clinical characteristics of PFPT in Korean patients.Methods: Patients diagnosed with PFPT between 1995 and 2021 at the Pusan National University Hospital were included. Clinical characteristics of PFPT, dermoscopic findings, and comorbidities were reviewed.Results: A total of 19 patients diagnosed with PFPT were enrolled. The male to female ratio was approximately 1:5. The mean age at diagnosis was 41.1 years (range, 8~67 years). According to Holzwanger's classification, Type I was the most common (89.5%). PFPT was commonly concomitant with pigmentary disorders, including mucosal melanotic macules, Laugier-Hunziker syndrome, melasma, and melanonychia (6/19, 31.6%). Preceding oral infection or inflammatory lesions were found in four patients (21.1%), and systemic diseases and infectious diseases existed in two patients (10.5%). Dermoscopic examination was performed in seven patients; pigmented border with dichotomized vessels (rose petal pattern, 71.4%) and diffuse pigmentation (cobblestone pattern, 71.4%) were common findings.Conclusion: Our study shows PFPT can coexist with pigmentary disorders. Concomitant pigmentary disorder shows an association with sex hormone or susceptibility to abnormal pigmentation may be a possible cause of PFPT.","PeriodicalId":8233,"journal":{"name":"Annals of Dermatology","volume":"35 4","pages":"266-274"},"PeriodicalIF":1.5,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5a/d6/ad-35-266.PMC10407334.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9964661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of the Effects of Bathing and the Dry Technique on the Skin Condition of Early Neonates: A Prospective Observational Study. 沐浴法与干法对早期新生儿皮肤状况影响的前瞻性观察研究。

IF 1.6 4区医学

Annals of Dermatology Pub Date : 2023-08-01 DOI: 10.5021/ad.22.098

Sachi Higuchi, Seiichi Yoshida, Takeo Minematsu, Yutaka Hatano, Akifumi Notsu, Takamichi Ichinose

{"title":"Comparison of the Effects of Bathing and the Dry Technique on the Skin Condition of Early Neonates: A Prospective Observational Study.","authors":"Sachi Higuchi, Seiichi Yoshida, Takeo Minematsu, Yutaka Hatano, Akifumi Notsu, Takamichi Ichinose","doi":"10.5021/ad.22.098","DOIUrl":"https://doi.org/10.5021/ad.22.098","url":null,"abstract":"Background: In Japan, neonates have typically been bathed in a bathtub immediately after birth because bathing is a custom for cleansing impurities. However, dry technique has been introduced into many institutions since 2000. There is little scientific evidence on the benefit or harmfulness of either method to neonatal skin, and consequently, opinion remains split on which method is superior.Objective: The purpose of the present study was to determine whether bathing or the dry technique of cleaning is better in maintaining skin health in the early neonatal period.Methods: Transepidermal water loss (TEWL) and skin pH, considered an index of skin barrier function, were measured in each group. Tumor necrosis factor (TNF)-alpha and interleukin (IL)-6, which are inflammatory cytokines released by keratinocytes, were measured by skin blotting.Results: TEWL and skin pH of neonates were lower with the dry technique than with bathing. The expression level of IL-6 and TNF-α in chest skin of neonates was higher with bathing than with the dry technique.Conclusion: These results suggest that the dry technique may maintain skin health better than bathing in the early neonatal period.","PeriodicalId":8233,"journal":{"name":"Annals of Dermatology","volume":"35 4","pages":"256-265"},"PeriodicalIF":1.6,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2c/60/ad-35-256.PMC10407340.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10318917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Immune Microenvironment in Basal Cell Carcinoma. 基底细胞癌的免疫微环境。

IF 1.6 4区医学

Annals of Dermatology Pub Date : 2023-08-01 DOI: 10.5021/ad.22.042

Catherine Zilberg, James Guy Lyons, Ruta Gupta, Diona Lee Damian

引用次数: 0

Relationship between Illness Behavior and Hair Loss Pattern According to the Basic and Specific (BASP) Classification. 基于BASP分类的疾病行为与脱发模式的关系

IF 1.6 4区医学

Annals of Dermatology Pub Date : 2023-08-01 DOI: 10.5021/ad.21.085

Ju Yeong Lee, Chunk Hyeok Kim, Won-Soo Lee

引用次数: 0

A Pilot Genome-Wide Association Study Identifies Novel Markers of Metabolic Syndrome in Patients with Psoriasis. 一项试点全基因组关联研究确定了银屑病患者代谢综合征的新标志物。

IF 1.6 4区医学

Annals of Dermatology Pub Date : 2023-08-01 DOI: 10.5021/ad.22.196

Seung-Min Oh, Su-Kang Kim, Hye-Jin Ahn, Ki-Heon Jeong

{"title":"A Pilot Genome-Wide Association Study Identifies Novel Markers of Metabolic Syndrome in Patients with Psoriasis.","authors":"Seung-Min Oh, Su-Kang Kim, Hye-Jin Ahn, Ki-Heon Jeong","doi":"10.5021/ad.22.196","DOIUrl":"https://doi.org/10.5021/ad.22.196","url":null,"abstract":"Background: Recent studies have reported that psoriasis is associated with the development of metabolic syndrome. Genome-wide association studies have been used to discover gene variant markers that occur frequently in case group in relation to specific diseases.Objective: The aim of the present study was to investigate the variants of specific genes involved in metabolic syndrome associated with psoriasis.Methods: A total of 95 psoriasis patients were recruited and divided into two groups: one with metabolic syndrome (38 patients) and the other without (57 patients). After genotyping, imputation, and quality checking, the association between the several single nucleotide polymorphisms and metabolic syndrome in psoriasis was tested, followed by gene set enrichment analysis.Results: We found 76 gene polymorphisms that conferred an increased risk for metabolic syndrome in patients with psoriasis. Four single nucleotide polymorphisms (rs17154774 of FRMD4A, rs77498336 of GPR116, rs75949580 and rs187682251 of MAPK4) showed the strongest association between metabolic syndrome and psoriasis. The epidermal growth factor receptor protein was located at the center of the protein interactions for the gene polymorphisms.Conclusion: This study identified several previously unknown polymorphisms associated with metabolic syndrome in psoriasis. These results highlight the potential for future genetic studies to elucidate the development, and ultimately prevent the onset, of metabolic syndrome in patients with psoriasis.","PeriodicalId":8233,"journal":{"name":"Annals of Dermatology","volume":"35 4","pages":"285-292"},"PeriodicalIF":1.6,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b6/fc/ad-35-285.PMC10407332.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10018871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effect of Janus Kinase 3 Inhibitor on Sebaceous Gland Regeneration during Skin Wound Healing. Janus激酶3抑制剂对皮肤创面愈合中皮脂腺再生的影响。

IF 1.6 4区医学

Annals of Dermatology Pub Date : 2023-08-01 DOI: 10.5021/ad.22.204

Won Tae Jo, A Young Kim, Hyun Goo Woo, Hae Jun Song, Eun Joo Baik

{"title":"Effect of Janus Kinase 3 Inhibitor on Sebaceous Gland Regeneration during Skin Wound Healing.","authors":"Won Tae Jo, A Young Kim, Hyun Goo Woo, Hae Jun Song, Eun Joo Baik","doi":"10.5021/ad.22.204","DOIUrl":"https://doi.org/10.5021/ad.22.204","url":null,"abstract":"Background: Janus kinase (Jak) 3 has recently been shown as a beneficial target for the treatment of chronic inflammatory diseases, such as psoriasis and alopecia areata. The role of Jak3 in tissue repair and remodeling is emerging.Objective: This study aimed to investigate the role of Jak3 signaling in the remodeling of the sebaceous gland (SG) during skin wound repair, and the development of in vitro SGs.Methods: Mouse skin tissue (ICR mouse) was obtained from the recovered skin eight days after a 4 mm biopsy punch wound. To observe the role of Jak3, the selective inhibitors WHI-p131 and PF06651600 was administered. Formation of in vitro SG was examined using primary sebocyte cultures obtained postnatally from 3-day-old mice.Results: The data showed that SGs showed highly positive signals with anti-isolectin B4, which also used for detection of angiogenetic vessels and the basal epidermis. Isolectin B4 could be a good indicator of SGs. The Jak3 inhibitors significantly reduced the area and volume of SG remodeling with reduced expression of p-Jak3. In addition, the area of cultured intact SG in vitro was significantly decreased in a concentration-dependent manner by Jak3 inhibition.Conclusion: These data showed that Jak3 signaling is a potent regulator to develop SGs. Jak3 inhibition did not decrease the number of sebocytes in SGs but decreased the area and volume of SG remodeling. Therefore, Jak3 inhibition may be a potential target for the treatment of SG hyperplasia and associated skin diseases.","PeriodicalId":8233,"journal":{"name":"Annals of Dermatology","volume":"35 4","pages":"275-284"},"PeriodicalIF":1.6,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7e/60/ad-35-275.PMC10407337.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10337007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0