Archives internationales de physiologie et de biochimie最新文献

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The influence of lipogenic and lipolytic conditions on the pentose phosphate pathway dehydrogenases in rat-kidney-cortex. 脂质生成和脂质分解条件对大鼠肾皮质戊糖磷酸途径脱氢酶的影响。
Archives internationales de physiologie et de biochimie Pub Date : 1990-10-01 DOI: 10.3109/13813459009113988
J Peragon, F Aranda, L Garcia-Salguero, J B Barroso, M V Amores, J A Lupiañez
{"title":"The influence of lipogenic and lipolytic conditions on the pentose phosphate pathway dehydrogenases in rat-kidney-cortex.","authors":"J Peragon,&nbsp;F Aranda,&nbsp;L Garcia-Salguero,&nbsp;J B Barroso,&nbsp;M V Amores,&nbsp;J A Lupiañez","doi":"10.3109/13813459009113988","DOIUrl":"https://doi.org/10.3109/13813459009113988","url":null,"abstract":"<p><p>The effects of various lipogenic and antilipogenic states on the activities of rat-kidney cortex glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase have been studied. These conditions are related to the long-term administration of different diets, such as high-carbohydrate (80%) and high-fat (23%), and also to a state of fast. Contrary to what happens in liver cells and kidney cortex during a high protein diet administration, none of these nutritional conditions produced significant changes in the kinetics of either kidney hexose monophosphate dehydrogenases.</p>","PeriodicalId":8170,"journal":{"name":"Archives internationales de physiologie et de biochimie","volume":"98 5","pages":"283-9"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/13813459009113988","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12873563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Tropomyosin from the striated muscles of carp (Cyprinus carpio) and of icefish (Channichthys rhinoceratus). 原肌球蛋白来自鲤鱼(Cyprinus carpio)和冰鱼(Channichthys rhinoceratus)的横纹肌。
Archives internationales de physiologie et de biochimie Pub Date : 1990-10-01 DOI: 10.3109/13813459009113990
G Feller, J D'Haese, C Gerday
{"title":"Tropomyosin from the striated muscles of carp (Cyprinus carpio) and of icefish (Channichthys rhinoceratus).","authors":"G Feller,&nbsp;J D'Haese,&nbsp;C Gerday","doi":"10.3109/13813459009113990","DOIUrl":"https://doi.org/10.3109/13813459009113990","url":null,"abstract":"<p><p>Tropomyosin of fast-twitch, slow-twitch and cardiac muscles of carp and icefish has been isolated by hydroxyapatite chromatography. The subunit distribution has been investigated by polyacrylamide gel electrophoresis and by peptide mapping. The purified skeletal muscle tropomyosins all belong to the alpha family and differ from higher vertebrate tropomyosin by the lack of beta subunits. Specific alpha isotypes are however encountered in fast-twitch fibres (alpha w subunit) and slow-twitch or intermediate (pink) fibres (alpha and alpha w subunits). The amino acid compositions and the paracrystals formed by the carp alpha w alpha w and alpha alpha w tropomyosins do not differ markedly from that of rabbit alpha alpha chains. They differ however by their capability to inhibit the ATPase activity of rabbit skeletal muscle acto-HMM system. A beta-like subunit is found in carp cardiac tropomyosin, in the proportion of 25% of the native protein, but not in icefish heart.</p>","PeriodicalId":8170,"journal":{"name":"Archives internationales de physiologie et de biochimie","volume":"98 5","pages":"297-305"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/13813459009113990","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12872918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Caerulein-induced acute pancreatitis in the rat. Pancreatic secretory response to cholecystokinin. 小蛋白诱导的大鼠急性胰腺炎。胰腺分泌对胆囊收缩素的反应。
Archives internationales de physiologie et de biochimie Pub Date : 1990-10-01 DOI: 10.3109/13813459009113983
J I San Román, I De Dios, M A Manso, J J Calvo, M A López
{"title":"Caerulein-induced acute pancreatitis in the rat. Pancreatic secretory response to cholecystokinin.","authors":"J I San Román,&nbsp;I De Dios,&nbsp;M A Manso,&nbsp;J J Calvo,&nbsp;M A López","doi":"10.3109/13813459009113983","DOIUrl":"https://doi.org/10.3109/13813459009113983","url":null,"abstract":"<p><p>The response of pancreatic exocrine secretion to cholecystokinin (CCK), has been studied in experimental acute pancreatitis induced in rats by supramaximal doses of caerulein. Several doses of caerulein were used (4, 20 and 40 micrograms/Kg) and each one was administered by four subcutaneous injections over 3 h at hourly intervals. Pancreatic juice was collected 9 h after the first injection. The caerulein-treated animals showed a statistically significant increase in serum amylase levels. Secretory activity of ductular cells remained unchanged in all the caerulein-treated animals, but total protein and amylase secretion decreased significantly at all the caerulein doses used, both in resting conditions and under stimulation with CCK (1.25 micrograms/Kg/h). Despite this the acinar cells of rats treated with the lowest dose of caerulein retained a certain degree of secretory function since amylase activity in pancreatic juice was greater than in other groups of rats treated with higher doses of caerulein. Moreover, the percentage of increase observed in total protein and amylase in response to CCK respect to basal secretion is similar to that of the untreated animals. At higher doses (20 and 40 micrograms/Kg) the secretory capacity in response to CCK was inhibited. Therefore CCK administration in slight acute pancreatitis could be used as a therapy since it favours the secretion of pancreatic enzymes at percentual levels similar to those of the controls.</p>","PeriodicalId":8170,"journal":{"name":"Archives internationales de physiologie et de biochimie","volume":"98 5","pages":"237-43"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/13813459009113983","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12873558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
[Inhibitory activity of allene cholesteryl derivatives on the biosynthesis of ecdysone]. [烯醛胆固醇衍生物对蜕皮激素生物合成的抑制作用]。
J P Roussel, A Burger, C Hetru
{"title":"[Inhibitory activity of allene cholesteryl derivatives on the biosynthesis of ecdysone].","authors":"J P Roussel,&nbsp;A Burger,&nbsp;C Hetru","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Prothoracic glands of the migratory locust Locusta migratoria during the postembryonnic development, are the biosynthetic source of ecdysone. The production of ecdysone by these glands in vitro has been used to evaluate the inhibitory activity of four cholesteryl derivatives with an allenic function on the side chain at C-22. These molecules were devised as potential inhibitors of hydroxylation at C-22 which is an obligate step in the biosynthesis of ecdysone. Three of the four molecules tested induce a marked depressory effect of the production of ecdysone. The effect of the compound with the higher activity was dose dependent and irreversible.</p>","PeriodicalId":8170,"journal":{"name":"Archives internationales de physiologie et de biochimie","volume":"98 5","pages":"253-9"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12873560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphometric and biochemical evaluation of rat prostate and seminal vesicle following chemical sympathectomy with guanethidine. 胍乙啶化学交感神经切除术后大鼠前列腺和精囊的形态计量学和生化评价。
Archives internationales de physiologie et de biochimie Pub Date : 1990-10-01 DOI: 10.3109/13813459009113981
T L Carvalho, S O Petenusci, A L Favaretto, W G Kempinas
{"title":"Morphometric and biochemical evaluation of rat prostate and seminal vesicle following chemical sympathectomy with guanethidine.","authors":"T L Carvalho,&nbsp;S O Petenusci,&nbsp;A L Favaretto,&nbsp;W G Kempinas","doi":"10.3109/13813459009113981","DOIUrl":"https://doi.org/10.3109/13813459009113981","url":null,"abstract":"<p><p>Selective chemical sympathectomy of the internal genital organs of adult male rats was undertaken by chronic treatment with low doses of guanethidine. Biochemical and morphometric methods revealed that removal of sympathetic innervation prevents fructose secretion in the prostate and seminal vesicle, in addition to promoting reduced efficiency of delivery by the latter.</p>","PeriodicalId":8170,"journal":{"name":"Archives internationales de physiologie et de biochimie","volume":"98 5","pages":"225-30"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/13813459009113981","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12873556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Effects of cadmium and mercury on Na(+)-K+, ATPase and uptake of 3H-dopamine in rat brain synaptosomes. 镉和汞对大鼠脑突触体Na(+)-K+、atp酶和3h -多巴胺摄取的影响。
Archives internationales de physiologie et de biochimie Pub Date : 1990-10-01 DOI: 10.3109/13813459009113989
B Rajanna, M Hobson, L Harris, L Ware, C S Chetty
{"title":"Effects of cadmium and mercury on Na(+)-K+, ATPase and uptake of 3H-dopamine in rat brain synaptosomes.","authors":"B Rajanna,&nbsp;M Hobson,&nbsp;L Harris,&nbsp;L Ware,&nbsp;C S Chetty","doi":"10.3109/13813459009113989","DOIUrl":"https://doi.org/10.3109/13813459009113989","url":null,"abstract":"<p><p>Effects in vivo of cadmium (Cd), mercury (Hg) and methylmercury (CH3Hg) on Na(+)-K+ ATPase and uptake of 3H-dopamine (DA) in rat brain synaptosomes were studied. These heavy metals significantly inhibited the Na(+)-K+ ATPase activity in a dose-dependent manner. Similarly, inhibition of DA uptake by synaptosomes was also observed in rats treated with these metals. Intraperitoneal route of metal administration was found to be more effective than per os treatment. Mercuric compounds compared to Cd elicited a higher inhibition of Na(+)-K+ ATPase and DA uptake in rat brain synaptosomes.</p>","PeriodicalId":8170,"journal":{"name":"Archives internationales de physiologie et de biochimie","volume":"98 5","pages":"291-6"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/13813459009113989","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12872917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 28
Changes in lipid parameters after intestinal resection or bypass in the rat. 大鼠肠切除或旁路手术后脂质参数的变化。
Archives internationales de physiologie et de biochimie Pub Date : 1990-10-01 DOI: 10.3109/13813459009113979
O Carreras, J C Carrillo, M L Murillo, M J Delgado
{"title":"Changes in lipid parameters after intestinal resection or bypass in the rat.","authors":"O Carreras,&nbsp;J C Carrillo,&nbsp;M L Murillo,&nbsp;M J Delgado","doi":"10.3109/13813459009113979","DOIUrl":"https://doi.org/10.3109/13813459009113979","url":null,"abstract":"<p><p>Intestinal resection, bypass and adaptative postoperative mechanisms developed as a consequence of that surgery, are considered good methods for improving knowledge of gastrointestinal physiology as well as possible effects that the intestine could have on the general metabolism. 50% jejunoileal bypass (BP), 50% proximal (PR) and distal (DR) intestinal resections were performed on rats to compare the influence of resected intestinal segments or bypassed loop localization could exert on different serum lipid parameters. One month after surgery significant increases in total serum cholesterol and cholesterol esters were found. There was no change in free cholesterol. A decrease in triglyceride was observed after distal and proximal resection but no changes after bypass. The cholesterol/phospholipid ratio was increased after resection and after bypass. It has been suggested that the changes in lipid metabolism produced after resections and bypass depend mainly on the loss of absorptive surface rather than on the position of the resected segment. The bypass loop may itself still exert some influence on lipoprotein metabolism, mainly on high density lipoprotein-cholesterol.</p>","PeriodicalId":8170,"journal":{"name":"Archives internationales de physiologie et de biochimie","volume":"98 5","pages":"209-15"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/13813459009113979","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12873024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vivo lipid and amino acid synthesis from 3-hydroxybutyrate in 15-day-old chick. 3-羟基丁酸在15日龄鸡体内脂质和氨基酸的合成。
Archives internationales de physiologie et de biochimie Pub Date : 1990-10-01 DOI: 10.3109/13813459009113980
G J Caamaño, M A Sanchez-Del-Castiool, A Linares, E Garcia-Peregrin
{"title":"In vivo lipid and amino acid synthesis from 3-hydroxybutyrate in 15-day-old chick.","authors":"G J Caamaño,&nbsp;M A Sanchez-Del-Castiool,&nbsp;A Linares,&nbsp;E Garcia-Peregrin","doi":"10.3109/13813459009113980","DOIUrl":"https://doi.org/10.3109/13813459009113980","url":null,"abstract":"<p><p>The in vivo utilization of 3-hydroxybutyrate for lipid and amino acid synthesis in liver, kidney and duodenal mucosa of overnight-starved 15-day-old chicks has been investigated. Lipid synthesis was higher in liver and duodenal mucosa than in kidney. Triglycerides were the main lipids synthesized from 3-hydroxybutyrate in liver and kidney, while in duodenal mucosa a higher amount of phospholipids was observed. This tissue utilized a high percentage of 3-hydroxybutyrate for the synthesis of free cholesterol, in agreement with the major role of intestine in body cholesterogenesis. All of the assayed tissues synthesized amino acids from 3-hydroxybutyrate at a similar rate, glutamate being always the main amino acid formed.</p>","PeriodicalId":8170,"journal":{"name":"Archives internationales de physiologie et de biochimie","volume":"98 5","pages":"217-24"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/13813459009113980","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12873555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Effect of partial starvation on in vitro spontaneous activity and glycogen levels of uterine smooth muscle from pregnant and non pregnant rats. 部分饥饿对妊娠和非妊娠大鼠子宫平滑肌自发活性和糖原水平的影响。
Archives internationales de physiologie et de biochimie Pub Date : 1990-10-01 DOI: 10.3109/13813459009113978
A B De Sterin, M López, J A Linares, A Goldraij
{"title":"Effect of partial starvation on in vitro spontaneous activity and glycogen levels of uterine smooth muscle from pregnant and non pregnant rats.","authors":"A B De Sterin,&nbsp;M López,&nbsp;J A Linares,&nbsp;A Goldraij","doi":"10.3109/13813459009113978","DOIUrl":"https://doi.org/10.3109/13813459009113978","url":null,"abstract":"<p><p>Effects of a restricted-diet (50% of the normal feeding) given during 14 days, on the isometric developed tension (IDT) of uterine horns isolated from pregnant and non pregnant (diestrous) rats, incubated in a KRB-medium without glucose, were explored. In 14 days-pregnant rats, dietary restriction did not alter the contractile activity with respect to normal-fed controls. Besides, levels of uterine glycogen, immediately after killing the animals or after 60 min incubation, remained unaltered. In advanced pregnancy partial starvation led to decay of spontaneous contractile activity after 60 min incubation. However, the considerable increment in the levels of tissue glycogen at 0 time was not modified, nor its decrease at the end of the in vivo experimental period. In non-pregnant rats, a reduced feeding did not alter the development of contractile tension, but exerted a pronounced effect on the glycogen levels: these were significantly lower than controls at 0 time but suffered no changes after 60 min on in vitro activity. Indomethacin appeared to have no effect on the spontaneous contractile activity of 14 days-pregnant rats. It significantly depressed contractility in 21 days-pregnant rats. Indomethacin did not modify the levels of glycogen in any of the experimental groups.</p>","PeriodicalId":8170,"journal":{"name":"Archives internationales de physiologie et de biochimie","volume":"98 5","pages":"201-7"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/13813459009113978","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12873022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Stimulation of carbohydrate metabolising enzymes by synthetic hypertrehalosemic peptides in thoracic musculature of the American cockroach, Periplaneta americana. 人工合成的高海藻酸肽对美洲大蠊胸肌碳水化合物代谢酶的刺激。
Archives internationales de physiologie et de biochimie Pub Date : 1990-10-01 DOI: 10.3109/13813459009113982
A P Jahagirdar, J W Gole, G L Orr, T Viswanatha, R G Downer
{"title":"Stimulation of carbohydrate metabolising enzymes by synthetic hypertrehalosemic peptides in thoracic musculature of the American cockroach, Periplaneta americana.","authors":"A P Jahagirdar,&nbsp;J W Gole,&nbsp;G L Orr,&nbsp;T Viswanatha,&nbsp;R G Downer","doi":"10.3109/13813459009113982","DOIUrl":"https://doi.org/10.3109/13813459009113982","url":null,"abstract":"<p><p>The ability of the synthetic hypertrehalosemic peptides, HT-I and HT-II, to influence the activities of glycogen phosphorylase, trehalase and hexokinase via elevation of Ca++ and cAMP levels was examined in thoracic musculature of the American cockroach, Periplaneta americana. The peptides effect dose- and time-dependent activation of phosphorylase, trehalase and hexokinase activities that occur concomitantly with elevated levels of intracellular calcium. In addition, HT-I increases the accumulation of cyclic AMP in muscle cells.</p>","PeriodicalId":8170,"journal":{"name":"Archives internationales de physiologie et de biochimie","volume":"98 5","pages":"231-5"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/13813459009113982","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12873557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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