Archives internationales de physiologie et de biochimie最新文献

Inotropic effect of hyperosmotic NaCl solutions on the isolated rat cardiac tissue. 高渗NaCl溶液对离体大鼠心脏组织的肌力作用。

Archives internationales de physiologie et de biochimie Pub Date : 1990-12-01 DOI: 10.3109/13813459009114001

J W Bassani, R A Bassani, M Rocha-e-Silva

引用次数: 4

[Modification of precocious evoked auditory potential amplitudes observed in tinnitus]. [耳鸣中观察到的早熟诱发听电位振幅的改变]。

Archives internationales de physiologie et de biochimie Pub Date : 1990-12-01

M C de Lavernhe-Lemaire, P Beutter

引用次数: 0

Purification and properties of liver arginase from teleostean fish Clarias batrachus (L.). 硬骨鱼肝精氨酸酶的纯化及性质研究。

Archives internationales de physiologie et de biochimie Pub Date : 1990-12-01 DOI: 10.3109/13813459009114003

R A Singh, S N Singh

引用次数: 9

[Alpha 2 adrenergic control of ventilation in the rat]. [α 2肾上腺素能对大鼠通气的控制]。

Archives internationales de physiologie et de biochimie Pub Date : 1990-12-01

D Lagneaux, J Lecomte

{"title":"[Alpha 2 adrenergic control of ventilation in the rat].","authors":"D Lagneaux, J Lecomte","doi":"","DOIUrl":"","url":null,"abstract":"In anaesthetized rats, ventilatory stimulation induced by phentolamine, an alpha sympatholytic agent, emphasizes the role of some adrenergic mechanisms in the control of the respiratory centres activity. Phentolamine (5 and 10 mg.kg-1, iv) stimulates ventilation after a 4 s latency, tidal volume and respiratory rate being both increased. A same response can also be provoked 10 min later, by a second identical iv administration, systemic blood pressure remaining then stable at its previous low level. Hyperventilation is also observed when phentolamine is injected in totally denervated rats, without any remaining baro- or chemosensitivity. Stimulation is thus due to a central activity in relation with the release of inhibitory influences. Phentolamine also causes hyperventilation after prazosin pretreatment indicating that the alpha 1 adrenergic blockade is not involved in the post-phentolamine stimulation. This is an alpha 2 adrenergic transmission dependent mechanism. Variation of the systemic blood pressure is not the main mechanism involved in the hyperventilation induced by phentolamine. Meanwhile, baroreceptor activity modulates the central response to the drug, as shown by the negative influence of the post-vasopressin arterial hypertension. Hyperoxia is also a modulating factor acting by two ways: an inhibition of the peripheral chemoreceptors activity is added to an arterial hypertension. On the other side, activation of these chemoreceptors by almitrine bismesilate increases the respiratory responses to phentolamine. As already shown by one of us (Lagneuax, 1986), phentolamine pretreated rats are more responsive to hypoxia and to almitrine. Moreover, these phentolamine pretreated rats are protected against cardiovascular collapses and against apnea, frequently observed during hypoxia without CO2 compensation.","PeriodicalId":8170,"journal":{"name":"Archives internationales de physiologie et de biochimie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1990-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12869866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Studies on human placental glutathione S-transferase. Multiplicity and mother age influence. 人胎盘谷胱甘肽s转移酶的研究。多样性和母亲年龄的影响。

Archives internationales de physiologie et de biochimie Pub Date : 1990-12-01 DOI: 10.3109/13813459009113994

A A Hunaiti, F I Irshaid

引用次数: 0

Glucocorticoids effects on exocrine pancreatic secretion in caerulein-induced acute pancreatitis in the rat. 糖皮质激素对小蛋白诱导的急性胰腺炎大鼠外分泌胰腺分泌的影响。

Archives internationales de physiologie et de biochimie Pub Date : 1990-12-01 DOI: 10.3109/13813459009113998

I de Dios, J I San Romàn, M Manso, J J Calvo, M A López

{"title":"Glucocorticoids effects on exocrine pancreatic secretion in caerulein-induced acute pancreatitis in the rat.","authors":"I de Dios, J I San Romàn, M Manso, J J Calvo, M A López","doi":"10.3109/13813459009113998","DOIUrl":"https://doi.org/10.3109/13813459009113998","url":null,"abstract":"The present work reports on exocrine pancreatic secretion in control rats, adrenalectomized rats and hydrocortisone-treated (10 mg/Kg/d) rats during 7 days, under normal conditions and after induction of acute pancreatitis with caerulein (20 micrograms/Kg) by 4 subcutaneous injections at hourly intervals. Pancreatic secretion was seen to be affected by the procedure of adrenalectomy, which led to a marked reduction in the secretion of proteins and amylase with respect to control values. This was probably due to the decrease occurring in the zymogen granules in the acinar cells of the exocrine pancreas, a phenomenon which also led to a decrease in pancreatic weight observed in these animals. Treatment with hydrocortisone induced a decrease in the secretion of proteins and amylase, as well as an increase in pancreatic weight. This agrees with the accepted hypothesis that large amounts glucocorticoids stimulate the synthesis and storage of proteins in the exocrine pancreas, reducing the secretory phase. The administration of high doses of caerulein under these conditions led to acute pancreatitis in the three groups of animals. This was paralleled by a dramatic decrease in protein and amylase secretion and by severe interstitial edema of the pancreas and by increases in serum amylase values. In the case of the animals treated previously with hydrocortisone, the latter were tripled with respect to the control animals. The conclusion is offered that since the storage of enzyme proteins is governed by glucocorticoids, which furthermore increase the sensitivity of the acinar cells to stimulation by secretagogues, the administration of these substances during the development of pancreatic lesions such as acute pancreatitis is highly compromising to the organism.","PeriodicalId":8170,"journal":{"name":"Archives internationales de physiologie et de biochimie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1990-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/13813459009113998","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12869889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 18

Interaction of some limbic structures which exert inhibitory effect on corticosterone secretion. 对皮质酮分泌有抑制作用的某些边缘结构的相互作用。

Archives internationales de physiologie et de biochimie Pub Date : 1990-12-01 DOI: 10.3109/13813459009113993

M Suárez, N I Perassi

引用次数: 4

Archives internationales de physiologie et de biochimie Pub Date : 1990-12-01 DOI: 10.3109/13813459009113995

S Dai

引用次数: 0

6-OHDA sympathectomy and exercise performance in the rat. 大鼠6-OHDA交感神经切除与运动表现。

Archives internationales de physiologie et de biochimie Pub Date : 1990-12-01 DOI: 10.3109/13813459009114005

F Trudeau, F Péronnet, L Béliveau, G Brisson

{"title":"6-OHDA sympathectomy and exercise performance in the rat.","authors":"F Trudeau, F Péronnet, L Béliveau, G Brisson","doi":"10.3109/13813459009114005","DOIUrl":"https://doi.org/10.3109/13813459009114005","url":null,"abstract":"6-hydroxydopamine (6-OHDA) was utilised for the study of the sympathetic nervous system in the resting rats and rats submitted to prolonged exercise. In order to reduce the acute physiological stress associated with an injection of 6-OHDA, beta-1 and alpha-1 adrenoceptors were blocked before the treatment leading to sympathectomy. Sympathectomised rats were divided in two groups: one sacrificed at rest, 24 hours after the treatment. The other group was sacrificed after a treadmill exercise to exhaustion. Running time to exhaustion was 36.0 +/- 4.5 min (mean +/- S.E.M.). This group ran significantly less than a control group brought to exhaustion in 73.7 +/- 10.0 min of exercise (P < 0.05). In order to make appropriate comparisons, another control group was run for 36 min. Some differences were observed between corresponding control and sympathectomized groups. At rest: 1) a lower plasma level of insulin, and 2) a higher plasma free fatty acid concentration were observed in sympathectomized rats. After 36 min of exercise: 1) a lower plasma concentration of norepinephrine, 2) no decrease of the plasma level of insulin, 3) no increase in the plasma glucagon concentration, and 4) a higher plasma glucose level were observed in sympathectomised rats when compared to control rats running for the same time. The lower plasma norepinephrine concentration in exercised sympathectomised rats suggests a lower sympathetic nervous activity in these animals than in control rats. The absence of a decrease of plasma insulin concentration and of an increase in glucagon can be attributed to this lower sympathetic activity in sympathectomised rats.(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":8170,"journal":{"name":"Archives internationales de physiologie et de biochimie","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1990-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/13813459009114005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12869864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Effects of angiotensin II and bilateral nephrectomy on norepinephrine catabolism in central nervous system. 血管紧张素II和双侧肾切除术对中枢神经系统去甲肾上腺素分解代谢的影响。

Archives internationales de physiologie et de biochimie Pub Date : 1990-12-01 DOI: 10.3109/13813459009113991

B E Fernandez, A E Dominguez

引用次数: 4