Journal of epilepsy最新文献

{"title":"","authors":"MD Steven C. Schachter","doi":"10.1016/S0896-6974(98)00019-X","DOIUrl":"10.1016/S0896-6974(98)00019-X","url":null,"abstract":"","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 6","pages":"Page 395"},"PeriodicalIF":0.0,"publicationDate":"1998-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(98)00019-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56294163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plasma homovanillic acid levels in temporal lobe epilepsy","authors":"Masato Fukuda ,&nbsp;Shin-Ichi Niwa ,&nbsp;Naoki Kumagai ,&nbsp;Shoji Nagakubo ,&nbsp;Ohiko Hashimoto ,&nbsp;Yukihiko Shirayama ,&nbsp;Akinobu Hata ,&nbsp;Tomomichi Kameyama ,&nbsp;Nobuo Anzai","doi":"10.1016/S0896-6974(98)00031-0","DOIUrl":"10.1016/S0896-6974(98)00031-0","url":null,"abstract":"<div><p>The role of the central dopaminergic system in temporal lobe epilepsy (TLE) was investigated through measurement of plasma homovanillic acid (pHVA) levels. Plasma HVA levels in 30 patients with TLE were determined and compared with those in 53 healthy control subjects. Their relationship with clinical variables was investigated. The mean pHVA level of the TLE patients (9.44 ± 3.44 ng/ml) was not significantly different from that of the normal control subjects (8.40 ± 2.67 ng/ml). The differences were also nonsignificant when the patients were divided into subgroups according to seizure frequency, the interval between blood sampling and the preceding or following seizure, paroxysm laterality in electroencephalogram, the number of antiepileptic drugs administered, manifestation of psychotic symptoms, or antipsychotic medication. The obtained results were interpreted as indicating dopaminergic activities are not involved in the pathophysiology of TLE or decreased dopaminergic activities in TLE patients are balanced with compensatorily increased dopaminergic activities for suppressing seizure generation.</p></div>","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 6","pages":"Pages 383-388"},"PeriodicalIF":0.0,"publicationDate":"1998-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(98)00031-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56294997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Febrile convulsions with focal sharp waves: A subgroup of benign partial epilepsies of childhood with multifactorial etiology","authors":"Hermann Doose ,&nbsp;Indra Tibow ,&nbsp;Eva Castiglione ,&nbsp;Bernd A. Neubauer","doi":"10.1016/S0896-6974(98)00043-7","DOIUrl":"10.1016/S0896-6974(98)00043-7","url":null,"abstract":"<div><p>Studies on the prognosis of febrile convulsions (FC) have scarcely considered the heterogeneity of FC and its relationship to the risk and the variable nature of subsequent afebrile seizures. Meaningful study of this issue requires a sample of FC children that is as homogeneous as possible. One such FC subgroup is children with focal sharp waves (shw) in the electroencephalogram (EEG) of a type characteristic of benign partial epilepsies (5%–10% of all FC children). Because the incidence of FC is elevated in children with benign partial epilepsy, the question arises whether these entities have certain pathogenetic mechanisms in common. Because only children with long-term follow-up are suitable for a study of these problems, the results obtained here allow no quantitative inferences regarding prognosis. Inclusion criteria were: 1) FC as the first seizure symptom; 2) focal shw characteristic of benign partial epilepsy; 3) first EEG before the fifth year of life; 4) at least four EEGs between the second and the eighth year of life. One-hundred and twenty-eight children were ascertained. Duration of follow-up ranged from 1–33 years. A positive family history of seizures was found in 34% of probands. The incidence of neonatal seizures was remarkably elevated (6%). Prolonged FC and FC with focal symptoms were significantly overrepresented. Long lasting FC (&gt;60 minutes) were associated with an occipital location of the shw. Fifty-nine children suffered subsequent afebrile seizures or epilepsy (selected material): idiophathic partial epilepsy (58%); idiopathic generalized epilepsy (12%); severe epilepsies (22%), usually with intractable complex partial seizures. The latter were clearly associated with FC lasting longer than 1 hour. In 91% of the patients generalized genetic EEG patterns like generalized spikes and waves, photoparoxysmal response, and theta rhythms were eventually detected. Among the shw findings, precentral (70%) and occipital (50%) foci predominated. Of 69 investigated siblings focal shw were detected in 14%. Febrile convulsions with focal shw represent a multifactorial disorder. The combined action of five factors seems relevant: 1) a hereditary impairment of brain maturation (represented by the shw-EEG trait); 2) a genetic anomaly expressed by photoparoxysmal response; 3) a genetic cortical hypersynchronization (theta rhythms); 4) the generalized spike wave abnormality; and 5) a genetic predisposition to FC that is represented by a high incidence of FC in relatives but is not expressed specifically in the EEG. Subsequent epilepsies are idiopathic (mostly partial) or the consequence of FC lasting more than 1 hour.</p></div>","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 6","pages":"Pages 341-354"},"PeriodicalIF":0.0,"publicationDate":"1998-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(98)00043-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56295876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"M.D. William J. Craven","doi":"10.1016/S0896-6974(97)00131-X","DOIUrl":"10.1016/S0896-6974(97)00131-X","url":null,"abstract":"","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 6","pages":"Pages 392-393"},"PeriodicalIF":0.0,"publicationDate":"1998-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(97)00131-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56291903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Another erroneous substitution of Lamisil® for Lamictal®","authors":"M.D. David G. Vossler","doi":"10.1016/S0896-6974(98)00025-5","DOIUrl":"10.1016/S0896-6974(98)00025-5","url":null,"abstract":"","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 6","pages":"Page 389"},"PeriodicalIF":0.0,"publicationDate":"1998-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(98)00025-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56294679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The epilepsy of the Emperor Theodore II Lascaris (1254–1258)","authors":"John Lascaratos ,&nbsp;Panaghiotis Vassilios Zis","doi":"10.1016/S0896-6974(98)00032-2","DOIUrl":"10.1016/S0896-6974(98)00032-2","url":null,"abstract":"<div><p>The study of contemporary historic sources affords us a clinical picture of the epilepsy of the Byzantine Emperor, Theodore II Lascaris (1254–1258). It appears that he suffered from an epileptic disorder of rather generalized tonic-clonic type (grand mal), which started to afflict him in all probability before the age of 30 years. Numerous incidents described by many historians of his entourage reveal that he also had serious behavior disorders that the famous Byzantine historian, George Pachymeres, directly attributed to his disease.</p></div>","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 6","pages":"Pages 296-300"},"PeriodicalIF":0.0,"publicationDate":"1998-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(98)00032-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56295020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nocturnal paroxysmal dystonia related to a prerolandic dysplasia","authors":"Santiago Arroyo ,&nbsp;Joan Santamaria ,&nbsp;Javier F. Setoain ,&nbsp;Francisco Lomeña ,&nbsp;Nuria Bargallo ,&nbsp;Eduardo Tolosa","doi":"10.1016/S0896-6974(98)00034-6","DOIUrl":"https://doi.org/10.1016/S0896-6974(98)00034-6","url":null,"abstract":"<div><p>Nocturnal paroxysmal dystonia (NPD) is a rare disorder characterized by attacks of short-lived dystonic, tonic, and choreoatetoid movements occurring mainly during sleep. Although seizures are believed to arise from the frontal lobe, their localization is, however, uncertain due to the lack of ictal clinical-electroencephalogram (EEG) correlations. We report two patients with episodes clinically compatible with NPD who also experienced occasional generalized tonic-clonic seizures in which there was a frontal (prerolandic) dysplasia detected by magnetic resonance imaging (MRI). In one patient interictal/ictal single photon emission computed tomography (SPECT) suggested that the seizure focus was over the area of dysplasia. Both patients support the notion that this type of epilepsy is a form of frontal lobe epilepsy, possibly originated in the prerolandic region.</p></div>","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 6","pages":"Pages 301-305"},"PeriodicalIF":0.0,"publicationDate":"1998-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(98)00034-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"109211801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"B.S. Matthew R. Sarkisian","doi":"10.1016/S0896-6974(98)00003-6","DOIUrl":"https://doi.org/10.1016/S0896-6974(98)00003-6","url":null,"abstract":"","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 6","pages":"Page 394"},"PeriodicalIF":0.0,"publicationDate":"1998-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(98)00003-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136848581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The lateralizing value of upper extremity movements in complex partial seizures of temporal lobe origin: A video-EEG study","authors":"Der-Jen Yen ,&nbsp;Hsiang-Yu Yu ,&nbsp;Chun-Hing Yiu ,&nbsp;Yang-Hsin Shih ,&nbsp;Shang-Yeong Kwan ,&nbsp;Ming-Shung Su","doi":"10.1016/S0896-6974(98)00028-0","DOIUrl":"10.1016/S0896-6974(98)00028-0","url":null,"abstract":"<div><p>We evaluated the lateralizing value of ictal upper extremity movements in temporal lobe epilepsy (TLE). Videotapes of 259 complex partial seizures from 83 patients who became seizure-free after anterior temporal lobectomy were retrospectively studied. Pathologic diagnosis included hippocampal sclerosis in 73 patients and “lesional” in 10 patients. Ictal upper extremity movements were arbitrarily classified into four categories including dystonic posturing, tonic posturing, hand automatisms, and immobility. Dystonic posturing occurred in 86 seizures (33.2%) from 29 patients (34.9%), which included 28 hippocampal sclerosis and only one (3.4%) lesional. In all seizures except one (98.8%), dystonic posturing was unilateral and contralateral to the seizure focus (<em>p</em> &lt; 0.001). Tonic posturing was observed in 64 seizures (24.7%), 48 unilateral and 16 bilateral, from 31 patients (37.3%). Tonic posturing did not lateralize the seizure focus (<em>p</em> = 0.477) or tend to secondarily generalize (<em>p</em> = 0.757). Unilateral or bilateral hand automatisms occurred in 188 seizures (72.6%) from 71 patients (85.5%). From 113 seizures with unilateral hand automatisms, 105 (92.9%) originated from the ipsilateral temporal lobe (<em>p</em> &lt; 0.001). Immobility of the upper extremities was found in 64 seizures (24.7%) and appeared not to lateralize.</p></div>","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 6","pages":"Pages 314-318"},"PeriodicalIF":0.0,"publicationDate":"1998-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(98)00028-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56294795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"M.D. Gregory L. Holmes","doi":"10.1016/S0896-6974(97)00128-X","DOIUrl":"10.1016/S0896-6974(97)00128-X","url":null,"abstract":"","PeriodicalId":81656,"journal":{"name":"Journal of epilepsy","volume":"11 6","pages":"Page 391"},"PeriodicalIF":0.0,"publicationDate":"1998-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0896-6974(97)00128-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56291867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}