Marilie D Gammon, Sharon K Sagiv, Sybil M Eng, Sumitra Shantakumar, Mia M Gaudet, Susan L Teitelbaum, Julie A Britton, Mary Beth Terry, Lian Wen Wang, Qiao Wang, Steve D Stellman, Jan Beyea, Maureen Hatch, Geoffrey C Kabat, Mary S Wolff, Bruce Levin, Alfred I Neugut, Regina M Santella
{"title":"Polycyclic aromatic hydrocarbon-DNA adducts and breast cancer: a pooled analysis.","authors":"Marilie D Gammon, Sharon K Sagiv, Sybil M Eng, Sumitra Shantakumar, Mia M Gaudet, Susan L Teitelbaum, Julie A Britton, Mary Beth Terry, Lian Wen Wang, Qiao Wang, Steve D Stellman, Jan Beyea, Maureen Hatch, Geoffrey C Kabat, Mary S Wolff, Bruce Levin, Alfred I Neugut, Regina M Santella","doi":"10.1080/00039890409602948","DOIUrl":"10.1080/00039890409602948","url":null,"abstract":"<p><p>Polycyclic aromatic hydrocarbon (PAH)-DNA adducts have been associated with breast cancer in several small studies. The authors' pooled analysis included 873 cases and 941 controls from a population-based case-control study. Competitive enzyme-linked immunosorbent assay in peripheral mononuclear cells was conducted in 2 rounds, and results were pooled on the basis of round-specific quantiles. The odds ratio for breast cancer was elevated in relation to detectable PAH-DNA adducts (1.29 as compared with nondetectable adduct levels; 95% confidence interval = 1.05, 1.58), but there was no apparent dose-response relationship with increasing quantiles. No consistent pattern emerged when the results were stratified by PAH sources (e.g., active cigarette smoking or PAH-containing foods), or when the cases were categorized by stage of disease or hormone receptor status. These data provide only modest support for an association between PAH-DNA adducts and breast cancer development.</p>","PeriodicalId":8155,"journal":{"name":"Archives of environmental health","volume":"59 12","pages":"640-9"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277204/pdf/nihms14256.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26099572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claire Ségala, David Poizeau, Françoise Neukirch, Michel Aubier, Jacques Samson, Pierre Gehanno
{"title":"Air pollution, passive smoking, and respiratory symptoms in adults.","authors":"Claire Ségala, David Poizeau, Françoise Neukirch, Michel Aubier, Jacques Samson, Pierre Gehanno","doi":"10.1080/00039890409602952","DOIUrl":"https://doi.org/10.1080/00039890409602952","url":null,"abstract":"<p><p>We studied the independent role of air pollution and passive smoking on respiratory symptoms and group of symptoms by following 46 adult nonsmokers for 14 wk. Outcomes included the incidence of 15 symptoms. After adjustment for passive smoking, clear rhinorrhea and cough were positively related to nitrogen dioxide (NO2), particles (PM10), and black smoke (BS); whereas headache was positively related to BS. Sneezing, sore throat, and cough were independently positively related to passive smoking. After adjustment for passive smoking, the occurrence of groups of symptoms and of the \"sore throat group\" were related to three pollutants. The occurrence of the \"possible infection group\" was positively related to BS. The occurrence of every group of symptoms was independently related to passive smoking. In conclusion, the prevailing levels of air pollution and passive smoking had independent effects on symptoms and groups of symptoms.</p>","PeriodicalId":8155,"journal":{"name":"Archives of environmental health","volume":"59 12","pages":"669-76"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00039890409602952","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26100080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between exposure to cadmium and blood pressure in Japanese peoples.","authors":"Isao Kurihara, Etsuko Kobayashi, Yasushi Suwazono, Mirei Uetani, Takeya Inaba, Mitsuhiro Oishiz, Teruhiko Kido, Hideaki Nakagawa, Koji Nogawa","doi":"10.1080/00039890409602957","DOIUrl":"https://doi.org/10.1080/00039890409602957","url":null,"abstract":"<p><p>The authors studied the effects of environmental cadmium exposure on blood pressure (BP). Subjects 1140 men and 1713 women, aged > or =50 yr lived in three areas of Japan considered \"unpolluted\" by cadmium. Multiple logistic regression analysis was used to evaluate relationships between hypertension/nonhypertension and cadmium concentrations in blood (B-Cd) or urine (U-Cd). Age, body mass index, drinking and smoking habits, and blood and urine chemistry data were incorporated into the model. Odds ratios for hypertension were significantly less than 1 in either gender when U-Cd was the indicator of cadmium exposure and hypertension was defined as systolic BP > or =140 mmHg and/or diastolic BP > or =90 mmHg. The results suggest a significant negative association between cadmium exposure and BP in inhabitants in Japan.</p>","PeriodicalId":8155,"journal":{"name":"Archives of environmental health","volume":"59 12","pages":"711-6"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00039890409602957","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26101728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Avima M Ruder, Martha A Waters, Mary Ann Butler, Tania Carreón, Geoffrey M Calvert, Karen E Davis-King, Paul A Schulte, Wayne T Sanderson, Elizabeth M Ward, L Barbara Connally, Ellen F Heineman, Jack S Mandel, Roscoe F Morton, Douglas J Reding, Kenneth D Rosenman, Glenn Talaska
{"title":"Gliomas and farm pesticide exposure in men: the upper midwest health study.","authors":"Avima M Ruder, Martha A Waters, Mary Ann Butler, Tania Carreón, Geoffrey M Calvert, Karen E Davis-King, Paul A Schulte, Wayne T Sanderson, Elizabeth M Ward, L Barbara Connally, Ellen F Heineman, Jack S Mandel, Roscoe F Morton, Douglas J Reding, Kenneth D Rosenman, Glenn Talaska","doi":"10.1080/00039890409602949","DOIUrl":"https://doi.org/10.1080/00039890409602949","url":null,"abstract":"<p><p>The National Institute for Occupational Safety and Health evaluated farm pesticide exposure and glioma risk in a study that included 457 glioma cases and 648 population-based controls, all adult men (18-80 yr old) and nonmetropolitan residents of Iowa, Michigan, Minnesota, and Wisconsin. Multiple logistic regressions were used to control for farm residence, age, age group, education, and exposure to other pesticides. No associations were found between glioma and 12 specific pesticides. We estimated adjusted odds ratios (ORs) and 95% confidence intervals (CIs) and found reduced glioma risk for insecticides (OR = 0.53, CI = 0.37-0.77), fumigants (OR = 0.57, CI = 0.34-0.95), and organochlorines (OR = 0.66, CI = 0.47-0.94). In analyses excluding proxy respondents (47% of cases) most CIs included 1.0. No positive association of farm pesticide exposure and glioma was found. Other farm exposures may explain the excess brain cancer risk seen in previous studies.</p>","PeriodicalId":8155,"journal":{"name":"Archives of environmental health","volume":"59 12","pages":"650-7"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00039890409602949","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26099573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Health hazards from volcanic gases: a systematic literature review.","authors":"Anna Hansell, Clive Oppenheimer","doi":"10.1080/00039890409602947","DOIUrl":"https://doi.org/10.1080/00039890409602947","url":null,"abstract":"<p><p>Millions of people are potentially exposed to volcanic gases worldwide, and exposures may differ from those in anthropogenic air pollution. A systematic literature review found few primary studies relating to health hazards of volcanic gases. SO2 and acid aerosols from eruptions and degassing events were associated with respiratory morbidity and mortality but not childhood asthma prevalence or lung function decrements. Accumulations of H2S and CO2 from volcanic and geothermal sources have caused fatalities from asphyxiation. Chronic exposure to H2S in geothermal areas was associated with increases in nervous system and respiratory diseases. Some impacts were on a large scale, affecting several countries (e.g., Laki fissure eruption in Iceland in 1783-4). No studies on health effects of volcanic releases of halogen gases or metal vapors were located. More high quality collaborative studies involving volcanologists and epidemiologists are recommended.</p>","PeriodicalId":8155,"journal":{"name":"Archives of environmental health","volume":"59 12","pages":"628-39"},"PeriodicalIF":0.0,"publicationDate":"2004-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00039890409602947","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26099571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Graciela Stutz, Javier Zamudio, Maria Emilia Santillán, Laura Vincenti, Marta Fiol de Cuneo, Rubin Daniel Ruiz
{"title":"The effect of alcohol, tobacco, and aspirin consumption on seminal quality among healthy young men.","authors":"Graciela Stutz, Javier Zamudio, Maria Emilia Santillán, Laura Vincenti, Marta Fiol de Cuneo, Rubin Daniel Ruiz","doi":"10.1080/00039890409603432","DOIUrl":"https://doi.org/10.1080/00039890409603432","url":null,"abstract":"<p><p>In this study, the authors examined the effects of alcohol, tobacco, and drug use on plasma testosterone and seminal parameters (in accordance with the World Health Organization's standards) in healthy Argentine medical students (n = 34). Some alterations in seminal parameters were detected in 19 (56%) subjects. Alcohol and tobacco use were correlated significantly, p = 0.005; subjects who used these substances exhibited a nonsignificant reduction in sperm concentration, motility, viability, and normal morphology. There was a significant decrease in sperm motility among students who used moderate amounts of aspirin (i.e., > or = 500 mg/wk). The authors concluded that alcohol, tobacco, and aspirin use could have had detrimental effects on seminal parameters and that men who wish to procreate should be warned of such effects. Doses, exposure time, and interactions with other variables deserve additional study.</p>","PeriodicalId":8155,"journal":{"name":"Archives of environmental health","volume":"59 11","pages":"548-52"},"PeriodicalIF":0.0,"publicationDate":"2004-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00039890409603432","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25959932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruth Koepke, Marcella Warner, Myrto Petreas, Angeles Cabria, Rogelio Danis, Mauricio Hernandez-Avila, Brenda Eskenazi
{"title":"Serum DDT and DDE levels in pregnant women of Chiapas, Mexico.","authors":"Ruth Koepke, Marcella Warner, Myrto Petreas, Angeles Cabria, Rogelio Danis, Mauricio Hernandez-Avila, Brenda Eskenazi","doi":"10.1080/00039890409603434","DOIUrl":"https://doi.org/10.1080/00039890409603434","url":null,"abstract":"<p><p>The authors measured the main ingredients of technical DDT (1,1,1-trichloro-2,2-bis(p-chlorophenyl [p,p'-DDT]) and its principal metabolite, 1,1-dichloro-2,2-bis (p-chlorophenyl)ethylene [p,p'-DDE]) in serum collected from 52 pregnant women in Tapachula, Chiapas, Mexico in 1998. The median lipid-adjusted serum levels for the women were 676 ng/g p,p'-DDT (range: 56-23,169 ng/g) and 4,843 ng/g p,p'-DDE (range: 113-41,964 ng/g). In regression analysis, serum DDT and DDE increased with age (test for trend, p = .022) but decreased with total lactation (test for trend, p < .001). Residence in a house that had ever been sprayed for malaria control was also related to serum DDT and DDE. This study provides evidence of high-level exposure to DDT and DDE among pregnant women living in Chiapas, Mexico, despite countrywide restrictions on its use at the time.</p>","PeriodicalId":8155,"journal":{"name":"Archives of environmental health","volume":"59 11","pages":"559-65"},"PeriodicalIF":0.0,"publicationDate":"2004-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00039890409603434","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25960424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Najwa Ouhoummane, Patrick Levallois, Suzanne Gingras
{"title":"Thyroid function of newborns and exposure to chlorine dioxide by-products.","authors":"Najwa Ouhoummane, Patrick Levallois, Suzanne Gingras","doi":"10.1080/00039890409603437","DOIUrl":"https://doi.org/10.1080/00039890409603437","url":null,"abstract":"<p><p>In this study, the authors compared thyroid function of newborns from 11 municipalities where drinking water was disinfected by chlorine dioxide (ClO2) with that of newborns from 15 municipalities using chlorine disinfection. They estimated the mean neonatal blood thyroid stimulating hormone (TSH) levels and proportion of congenital hypothyroidism cases using the results of the Quebec neonatal screening for congenital hypothyroidism for 32,978 newborns over the period 1993-1999. There was no significant increase in the TSH level and no excess of congenital hypothyroidism when all newborns exposed to ClO2 were considered. However, for newborns with low birth weight, mean TSH level was significantly higher among those exposed to ClO2 than for those in the reference group.</p>","PeriodicalId":8155,"journal":{"name":"Archives of environmental health","volume":"59 11","pages":"582-7"},"PeriodicalIF":0.0,"publicationDate":"2004-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00039890409603437","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25959299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ronit Peled, Dina Pilpel, Arkadi Bolotin, Leon Epstein, Haim Bibi, Michael Friger
{"title":"Young infants' morbidity and exposure to fine particles in a region with two power plants.","authors":"Ronit Peled, Dina Pilpel, Arkadi Bolotin, Leon Epstein, Haim Bibi, Michael Friger","doi":"10.1080/00039890409603441","DOIUrl":"https://doi.org/10.1080/00039890409603441","url":null,"abstract":"<p><p>This study investigated the effect of fine particulate matter (PM2.5) in ambient air on hospital admissions and emergency room (ER) visits among young children (0-3 yr) residing in 4 communities in southern Israel, within an area 5-25 km from the 2 power plants, which operate within 25 km of each other. Daily records of hospitalizations and ER visits for respiratory diseases at the 3 hospitals serving the region were examined for 9 mo, October 1, 2000-June 30, 2001. Mean PM2.5 concentrations for the four communities ranged from 11.6 to 28.1 microg/m3. Time series analysis revealed a statistically significant association (p < 0.05) between the numbers of hospitalizations and ER visits for respiratory symptoms and concentrations of PM2.5. This effect was evaluated for 0-3 lag days, directly, and for interactions with temperatures and seasonal parameters. The respiratory health of young children may be affected by 24 hr concentrations of PM2.5 < 60 microg/m3, the threshold proposed by both Israel and the United States.</p>","PeriodicalId":8155,"journal":{"name":"Archives of environmental health","volume":"59 11","pages":"611-6"},"PeriodicalIF":0.0,"publicationDate":"2004-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00039890409603441","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25959303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of byssinosis in a textile mill in northern Greece.","authors":"Lazaros Sichletidis, Antonios Antoniadis, Marianna Kakoura, Diamantis Chloros","doi":"10.1080/00039890409603442","DOIUrl":"https://doi.org/10.1080/00039890409603442","url":null,"abstract":"","PeriodicalId":8155,"journal":{"name":"Archives of environmental health","volume":"59 11","pages":"617"},"PeriodicalIF":0.0,"publicationDate":"2004-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/00039890409603442","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25959304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}