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GST gene family polymorphism and the risk of colorectal cancerin patients with type 2 diabetes GST基因家族多态性与结直肠癌合并2型糖尿病的发病风险
Contributions in medical studies Pub Date : 2021-01-01 DOI: 10.5114/ms.2021.109529
Justyna Klusek, A. Nasierowska-Guttmejer, K. Orlewska, Ł. Madej, J. Klusek, A. Cedro, S. Głuszek, Iwona Wawrzycka, E. Orlewska
{"title":"GST gene family polymorphism and the risk of colorectal cancer\u0000in patients with type 2 diabetes","authors":"Justyna Klusek, A. Nasierowska-Guttmejer, K. Orlewska, Ł. Madej, J. Klusek, A. Cedro, S. Głuszek, Iwona Wawrzycka, E. Orlewska","doi":"10.5114/ms.2021.109529","DOIUrl":"https://doi.org/10.5114/ms.2021.109529","url":null,"abstract":"","PeriodicalId":81014,"journal":{"name":"Contributions in medical studies","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85753142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The hospital ethical climate and its meaning in nursing work.A review of research results 医院伦理风气及其在护理工作中的意义。研究成果综述
Contributions in medical studies Pub Date : 2021-01-01 DOI: 10.5114/ms.2021.107462
Magdalena Dziurka, Patrycja Ozdoba, A. Jedynak, B. Dobrowolska
{"title":"The hospital ethical climate and its meaning in nursing work.\u0000A review of research results","authors":"Magdalena Dziurka, Patrycja Ozdoba, A. Jedynak, B. Dobrowolska","doi":"10.5114/ms.2021.107462","DOIUrl":"https://doi.org/10.5114/ms.2021.107462","url":null,"abstract":"","PeriodicalId":81014,"journal":{"name":"Contributions in medical studies","volume":"90 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80431659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current state and new aspects of fertility preservation surgery in some oncogynaecological diseases 一些妇科肿瘤保留生育能力手术的现状及新进展
Contributions in medical studies Pub Date : 2021-01-01 DOI: 10.5114/MS.2021.105005
Y. Kornovski, Y. Ivanova, S. Kostov, S. Slavchev, A. Yordanov
{"title":"Current state and new aspects of fertility preservation surgery \u0000in some oncogynaecological diseases","authors":"Y. Kornovski, Y. Ivanova, S. Kostov, S. Slavchev, A. Yordanov","doi":"10.5114/MS.2021.105005","DOIUrl":"https://doi.org/10.5114/MS.2021.105005","url":null,"abstract":"Preservation of reproductive function in young patients with uncompleted or unrealized reproductive plans in some malignant tumours of the female reproductive system has been a subject of study for many years, especially with the advances in assisted reproductive technologies. The main neoplasms that affect women in childbearing age are cervical cancer and ovarian tumours. In the current survey the novelties in the literature will be presented regarding the fertility preservation surgery in cervical cancer with size of tumour between 2 and 4 cm, granulosa cell ovarian tumours, and epithelial borderline ovarian tumours Streszczenie","PeriodicalId":81014,"journal":{"name":"Contributions in medical studies","volume":"77 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83896162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perceptions of the role of pharmacy assistants in providing patientcounselling in community pharmacies in Indonesia 对在印度尼西亚社区药房提供患者咨询的药房助理作用的认识
Contributions in medical studies Pub Date : 2021-01-01 DOI: 10.5114/ms.2021.107455
Gusti Ayu, Rai Widowati, Dyah Pradnyaparamita-Duarsa, Pande Putu-Januraga
{"title":"Perceptions of the role of pharmacy assistants in providing patient\u0000counselling in community pharmacies in Indonesia","authors":"Gusti Ayu, Rai Widowati, Dyah Pradnyaparamita-Duarsa, Pande Putu-Januraga","doi":"10.5114/ms.2021.107455","DOIUrl":"https://doi.org/10.5114/ms.2021.107455","url":null,"abstract":"Introduction: Patient counselling is a part of pharmaceutical services, where there is interaction between pharmacy workers with patients to provide drug information to improve patient safety. Pharmacy assistants are on the frontline of community pharmaceutical services in Indonesia, but regulations do not give them the authority to provide patient counselling. Aim of the research: This study explored pharmacy workers’ perceptions about the role of pharmacy assistants to provide patient counselling within the community. Material and methods: This was an exploratory qualitative study with 17 participants, comprising 9 pharmacists and 8 pharmacy assistants recruited through purposive sampling. Data were collected from May to June 2020. Semi-structured interviews were conducted to collect qualitative data on pharmacy workers’ perceptions regarding patient counselling provided by pharmacy assistants. Data analysis was performed thematically. Results: This is the first study to date to explore the perceptions of pharmacy workers regarding the role of patient counselling","PeriodicalId":81014,"journal":{"name":"Contributions in medical studies","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72847961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Comparison of vancomycin serum levels prior to and posttherapeutic drug monitoring in patients admitted to hospital 住院患者治疗前后药物监测万古霉素血清水平的比较
Contributions in medical studies Pub Date : 2021-01-01 DOI: 10.5114/ms.2021.109565
K. Eslami, Sasan Moogah, R. Ganji, F. Najmeddin, Sorour Moogahi
{"title":"Comparison of vancomycin serum levels prior to and post\u0000therapeutic drug monitoring in patients admitted to hospital","authors":"K. Eslami, Sasan Moogah, R. Ganji, F. Najmeddin, Sorour Moogahi","doi":"10.5114/ms.2021.109565","DOIUrl":"https://doi.org/10.5114/ms.2021.109565","url":null,"abstract":"","PeriodicalId":81014,"journal":{"name":"Contributions in medical studies","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84721540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the needs of patients suffering from rheumatoidarthritis – Scale of Needs of Patients Suffering from RheumaticDiseases (NPR) 类风湿关节炎患者需求评估-风湿病患者需求量表(NPR)
Contributions in medical studies Pub Date : 2021-01-01 DOI: 10.5114/ms.2021.112451
Kinga Żmijewska, Magdalena Staszkiewicz, Małgorzata Paplaczyk, A. Nowak, A. Gadek
{"title":"Assessment of the needs of patients suffering from rheumatoid\u0000arthritis – Scale of Needs of Patients Suffering from Rheumatic\u0000Diseases (NPR)","authors":"Kinga Żmijewska, Magdalena Staszkiewicz, Małgorzata Paplaczyk, A. Nowak, A. Gadek","doi":"10.5114/ms.2021.112451","DOIUrl":"https://doi.org/10.5114/ms.2021.112451","url":null,"abstract":"Introduction: Rheumatoid arthritis (rheumatoid arthritis) is manifested by pain, stiffness, deformation, and inflammation in the joints, mainly in the hand. There are 2 periods in the course of the disease: exacerbation and remission. Aim of the research: The objective of the study was to assess the needs of patients with rheumatoid arthritis (RA). Material and methods: The investigation included 124 patients treated in Krakow hospitals, who were divided into 2 groups: subjects","PeriodicalId":81014,"journal":{"name":"Contributions in medical studies","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89304312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic effect of Ziziphus lotus honey on hard palate ulcers in rats 酸枣蜜对大鼠硬腭溃疡的治疗作用
Contributions in medical studies Pub Date : 2021-01-01 DOI: 10.5114/MS.2021.105002
Leila Golpasandhagh, P. Salehi, B. Karimi, E. Moghimipour
{"title":"Therapeutic effect of Ziziphus lotus honey on hard palate ulcers \u0000in rats","authors":"Leila Golpasandhagh, P. Salehi, B. Karimi, E. Moghimipour","doi":"10.5114/MS.2021.105002","DOIUrl":"https://doi.org/10.5114/MS.2021.105002","url":null,"abstract":"Aim of the research: The aim of the study was to assess the effect of honey gel on the hard palate wound healing process in rats. Material and methods: In this interventional study, a total of 60 rats were randomly divided into 4 groups ( n = 15) including a control group, a honey gel group, a polyethylene glycol base group, and an oral honey group. Oral wounds were created (4 × 6 mm) on the anterior palatal rugae, and after 24 h the wounds were rinsed with normal saline solution and the stud- ied groups were treated by topical application of honey gel, polyethylene glycol base, and oral honey. On days 3, 7, and 14, five rats from each group were euthanized and histological samples were prepared, and the tissue slides were stained with haematoxylin eosin and observed under a light microscope. The mean number of neutrophils, fibroblasts, macrophage and blood vessel count, epithelialization, and the density of collagen fibres of each sample were assessed. Data were analysed using ANOVA and Kruskal-Wallis Test. Results: The number of blood vessels and the density of collagen fibres on day 14 were significantly higher in the honey gel group than in the control group ( p < 0.05). The number of blood vessels and the rate of epithelialization on day 14 were significantly increased in honey gel group compared to basal group ( p < 0.05). Other data were not statistically significant among the groups ( p > 0.05). Conclusions: Topical application of honey gel can accelerate the wound healing process of the hard palate.","PeriodicalId":81014,"journal":{"name":"Contributions in medical studies","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72919069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The importance of acute-phase proteins as markers in cancers 急性期蛋白作为癌症标志物的重要性
Contributions in medical studies Pub Date : 2021-01-01 DOI: 10.5114/ms.2021.112391
Paulina Zegarska, Urszula Markowska, Małgorzata Płoszaj
{"title":"The importance of acute-phase proteins as markers in cancers","authors":"Paulina Zegarska, Urszula Markowska, Małgorzata Płoszaj","doi":"10.5114/ms.2021.112391","DOIUrl":"https://doi.org/10.5114/ms.2021.112391","url":null,"abstract":"Acute-phase proteins (APPs) form a group of heterogeneous proteins whose synthesis takes place in the liver. This involves mediators such as cytokines and constitutes a response to acute inflammations, bacterial infections, tumours, and autoim- mune diseases. C-reactive protein is among the most important APPs. It participates in cancerous processes, especially in colon and rectal cancer. Another APP is haptoglobin. This glycoprotein prevents iron loss and kidney damage, and is associated with diagnostic neoplastic progression connected with fucosylation. Fucoso–haptoglobin is a highly effective marker for prognosis because an increased concentration of this complex is indicative of the distant metastases amount. Another APP is acidic α -glycoprotein (AGP), which increases to a serious level during acute inflammations and tumour-promoting processes. Its protective role involves platelet aggregation inhibition and chemotactic activity. The purpose of this study was to review the role of selected acute phase proteins in cancer promotion and progression.","PeriodicalId":81014,"journal":{"name":"Contributions in medical studies","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80996495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disturbances of the cognitive functions of vehicle drivers in selecteddiseases 特定疾病对车辆驾驶员认知功能的干扰
Contributions in medical studies Pub Date : 2021-01-01 DOI: 10.5114/ms.2021.107459
Rafał Łoś, Ewa Latała-Łoś
{"title":"Disturbances of the cognitive functions of vehicle drivers in selected\u0000diseases","authors":"Rafał Łoś, Ewa Latała-Łoś","doi":"10.5114/ms.2021.107459","DOIUrl":"https://doi.org/10.5114/ms.2021.107459","url":null,"abstract":"Cognitive dysfunctions such as memory, attention, and orientation may occur in many disease entities, including those not included in the sphere of mental disorders. Their presence can significantly affect the ability to drive vehicles and road safety. The literature on the subject is dominated by studies assessing the functioning on the road of people driving vehicles with diagnosed cognitive disorders of various aetiologies. It is natural to divide them into disorders resulting from the pa-thology of the central nervous system and cognitive dysfunctions present in the course of typically somatic diseases. Assess- ment of identified abnormalities usually involves several stages, but the most documented method of evaluating disorders is neuropsychological examination.","PeriodicalId":81014,"journal":{"name":"Contributions in medical studies","volume":"15 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83021689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Risk factors of falling among hospitalized patients with neurological disease – post-fall analysis 神经系统疾病住院患者跌倒的危险因素-跌倒后分析
Contributions in medical studies Pub Date : 2021-01-01 DOI: 10.5114/MS.2021.104996
Michaela Miertová, Ivana Bóriková, Martina Tomagová, Jaroslav Madleňák, M. Grendár, A. Barnau
{"title":"Risk factors of falling among hospitalized patients with neurological disease – post-fall analysis","authors":"Michaela Miertová, Ivana Bóriková, Martina Tomagová, Jaroslav Madleňák, M. Grendár, A. Barnau","doi":"10.5114/MS.2021.104996","DOIUrl":"https://doi.org/10.5114/MS.2021.104996","url":null,"abstract":"Introduction: Post-fall analysis of fall risk factors is an effective intervention in minimizing the fall risk in inpatients. Aim of the research: To identify significant fall risk factors in patients with neurological disease, who fell during hospitalization. Material and methods: Forty adult inpatients were included in a retrospective quantitative cross-sectional study, who fell in the neurological department in the period 01/2014–01/2020. The research protocol contains selected fall risk factors, the Morse Fall Scale (MFS), and the Barthel ADL Index. The Random Forest method was used to identify significant fall risk fac- tors. ROC with AUC was used to assess the predictive value of fall risk factors. Results: The mean age of the sample was 70.50 ±15.20 years. The most common fall risk factors in the sample included the following: gait, balance and mobility disorders, polymorbidity ≥ 5 medical diagnoses, and polypharmacotherapy ≥ 5 drug classes. The mean MFS score was high (75.8 ±26.6), and the after-fall MFS score increased (97.8 fall predictive of fall risk","PeriodicalId":81014,"journal":{"name":"Contributions in medical studies","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85408688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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