Cardiac electrophysiology review最新文献

{"title":"Cost evaluation of rhythm control methods for atrial fibrillation: evidence from CTAF.","authors":"Stanley Nattel,&nbsp;Gerald Lumer,&nbsp;Mario Talajic,&nbsp;Denis Roy","doi":"10.1023/B:CEPR.0000012384.57261.71","DOIUrl":"https://doi.org/10.1023/B:CEPR.0000012384.57261.71","url":null,"abstract":"<p><p>Atrial fibrillation (AF) is a highly prevalent arrhythmia that is difficult to treat and generates important health care costs. One consideration in the selection of various therapeutic options is the cost of a given treatment compared to that of alternatives. The Canadian Trial of Atrial Fibrillation (CTAF) evaluated the effectiveness of sinus rhythm maintenance with amiodarone compared to propafenone or sotalol in a prospective, randomized fashion. A subsequent CTAF substudy of the medical costs associated with amiodarone vs. propafenone/sotalol found that amiodarone decreased AF-related costs. This paper reviews the results of the CTAF cost-analysis substudy in the context of other analyses in the literature of the cost effectiveness of amiodarone in AF. The costs associated with amiodarone therapy are no greater than for other sinus rhythm maintenance drugs, and for some cost categories and some patient subgroups are likely to be less, despite amiodarone's greater therapeutic efficacy. However, additional considerations are important in evaluating the clinical place of amiodarone, including its adverse effect and pharmacokinetic profile. As well, the results of recent randomized clinical trials have highlighted the limitations of sinus rhythm maintenance as a primary therapeutic objective in AF. The decision about whether and at what point to use amiodarone in a given patient requires a careful analysis of the individual case, in terms of symptomatology during AF, the response to previous treatment regimes, and risk factors for various forms of adverse drug reactions.</p>","PeriodicalId":80888,"journal":{"name":"Cardiac electrophysiology review","volume":"7 3","pages":"211-4"},"PeriodicalIF":0.0,"publicationDate":"2003-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/B:CEPR.0000012384.57261.71","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24177466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rationale for the Atrial Fibrillation and Congestive Heart Failure (AF-CHF) trial.","authors":"D. Roy","doi":"10.1016/S1071-9164(03)00536-0","DOIUrl":"https://doi.org/10.1016/S1071-9164(03)00536-0","url":null,"abstract":"","PeriodicalId":80888,"journal":{"name":"Cardiac electrophysiology review","volume":"29 1","pages":"208-10"},"PeriodicalIF":0.0,"publicationDate":"2003-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1071-9164(03)00536-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"56490189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of life variables in the selection of rate versus rhythm control in patients with atrial fibrillation: observations from the Canadian Trial of Atrial Fibrillation.","authors":"Paul Dorian,&nbsp;Iqwal Mangat","doi":"10.1023/B:CEPR.0000012395.33292.cd","DOIUrl":"https://doi.org/10.1023/B:CEPR.0000012395.33292.cd","url":null,"abstract":"<p><p>Many patients with atrial fibrillation develop symptoms attributable to the cardiac arrhythmia itself. These symptoms may be improved either by restoring sinus rhythm or by controlling the rapid and irregular ventricular response that often accompanies this arrhythmia. One of the principal goals of therapy of atrial fibrillation management is improvement of patient symptoms; it is important to quantify these symptoms by some form of quality of life analysis. The Canadian Trial of Atrial Fibrillation (CTAF) was a multi-centre randomized clinical trial of amiodarone compared with either propafenone or sotalol in patients with recent atrial fibrillation. The quality of life (QOL) substudy of CTAF was a prospective, comprehensive assessment of quality of life of patients enrolled in CTAF. Summary measures of physical and mental health on the generic QOL scale (SF-36) improved significantly with treatment from baseline to 3 months (41.9 +/- 9.6 to 43.7 +/- 9.2, p = 0.001 for the physical component and 47.5 +/- 10.4 to 49.0 +/- 9.8, p = 0.023 for the mental component). On an arrhythmia specific scale (SCL), a significant and larger improvement was noted from baseline to 3 months in both arrhythmia symptom frequency and severity (symptom frequency from 20.4 +/- 9.4 to 16.2 +/- 9.5, symptom severity from 16.7 +/- 8.2 to 12.9 +/- 7.6, both p < 0.001). The quality of life improvements were similar in the amiodarone group compared to the sotalol or propafenone groups, both for the SF-36 and the disease-specific symptom checklist (SCL) measures. In contrast, an atrial fibrillation severity scale (AFSS) did show differences between the assigned drug therapies, which were associated with different rates of arrhythmia recurrence in the parent study. By 3 months global well-being was significantly worse for patients who had recurrent atrial fibrillation compared to those who did not (6.9 +/- 1.8 versus 7.4 +/- 1.8, p = 0.04). Similarly, symptom severity at 3 months was 11.8 +/- 7.4 for patients without recurrence, compared to 14.8 +/- 7.4 for those with recurrence ( p = 0.001). Interestingly, none of the usual clinical variables that might be perceived to be associated with quality of life, e.g., male versus female sex, age, NYHA class, beta blocker use, and ejection fraction, had much impact on subjective quality of life measures. Quality of life improves with treatment atrial fibrillation and at least some of these improvements are related to the restoration and maintenance of sinus rhythm.</p>","PeriodicalId":80888,"journal":{"name":"Cardiac electrophysiology review","volume":"7 3","pages":"276-9"},"PeriodicalIF":0.0,"publicationDate":"2003-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/B:CEPR.0000012395.33292.cd","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24177920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amiodarone for the restoration of sinus rhythm in patients with atrial fibrillation.","authors":"Panos E Vardas,&nbsp;George E Kochiadakis","doi":"10.1023/B:CEPR.0000012400.34597.00","DOIUrl":"https://doi.org/10.1023/B:CEPR.0000012400.34597.00","url":null,"abstract":"<p><p>Although the use of amiodarone for the treatment of atrial fibrillation has increased, reports of its use for the restoration of sinus rhythm have been conflicting. In a recent prospective, randomized, single-blind, placebo controlled study, we examined the efficacy and safety of amiodarone as initial treatment to restore sinus rhythm in patients with atrial fibrillation of varying duration. We studied 335 patients (169 men, 166 women), aged 27-78 years (mean age 65 +/- 10 years), with symptomatic atrial fibrillation, who presented to the emergency room or to our clinic. Patients randomized to amiodarone ( n = 173) received 300 mg intravenously over 1 hour followed by 20 mg/kg over 24 hours. Oral administration was initiated simultaneously at 600 mg/day in 3 divided doses for one week followed by 400 mg/day, in two doses, for three weeks. Amiodarone was almost twice as likely as placebo to restore sinus rhythm (85% vs. 43%, p < 0.0001). Larger left atrial size and longer duration of atrial fibrillation decreased amiodarone's effectiveness. These factors were also associated with longer duration of treatment before conversion to sinus rhythm. We observed relatively few and only minor complications despite relatively high doses of amiodarone administered to achieve high serum concentrations. In conclusion, our findings indicate that amiodarone is an effective and safe antiarrhythmic drug even when administered in large doses. It may be used for the restoration of sinus rhythm when rapid cardioversion is not needed.</p>","PeriodicalId":80888,"journal":{"name":"Cardiac electrophysiology review","volume":"7 3","pages":"297-9"},"PeriodicalIF":0.0,"publicationDate":"2003-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/B:CEPR.0000012400.34597.00","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24177354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pacing to prevent atrial fibrillation after coronary artery bypass grafting. What works, what doesn't: insights from Bachmann's Bundle pacing.","authors":"Andreas Goette","doi":"10.1023/a:1027415600883","DOIUrl":"https://doi.org/10.1023/a:1027415600883","url":null,"abstract":"<p><p>Atrial fibrillation (AF) occurs in about 30% of patients after open heart surgery and is associated with longer hospital stay and greater cost. Therefore, prophylactic measures are warranted to reduce the incidence of AF in postoperative patients. In addition to pharmacologic approaches, various atrial pacing strategies (right atrial, biatrial, and Bachmann's Bundle pacing) have been evaluated. Although, meta-analyses including several studies seem to demonstrate an overall benefit of atrial pacing, many findings are conflicting. The impact of Bachmann's bundle (BB) pacing on postoperative AF was studied in a recent randomized, prospective trial that included 161 patients. The incidence of postoperative AF was not reduced by BB pacing or right atrial pacing compared to non-paced controls (37% vs. 48% vs. 42%; P = ns). An important finding of this study was, however, that the paced P-wave duration, a risk factor for postoperative AF, was increased during right atrial pacing compared to BB pacing. In addition, pacing thresholds were significantly better at BB compared to right atrial locations. Thus, in contrast to biatrial pacing strategies, pacing at BB does not reduce the overall incidence of postoperative AF. However, BB offers favorable pacing capabilities and is less arrhythmogenic compared to right atrial pacing during the postoperative period.</p>","PeriodicalId":80888,"journal":{"name":"Cardiac electrophysiology review","volume":"7 2","pages":"154-7"},"PeriodicalIF":0.0,"publicationDate":"2003-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1027415600883","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24076264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amiodarone prevents symptomatic atrial fibrillation and reduces the risk of cerebrovascular accidents and ventricular tachycardia after open heart surgery: results of the Atrial Fibrillation Suppression Trial (AFIST).","authors":"Jeffrey Kluger,&nbsp;C Michael White","doi":"10.1023/a:1027471718630","DOIUrl":"https://doi.org/10.1023/a:1027471718630","url":null,"abstract":"<p><strong>Background: </strong>Atrial fibrillation (AF) is a common complication after cardiothoracic surgery (CTS). The role of amiodarone added to beta blocker as a preventive strategy in elderly patients undergoing CTS is not known. The Atrial Fibrillation Suppression Trial (AFIST) was a double blind, placebo-controlled trial that evaluated the efficacy of oral amiodarone in patients 60 years or older undergoing CTS. Beta blockers were administered as part of a critical pathway.</p><p><strong>Methods: </strong>Elderly patients (n = 220, mean age 72 +/- 6.7 years) received amiodarone (n = 120) or placebo (n = 100). Patients enrolled less than 5 days before CTS received 6 g of drug over 6 days beginning on the day prior to OHS. Patients enrolled 5 days before CTS received 7 g of study drug over 9-10 days, starting on preoperative day 4 or 5.</p><p><strong>Results: </strong>Amiodarone treated patients had a lower incidence of AF (22.5% vs. 38%, p = 0.01), symptomatic AF (4.2% vs. 18%, p = 0.001), cerebral vascular accident (1.7 vs. 7.0%, p = 0.04), and ventricular tachycardia (1.7% vs. 7.0%, p = 0.04) vs. placebo. Beta blocker use (87.5% vs. 91.0% ), nausea (26.7% vs. 16%, p = 0.056), symptomatic bradycardia (7.5% vs. 7%, p = 0.89), hypotension (14.2% vs. 10.0%) and 30 day mortality (3.3 vs. 4.0%, p = 0.79) were similar. Amiodarone treated patients receiving the 4/5 day preoperative regimen had a reduced incidence of AF (19.6% vs. 38%, p = 0.013), while those receiving the 1-day preoperative regimen showed a trend (25% vs. 38%, p = 0.06) vs. placebo.</p><p><strong>Conclusions: </strong>In an elderly population undergoing CTS, Amiodarone prophylaxis reduces AF, the incidence of symptomatic AF, cerebrovascular accident and ventricular tachycardia.</p>","PeriodicalId":80888,"journal":{"name":"Cardiac electrophysiology review","volume":"7 2","pages":"165-7"},"PeriodicalIF":0.0,"publicationDate":"2003-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1027471718630","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24076123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacological approach for the prevention of atrial fibrillation after cardiovascular surgery.","authors":"Allen J Solomon","doi":"10.1023/a:1027475819539","DOIUrl":"https://doi.org/10.1023/a:1027475819539","url":null,"abstract":"<p><p>Atrial fibrillation (AF) is a common complication of cardiovascular surgery. The two most important risk factors for its development are advancing age and a preoperative history of AF. Long-term sequelae, such as a stroke, are uncommon, however, atrial fibrillation frequently results in increased length and cost of hospitalization. Strategies to prevent postoperative AF include perioperative beta-blockers, amiodarone, and atrial pacing. These strategies are most effective in high-risk patients. When AF does occur, treatment includes control of the ventricular rate, systemic anticoagulation, and conversion to sinus rhythm.</p>","PeriodicalId":80888,"journal":{"name":"Cardiac electrophysiology review","volume":"7 2","pages":"172-7"},"PeriodicalIF":0.0,"publicationDate":"2003-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1027475819539","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24076125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanisms of biatrial pacing for prevention of postoperative atrial fibrillation--insights from a clinical trial.","authors":"Katherine Fan,&nbsp;Kathy Lee,&nbsp;Chu-Pak Lau","doi":"10.1023/a:1027463516813","DOIUrl":"https://doi.org/10.1023/a:1027463516813","url":null,"abstract":"<p><p>Atrial fibrillation (AF) occurs in a high proportion of patients after cardiac surgery and is associated with increased morbidity and longer hospital stay. Beta-blockers and amiodarone have been shown to reduce the incidence, but AF still occurs in up to 25% despite pre-treatment. The mechanisms of AF after cardiac surgery are presumably multifactorial. The transient nature of postoperative AF suggests a reversible trigger in patients with susceptible underlying electrophysiological substrates such as abnormal automaticity and conduction delay due to atrial incisions, ischemia and preexisting disease). These could result in atrial premature beats (APBs) and prolonged atrial activation causing lengthening of the P wave. Prophylactic atrial pacing (single- or multi-site) is reported to be effective in patients at high risk for postoperative AF. The mechanisms are probably a combination of preventing bradycardia-induced arrhythmias, overdrive suppression of APBs, eliminating compensatory pauses after APBs and reduction of dispersion of refractoriness. By reducing non-uniform and asynchronous activation resulting from anatomic or functional block, multi-site pacing could improve local excitability and reduce the window of opportunity for AF initiation. We found that the incidence of AF after coronary bypass surgery (CABG) was significantly reduced in patients who received prophylactic biatrial overdrive pacing (BiA) compared with single site left atrial (LA) or right atrial (RA) pacing or no pacing. (BiA 12.5% versus LA 36.4%; RA 33.3% or control 41.9%; P < 0.05). BiA pacing was associated with the greatest reduction of P wave dispersion compared with single site pacing or control (BiA 42 +/- 8%; LA 13 +/- 6%; RA 10 +/- 9%; P < 0.05). Prophylactic postoperative BiA pacing is thus a reasonable and attractive strategy for reducing the risk for postoperative AF.</p>","PeriodicalId":80888,"journal":{"name":"Cardiac electrophysiology review","volume":"7 2","pages":"147-53"},"PeriodicalIF":0.0,"publicationDate":"2003-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1027463516813","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24076263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rate-control versus conversion strategy in postoperative atrial fibrillation: trial design and pilot study results.","authors":"John K Lee,&nbsp;George J Klein,&nbsp;Andrew D Krahn,&nbsp;Raymond Yee,&nbsp;Kelly Zarnke,&nbsp;Christopher Simpson,&nbsp;Allan Skanes","doi":"10.1023/a:1027428003609","DOIUrl":"https://doi.org/10.1023/a:1027428003609","url":null,"abstract":"<p><p>Atrial fibrillation (AF) remains a frequent complication of cardiac surgery. The optimal treatment strategy has not been established. Retrospective studies have suggested that a primary rate-control strategy may be equivalent to a strategy that restores sinus rhythm. Fifty patients with postoperative atrial fibrillation were randomly assigned to a strategy of antiarrhythmic therapy +/- electrical cardioversion or ventricular rate control. Anticoagulation with heparin overlapped with coumadin was administered to both arms. The primary endpoint of the study was time to conversion to sinus rhythm analyzed by the Kaplan-Meier method. The effects of strategy on hospital length of stay was examined as well as the incidence of recurrent AF. This study demonstrated no significant difference between an antiarrhythmic conversion strategy (n = 27) and a rate-control strategy (n = 23) in time to conversion to sinus rhythm (11.2 +/- 3.2 vs. 11.8 +/- 3.9 hours; p = 0.8). With Cox multivariate analysis to control for the effects of age, sex, beta-blocker usage, and type of surgery, the conversion strategy showed a trend toward reducing the time from treatment to restoration of sinus rhythm (p = 0.08). The length of hospital stay was reduced in the antiarrhythmic arm compared with the rate-control strategy (9.0 +/- 0.7 vs. 13.2 +/- 2.0 days; p = 0.05). In hospital relapse rates in the antiarrhythmic arm were 30% compared with 57% in the rate-control strategy (p = 0.24). At the termination of the study, 91% of the patients in the rate-control arm were in sinus rhythm compared with 96% in the antiarrhythmic arm. In conclusion, this pilot study shows little difference between a rate-control strategy and a strategy to restore/maintain sinus rhythm. Regardless of the strategy, majority of patients will be in sinus rhythm after two months. A larger randomized, controlled study is needed to assess the impact of restoration of sinus rhythm on length of stay.</p>","PeriodicalId":80888,"journal":{"name":"Cardiac electrophysiology review","volume":"7 2","pages":"178-84"},"PeriodicalIF":0.0,"publicationDate":"2003-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1027428003609","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24076126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aortic fat pad destruction and post operative atrial fibrillation.","authors":"Zev Davis,&nbsp;H Kurt Jacobs","doi":"10.1023/a:1027480020448","DOIUrl":"https://doi.org/10.1023/a:1027480020448","url":null,"abstract":"<p><strong>Introduction: </strong>Atrial arrhythmias are a common complication of cardiac surgery. Reports describing pericardiac neurogenic tissue led us to hypothesize that removal of the aortic fat pad could cause an autonomic imbalance and contribute to atrial arrhythmias following cardiac surgery.</p><p><strong>Methods: </strong>A randomized prospective pilot study (n =131) was conducted to test our hypotheses. Patients underwent conventional cardio-pulmonary bypass surgery (CPB) or off pump coronary bypass surgery (OPCAB). The fat pad was either left intact or removed. The incidence of de novo atrial arrhythmias during the patient's hospital stay was tabulated. Patients with peri-operative myocardial infarction or pre-existing atrial or supraventricular arrhythmias were excluded. The randomization schedule was made subservient to clinical judgment at surgery. After promising preliminary results, an extension study (n =189 patients, total patients =320) was performed which employed the same definitions and interventions but was a sample of convenience. The data of this second study have not been previously published.</p><p><strong>Results: </strong>In the pilot study, in demographically similar groups, logistic regression demonstrated a significantly elevated atrial arrhythmia incidence when the fat pad was removed (Odds ratio 3.49, 95% confidence intervals 1.09 to 11.18). A chi-square analysis of these same data, however, (4 fibrillations in 58 patients with fat pad intact versus 15 fibrillation in 73 patients with fat pad removed; P = 0.051) suggested that the importance of the fat pad status was not definite. Overall, atrial arrhythmias were present in 19 of 131 patients (14.5%). In the extension study, in contrast to the pilot data, the data did not demonstrate any contribution of fat pad status to the incidence of atrial fibrillation.</p><p><strong>Conclusions: </strong>Although we feel that our hypothesis remains viable, retention of the aortic fat pad during coronary artery bypass surgery may not be related to a decreased incidence of post operative atrial arrhythmias.</p>","PeriodicalId":80888,"journal":{"name":"Cardiac electrophysiology review","volume":"7 2","pages":"185-8"},"PeriodicalIF":0.0,"publicationDate":"2003-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1023/a:1027480020448","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24076127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}