Annals of Plastic SurgeryPub Date : 2025-09-01Epub Date: 2025-06-13DOI: 10.1097/SAP.0000000000004429
Alison S Bae, Andreas Markus Loening, Kassandra Carrion, Victoria Posternak, Hui He, Stanley P Leong, Dung H Nguyen
{"title":"Lymphatic Regeneration Visualized on Magnetic Resonance Imaging After Placement of Aligned Nanofibrillar Collagen Scaffolds for Treatment of Lymphedema.","authors":"Alison S Bae, Andreas Markus Loening, Kassandra Carrion, Victoria Posternak, Hui He, Stanley P Leong, Dung H Nguyen","doi":"10.1097/SAP.0000000000004429","DOIUrl":"10.1097/SAP.0000000000004429","url":null,"abstract":"<p><strong>Background and objectives: </strong>Lymphatic regeneration has been shown after placement of aligned nanofibrillar collagen scaffolds (BioBridge) in animal models and humans with multiple imaging modalities including indocyanine green lymphography, histology, and computed tomography. The aim of our study is to demonstrate new lymphatic regeneration visualized on magnetic resonance imaging (MRI) after aligned nanofibrillar collagen scaffold placement.</p><p><strong>Methods: </strong>We retrospectively studied patients with extremity lymphedema who underwent placement of BioBridge. Additionally, most of these patients had lymphaticovenous bypass, vascularized lymph node transfer, or liposuction. MR lymphangiogram was performed at least a year postoperatively.</p><p><strong>Results: </strong>The postoperative MRI images demonstrate new lymphatic collectors in both upper and lower extremities where aligned nanofibrillar collagen scaffolds were implanted from sites of lymphaticovenous bypass or vascularized lymph node transfer in the distal limb to proximal lymph node basins in the groin or axilla. Additionally, new lymphatic collectors are visualized between left and right lymph node basins in the groin or supraclavicular region when aligned nanofibrillar collagen scaffolds were placed from the effected extremity to the contralateral lymph node basin.</p><p><strong>Conclusions: </strong>For these patients, lymphatic regeneration along with decrease in limb volume suggests that Aligned nanofibrillar collagen scaffold placement generates functional lymphatic collectors that improve lymphedema.</p>","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":" ","pages":"286-291"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ramana Kolady, Paul G Guirguis, Mark P Youssef, Andrew F Ibrahim, Ankit Punreddy, Jake A Fiore, Michaela Malin, Mark Ayob, Paul Soliman, Mina Botros
{"title":"Evaluating Editor-in-Chief Diversity in High-Impact Plastic Surgery Journals: A 20-Journal Analysis.","authors":"Ramana Kolady, Paul G Guirguis, Mark P Youssef, Andrew F Ibrahim, Ankit Punreddy, Jake A Fiore, Michaela Malin, Mark Ayob, Paul Soliman, Mina Botros","doi":"10.1097/SAP.0000000000004495","DOIUrl":"https://doi.org/10.1097/SAP.0000000000004495","url":null,"abstract":"<p><strong>Background: </strong>Lack of diversity in medical research is a growing concern. Editorial boards play a significant role in shaping scientific discourse; thus, it is imperative that they convey a variety of perspectives. This study examines editorial boards of the top 20 plastic surgery journals, focusing on the demographic and academic backgrounds of editors-in-chief.</p><p><strong>Methods: </strong>Editorial boards of the top 20 plastic surgery journals by impact factor were reviewed for editor-in-chief information through journal websites and public sources. Information on demographic characteristics, academic background, years since training completion, and leadership were collected by 2 independent reviewers. H-indices were obtained from the Scopus database.</p><p><strong>Results: </strong>Among 15 editors-in-chief, 93.3% were male (n = 14), and 6.7% were female (n = 1); 66.7% of editors-in-chief were White (n = 10), and 33.3% were Asian (n = 5). Mean years since training completion was 26.6 ± 10.3 years. Furthermore, 66.7% of editors-in-chief held an MD (n = 10), 26.7% held an MD and PhD (n = 4), and 6.7% held a master's degree and PhD (n = 1). Editors-in-chief residency training backgrounds included 6.7% trained in general surgery (n = 1), 33.3% trained in plastic surgery (n = 5), 26.7% trained in both general and plastic surgery (n = 4), and 26.7% trained in other specialties (n = 4). All editors-in-chief held professorship positions, 53.3% held chair positions (n = 8), 60.0% served as current or past society presidents (n = 9), and 60.0% held director roles (n = 9).</p><p><strong>Conclusion: </strong>This study highlights limited gender and racial diversity among plastic surgery journal editors-in-chief. Efforts must continue to address this issue and promote diversity in leadership roles.</p>","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":"95 3","pages":"315-317"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical Treatment of Fingertip Defects Associated With Nail Bed Injuries: A Dual-Flap Reconstruction Protocol.","authors":"Shuang Wang, Huali Gu, Haiping Zhang, Xiaogang Zhou, Bingbing Wu","doi":"10.1097/SAP.0000000000004477","DOIUrl":"https://doi.org/10.1097/SAP.0000000000004477","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze the aesthetic and functional results of a dual-flap reconstruction protocol for nail expansion by recessing the nail fold to increase the exposed nail matrix after repair of finger pulp defect.</p><p><strong>Methods: </strong>A total of 18 patients who underwent a dual-flap reconstruction protocol were retrospectively reviewed. We increased nail bed exposure by recessing a Y-V flap of eponychium and reconstructed the pulp with volar V-Y advancement flaps or homodigital island flaps depending on the injury geometry. A controllable 0.3- to 0.45-cm-wide recession of eponychium was feasible. The eponychial Y-V recession flap was separated from the nail matrix and slid proximally to expose more nail matrix, thereby effectively lengthening the exposed nail bed.</p><p><strong>Results: </strong>The flaps survived in all patients. The exposed nail beds were lengthened 0.3 to 0.45 cm. The fingertips had smooth and natural nail plates with inconspicuous scars on both the eponychium and pulp and no deformities. The mobility of injured and uninjured contralateral fingers did not differ statistically. All patients and observers were satisfied with the appearance and function of the reconstructed fingertips.</p><p><strong>Conclusions: </strong>The eponychial Y-V recession flap combined with volar soft tissue reconstruction provided for the aesthetic and functional restoration of the fingertip defects with partial nail bed defect.</p>","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":"95 3","pages":"268-272"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harshavardhan Shetty, Joseph Thomas, Kanthilatha Pai, Anuradha C K Rao, Tanvi Rao, Priyanaka Patel, Swathi Prabhu
{"title":"Inverted Follicular Keratosis of the Lower Eyelid-A Diagnostic Conundrum.","authors":"Harshavardhan Shetty, Joseph Thomas, Kanthilatha Pai, Anuradha C K Rao, Tanvi Rao, Priyanaka Patel, Swathi Prabhu","doi":"10.1097/SAP.0000000000004471","DOIUrl":"https://doi.org/10.1097/SAP.0000000000004471","url":null,"abstract":"<p><strong>Background: </strong>Ulceroproliferative lesions involving the eyelids can be due to several causes, chief among them being squamous cell carcinoma (SCC). It is imperative to distinguish it from various mimics owing to the limited surgical therapy that can be offered at the site. Inverted follicular keratosis (IFK) is a rare benign epidermal tumor that arises from the infundibular portion of the hair follicle. The endophytic growth pattern and histological features closely mimic SCC especially in small or superficial biopsies, making accurate diagnosis challenging.</p><p><strong>Case presentation: </strong>A 76-year-old male patient who presented with a nodular ulcerative lesion on the right lower eyelid that gradually increased in size over a span of 20 years. The lesion was excised through pentagonal full-thickness resection with 2-mm margins. Primary closure was achieved with the aid of lateral canthotomy to reduce tension. The postoperative course was uneventful. Wound healing was complete with normal eyelid closure and no ectropion. Histopathological examination revealed features characteristic of IFK, including an endophytic proliferation of basaloid and squamous cells, numerous squamous eddies, keratin-filled cysts, and absence of cellular atypia or mitotic activity. p53 immunohistochemistry showed wild-type expression, supporting the benign nature of the lesion.</p><p><strong>Conclusions: </strong>IFK can clinically and histologically resemble SCC, particularly in limited biopsy samples. Surgical excision with appropriate margin clearance and functional eyelid reconstruction ensures both curative and functional outcomes. Awareness of this benign entity and recognition of its distinguishing histopathological features are crucial to avoid overtreatment and to ensure appropriate patient management. Complete excision remains the treatment of choice and has excellent prognosis.</p>","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":"95 3S Suppl 1","pages":"S75-S77"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jingwei Feng, Jiajun Zhi, Fangru Wang, Yuan Zhang, Bingqing Wang
{"title":"Using Preauricular Rotation Flaps to Repair Cartilage Exposure in the Triangular Fossa Area After Ear Reconstruction: Clinical Techniques and Evaluation.","authors":"Jingwei Feng, Jiajun Zhi, Fangru Wang, Yuan Zhang, Bingqing Wang","doi":"10.1097/SAP.0000000000004486","DOIUrl":"https://doi.org/10.1097/SAP.0000000000004486","url":null,"abstract":"<p><strong>Background: </strong>Cartilage exposure in the triangular fossa following ear reconstruction is a challenging complication due to the region's concave morphology and limited soft tissue coverage. This study evaluates the efficacy of preauricular rotation flaps for repairing such defects.</p><p><strong>Methods: </strong>Twenty-four patients with cartilage exposure in the triangular fossa after ear reconstruction underwent repair using preauricular rotation flaps at the Plastic Surgery Hospital of the Chinese Academy of Medical Sciences (2018-2023). The surgical technique emphasized flap design from the preauricular region, tension-free rotation, and integration with local skin. Outcomes were assessed by flap survival, triangular fossa morphology restoration, donor site scarring, and patient satisfaction. Follow-up averaged 18.5 months (range, 6-36 months).</p><p><strong>Results: </strong>Complete flap survival was achieved in 22 cases (91.7%), whereas 2 cases (8.3%) experienced partial superficial necrosis that healed with conservative treatment. Triangular fossa morphology restoration was rated excellent in 16 cases (66.7%), good in 6 (25.0%), and poor in 2 (8.3%). Donor site scarring was minimal in 20 cases (83.3%) and moderate in 4 (16.7%), with no significant scarring observed. The average patient satisfaction score was 4.3/5. No recurrent cartilage exposure or secondary repairs were required during follow-up.</p><p><strong>Conclusion: </strong>The preauricular rotation flap provides an effective solution for triangular fossa cartilage exposure after ear reconstruction, offering both functional and aesthetic benefits. This technique is straightforward to perform with a short learning curve and achieves high success rates with good patient satisfaction.</p>","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":"95 3","pages":"279-285"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144939302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of Plastic SurgeryPub Date : 2025-09-01Epub Date: 2025-06-27DOI: 10.1097/SAP.0000000000004426
Rachana Suresh, Anirudh Buddhiraju, Visakha Suresh, A Lee Dellon, Vishal Hegde, Sami H Tuffaha, Ala Elhelali
{"title":"Neuromas and Persistent Postoperative Pain Following Total Knee Arthroplasty.","authors":"Rachana Suresh, Anirudh Buddhiraju, Visakha Suresh, A Lee Dellon, Vishal Hegde, Sami H Tuffaha, Ala Elhelali","doi":"10.1097/SAP.0000000000004426","DOIUrl":"10.1097/SAP.0000000000004426","url":null,"abstract":"<p><strong>Purpose: </strong>Persistent postoperative knee pain after primary total knee arthroplasty (TKA) is often an indication for revision surgery and has a multifactorial etiology. Periarticular neuromas of nerves innervating the joint, ligaments, or overlying skin are important but misdiagnosed causes of persistent knee pain following knee surgery. This study aimed to characterize the incidence and sequelae of peripheral neuromas in TKA patients.</p><p><strong>Methods: </strong>We utilized the TriNetX research network to identify TKA patients experiencing persistent knee pain lasting more than 3 months between 2016-2024, excluding cases with acute postoperative pain and implant-related causes, and identified patients diagnosed with neuromas. We then compared the rate of revision between patients with persistent knee pain with confirmed neuroma diagnoses and those without, and evaluated the utilization of surgical and nonsurgical interventions.</p><p><strong>Results: </strong>Of 446,969 primary TKA patients, 111,533 (25.0%) experienced persistent pain, of whom 5785 (5.2%) were diagnosed with neuromas. Among those diagnosed, 19% received a diagnosis within 1 year of TKA, 25.8% between one and 3 years, and 55.2% after 3 years. Revision rates were similar in both groups (0.5% vs 0.5%). While 10.5% of neuroma patients received an intervention, only 3.6% underwent definitive surgical intervention.</p><p><strong>Conclusions: </strong>One-fourth of TKA patients have persistent knee pain not associated with joint or implant-related factors, yet only around 5% are definitively diagnosed with a neuroma, suggesting potential underdiagnosis. The high risk of nerve injury during standard TKA incisions should warrant a high index of suspicion for neuromas in patients with refractory persistent knee pain.</p>","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":" ","pages":"292-296"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144537855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brittany Davis, Jessica Hale, Elaine Lelli, Mark A Brzezienski
{"title":"Prepectoral Passot-Type Immediate Breast Reconstruction With the Use of Acellular Dermal Matrix in Grades 2 and 3 Ptosis.","authors":"Brittany Davis, Jessica Hale, Elaine Lelli, Mark A Brzezienski","doi":"10.1097/SAP.0000000000004447","DOIUrl":"https://doi.org/10.1097/SAP.0000000000004447","url":null,"abstract":"<p><strong>Introduction: </strong>Implant-based breast reconstruction after skin-sparing mastectomy remains one of the most frequently used methods of breast reconstruction in the US. Patients with large, ptotic breasts often face poorer outcomes. We hypothesized that implant-based breast reconstruction with auto-augmentation techniques can minimize problems with acellular dermal matrices (ADM) by using less, and providing the benefit of prepectoral placement.</p><p><strong>Methods: </strong>We performed a single institution retrospective review of all patients with grade 2 or 3 ptosis following subpectoral and prepectoral BR with autologous dermal tissue and/or ADM over a 5-year period. Outcomes, complications, and costs between the subpectoral, prepectoral, and tissue expander (TE) with ADM groups were compared within our sample.</p><p><strong>Results: </strong>Women in the Passot-type reconstruction groups had significantly higher body mass indices and rates of radiation therapy. When body mass index and radiation were controlled for, there were no significant differences in complication rates between prepectoral Passot, subpectoral Passot, and the TE/ADM group. Passot-type reconstructions can be significantly less expensive than TE/ADM.</p><p><strong>Conclusions: </strong>Prepectoral Passot-type reconstruction is a viable method to limit complications of subpectoral approaches at roughly half the cost of a TE/ADM approach.</p>","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":"95 3S Suppl 1","pages":"S29-S36"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noah Alter, Claiborne Lucas, Ricardo Torres-Guzman, Andrew James, Amy Stone, Maria E Powell, Scott Corlew, Weixin Liu, Bowen Qu, Zhijun Yin, Andrea Hiller, Michael Golinko, Matthew E Pontell
{"title":"From Support Vector Machines to Neural Networks: Advancing Automated Velopharyngeal Dysfunction Detection in Patients With Cleft Palate.","authors":"Noah Alter, Claiborne Lucas, Ricardo Torres-Guzman, Andrew James, Amy Stone, Maria E Powell, Scott Corlew, Weixin Liu, Bowen Qu, Zhijun Yin, Andrea Hiller, Michael Golinko, Matthew E Pontell","doi":"10.1097/SAP.0000000000004460","DOIUrl":"https://doi.org/10.1097/SAP.0000000000004460","url":null,"abstract":"<p><strong>Background: </strong>The generation of intelligible speech is the single most important outcome after cleft palate repair. The development of velopharyngeal dysfunction (VPD) compromises the outcome, and the burden of VPD remains largely unknown in low- and middle-income countries (LMICs). To scale up VPD care in these areas, we continue to explore the use of artificial intelligence (AI) and machine learning (ML) for automatic detection of VPD from speech samples alone.</p><p><strong>Methods: </strong>An age-matched, single-institution cohort of 60 patients (30 control, 30 with VPD after cleft palate repair) generated approximately 8000 audio samples (4000 VPD and 4000 control). These samples were used to inform the development of a neural network-based, self-supervised deep learning ML model.</p><p><strong>Results: </strong>ML model testing with augmented and unaugmented data sets revealed accuracies of 1.0, macro precisions of 1.0, macro recalls of 1.0, and F1 scores of 1.0.</p><p><strong>Discussion: </strong>Although these results are promising and support the ability of ML models to detect VPD, the results likely indicate that the ML models are also picking up confounding data. Efforts are underway to address this problem while simultaneously employing disentanglement tactics to allow for multilingual speech analysis. The ability to clinically operationalize such a model could instantaneously enhance VPD care in LMICs for patients with cleft palate with little changes to existing healthcare infrastructure.</p>","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":"95 3S Suppl 1","pages":"S55-S59"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145005901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rural Representation: Factors Associated With Geographic Distribution of Plastic Surgeons in Rural United States Counties.","authors":"Danielle J Sim, Siam Rezwan, Waldemar Rodriguez-Silva, Tyler Reinoso, Lily Zhu, Kelli Webb, Carisa M Cooney","doi":"10.1097/SAP.0000000000004354","DOIUrl":"10.1097/SAP.0000000000004354","url":null,"abstract":"<p><strong>Background: </strong>Residents of rural areas in the United States (US) experience health care disparities, including limited access to plastic and reconstructive surgery (PRS). This study aims to characterize the geographic distribution of board-certified plastic and reconstructive surgeons in the US and factors associated with their presence in rural areas.</p><p><strong>Methods: </strong>We identified American Society of Plastic Surgeons members in the US in December 2023. We queried the 2022 Area Health Resource File for county demographics and health resources and characterized rurality with the National Center for Health Statistics Urban-Rural Classification Scheme. We used t test, chi-squared test, and Wilcoxon rank-sum test to compare intercounty outcomes and multivariate regression to identify health resources associated with PRS.</p><p><strong>Results: </strong>We identified 3913 board-certified plastic and reconstructive surgeons who served 626 (20%) counties throughout the US, accounting for 247,988,122 (75%) people. Almost half (46%) of all urban counties had a plastic and reconstructive surgeon while only 5% of rural counties did ( P < 0.001). Access to PRS in a rural county was significantly associated with the presence of ambulatory surgery centers (adjusted odds ratio [aOR]: 1.80, P = 0.048), dermatology (aOR: 2.12, P = 0.010), and radiation oncology (aOR: 2.16, P = 0.013).</p><p><strong>Conclusions: </strong>We found significant geographic variation in PRS access throughout the country, with 95% of rural counties being without a plastic and reconstructive surgeon. Presence of an ambulatory surgery center, dermatology, and radiation oncology increased the likelihood of access to PRS in rural counties. Additional studies are needed to identify necessary resources that may help recruit plastic and reconstructive surgeons to rural areas.</p>","PeriodicalId":8060,"journal":{"name":"Annals of Plastic Surgery","volume":" ","pages":"308-314"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}