Integrative medicine : integrating conventional and alternative medicine最新文献

{"title":"Parkinson's Disease","authors":"Opher Caspi MD ,&nbsp;Cynthia Thomson PHD, RD","doi":"10.1016/S1096-2190(99)00006-2","DOIUrl":"10.1016/S1096-2190(99)00006-2","url":null,"abstract":"<div><p>Parkinson's disease<span><span><span> is a common idiopathic neurodegenerative disease affecting an increasing number of elderly people. The disease usually manifests with a classical triad of symptoms (tremor, rigidity, and akinesia) and is considered to be the result of dopamine deficiency in the brain. Among the theories to explain the ethiopathogenecity of Parkinson's disease are some endogenous mechanisms, such as mitochondrial dysfunction, </span>oxidative stress<span>, action of excitotoxins, deficient </span></span>neurotrophic factors<span>, and dysimmunity, and some environmental factors, such as undesirable nutritional status. The cornerstone of Parkinson's disease therapy is the exogenous supplementation of levodopa, the amino acid precursor of dopamine. For most patients, however, this treatment fails over time and other alternative therapies are pursued. The purpose of this paper is to explore the lines of evidence suggesting the roles for Mind–Body medicine, nutrition, and vitamin and herbal supplements in the integrative approach to the medical care of patients with Parkinson's disease. It is proposed that many parkinsonian symptoms can be treated, controlled, and even reversed by adopting such an integrative and comprehensive approach.</span></span></p></div>","PeriodicalId":80285,"journal":{"name":"Integrative medicine : integrating conventional and alternative medicine","volume":"2 1","pages":"Pages 37-42"},"PeriodicalIF":0.0,"publicationDate":"1999-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1096-2190(99)00006-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76394419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personal and professional beliefs and practices regarding herbal medicine among the full time faculty of the newark-based schools of the university of medicine and dentistry of new jersey.","authors":"Dougherty, Touger-Decker, O'Sullivan Maillet J","doi":"10.1016/S0002-8223(99)00747-6","DOIUrl":"https://doi.org/10.1016/S0002-8223(99)00747-6","url":null,"abstract":"","PeriodicalId":80285,"journal":{"name":"Integrative medicine : integrating conventional and alternative medicine","volume":"87 1","pages":"57-64"},"PeriodicalIF":0.0,"publicationDate":"1999-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76381938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unusual Improvement in Angina Pectoris Following Initiation of Coenzyme Q-10 Therapy","authors":"Joseph S. Alpert MD","doi":"10.1016/S1096-2190(98)00008-0","DOIUrl":"10.1016/S1096-2190(98)00008-0","url":null,"abstract":"","PeriodicalId":80285,"journal":{"name":"Integrative medicine : integrating conventional and alternative medicine","volume":"1 1","pages":"Pages 47-48"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1096-2190(98)00008-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89602074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prescribing Therapeutic Feverfew (Tanacetum parthenium (L.) Schultz Bip., syn. Chrysanthemum parthenium (L.) Bernh.)","authors":"Dennis V.C. Awang PHD, FCIC","doi":"10.1016/S1096-2190(98)00020-1","DOIUrl":"10.1016/S1096-2190(98)00020-1","url":null,"abstract":"<div><p>The established potential of the whole leaf of feverfew in migraine prevention has encouraged manufacturers of medicinal botanical preparations to pursue “standardization” of feverfew products. Such standardizing efforts have concentrated on the content of parthenolide<span>, the putative active principle. The almost universal acceptance of this role for parthenolide in migraine prophylaxis is based on the hypothesis that the efficacy of feverfew is due to the ability of this germacranolide sesquiterpene to inhibit release of serotonin from blood platelets. The recent publication of the results of a clinical trial using a feverfew leaf extract containing an acceptable level of parthenolide—but found ineffective as a migraine prophylactic—discredits the parthenolide hypothesis. Clearly, more research is needed into both the mechanism of migraine prevention and the identity of feverfew’s active principle(s). Meanwhile, treatment ought to be confined to the use of whole dried leaf of an appropriate variety of this plant.</span></p></div>","PeriodicalId":80285,"journal":{"name":"Integrative medicine : integrating conventional and alternative medicine","volume":"1 1","pages":"Pages 11-13"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1096-2190(98)00020-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86451727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integration As Community Organizing","authors":"John Weeks ,&nbsp;Richard Layton MD","doi":"10.1016/S1096-2190(98)00005-5","DOIUrl":"10.1016/S1096-2190(98)00005-5","url":null,"abstract":"<div><p>The leading model for integrating complementary and alternative medicine (CAM) providers and services into health care delivery and benefits plans is through contracted networks of credentialed CAM providers. The CAM benefit is usually offered for an additional fee (an insurance “rider”) with management frequently contracted (“carved out”) to an independent specialty management firm. This model, viewed by many plans as a relatively risk-free method for entering the CAM arena, is principally market or consumer driven. The authors suggest that the incentives in this model work against both integrating CAM providers into basic service delivery and in gaining an understanding of the optimal role of CAM in the broader health care system, particularly regarding questions of effectiveness, cost-effectiveness, and appropriate referral patterns to and from conventionally trained physicians. The authors share a practical, network-oriented CAM integration strategy that was developed in 1996–1997 for a multi-clinic primary care organization servicing numerous insurance contracts, each of which included benefits provided by credentialed networks of acupuncturists, chiropractors, naturopaths, massage practitioners, and midwives. The strategy focuses on what the authors call “community organizing”: determining specific interests of the providers then building, based on the “grassroots” of physicians interest, an integration strategy. The use of interactive workshops and provider surveys, as well as outcomes, are described, together with a prospective workplan for an implementation of this integration approach. An information-gathering strategy based on what the authors call “compiling observation” is then presented as a means to gain some useful, initial understanding of questions relative to the patient satisfaction, effectiveness and cost-effectiveness of CAM integration, in this context in which more thorough data on CAM interventions may not be available.</p></div>","PeriodicalId":80285,"journal":{"name":"Integrative medicine : integrating conventional and alternative medicine","volume":"1 1","pages":"Pages 15-25"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1096-2190(98)00005-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87836234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Homocysteine, Vitamin Deficiency and Prevention of Arteriosclerosis","authors":"Kilmer S. Mccully MD","doi":"10.1016/S1096-2190(98)00011-0","DOIUrl":"10.1016/S1096-2190(98)00011-0","url":null,"abstract":"<div><p><span><span><span>The homocysteine<span> theory of arteriosclerosis was discovered by study of children with </span></span>homocystinuria<span><span> caused by different enzymatic disorders of homocysteine metabolism. Deficiency of cystathionine synthase, a </span>pyridoxal phosphate dependent enzyme, causes elevated levels of plasma homocysteine. Deficiency of </span></span>methyl transferase<span><span><span><span>, a folic acid and cobalamin dependent enzyme, causes elevated levels of plasma homocysteine and cystathionine. Arteriosclerosis was discovered to be associated with homocysteinemia in both of these inherited dirorders. Because of different metabolic consequences of these two diseases, it was possible to conclude that homocysteine causes arteriosclerosis by damaging the </span>endothelial cells and producing </span>hyperplasia<span><span> of smooth muscle cells and other connective tissue changes. Deficiency of a third enzyme, </span>methylenetetrahydrofolate reductase<span>, also causes homocystinuria and arteriosclerotic plaques, providing independent evidence to support this conclusion. Further evidence to support this conclusion came from studies with animals showing that injection of homocysteine causes arteriosclerotic plaques and thrombosis that closely resemble the vascular changes in children with homocystinuria. The homocysteine theory of arteriosclerosis relates the pathogenesis of the disease in the general population to dietary deficiencies of </span></span></span>vitamin B6, folic acid, and </span></span>vitamin B12<span>. Deficiencies of these vitamins are produced by losses incurred during processing and preservation of basic foodstuffs. Population surveys have concluded that elevated levels of plasma homocysteine are an independent risk factor for arteriosclerosis, heart disease, and stroke. Elevated homocysteine levels have in turn been related to widespread deficiencies of folic acid and vitamin B6 within susceptible populations<span>. The decline in mortality from coronary heart disease in the U.S. during the past three decades is attributed to increased vitamin B6 and folic acid that were introduced into the food supply through voluntary fortification and supplementation. A properly designed intervention trial is needed to show a major reduction in cardiovascular disease risk and complications by a diet and supplementary nutrients that reduce levels of homocysteine in the plasma.</span></span></p></div>","PeriodicalId":80285,"journal":{"name":"Integrative medicine : integrating conventional and alternative medicine","volume":"1 1","pages":"Pages 3-9"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1096-2190(98)00011-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74372915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Product review","authors":"","doi":"10.1016/S1096-2190(98)00004-3","DOIUrl":"https://doi.org/10.1016/S1096-2190(98)00004-3","url":null,"abstract":"","PeriodicalId":80285,"journal":{"name":"Integrative medicine : integrating conventional and alternative medicine","volume":"1 1","pages":"Pages 43-44"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1096-2190(98)00004-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136746086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytoestrogens in Clinical Practice","authors":"Susan R. Davis MD, PHD ,&nbsp;Alice L. Murkies MD ,&nbsp;Gisela Wilcox MD","doi":"10.1016/S1096-2190(98)00019-5","DOIUrl":"10.1016/S1096-2190(98)00019-5","url":null,"abstract":"","PeriodicalId":80285,"journal":{"name":"Integrative medicine : integrating conventional and alternative medicine","volume":"1 1","pages":"Pages 27-34"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1096-2190(98)00019-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75092595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Product review","authors":"","doi":"10.1016/S1096-2190(98)00003-1","DOIUrl":"https://doi.org/10.1016/S1096-2190(98)00003-1","url":null,"abstract":"","PeriodicalId":80285,"journal":{"name":"Integrative medicine : integrating conventional and alternative medicine","volume":"1 1","pages":"Pages 41-42"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1096-2190(98)00003-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136746085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Product review","authors":"","doi":"10.1016/S1096-2190(98)00002-X","DOIUrl":"https://doi.org/10.1016/S1096-2190(98)00002-X","url":null,"abstract":"","PeriodicalId":80285,"journal":{"name":"Integrative medicine : integrating conventional and alternative medicine","volume":"1 1","pages":"Pages 39-40"},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1096-2190(98)00002-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136746087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}