Integrative medicine : integrating conventional and alternative medicine最新文献_第5页

Chaparral-Induced Hepatotoxicity Chaparral-Induced肝毒性

Integrative medicine : integrating conventional and alternative medicine Pub Date : 1998-03-01 Epub Date: 2006-04-03 DOI: 10.1016/S1096-2190(98)00026-2

Kathryn L. Grant PHARM.D., FASHP , Leslie V. Boyer MD , Boyd E. Erdman MD

{"title":"Chaparral-Induced Hepatotoxicity","authors":"Kathryn L. Grant PHARM.D., FASHP , Leslie V. Boyer MD , Boyd E. Erdman MD","doi":"10.1016/S1096-2190(98)00026-2","DOIUrl":"10.1016/S1096-2190(98)00026-2","url":null,"abstract":"<div>Background: Chaparral leaf (Larrea tridentata) has been used for centuries to treat a variety of ailments. Laboratory investigations have demonstrated the presence of at least one pharmacologically active lignan, but no controlled studies have demonstrated efficacy and safety in vivo. Recent reports suggest chaparral may cause toxic hepatitis in some chronic users.Case Report: A 27-year-old Hispanic male developed hepatitis approximately 12 months after beginning therapy with chaparral capsules. Liver biopsy showed hepatocellular injury with necrosis and periportal inflammation. Liver function stabilized 6 weeks after hepatitis was first recognized.Conclusions: Although chaparral has been associated with cholangitis, impaired synthetic function and fulminant hepatic failure, because the pattern of chaparral use is unknown, the incidence of hepatotoxicity is also unknown. Severe liver damage may be more common in patients taking higher doses for longer periods of time. Prolonged courses of chaparral should not be recommended routinely. Patients desiring to use chaparral for periods greater than two weeks should be warned of the potential for hepatotoxicity and monitored closely.</div>","PeriodicalId":80285,"journal":{"name":"Integrative medicine : integrating conventional and alternative medicine","volume":"1 2","pages":"Pages 83-87"},"PeriodicalIF":0.0,"publicationDate":"1998-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1096-2190(98)00026-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89143011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Product review 产品评论

Integrative medicine : integrating conventional and alternative medicine Pub Date : 1998-03-01 Epub Date: 2006-04-03 DOI: 10.1016/S1096-2190(98)00024-9

引用次数: 0

Efficacy and Risks of Chiropractic Manipulation 捏脊手法的疗效和风险

Integrative medicine : integrating conventional and alternative medicine Pub Date : 1998-03-01 Epub Date: 2006-04-03 DOI: 10.1016/S1096-2190(98)00015-8

Ian D Coulter PHD

{"title":"Efficacy and Risks of Chiropractic Manipulation","authors":"Ian D Coulter PHD","doi":"10.1016/S1096-2190(98)00015-8","DOIUrl":"10.1016/S1096-2190(98)00015-8","url":null,"abstract":"<div>Chiropractors account for around 90% of the manipulation in the United States, and more than 94% of chiropractic patients receive some form of manipulation. This article reports on two studies of the appropriateness of manipulation conducted at RAND using systematic literature reviews and expert panels. Two areas were focused on: manipulation for low-back pain and manipulation and mobilization of the cervical spine. The systematic review of the literature (including a meta-analysis) for the evidence for manipulation for low-back pain indicated that spinal manipulation was more efficacious than the comparison treatments for patients with acute or sub-acute low-back pain uncomplicated by sciatica. For cervical manipulation, the systematic literature review indicated efficacy for neck pain and for patients with muscle-tension-type headache. For both cervical manipulation and manipulation for low-back pain, the literature reports low levels of complications. For cervical manipulation, the estimated risk for serious complications is 6.39 per 10 million manipulations. For lumbar manipulation the estimate is 1 serious complication per 100 million manipulations. Although the evidence of the efficacy for manipulation is not overwhelming, there is sufficient evidence to establish efficacy for acute conditions and sufficient evidence to warrant serious investigation of its efficacy in other areas. The risk from manipulation is low and compares favorably to other forms of therapy for the same conditions (e.g., 15.6 complications per 1000 cervical spine surgeries, 3.2 per 1000 subjects for nonsteroidal anti-inflammatory drugs).</div>","PeriodicalId":80285,"journal":{"name":"Integrative medicine : integrating conventional and alternative medicine","volume":"1 2","pages":"Pages 61-66"},"PeriodicalIF":0.0,"publicationDate":"1998-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1096-2190(98)00015-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73888585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 25

Treatment Efficacy Of Acupuncture 针灸的治疗效果

Integrative medicine : integrating conventional and alternative medicine Pub Date : 1998-01-01 Epub Date: 1999-02-15 DOI: 10.1016/S1096-2190(98)00033-X

Robin Leake MA , Joan E Broderick PHD

{"title":"Treatment Efficacy Of Acupuncture","authors":"Robin Leake MA , Joan E Broderick PHD","doi":"10.1016/S1096-2190(98)00033-X","DOIUrl":"10.1016/S1096-2190(98)00033-X","url":null,"abstract":"<div>A growing body of scientific literature provides strong evidence for the treatment efficacy of acupuncture for several medical conditions. Although it is premature to conclude that these findings are beyond question, the quality and consistency of the research is such that it can no longer be ignored by mainstream medicine. Acupuncture holds the promise of being able to treat certain patients with chronic disease or otherwise difficult-to-treat conditions and to achieve immediate palliative effects with virtually no side effects. Results of randomized controlled trials have found acupuncture to be effective in the treatment of pain, asthma, post-operative nausea, dysmennorhea, and motor dysfunction from stroke. Suggestive evidence is documented for treatment of chemotherapy-induced nausea, substance abuse, carpal tunnel syndrome, and cerebal palsy. Recent studies have also elucidated potential physiological pathways of the treatment effect. In recognition of the increasing legitimacy of acupuncture, the Federal Drug Administration removed acupuncture needles from the category of “experimental medical devices” in 1996, and now regulates their use.</div>","PeriodicalId":80285,"journal":{"name":"Integrative medicine : integrating conventional and alternative medicine","volume":"1 3","pages":"Pages 107-115"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1096-2190(98)00033-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80873841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 46

Neurodegeneration and Aging of the Central Nervous System 中枢神经系统的神经退化和衰老

Integrative medicine : integrating conventional and alternative medicine Pub Date : 1998-01-01 Epub Date: 1999-02-15 DOI: 10.1016/S1096-2190(98)00032-8

Russell L Blaylock MD

引用次数: 17

Integrating Belief Systems and Therapies in Medicine 整合信仰系统和医学疗法

Integrative medicine : integrating conventional and alternative medicine Pub Date : 1998-01-01 Epub Date: 1999-02-15 DOI: 10.1016/S1096-2190(98)00023-7

Iris R Bell MD,MD(H), PHD , Carol M Baldwin RN, PHD , Gary E.R Schwartz PHD , Linda G.S Russek PHD

{"title":"Integrating Belief Systems and Therapies in Medicine","authors":"Iris R Bell MD,MD(H), PHD , Carol M Baldwin RN, PHD , Gary E.R Schwartz PHD , Linda G.S Russek PHD","doi":"10.1016/S1096-2190(98)00023-7","DOIUrl":"10.1016/S1096-2190(98)00023-7","url":null,"abstract":"<div>The purpose of this paper is to apply the eight world hypotheses model of science to classical homeopathy. The model identifies an interactive hierarchy of levels of thinking about nature: (1) formistic/categorical; (2) mechanistic/cause-effect; (3) contextual/relativistic; (4) organismic; (5) implicit process; (6) circular causality; (7) creative unfolding; and (8) integrative diversity. These levels represent different scientific paradigms, i.e., classical science (levels 1–2), modern science (levels 3–4), postmodern science (levels 5–6), and integrative science (levels 7–8), which help explain the variability with which mainstream medicine has begun to integrate different forms of complementary and alternative medicine (CAM). Homeopathy is one of the most comprehensive systems of CAM therapies, but to date it has received little consideration for integration. After summarizing the theory and practice of homeopathy, we use these concepts within the eight world hypotheses to provide a framework for understanding homeopathy’s past rejection by conventional medicine and for facilitating research toward the integration of homeopathy into the mainstream medicine of the future.</div>","PeriodicalId":80285,"journal":{"name":"Integrative medicine : integrating conventional and alternative medicine","volume":"1 3","pages":"Pages 95-105"},"PeriodicalIF":0.0,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1096-2190(98)00023-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76394425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11