Medicine & health最新文献_第9页

Role of Translaminar Pressure Gradient Differences in Glaucoma - A Review 层间压梯度差异在青光眼中的作用综述

Medicine & health Pub Date : 2019-12-31 DOI: 10.17576/mh.2019.1402.30

Muhammad Syamil

引用次数: 0

Characteristics and Factors Associated with Adverse Cutaneous Drug Reactions Caused by Traditional, Complementary and Conventional Medicine in Malaysia 马来西亚传统、补充和常规医学引起的皮肤药物不良反应的特点和相关因素

Medicine & health Pub Date : 2019-12-31 DOI: 10.17576/mh.2019.1402.05

L. Muthupalaniappen

{"title":"Characteristics and Factors Associated with Adverse Cutaneous Drug Reactions Caused by Traditional, Complementary and Conventional Medicine in Malaysia","authors":"L. Muthupalaniappen","doi":"10.17576/mh.2019.1402.05","DOIUrl":"https://doi.org/10.17576/mh.2019.1402.05","url":null,"abstract":"Traditional and Complimentary Medicines (TCMs) can potentially cause Adverse Cutaneous Drug Reactions (ACDRs). The aim of this study was to describe the characteristics of ACDRs due to TCMs and compare with those due to conventional medicine. This was a retrospective study with 134 cases being diagnosed with ACDR at the Dermatology Clinic of a tertiary hospital in Kuala Lumpur. Most (82.1%) ACDRs were caused by conventional drugs, while 17.9% were due to TCMs. Majority (70-75%) of the ACDRs were of mild to moderate severity. The most common ACDR to TCM was Exfoliative Dermatitis (ED) and Acute Generalized Exanthematous Pustulosis (AGEP) (both 16.7%) while maculopapular rash was the most common reaction for conventional medications (25.5%). The onset of adverse reaction to TCM was about 4 weeks (60.2%) while reactions due to conventional medication was earlier (1 to 6 days, 65.4%; p<0.05). The odds of developing delayed ACDR was 14 times more with TCM compared to conventional medicine (p<0.05). This study showed that ED and AGEP were the most common ACDR manifestations of TCM while macuplopapular rash was the most common manifestation of conventional medications. However, most of these reactions were of mild to moderate severity. ACDR due to TCM may manifest long after the initiation of these products and hence its use should be routinely inquired when patients present with skin problems. All suspected cases of ADRs to TCM should be reported to the Malaysian Adverse Drug Reactions Advisory Committee (MADRAC) for continuous pharmacovigilance of these products.","PeriodicalId":80079,"journal":{"name":"Medicine & health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43600975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection of BCR-ABL T315i Mutation in Imatinib Resistant Chronic Myeloid Leukemia Patients 伊马替尼耐药慢性髓系白血病患者BCR-ABL T315i突变的检测

Medicine & health Pub Date : 2019-06-28 DOI: 10.17576/MH.2019.1401.12

R. Sabudin

引用次数: 0

Functional Outcome of Hindfoot Arthrodesis in Charcot Arthropathy Charcot关节病后足关节固定术的功能结果

Medicine & health Pub Date : 2019-06-28 DOI: 10.17576/MH.2019.1401.14

M. Y. Bajuri

{"title":"Functional Outcome of Hindfoot Arthrodesis in Charcot Arthropathy","authors":"M. Y. Bajuri","doi":"10.17576/MH.2019.1401.14","DOIUrl":"https://doi.org/10.17576/MH.2019.1401.14","url":null,"abstract":"Charcot arthropathy is a devastating degenerative condition which affects one or more joints that is marked by joint instability, hypermobility resulted from peripheral nerve damage. This was a retrospective study performed on patients who were diagnosed with Charcot arthropathy and those underwent surgery for hindfoot arthrodesis at Universiti Kebangsaan Malaysia Medical Centre from January 2011 until June 2016. The objective of the study was to review the feasibility of an algorithm in managing Charcot arthropathy and to assess functional, clinical and radiographic outcomes of Charcot arthropathy joints treated with hindfoot arthrodesis, at least 6 months follow-up using standardized and internationally accepted scoring systems, which were the American Orthopaedic Foot and Ankle Surgery (AOFAS) score and SF36. A total of 16 patients were included in this study of which 4 (25%) were males and 12 (75%) were females. The mean age was 58.1 (20-71) years. There was equal distribution for side of fusion. We achieved union in 13 out of our 16 (81%) cases followed up. Out of the 3 patients with non-union, 2 were attributed to deep infections. The AOFAS scores for hindfoot and midfoot showed significant improvement post operatively with p-value <0.05 as well as the SF36 mental scores with p-value <0.05. The Physical Component of SF36 showed no improvement. The treatment algorithm currently used in our centre is acceptable and shows good outcomes. While the outcomes are of acceptable rates, efforts should now focus on reducing the complications as the burden of infection and non-union remains a known complication for most bone-related surgeries.","PeriodicalId":80079,"journal":{"name":"Medicine & health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45224102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Local Anaesthesia Systemic Toxicity (LAST) – A Stroke Mimicker 局部麻醉全身性毒性(LAST) -卒中模拟剂

Medicine & health Pub Date : 2019-06-28 DOI: 10.17576/MH.2019.1401.27

T. Leong

引用次数: 2

Adhesions as an Uncommon Complication of K-Wiring in Paediatric Phalangeal Fractures 粘连是儿童指骨骨折k -钢丝治疗中一种罕见的并发症

Medicine & health Pub Date : 2019-06-28 DOI: 10.17576/MH.2019.1401.18

S. Abdullah

引用次数: 0

Splenic Hilar Mass With Pain, Diarrhoea and Sweating: Can It Be Malignant? 脾门肿块伴疼痛、腹泻、出汗:可能是恶性的吗?

Medicine & health Pub Date : 2019-06-28 DOI: 10.17576/MH.2019.1401.32

F. Hayati

引用次数: 0

Tocotrienol-Rich Fraction (TRF) Improves the Viability of Wild-Type Saccharomyces cerevisiae in the Initial Stationary Phase 富三烯醇组分（TRF）提高野生型酿酒酵母在初始固定相中的活力

Medicine & health Pub Date : 2019-06-28 DOI: 10.17576/MH.2019.1401.09

K. T. Arifin

引用次数: 2

Pseudoaneurysm of Dorsalis Pedis Artery Following Lisfranc Surgery: A Rare Complication 足背动脉假性动脉瘤:一种罕见的并发症

Medicine & health Pub Date : 2019-06-28 DOI: 10.17576/MH.2019.1401.21

M. Y. Bajuri

引用次数: 1

A Crossover Study Comparing In-Plane and Outof- Plane Approaches for Simulated Ultrasound- Guided Central Venous Cannulation on Phantom Models by Anaesthesiology Trainees 模拟超声引导下麻醉学实习生在体模上进行中央静脉插管的平面内和平面外方法的交叉研究

Medicine & health Pub Date : 2019-06-28 DOI: 10.17576/MH.2019.1401.11

M. Maaya

{"title":"A Crossover Study Comparing In-Plane and Outof- Plane Approaches for Simulated Ultrasound- Guided Central Venous Cannulation on Phantom Models by Anaesthesiology Trainees","authors":"M. Maaya","doi":"10.17576/MH.2019.1401.11","DOIUrl":"https://doi.org/10.17576/MH.2019.1401.11","url":null,"abstract":"This prospective crossover study compared the incidence of posterior vessel wall puncture between two approaches during ultrasound-guided simulated central venous cannulation by anaesthesiology trainees. Each phantom model, simulating a central vein and artery, was cannulated by 37 anaesthesiology trainees under ultrasound-guidance using the in-plane approach (IPA) and out-of-plane approach (OPA). Total procedural time and the time taken from starting image scanning until commencing puncture, was recorded. The number of attempts required to achieve successful venous cannulation was noted. Finally, the models were examined for posterior venous wall and arterial puncture. Total procedural time was shorter with the OPA (26.5 vs 50.3 seconds, p=0.001). The time taken from starting image scanning until commencing puncture was shorter for the OPA (2.2 vs 12.3 seconds, p<0.0001). The IPA resulted in significantly more attempts for cannulation. Twenty and eleven participants were successful within the first pass using the OPA and IPA, respectively (p=0.034). There was no difference in the incidence of posterior vessel wall puncture between these two techniques. The OPA resulted in less arterial puncture compared to the IPA (2 vs 9, p=0.022). The incidence of posterior vessel wall puncture between the IPA and OPA during ultrasound-guided simulated central venous cannulation by anaesthesiology trainees was comparable.","PeriodicalId":80079,"journal":{"name":"Medicine & health","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41753907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0