Annals of Oncology最新文献

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53P Microsatellite-instability-high/mismatch-repair-deficient (MSI-H/dMMR) and BRAFV600E mutant (BRAFm) advanced colorectal cancers (CRC) treated with immune checkpoint inhibitors (ICI): Real-world data from the Royal Marsden Hospital 53P微卫星不稳定性-高/错配修复缺陷(MSI-H/dMMR)和BRAFV600E突变(BRAFm)晚期结直肠癌(CRC)用免疫检查点抑制剂(ICI)治疗:来自皇家马斯登医院的真实世界数据
IF 56.7 1区 医学
Annals of Oncology Pub Date : 2025-07-01 DOI: 10.1016/j.annonc.2025.05.065
H.M.L. Le, I. Chau, D. Cunningham, N. Starling, S. Rao, C. Fribbens, H. Lote
{"title":"53P Microsatellite-instability-high/mismatch-repair-deficient (MSI-H/dMMR) and BRAFV600E mutant (BRAFm) advanced colorectal cancers (CRC) treated with immune checkpoint inhibitors (ICI): Real-world data from the Royal Marsden Hospital","authors":"H.M.L. Le, I. Chau, D. Cunningham, N. Starling, S. Rao, C. Fribbens, H. Lote","doi":"10.1016/j.annonc.2025.05.065","DOIUrl":"10.1016/j.annonc.2025.05.065","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Page S30"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
30P T cell cancer cell interaction in prediction of response to EGFR-, VEGF-inhibitors or no biologics in first-line treatment of metastatic colorectal cancer (mCRC) patients 30P T细胞癌细胞相互作用预测转移性结直肠癌(mCRC)患者一线治疗中对EGFR-、vegf -抑制剂或无生物制剂的反应
IF 56.7 1区 医学
Annals of Oncology Pub Date : 2025-07-01 DOI: 10.1016/j.annonc.2025.05.042
P.J. Osterlund , A. Martin Bernabe , M. Mäkinen , J. Sundström , L. Nieminen , J.P. Väyrynen , V. Kärjä , J. Böhm , M. Ahtiainen , H. Isoniemi , P. Halonen , T. Salminen , A. Algars , R. Kallio , A. Lamminmäki , A. Östman , A. Ristimäki , T. Pellinen
{"title":"30P T cell cancer cell interaction in prediction of response to EGFR-, VEGF-inhibitors or no biologics in first-line treatment of metastatic colorectal cancer (mCRC) patients","authors":"P.J. Osterlund , A. Martin Bernabe , M. Mäkinen , J. Sundström , L. Nieminen , J.P. Väyrynen , V. Kärjä , J. Böhm , M. Ahtiainen , H. Isoniemi , P. Halonen , T. Salminen , A. Algars , R. Kallio , A. Lamminmäki , A. Östman , A. Ristimäki , T. Pellinen","doi":"10.1016/j.annonc.2025.05.042","DOIUrl":"10.1016/j.annonc.2025.05.042","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Pages S17-S18"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
40P Encorafenib plus cetuximab in patients with metastatic, BRAF V600E-mutated, colorectal carcinoma - Effectiveness and treatment reality of the European multi-centric, multi-national, non-interventional study: BERING CRC enorafenib联合西妥昔单抗治疗转移性、BRAF v600e突变的结直肠癌——欧洲多中心、多国、非介入性研究:BERING CRC的有效性和治疗现状
IF 56.7 1区 医学
Annals of Oncology Pub Date : 2025-07-01 DOI: 10.1016/j.annonc.2025.05.052
S. Stintzing , H. Müller-Huesmann , E. von der Heyde , I. Virchow , R. Greil , J. Kisro , P. Stübs , D. Buerkle , A. Distelrath , J. Wierecky , A. Wein , A. Gerger , D. Arnold , R.M. Fritsch , S. Hegewisch-Becker , A. Vogel , A.D. Wagner , T. Winder , D. Koeberle , G. Prager
{"title":"40P Encorafenib plus cetuximab in patients with metastatic, BRAF V600E-mutated, colorectal carcinoma - Effectiveness and treatment reality of the European multi-centric, multi-national, non-interventional study: BERING CRC","authors":"S. Stintzing , H. Müller-Huesmann , E. von der Heyde , I. Virchow , R. Greil , J. Kisro , P. Stübs , D. Buerkle , A. Distelrath , J. Wierecky , A. Wein , A. Gerger , D. Arnold , R.M. Fritsch , S. Hegewisch-Becker , A. Vogel , A.D. Wagner , T. Winder , D. Koeberle , G. Prager","doi":"10.1016/j.annonc.2025.05.052","DOIUrl":"10.1016/j.annonc.2025.05.052","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Page S25"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144634305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
37P Efficacy and safety of fruquintinib vs placebo by metastatic site in metastatic colorectal cancer: A FRESCO-2 subgroup analysis 氟喹替尼与安慰剂在转移性结直肠癌转移部位的疗效和安全性:FRESCO-2亚组分析
IF 56.7 1区 医学
Annals of Oncology Pub Date : 2025-07-01 DOI: 10.1016/j.annonc.2025.05.049
R. Garcia-Carbonero , N.A. Dasari , C. Eng , E. Elez Fernandez , T. Yoshino , D. Arnold , S. Lonardi , P. García Alfonso , J.C. Yao , D. Tougeron , G. Chong , W. Schelman , Z. Yu , L. Chen , C. Cremolini
{"title":"37P Efficacy and safety of fruquintinib vs placebo by metastatic site in metastatic colorectal cancer: A FRESCO-2 subgroup analysis","authors":"R. Garcia-Carbonero , N.A. Dasari , C. Eng , E. Elez Fernandez , T. Yoshino , D. Arnold , S. Lonardi , P. García Alfonso , J.C. Yao , D. Tougeron , G. Chong , W. Schelman , Z. Yu , L. Chen , C. Cremolini","doi":"10.1016/j.annonc.2025.05.049","DOIUrl":"10.1016/j.annonc.2025.05.049","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Pages S22-S23"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144634344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
61P Correlation between survival outcomes and duration of sequential treatment with regorafenib and trifluridine/tipiracil for refractory metastatic colorectal cancer: Results from the multicenter retrospective ReTrITA study reorafenib和trifluridine/tipiracil序贯治疗难治性转移性结直肠癌的生存结果与持续时间的相关性:来自多中心回顾性ReTrITA研究的结果
IF 56.7 1区 医学
Annals of Oncology Pub Date : 2025-07-01 DOI: 10.1016/j.annonc.2025.05.073
C. Signorelli , A. Anghelone , M.A. Calegari , A. Passardi , A. Bittoni , J. Lucchetti , I.V. Zurlo , C. Morelli , E. Dell'Aquila , D. Gemma , A. Emiliani , G. Arrivi , F. Zoratto , M.G. Chilelli , M.G. Morandi , F. Santamaria , A. Cosimati , R. Saltarelli , E. Lucci Cordisco , M. Basso
{"title":"61P Correlation between survival outcomes and duration of sequential treatment with regorafenib and trifluridine/tipiracil for refractory metastatic colorectal cancer: Results from the multicenter retrospective ReTrITA study","authors":"C. Signorelli , A. Anghelone , M.A. Calegari , A. Passardi , A. Bittoni , J. Lucchetti , I.V. Zurlo , C. Morelli , E. Dell'Aquila , D. Gemma , A. Emiliani , G. Arrivi , F. Zoratto , M.G. Chilelli , M.G. Morandi , F. Santamaria , A. Cosimati , R. Saltarelli , E. Lucci Cordisco , M. Basso","doi":"10.1016/j.annonc.2025.05.073","DOIUrl":"10.1016/j.annonc.2025.05.073","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Page S34"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144634392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
91P Enumeration and immunophenotype of circulating tumor cells in colorectal cancer patients 91P结直肠癌患者循环肿瘤细胞计数及免疫表型分析
IF 56.7 1区 医学
Annals of Oncology Pub Date : 2025-07-01 DOI: 10.1016/j.annonc.2025.05.103
A. Paz , A. Iliopoulos , P. Apostolou , E. Hatzidaki , I. Papasotiriou
{"title":"91P Enumeration and immunophenotype of circulating tumor cells in colorectal cancer patients","authors":"A. Paz , A. Iliopoulos , P. Apostolou , E. Hatzidaki , I. Papasotiriou","doi":"10.1016/j.annonc.2025.05.103","DOIUrl":"10.1016/j.annonc.2025.05.103","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Page S45"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
92P Real-world evidence of a tissue-free ctDNA-based minimal residual disease (MRD) testing in colorectal cancer (CRC): Insights from an Indian cohort 基于无组织ctdna的结直肠癌最小残留病(MRD)检测的真实证据:来自印度队列的见解
IF 56.7 1区 医学
Annals of Oncology Pub Date : 2025-07-01 DOI: 10.1016/j.annonc.2025.05.104
V. Lavingia , S. Patil , N. Rohatgi , S. Dattatreya Palanki , V. Muddu , S. Vivek , A. Dhar , S. Sardana , A. Sharma , P.K. Julka , R. Bharat , N. Joshi , N. Sandhir , S.S. Jain
{"title":"92P Real-world evidence of a tissue-free ctDNA-based minimal residual disease (MRD) testing in colorectal cancer (CRC): Insights from an Indian cohort","authors":"V. Lavingia , S. Patil , N. Rohatgi , S. Dattatreya Palanki , V. Muddu , S. Vivek , A. Dhar , S. Sardana , A. Sharma , P.K. Julka , R. Bharat , N. Joshi , N. Sandhir , S.S. Jain","doi":"10.1016/j.annonc.2025.05.104","DOIUrl":"10.1016/j.annonc.2025.05.104","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Page S45"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
8P Botensilimab plus balstilimab in an expanded cohort of 123 patients with metastatic microsatellite-stable colorectal cancer and no active liver metastases Botensilimab + balstiliumab在123例转移性微卫星稳定型结直肠癌且无活动性肝转移患者的扩展队列研究
IF 56.7 1区 医学
Annals of Oncology Pub Date : 2025-07-01 DOI: 10.1016/j.annonc.2025.05.020
B.L. Schlechter , M. Fakih , A.M. Tsimberidou , A. Bullock , A. Pimentel , S. Sharma , H.J. Lenz , M. Gordon , G.K. Abou-Alfa , T. Marron , R.W. Lentz , I. Chau , D. Chand , M. Avagyan , W. Wu , B. Johnson , J. Grossman , S.J. O'Day , A.B. El-Khoueiry , N.H. Segal
{"title":"8P Botensilimab plus balstilimab in an expanded cohort of 123 patients with metastatic microsatellite-stable colorectal cancer and no active liver metastases","authors":"B.L. Schlechter , M. Fakih , A.M. Tsimberidou , A. Bullock , A. Pimentel , S. Sharma , H.J. Lenz , M. Gordon , G.K. Abou-Alfa , T. Marron , R.W. Lentz , I. Chau , D. Chand , M. Avagyan , W. Wu , B. Johnson , J. Grossman , S.J. O'Day , A.B. El-Khoueiry , N.H. Segal","doi":"10.1016/j.annonc.2025.05.020","DOIUrl":"10.1016/j.annonc.2025.05.020","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Pages S7-S8"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
74P Deciphering the proteomic landscape of pregnancy-associated colorectal cancer 解析妊娠相关结直肠癌的蛋白质组学景观
IF 56.7 1区 医学
Annals of Oncology Pub Date : 2025-07-01 DOI: 10.1016/j.annonc.2025.05.086
I. Ben-Aharon , A. Alpert , N. Shirron , Y. Shirman , T.G. Goshen - Lago , E. Shacham Shmueli , F.A. Peccatori
{"title":"74P Deciphering the proteomic landscape of pregnancy-associated colorectal cancer","authors":"I. Ben-Aharon , A. Alpert , N. Shirron , Y. Shirman , T.G. Goshen - Lago , E. Shacham Shmueli , F.A. Peccatori","doi":"10.1016/j.annonc.2025.05.086","DOIUrl":"10.1016/j.annonc.2025.05.086","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Pages S39-S40"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
14P Comprehensive genomic profiling to guide personalized targeted and immunotherapy in gastrointestinal tumors: Subgroup analysis of the ROME trial 14P综合基因组图谱用于指导胃肠道肿瘤的个性化靶向和免疫治疗:ROME试验的亚组分析
IF 56.7 1区 医学
Annals of Oncology Pub Date : 2025-07-01 DOI: 10.1016/j.annonc.2025.05.026
C. Cremolini , A. Botticelli , S. Scagnoli , S. Verkhovskaia , E. Crimini , F. Mazzuca , V. Guarneri , S. Tamberi , L. Fornaro , U. De Giorgi , G. Blandino , E. Capoluongo , G. Pruneri , B. Cerbelli , U. Malapelle , G. D'Amati , M. Biffoni , G. Curigliano , P. Marchetti , S. Lonardi
{"title":"14P Comprehensive genomic profiling to guide personalized targeted and immunotherapy in gastrointestinal tumors: Subgroup analysis of the ROME trial","authors":"C. Cremolini , A. Botticelli , S. Scagnoli , S. Verkhovskaia , E. Crimini , F. Mazzuca , V. Guarneri , S. Tamberi , L. Fornaro , U. De Giorgi , G. Blandino , E. Capoluongo , G. Pruneri , B. Cerbelli , U. Malapelle , G. D'Amati , M. Biffoni , G. Curigliano , P. Marchetti , S. Lonardi","doi":"10.1016/j.annonc.2025.05.026","DOIUrl":"10.1016/j.annonc.2025.05.026","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Pages S10-S11"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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