Annals of OncologyPub Date : 2025-07-01DOI: 10.1016/j.annonc.2025.05.056
A. Sartore Bianchi , G. Mauri , T. Troiani , F. Bergamo , V. Gori , S. Ghezzi , K. Bencardino , A. Amatu , S. Mariano , F.M. Tosi , E. Valtorta , C. Lauricella , P.P. Vitiello , S. Marsoni , A. Bardelli , L. Trusolino , E. Bonoldi , S. Lonardi , E. Martinelli , S. Siena
{"title":"44P Rechallenge with anti-HER2 regimens in metastatic colorectal cancer: The retrospective RHEA study","authors":"A. Sartore Bianchi , G. Mauri , T. Troiani , F. Bergamo , V. Gori , S. Ghezzi , K. Bencardino , A. Amatu , S. Mariano , F.M. Tosi , E. Valtorta , C. Lauricella , P.P. Vitiello , S. Marsoni , A. Bardelli , L. Trusolino , E. Bonoldi , S. Lonardi , E. Martinelli , S. Siena","doi":"10.1016/j.annonc.2025.05.056","DOIUrl":"10.1016/j.annonc.2025.05.056","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Page S27"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144634596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of OncologyPub Date : 2025-07-01DOI: 10.1016/j.annonc.2025.05.021
B.L. Schlechter , C.H. Lieu , M. Fakih , R. Surana , D. Chen , E.K. Rowinsky , V.X. Lu , L. Xiao , A. Venook , K. Ng , B. Keenan
{"title":"9P Phase I dose-escalation study of GCC19CART: A novel CAR T cell therapy for metastatic colorectal cancer in the United States","authors":"B.L. Schlechter , C.H. Lieu , M. Fakih , R. Surana , D. Chen , E.K. Rowinsky , V.X. Lu , L. Xiao , A. Venook , K. Ng , B. Keenan","doi":"10.1016/j.annonc.2025.05.021","DOIUrl":"10.1016/j.annonc.2025.05.021","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Page S8"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of OncologyPub Date : 2025-07-01DOI: 10.1016/j.annonc.2025.05.064
E. Christodoulis , A. Walker , A. Angelakas , K.V. Kamposioras , N. Alam , M. Braun , R. Broadbent , J. Hasan , V. Lavin , F.E. Marti , M.P. Saunders , S. Mullamitha
{"title":"52P Pembrolizumab real-world data, including inflammatory indices in dMMR/MSI-H mCRC from a tertiary cancer centre","authors":"E. Christodoulis , A. Walker , A. Angelakas , K.V. Kamposioras , N. Alam , M. Braun , R. Broadbent , J. Hasan , V. Lavin , F.E. Marti , M.P. Saunders , S. Mullamitha","doi":"10.1016/j.annonc.2025.05.064","DOIUrl":"10.1016/j.annonc.2025.05.064","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Page S30"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of OncologyPub Date : 2025-07-01DOI: 10.1016/j.annonc.2025.05.105
Y. Nakamura , J.G. Reiter , P. Natarajan , J. Joshi , P. Srinivasan , Y. Lin , W-C. Chan , T. Tin , S. Sharma , A. Jurdi , M.C. Liu , T. Kawli , A. Aleshin , T. Yoshino
{"title":"93P Clinical validation of a methylation-based, tissue-free colorectal cancer test for the detection of molecular residual disease by circulating tumor DNA","authors":"Y. Nakamura , J.G. Reiter , P. Natarajan , J. Joshi , P. Srinivasan , Y. Lin , W-C. Chan , T. Tin , S. Sharma , A. Jurdi , M.C. Liu , T. Kawli , A. Aleshin , T. Yoshino","doi":"10.1016/j.annonc.2025.05.105","DOIUrl":"10.1016/j.annonc.2025.05.105","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Page S46"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of OncologyPub Date : 2025-07-01DOI: 10.1016/j.annonc.2025.05.024
F. Jaulin , J. Cartry , S. Bedja , M-L. Tanguy , J.R. Mathieu , A. Mouawia , M. Annereau , V. Boige , A. Fuera , M. Valery , T. de Baere , S.M. Le Sourd , D. Botsen , D. Pannier , S. Pernot , A. Hollebecque , C. Smolenschi , D. Malka , A. Boileve , M.P. Ducreux
{"title":"12P ORGANOTREAT-01: A pioneer phase I/II multicenter trial of organoid-driven precision medicine for refractory colorectal cancer","authors":"F. Jaulin , J. Cartry , S. Bedja , M-L. Tanguy , J.R. Mathieu , A. Mouawia , M. Annereau , V. Boige , A. Fuera , M. Valery , T. de Baere , S.M. Le Sourd , D. Botsen , D. Pannier , S. Pernot , A. Hollebecque , C. Smolenschi , D. Malka , A. Boileve , M.P. Ducreux","doi":"10.1016/j.annonc.2025.05.024","DOIUrl":"10.1016/j.annonc.2025.05.024","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Pages S9-S10"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144634242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of OncologyPub Date : 2025-07-01DOI: 10.1016/j.annonc.2025.05.094
G. Mauri , A. Sogari , G. Crisafulli , L. Monti , G.M. Cavestro , M. Puzzono , S. Mariano , F.M. Tosi , E.F. Bonazzina , K. Bencardino , A. Amatu , S. Ghezzi , M.C. Aquilano , E. Bonoldi , S. Arena , S. Siena , A. Bardelli , A. Sartore Bianchi
{"title":"82P Intratumoral presence of the genotoxic gut bacteria pks+ E. coli in very early onset colorectal cancer","authors":"G. Mauri , A. Sogari , G. Crisafulli , L. Monti , G.M. Cavestro , M. Puzzono , S. Mariano , F.M. Tosi , E.F. Bonazzina , K. Bencardino , A. Amatu , S. Ghezzi , M.C. Aquilano , E. Bonoldi , S. Arena , S. Siena , A. Bardelli , A. Sartore Bianchi","doi":"10.1016/j.annonc.2025.05.094","DOIUrl":"10.1016/j.annonc.2025.05.094","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Page S42"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144634309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of OncologyPub Date : 2025-07-01DOI: 10.1016/j.annonc.2025.05.037
W.K. Liu , D. Sritharan , R. Cox , V. Jeyachandran , H. Yan , M. Aquino , N. Ekpemandu , D. Falaju , N. Ahmed , R. Jebaratnam , P. Velikova , G. Soosaipillai , N. Maisey , J. de Naurois , J. Roca Pallin , P.J. Ross , K. Naidoo , N. Murugaesu
{"title":"25P Reflex molecular biomarker testing in colorectal cancer: Pathway insights from the South-East England network","authors":"W.K. Liu , D. Sritharan , R. Cox , V. Jeyachandran , H. Yan , M. Aquino , N. Ekpemandu , D. Falaju , N. Ahmed , R. Jebaratnam , P. Velikova , G. Soosaipillai , N. Maisey , J. de Naurois , J. Roca Pallin , P.J. Ross , K. Naidoo , N. Murugaesu","doi":"10.1016/j.annonc.2025.05.037","DOIUrl":"10.1016/j.annonc.2025.05.037","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Page S16"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144634449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of OncologyPub Date : 2025-07-01DOI: 10.1016/j.annonc.2025.05.013
E. Elez Fernandez , T. André , S. Lonardi , H.J. Lenz , Y. Touchefeu , E. Van Cutsem , R. Garcia-Carbonero , D. Tougeron , G.A. Mendez , M. Schenker , C. de la Fouchardiere , T. Yoshino , J. Li , F.M. Aubin , E. Cela , H. Sheng , S.I. Blum , K. Davé , L. Jin , L.H. Jensen
{"title":"1O Nivolumab (NIVO) plus ipilimumab (IPI) vs NIVO monotherapy for microsatellite instability-high/mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC): Health-related quality of life (HRQoL) analyses from CheckMate 8HW","authors":"E. Elez Fernandez , T. André , S. Lonardi , H.J. Lenz , Y. Touchefeu , E. Van Cutsem , R. Garcia-Carbonero , D. Tougeron , G.A. Mendez , M. Schenker , C. de la Fouchardiere , T. Yoshino , J. Li , F.M. Aubin , E. Cela , H. Sheng , S.I. Blum , K. Davé , L. Jin , L.H. Jensen","doi":"10.1016/j.annonc.2025.05.013","DOIUrl":"10.1016/j.annonc.2025.05.013","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Pages S1-S3"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144634474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of OncologyPub Date : 2025-07-01DOI: 10.1016/j.annonc.2025.05.061
K.Y. Lai , E.Y.T. Wong , M.S. So , W. Lai , S.B. Tay , S. Han , D.Q.Q. Chong , C.W.L. Chua , S-L. Koo , I. Tan Bee Huat , B.B.Y. Ma , K.M. Cheung
{"title":"49P A multicentre propensity score matched analysis comparing maintenance strategies and treatment-break after first-line induction therapy for metastatic colorectal cancer","authors":"K.Y. Lai , E.Y.T. Wong , M.S. So , W. Lai , S.B. Tay , S. Han , D.Q.Q. Chong , C.W.L. Chua , S-L. Koo , I. Tan Bee Huat , B.B.Y. Ma , K.M. Cheung","doi":"10.1016/j.annonc.2025.05.061","DOIUrl":"10.1016/j.annonc.2025.05.061","url":null,"abstract":"","PeriodicalId":8000,"journal":{"name":"Annals of Oncology","volume":"36 ","pages":"Page S29"},"PeriodicalIF":56.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144631083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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